Bupicaine Injection (Bupivacaine 0.5% w/v) - Uses, Price, Side Effects
What is bupicaine injection used for?
Bupicaine Injection contains Bupivacaine 0.5% w/v, a local anesthetic used to numb specific areas of the body during surgery, dental procedures, or for pain management. It works by blocking nerve signals in the targeted area, providing temporary loss of sensation.
- Generic Name: Bupivacaine
- Manufacturer: SPM Drugs Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Category C
- Prescription Required: Yes
💊 bupicaine injection Uses & Benefits
Spinal anesthesia for lower abdominal, pelvic, and lower limb surgeries; epidural anesthesia; peripheral nerve blocks.
Off-label uses: Intra-articular injection for postoperative pain; intravenous regional anesthesia (Bier block).
📋 Drug Information
| Generic Name(s) | Bupivacaine |
| Brand Name | Anawin Heavy 5mg Injection |
| Manufacturer | SPM Drugs Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Local anaesthetic (Amides) |
| Route of Administration | Intrathecal (spinal), epidural, peripheral nerve block |
| Storage | Store at 20-25°C; protect from light; do not freeze. |
| Shelf Life | As per manufacturer |
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Blocks sodium channels in nerve cell membranes, inhibiting nerve impulse conduction.
Mechanism Steps
💡 How to Take bupicaine injection
Follow your doctor's prescription exactly.
Dosage Timeline
⚠️ Side Effects of bupicaine injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Lidocaine | Moderate | Increased risk of cardiotoxicity |
| Epinephrine | Moderate | Increased blood pressure and heart rate |
| Cimetidine | Minor | Reduced clearance of bupivacaine |
🚨 Major Interactions
- Class I antiarrhythmics
- Other local anesthetics
- CYP3A4 inhibitors
⚡ Moderate Interactions
- Beta-blockers
- Calcium channel blockers
- Antihypertensives
🍷 Alcohol Interaction
May increase CNS depression; avoid excessive alcohol.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to bupivacaine or amide anesthetics, severe hypotension, complete heart block, spinal deformities, infection at injection site.
🤱 Lactation Safety
Excreted in breast milk in small amounts; use with caution.
💊 Overdose Management
Discontinue injection; administer oxygen, IV fluids, vasopressors; treat seizures with benzodiazepines; manage cardiac toxicity with lipid emulsion therapy.
⏰ Missed Dose
Not applicable; administered by healthcare professional.
🔄 Substitutes for bupicaine injection
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.