Lumerax 80 Tablet (Artemether 80mg + Lumefantrine 480mg): Complete Guide
When to Call Your Doctor IMMEDIATELY
- Fainting or loss of consciousness
- Fast, irregular, or pounding heartbeat
- Severe dizziness or lightheadedness
- Difficulty breathing or swelling of the face, lips, or throat
- Yellowing of the eyes or skin, or dark urine
- Severe abdominal pain or persistent vomiting
- Blood in vomit or stool
- Seizures or confusion
- Unusual bleeding or bruising
- Signs of severe allergic reaction such as a widespread rash with blisters
If experiencing severe symptoms, call emergency services immediately.
What is Falcyrid 80 mg/480 mg Tablet used for?
This medicine is a combination antimalarial tablet containing artemether 80 mg and lumefantrine 480 mg. It is used to treat acute uncomplicated Plasmodium falciparum malaria in adults and children weighing 35 kg or more. It works by killing the malaria parasites in the blood. It must be taken with fatty food or milk for best absorption, and the full 3-day course must be completed.
- Generic Name: Artemether (80mg) + Lumefantrine (480mg)
- Manufacturer: Prayas Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Falcyrid 80 mg/480 mg Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा आर्टेमेथर और लुमेफैंट्रिन का संयोजन है, जिसका उपयोग मलेरिया (प्लास्मोडियम फाल्सीपेरम) के इलाज के लिए किया जाता है। यह मलेरिया परजीवी को खत्म करने में मदद करती है और बुखार, ठंड लगना और शरीर दर्द जैसे लक्षणों को जल्दी ठीक करती है। यह दवा उन वयस्कों और बच्चों के लिए है जिनका वजन 35 किलोग्राम या अधिक है। इसे भोजन के साथ या दूध के साथ लेना चाहिए ताकि यह अच्छी तरह से अवशोषित हो सके। यह दवा मलेरिया से बचाव के लिए नहीं है, बल्कि केवल इलाज के लिए है। इसे डॉक्टर के निर्देशानुसार पूरा कोर्स करना जरूरी है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में सिरदर्द, चक्कर आना, भूख न लगना, जी मिचलाना, उल्टी, पेट दर्द, दिल की धड़कन तेज होना, नींद में गड़बड़ी और हल्के दाने शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। कभी-कभी दिल की धड़कन धीमी हो सकती है या ईसीजी में क्यूटी इंटरवल बढ़ सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको सांस लेने में तकलीफ, चेहरे या गले में सूजन, बेहोशी, तेज या अनियमित दिल की धड़कन, या आंखों और त्वचा का पीला पड़ना दिखे, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे हमेशा भोजन या दूध के साथ लें, क्योंकि इससे दवा का असर बढ़ता है। गोली को पानी के साथ निगलें, चबाएं नहीं। पूरा 3 दिन का कोर्स पूरा करें, भले ही आपको पहले दिन में ही आराम महसूस होने लगे। इलाज के दौरान शराब न पिएं, क्योंकि इससे दिल की धड़कन और लीवर पर बुरा असर पड़ सकता है। अगर आपको दिल, लीवर या किडनी की कोई बीमारी है, या आप कोई अन्य दवा ले रहे हैं, तो डॉक्टर को जरूर बताएं। इस दवा को मलेरिया से बचाव के लिए न लें। इसे बच्चों की पहुंच से दूर रखें और सूखी, ठंडी जगह पर रखें।
💊 Falcyrid 80 mg/480 mg Tablet Uses & Benefits
- [{"condition":"Acute uncomplicated Plasmodium falciparum malaria","description":"This medicine is used to treat acute uncomplicated falciparum malaria in adults and children weighing 35 kg or more.
- It rapidly reduces parasite load and resolves fever.","evidence":"Well-established"},{"condition":"Mixed malaria infections including P.
- falciparum","description":"In areas where multiple Plasmodium species coexist, this medicine may be used when P.
- falciparum is confirmed or strongly suspected, often followed by primaquine for radical cure of P.
- vivax.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Malaria in pregnancy (second and third trimester)","description":"The World Health Organization recommends artemether-lumefantrine for uncomplicated falciparum malaria in the second and third trimesters of pregnancy, although it is not formally approved for this use in all countries.","evidence":"Moderate"},{"condition":"Intermittent preventive treatment in children","description":"Some studies have explored artemether-lumefantrine for intermittent preventive treatment in children in high-transmission areas, but this is not a standard recommendation.","evidence":"Limited"}]
Primary treatment for: Acute uncomplicated Plasmodium falciparum malaria
Also treats: Mixed malaria infections, Malaria in pregnancy (2nd and 3rd trimester)
📋 Drug Information
| Generic Name(s) | Artemether (80mg) + Lumefantrine (480mg) |
| Brand Name | Falcyrid 80 mg/480 mg Tablet |
| Manufacturer | Prayas Pharmaceuticals |
| Packaging / Form | strip of 4 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in the original packaging to protect from moisture and light. Do not refrigerate. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | The World Health Organization recommends artemether-lumefantrine as a first-line treatment for uncomplicated Plasmodium falciparum malaria in adults and children, including in the second and third trimesters of pregnancy. It is one of the preferred artemisinin-based combination therapies (ACTs) in endemic regions. |
| ICMR Guideline | The Indian Council of Medical Research (ICMR) recommends artemether-lumefantrine as a first-line treatment for uncomplicated Plasmodium falciparum malaria in India, in accordance with the National Drug Policy on Malaria. It is to be used with a 3-day course and taken with food. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antimalarial agents with complementary mechanisms. Artemether is converted in the body to dihydroartemisinin, which generates free radicals and alkylates parasite proteins, leading to rapid destruction of blood-stage malaria parasites. Lumefantrine interferes with the parasite's ability to detoxify heme, the toxic byproduct of hemoglobin digestion, causing accumulation of toxic heme and parasite death. Together, they provide rapid symptom relief and prevent recrudescence.
Mechanism Steps
💡 How to Take Falcyrid 80 mg/480 mg Tablet
Strength: Tablet containing artemether 80 mg and lumefantrine 480 mg.
Dosage Information
| Adult Dosage | The standard adult dose for uncomplicated Plasmodium falciparum malaria is a 3-day course. For adults weighing 35 kg or more, the usual regimen is 4 tablets (each containing artemether 80 mg and lumefantrine 480 mg) taken as a single dose at hour 0, followed by 4 tablets at hour 8, then 4 tablets twice daily (morning and evening) on days 2 and 3. This provides a total of 24 tablets over 3 days. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and local resistance patterns. Always take with fatty food or milk to enhance absorption. |
| Pediatric Dosage | This strength (80 mg artemether + 480 mg lumefantrine) is not recommended for children weighing less than 35 kg. For children weighing 35 kg or more, the adult dose may be used. For children weighing less than 35 kg, lower-strength pediatric formulations (e.g., 20 mg/120 mg) are available and should be dosed according to body weight. Pediatric dosing must be determined by a qualified pediatrician based on weight and clinical status. |
| Elderly Dosage | No specific dose adjustment is recommended for elderly patients based on age alone. However, elderly patients may have reduced hepatic or renal function and are more likely to have cardiac disease or take other medications. Use with caution and monitor for adverse effects, especially QT prolongation. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No dose adjustment is typically required for mild to moderate renal impairment. In severe renal impairment (creatinine clearance <30 mL/min), use with caution as data are limited. Monitor for adverse effects. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No dose adjustment is recommended for mild to moderate hepatic impairment. In severe hepatic impairment, use with caution as data are limited. Monitor liver function tests. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose for adults is 4 tablets (80 mg artemether + 480 mg lumefantrine per tablet) twice daily on days 2 and 3, and 4 tablets at hour 0 and hour 8 on day 1. Do not exceed the prescribed course. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Falcyrid 80 mg/480 mg Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Amiodarone | Major | |
| Ketoconazole | Major | |
| Rifampicin | Major | |
| Warfarin | Major | |
| Antacids | Moderate | |
| Hormonal contraceptives | Moderate | |
| Metoclopramide | Moderate | |
| Beta-blockers | Moderate | |
| Paracetamol | Minor | |
| Oral rehydration salts | Minor |
🚨 Major Interactions
- Drugs that prolong QT interval (e.g., amiodarone, sotalol, quinidine, macrolide antibiotics, fluoroquinolones, antipsychotics)
- CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir, clarithromycin)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin, St. John's wort)
- Warfarin
⚡ Moderate Interactions
- Antacids containing aluminum or magnesium
- Hormonal contraceptives
- Metoclopramide
- Beta-blockers
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can increase the risk of heart rhythm disturbances (QT prolongation), worsen dizziness and drowsiness, and increase the risk of liver toxicity. It may also reduce the effectiveness of treatment and delay recovery from malaria.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to artemether, lumefantrine, or any component of the formulation","Severe malaria (e.g., cerebral malaria, severe anemia, respiratory distress)","First trimester of pregnancy (relative contraindication; use only if no safer alternative)","History of congenital QT prolongation or family history of sudden cardiac death","Concomitant use with drugs that significantly prolong QT interval","Severe hepatic impairment","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["Take with food to ensure adequate absorption; fasting may reduce efficacy.","Avoid in patients with known QT prolongation or risk factors for arrhythmias.","Use with caution in patients with liver or kidney disease.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use for malaria prevention.","Complete the full course as prescribed, even if symptoms improve.","If vomiting occurs within 1 hour of taking a dose, consult your doctor for a repeat dose.","Inform your doctor if you are taking any other medications, especially those affecting heart rhythm.","Not recommended for children weighing less than 35 kg in this strength; use appropriate pediatric formulations.","Avoid alcohol during treatment."]
🤱 Lactation Safety
Artemether and lumefantrine are excreted in small amounts in breast milk. The World Health Organization considers artemether-lumefantrine compatible with breastfeeding. However, consult your doctor before use if you are breastfeeding, as the benefits of treatment should be weighed against potential risks to the infant.
💊 Overdose Management
Overdose of this medicine may cause severe QT prolongation, cardiac arrhythmias, and bone marrow suppression. There is no specific antidote. Treatment should be supportive and symptomatic, including continuous ECG monitoring, correction of electrolyte imbalances, and management of arrhythmias. In case of overdose, seek immediate medical attention. Contact a poison control center if available.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, provided it is not almost time for your next dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, with food that contains fat, such as milk, yogurt, or a meal cooked with oil, because food improves absorption of lumefantrine. Swallow the tablet whole with water; do not crush or chew it unless your doctor advises otherwise. Do not skip doses, and complete the full course even if you feel better after the first few doses. Avoid alcohol while taking this medicine because it may increase the risk of heart rhythm problems and worsen dizziness. Inform your doctor if you have a history of heart problems, long QT syndrome, liver or kidney disease, or if you are taking any other medicines, especially those that affect heart rhythm. Do not use this medicine to prevent malaria; it is only for treatment. Keep this medicine out of the reach of children, and store it in its original packaging at room temperature, away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the cardiac effects of this medicine, such as QT prolongation, and may have reduced liver or kidney function. Use with caution and monitor for adverse effects. Dose adjustment is not typically required based on age alone, but individualization by a clinician is recommended. Ensure adequate hydration and nutrition during treatment.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before taking this medicine. This medicine is recommended for uncomplicated malaria in the second and third trimesters of pregnancy. If you are in the first trimester, your doctor will weigh the benefits and risks of treatment. Effective contraception is advised during treatment and for a short period after, as the medicine may interact with hormonal contraceptives. Consult your doctor for personalized advice.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, inform your surgeon and anesthesiologist that you are taking this medicine, as it may interact with other medications and affect heart rhythm. This medicine is not typically used in the immediate post-operative period unless necessary for malaria treatment. Your doctor will determine the appropriate timing and dose based on your clinical status.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. This medicine may cause dizziness or palpitations, which could affect your ability to undergo dental treatment safely. There are no direct interactions with local anesthetics, but your dentist may take precautions. If you need dental work, it is best to complete your malaria treatment first and recover fully.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness, fatigue, or palpitations. Avoid strenuous exercise or activities that require mental alertness until you know how the medicine affects you. Light activity such as walking is generally fine if you feel up to it, but rest is important for recovery from malaria. Consult your doctor before resuming intense exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, fatigue, or palpitations, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how the medicine affects you. You may need to take time off work to rest and recover from malaria. Inform your employer if you need sick leave. Most people can resume normal activities after completing treatment and recovering from the illness.
🛑 When to Stop This Medicine
You should complete the full 3-day course of this medicine as prescribed, even if you feel better. Do not stop early, as this can lead to recurrence of malaria and contribute to drug resistance. If you experience severe side effects such as fainting, irregular heartbeat, difficulty breathing, or signs of liver problems, stop taking the medicine and seek immediate medical attention. Always consult your doctor before stopping this medicine for any reason.
📅 Long-Term Use Effects
This medicine is typically used for a short 3-day course, so long-term effects are not a concern for most patients. However, repeated or prolonged use may increase the risk of cardiac effects such as QT prolongation and liver enzyme abnormalities. There is also a theoretical risk of selecting resistant parasites if the full course is not completed. Regular monitoring of liver function and ECG may be advised in patients with underlying conditions or those requiring repeated courses. Always consult your doctor before using this medicine for more than the prescribed duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Alternatives such as artesunate-amodiaquine or dihydroartemisinin-piperaquine may be used if this medicine is not suitable or available.
Evidence: Well-establishedHydration, antipyretics, and rest are important adjuncts to antimalarial treatment.
Evidence: Well-establishedUsing insecticide-treated nets and indoor residual spraying helps prevent malaria.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, if you are due for a vaccine, inform your healthcare provider that you are taking this medicine. Live vaccines should generally be avoided during acute illness, including malaria. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially if traveling internationally, as this is a prescription medicine and customs may require documentation. Store it at room temperature and protect it from moisture and direct sunlight. If crossing time zones, continue taking the medicine according to the prescribed schedule; you may need to adjust the timing gradually. Do not pack it in checked luggage; keep it in your carry-on bag. If you are traveling to a malaria-endemic area, consult a travel medicine specialist about prevention, as this medicine is not for prevention.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within hours, and fever typically subsides within 24 to 48 hours. However, you must complete the full 3-day course to ensure all parasites are cleared.
A: No, this medicine should be taken with fatty food or milk to ensure proper absorption. Taking it on an empty stomach reduces its effectiveness.
A: If you miss a dose, take it as soon as you remember if it is not almost time for your next dose. If it is almost time, skip the missed dose and continue with your regular schedule. Do not double dose.
A: The World Health Organization recommends this medicine for uncomplicated malaria in the second and third trimesters of pregnancy. Use in the first trimester should be based on a risk-benefit assessment by your doctor.
A: No, alcohol should be avoided as it can increase the risk of heart rhythm problems, dizziness, and liver toxicity.
A: No, this medicine is only for treating confirmed or suspected malaria. It is not for prevention. Consult your doctor for preventive medications if you are traveling to a malaria-endemic area.
A: Seek immediate medical attention if you experience fainting, fast or irregular heartbeat, difficulty breathing, swelling of the face or throat, yellowing of the eyes or skin, or severe skin rash.
A: Store at room temperature between 15°C and 30°C, away from moisture and direct sunlight. Keep in the original packaging and out of reach of children.
🤔 Common Patient Concerns
🔄 Substitutes for Falcyrid 80 mg/480 mg Tablet
View AllAlternative brands with exact same active ingredient:
-
lumex forte 80 mg/480 mg tabletLeo Life Science Pvt Ltd ₹64.28 8.1% COSTLIER
-
Thereco 80mg/480mg TabletReco Drugs ₹70.31 18.2% COSTLIER
-
macito-lf 80mg/480mg tabletUnikind Pharma ₹77.50 30.3% COSTLIER
-
Tartlum 80mg/480mg TabletTusker Pharma Pvt Ltd ₹82.01 37.9% COSTLIER
-
endomal l 80 mg/480 mg tablet dtAlmet Corporation Ltd ₹84.54 42.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used to prevent malaria.
Fact: This medicine is only for treating confirmed or suspected malaria, not for prevention. Preventive treatment requires different medications. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full 3-day course to ensure all parasites are killed and to prevent recurrence and resistance. - Myth: It is safe to take on an empty stomach.
Fact: This medicine must be taken with fatty food or milk to ensure proper absorption. Taking it on an empty stomach reduces its effectiveness. - Myth: This medicine is safe for everyone.
Fact: It is not recommended for children under 35 kg in this strength, and it should be used with caution in people with heart, liver, or kidney problems. - Myth: Alcohol does not interact with this medicine.
Fact: Alcohol can increase the risk of heart rhythm problems and liver toxicity, and should be avoided during treatment.
🔄 Alternative Options
Generic Alternatives
- Artemether 80 mg + Lumefantrine 480 mg tablet (various manufacturers)
Brand Alternatives
- Lumerax 80 Tablet
- Coartem 80/480 Tablet
- Artemether/Lumefantrine 80/480 Tablet