malano 80mg injection - Artemether (80mg) medicine

Artimisa 80mg Injection: Complete Guide to Uses, Side Effects, and Safety

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🏭 SPM Drugs Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for severe malaria.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe dizziness or fainting
  • Irregular heartbeat or palpitations
  • Yellowing of skin or eyes
  • Severe abdominal pain
  • Unusual bleeding or bruising
  • Seizures or confusion

If experiencing severe symptoms, call emergency services immediately.

What is malano 80mg injection used for?

This medicine is an injectable antimalarial containing Artemether 80mg. It is used for the treatment of severe malaria and is administered by a healthcare professional.

  • Generic Name: Artemether (80mg)
  • Manufacturer: SPM Drugs Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 malano 80mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा मलेरिया के गंभीर मामलों के इलाज के लिए इस्तेमाल की जाती है। यह आर्टेमेथर नामक तत्व से बनी है और इसे इंजेक्शन के रूप में डॉक्टर द्वारा दिया जाता है। यह मलेरिया परजीवी को मारकर काम करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन की जगह पर दर्द, बुखार, सिरदर्द, चक्कर आना, जी मिचलाना, उल्टी और पेट दर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, दिल की धड़कन में गड़बड़ी और लीवर की समस्या हो सकती है। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल योग्य डॉक्टर द्वारा दी जानी चाहिए। इसे स्वयं न लगाएं। अपने डॉक्टर को अपनी सभी दवाओं और एलर्जी के बारे में बताएं। इलाज के दौरान शराब न पिएं। यदि आप गर्भवती या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। चक्कर आने पर वाहन न चलाएं।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 malano 80mg injection Uses & Benefits

[{"condition":"Severe malaria","description":"This medicine is used for the treatment of severe malaria caused by Plasmodium falciparum, especially when oral therapy is not feasible.","evidence":"Well-established"},{"condition":"Complicated malaria","description":"It is indicated for complicated malaria cases requiring parenteral therapy.","evidence":"Well-established"},{"condition":"Cerebral malaria","description":"This medicine is effective in treating cerebral malaria, a severe complication of malaria.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Not established from the available information.","description":"Not established from the available information.","evidence":"Not established from the available information."}]

Primary treatment for: Malaria

Also treats: Cerebral malaria, Severe malaria

📋 Drug Information

Generic Name(s)Artemether (80mg)
Brand Namemalano 80mg injection
ManufacturerSPM Drugs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI MALARIALS
Action ClassAntimalarial- Artemisinin and derivatives
Route of AdministrationParenteral (intramuscular injection)
StorageStore below 30°C, protected from light. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineThe World Health Organization recommends artemether for the treatment of severe malaria. This medicine should be used as part of a comprehensive treatment plan.
ICMR GuidelineThe Indian Council of Medical Research recommends artemether for severe malaria cases. Consult local guidelines for specific recommendations.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine only in a healthcare setting with proper monitoring.
2
Monitor for allergic reactions during and after injection.
3
Check ECG before and during treatment if patient has cardiac risk factors.
4
Ensure adequate hydration and nutrition during treatment.
5
Complete the full course as prescribed to prevent recurrence.
6
Report any unusual symptoms immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High fever with chills
This medicine is used for severe malaria which presents with these symptoms.
Likely Use
❌
Headache
This medicine is not a primary headache treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionArtemether is administered intramuscularly and is rapidly absorbed from the injection site. Peak plasma concentrations are typically reached within a few hours.
DistributionArtemether is widely distributed in the body, but specific volume of distribution data are not established from the available information.
Protein BindingNot established from the available information.
MetabolismArtemether is metabolized in the liver, primarily by cytochrome P450 enzymes, to its active metabolite dihydroartemisinin.
Half-LifeThe elimination half-life of artemether is approximately 2-3 hours, while its active metabolite dihydroartemisinin has a half-life of about 1-2 hours.
ExcretionArtemether and its metabolites are excreted mainly in the bile and urine.
BioavailabilityNot established from the available information.
Onset of ActionThe onset of action is rapid, with a significant reduction in parasitemia within hours of administration.
Peak Plasma TimePeak plasma concentrations are typically reached within 1-2 hours after intramuscular injection.
Duration of ActionThe duration of action is not precisely established, but the antimalarial effect lasts for at least 24 hours, requiring repeat dosing.

How It Works

Artemether is an antimalarial agent that works by generating free radicals within the malaria parasite. These free radicals alkylate and damage parasite proteins and membranes, leading to parasite death. It is particularly effective against the blood stages of Plasmodium species.

Mechanism Steps

1
Activation by heme: Inside the malaria parasite, artemether is activated by heme iron, which is released from hemoglobin digestion.
2
Free radical generation: Activated artemether generates free radicals that alkylate and damage parasite proteins and membranes.
3
Parasite death: The damage leads to parasite death and clearance from the bloodstream.

💡 How to Take malano 80mg injection

Strength: Injection: 80mg

1This medicine is given by a healthcare professional as an intramuscular injection.
2It is typically administered in a hospital or clinic setting.
3Do not attempt to self-administer.
4Follow the prescribed schedule exactly.
5Report any side effects to your doctor immediately.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 80mg administered intramuscularly, followed by additional doses as prescribed by the doctor. The exact dosing regimen depends on the severity of malaria and the patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal and hepatic function. Consult a doctor.
Renal ImpairmentNo specific dose adjustment is established for renal impairment. Use with caution and monitor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be needed. Consult a doctor.
Maximum Daily DoseThe maximum daily dose is not established from the available information. Follow the prescribed regimen.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
No specific restriction
This medicine is given as an injection, so food timing does not affect it.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 If a dose is missed
→ Contact your doctor immediately for guidance.
💡 Do not attempt to self-administer.

⚠️ Side Effects of malano 80mg injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Apply a cold compress to the injection site. Consult doctor if pain persists.
Fever (Common (5-10%))
Stay hydrated and use paracetamol if needed. Consult doctor if fever is high or persistent.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if headache is severe or persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery. Consult doctor if dizziness persists.
Nausea (Common (5-10%))
Take small, frequent meals. Consult doctor if nausea is severe.
Vomiting (Common (5-10%))
Stay hydrated with oral rehydration solutions. Consult doctor if vomiting persists.
Abdominal pain (Common (5-10%))
Rest and avoid heavy meals. Consult doctor if pain is severe.
Loss of appetite (Common (5-10%))
Eat small, frequent meals. Consult doctor if appetite loss persists.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek immediate medical attention if you experience difficulty breathing, swelling of face or throat, or a sudden drop in blood pressure.
QT prolongation (Rare (<0.1%))
Seek immediate medical attention if you experience palpitations, fainting, or irregular heartbeat.
Hepatitis (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Blood disorders (Rare (<0.1%))
Seek immediate medical attention if you experience unusual bleeding or bruising, or signs of infection.

⚠️ Rare Side Effects

Seizures
Seek immediate medical attention.
Psychosis
Seek immediate medical attention.
Severe skin reactions
Seek immediate medical attention.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Amiodarone Major
Ketoconazole Major
Rifampicin Major
Warfarin Moderate
Antacids Minor

🚨 Major Interactions

  • QT-prolonging drugs (e.g., amiodarone, sotalol)
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • CYP3A4 inducers (e.g., rifampicin, carbamazepine)

⚡ Moderate Interactions

  • Anticoagulants (e.g., warfarin)
  • Antidiabetics

🍷 Alcohol Interaction

Avoid alcohol while receiving this medicine as it may increase the risk of liver toxicity and worsen side effects such as dizziness and nausea.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to artemether or other artemisinin derivatives","First trimester of pregnancy (unless life-threatening)","Severe liver disease","Concurrent use with QT-prolonging drugs (relative)"]

⚠️ Warnings & Precautions

["Administer only under medical supervision.","Avoid in patients with known allergies to artemisinins.","Use with caution in patients with heart rhythm disorders.","Monitor liver function in prolonged use.","Avoid alcohol during treatment.","Do not self-administer."]

🤱 Lactation Safety

It is not known whether artemether passes into breast milk. Consult your doctor before breastfeeding while receiving this medicine.

💊 Overdose Management

Overdose of this medicine may cause severe side effects. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

Since this medicine is administered by a healthcare professional, missed doses are unlikely. If a dose is missed, contact your doctor immediately for guidance.

Additional Safety Advice

General Safety

This medicine must only be given by a qualified healthcare professional. Do not attempt to self-administer. Inform your doctor if you are allergic to artemether or any other medicines. Tell your doctor about all other medicines you are taking, especially those that affect heart rhythm, as this medicine can interact with them. Avoid alcohol during treatment as it may worsen side effects. If you are pregnant or breastfeeding, consult your doctor before receiving this medicine. This medicine may cause dizziness; avoid driving or operating machinery until you know how it affects you. Complete the full course as prescribed by your doctor, even if you feel better. Do not share this medicine with others.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects. Dose adjustment may be needed based on liver and kidney function. Monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before receiving this medicine. It is generally considered safe in the second and third trimesters.

🏥 Post-Surgery Considerations

Consult your doctor before receiving this medicine after surgery. It may interact with other medications or affect recovery.

🦷 Dental Procedures

Inform your dentist if you are receiving this medicine. No specific precautions are established, but good communication is important.

💚 Lifestyle Tips for Better Results

🏃
Get plenty of rest during treatment.
🥗
Stay hydrated by drinking fluids.
😴
Eat a balanced diet to aid recovery.
💧
Avoid alcohol during treatment.
🧘
Follow up with your doctor as advised.

🏋️ Exercise Considerations

Avoid strenuous exercise until you have fully recovered from malaria. Consult your doctor before resuming intense physical activity.

🥗 Diet Recommendations

Drink plenty of fluids
Eat light, nutritious meals
Avoid alcohol
Include fruits and vegetables

💼 Impact on Daily Work & Life

This medicine may cause dizziness and fatigue. Avoid driving or operating machinery until you feel fully recovered. Take adequate rest.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Complete the full course as prescribed to prevent recurrence of malaria.

📅 Long-Term Use Effects

Long-term effects of this medicine are not well established as it is typically used for short-term treatment of severe malaria. Prolonged use may increase the risk of liver and heart effects. Regular monitoring is advised if extended therapy is required.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Artesunate injection

Another artemisinin derivative used for severe malaria.

Evidence: Well-established
Quinine injection

An older antimalarial used for severe malaria.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. Consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store below 30°C

❌ DON'T

Do not freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Protect from light

❌ DON'T

Do not store in direct sunlight

✈️ Traveling with This Medicine

If you are traveling and need this medicine, carry it in its original packaging with a copy of your prescription. Store it below 30°C and protect it from light. Since it is an injection, it must be administered by a healthcare professional. Check customs regulations for carrying injectable medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with severe malaria
He was admitted with high fever and chills. He received Artimisa 80mg injection as prescribed. His fever subsided within 48 hours and parasite count dropped significantly. He completed the course and recovered fully.
💡 Lesson: Timely administration of this medicine can rapidly control severe malaria.
👤 A 28-year-old pregnant woman in her second trimester
She was diagnosed with severe malaria. After consulting with her doctor, she received Artimisa 80mg injection. Both mother and baby remained safe, and she recovered well.
💡 Lesson: This medicine can be used in pregnancy when benefits outweigh risks, under medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within hours, but full recovery may take a few days. Follow your doctor's instructions.

Q: Can I take this medicine if I am pregnant?

A: Consult your doctor. It may be used if the benefits outweigh the risks, especially in severe malaria.

Q: What should I do if I experience side effects?

A: Report any side effects to your doctor immediately. Serious side effects require urgent medical attention.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine at home?
  • How long does the treatment last?
  • What if I miss a dose?
  • Is it safe in pregnancy?
  • Can I drink alcohol while on this medicine?
  • What are the serious side effects?

🔄 Substitutes for malano 80mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Artimisa 80mg injection can be self-administered.
    Fact: This medicine must only be given by a healthcare professional.
  • Myth: Artimisa 80mg injection is safe for all types of malaria.
    Fact: It is specifically for severe malaria and should not be used for uncomplicated cases.

🔄 Alternative Options

Generic Alternatives

  • Artemether 80mg injection

Brand Alternatives

  • Artimisa 80mg injection

📊 Comparison with Similar Medicines

[{"medicine":"Artimisa 80mg injection","active_ingredient":"Artemether 80mg","route":"Intramuscular","primary_use":"Severe malaria"},{"medicine":"Artesunate injection","active_ingredient":"Artesunate","route":"Intravenous","primary_use":"Severe malaria"}]

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