artether l 80 mg/480 mg tablet
What is artether l 80 mg/480 mg tablet used for?
Artether L (Artemether + Lumefantrine) is used to treat ANTI MALARIALS. It contains Artemether (80mg) + Lumefantrine (480mg), which Artemether: Produces free radicals damaging parasite membranes; Lumefantrine: In. Always consult your doctor before use. Take as prescribed.
- Generic Name: Artemether + Lumefantrine
- Manufacturer: Medley Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ artether l 80 mg/480 mg tablet Uses & Benefits
Uncomplicated falciparum malaria, chloroquine-resistant malaria.
Off-label uses: Severe malaria (IV artemether not available), babesiosis.
๐ Drug Information
| Generic Name(s) | Artemether + Lumefantrine |
| Brand Name | Artether L |
| Manufacturer | Medley Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI MALARIALS |
| Action Class | Antimalarial |
| Route of Administration | Oral |
| Storage | Store at 25ยฐC (77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Artemether: Produces free radicals damaging parasite membranes; Lumefantrine: Inhibits heme polymerization.
Mechanism Steps
๐ก How to Take artether l 80 mg/480 mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of artether l 80 mg/480 mg tablet
โ Common Side Effects
- Headache
- Dizziness
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
๐จ Serious Side Effects
- QT prolongation
- Cardiac arrhythmias
- Severe allergic reactions
- Hemolytic anemia (G6PD deficiency)
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Nephrotoxicity
- Neurotoxicity (high doses)
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Rifampin | Major | Reduced artemether/lumefantrine efficacy |
| Ketoconazole | Major | Increased lumefantrine levels, risk of QT prolongation |
| Amiodarone | Major | Additive QT prolongation |
| Oral contraceptives | Moderate | Reduced contraceptive efficacy |
| Antacids | Minor | Decreased absorption |
๐จ Major Interactions
- CYP3A4 inducers (rifampin, carbamazepine)
- CYP3A4 inhibitors (ketoconazole, ritonavir)
- Antiarrhythmics (amiodarone, quinidine)
โก Moderate Interactions
- Oral contraceptives
- Antipsychotics
- Macrolide antibiotics
โน๏ธ Minor Interactions
- Antacids
- H2 antagonists
๐ฝ๏ธ Food Interactions
Enhanced absorption with fatty foods; avoid grapefruit juice.
๐ท Alcohol Interaction
No significant interaction reported.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, severe hepatic impairment, known QT prolongation, concomitant with CYP3A4 inducers.
๐ Monitoring Parameters
ECG (QT interval), parasitemia, liver function tests.
๐คฑ Lactation Safety
Excreted in breast milk; caution advised.
๐ Overdose Management
Symptomatic and supportive; monitor ECG for QT prolongation.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip and resume schedule.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Found this to be a helpful product. Good results.
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.