cylip p 1.5 mg/55 mg drop - Cyproheptadine (1.5mg) + Tricholine Citrate (55mg) medicine

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🏭 Torque Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for appetite stimulation; limited for combination product.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe drowsiness or confusion
  • Seizures or convulsions
  • Yellowing of skin or eyes
  • Unusual bleeding or bruising
  • Persistent vomiting or severe abdominal pain
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is cylip p 1.5 mg/55 mg drop used for?

This medicine is a combination of cyproheptadine and tricholine citrate used to stimulate appetite and promote weight gain, especially in children. It works by blocking histamine and serotonin receptors in the brain, which increases hunger. It is available as oral drops and should be taken exactly as prescribed by a doctor.

  • Generic Name: Cyproheptadine + Tricholine Citrate
  • Manufacturer: Torque Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cylip p 1.5 mg/55 mg drop के बारे में (Hindi Summary)

उपयोग: यह दवा मुख्य रूप से भूख बढ़ाने और वजन बढ़ाने के लिए दी जाती है, खासकर बच्चों में। यह एलर्जी के लक्षणों जैसे छींक, नाक बहना और खुजली में भी राहत दे सकती है। यह साइप्रोहेप्टाडाइन और ट्राइकोलीन सिट्रेट का मिश्रण है। इसका सेवन डॉक्टर के निर्देशानुसार ही करें।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, मुँह सूखना, चक्कर आना और धुंधली दृष्टि शामिल हैं। कभी-कभी मतली, कब्ज या पेशाब में रुकावट हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर सांस लेने में तकलीफ, चेहरे पर सूजन, या पीलिया हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को लेने के बाद नींद आ सकती है, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब का सेवन न करें। नवजात शिशुओं को यह दवा न दें। डॉक्टर के बताए अनुसार ही खुराक लें। इसे बच्चों की पहुंच से दूर रखें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 cylip p 1.5 mg/55 mg drop Uses & Benefits

[{"condition":"Poor appetite and inadequate weight gain in children","description":"This medicine is commonly prescribed to stimulate appetite and support weight gain in children who are underweight or have poor oral intake.","evidence":"Commonly used in clinical practice; evidence from small studies and clinical experience."},{"condition":"Appetite loss associated with chronic illness or recovery","description":"May be used short-term to improve appetite after illness, surgery, or in chronic conditions where appetite is reduced.","evidence":"Limited evidence; often used based on clinical judgment."},{"condition":"Allergic conditions such as allergic rhinitis and urticaria","description":"Cyproheptadine, one of the ingredients, is an antihistamine that can relieve allergy symptoms like runny nose, sneezing, and itching.","evidence":"Well-established for cyproheptadine as a single agent."}]

Off-label uses: [{"condition":"Cyproheptadine for migraine prevention","description":"Sometimes prescribed off-label to prevent migraines, especially in children, due to its antiserotonin effects.","evidence":"Limited; some studies support use in pediatric migraine."},{"condition":"Cyproheptadine for serotonin syndrome","description":"Used off-label in emergency settings to counteract serotonin excess.","evidence":"Case reports and expert opinion."}]

Primary treatment for: Poor appetite and inadequate weight gain

Also treats: Allergic rhinitis, Urticaria, Appetite loss due to chronic illness

📋 Drug Information

Generic Name(s)Cyproheptadine + Tricholine Citrate
Brand NameAptimust Syrup
ManufacturerTorque Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassVITAMINS MINERALS NUTRIENTS
Action ClassAppetite Stimulant, Antihistamine, Hepatoprotective
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep the container tightly closed. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always measure the dose using the dropper provided; household spoons are not accurate.
2
Give this medicine with food to reduce stomach upset.
3
Avoid giving this medicine close to bedtime if it causes excessive drowsiness during the day.
4
Monitor weight gain and appetite regularly; if no improvement in 2-4 weeks, consult the doctor.
5
Do not use this medicine for longer than prescribed without medical review.
6
Inform your doctor if the child is taking any other medicines, especially for allergies or seizures.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Poor appetite
This medicine is commonly prescribed for this.
Likely Use
✅
Underweight
May be used to support weight gain.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Allergic rhinitis
Cyproheptadine component can help with allergy symptoms.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCyproheptadine is well absorbed from the gastrointestinal tract after oral administration. Tricholine citrate is also absorbed orally. Exact bioavailability data for the combination product is not established from the available information.
DistributionCyproheptadine is widely distributed in the body, including the central nervous system. It crosses the blood-brain barrier and placenta. Tricholine citrate distribution is not well characterized.
Protein BindingCyproheptadine is approximately 96% bound to plasma proteins. Tricholine citrate protein binding is not established from the available information.
MetabolismCyproheptadine undergoes extensive hepatic metabolism, primarily through glucuronidation and other phase II reactions. Tricholine citrate metabolism is not well established.
Half-LifeThe elimination half-life of cyproheptadine is approximately 8 to 12 hours. The half-life of tricholine citrate is not established from the available information.
ExcretionCyproheptadine and its metabolites are excreted mainly in urine and to a lesser extent in feces. Tricholine citrate excretion is not well characterized.
BioavailabilityNot established from the available information for the combination product.
Onset of ActionAppetite stimulation may begin within a few days of starting therapy, but full effect may take 1 to 2 weeks. Antihistamine effects occur within 1 to 2 hours.
Peak Plasma TimePeak plasma concentration of cyproheptadine is reached approximately 1 to 2 hours after oral administration. Tricholine citrate peak time is not established.
Duration of ActionThe sedative and antihistamine effects of cyproheptadine last about 4 to 8 hours. Appetite-stimulating effect persists with continued use.

How It Works

Cyproheptadine is a first-generation antihistamine that blocks histamine H1 receptors and serotonin 5-HT2 receptors. Blocking these receptors in the brain's appetite center leads to increased hunger. Tricholine citrate is a choline salt of trichloroacetic acid that may help emulsify fats and support liver function, though its exact contribution to appetite stimulation is not fully established.

Mechanism Steps

1
Histamine H1 receptor blockade: Cyproheptadine binds to H1 receptors in the brain and periphery, reducing allergic symptoms and causing sedation.
2
Serotonin 5-HT2 receptor blockade: Blockade of 5-HT2 receptors in the hypothalamus contributes to appetite stimulation.
3
Appetite center activation: The combined receptor blockade leads to increased hunger signals and improved food intake.
4
Tricholine citrate action: Tricholine citrate may enhance fat emulsification and support liver function, potentially improving digestion and nutrient absorption.

💡 How to Take cylip p 1.5 mg/55 mg drop

Strength: Oral drops: Cyproheptadine 1.5 mg + Tricholine Citrate 55 mg per dose (as per product label).

1Shake the bottle well before each use.
2Use the dropper provided to measure the exact dose prescribed.
3Administer directly into the mouth or mix with a small amount of water or juice if preferred.
4Take with food to reduce stomach upset.
5Follow the prescribed schedule consistently.
6Do not exceed the recommended dose.

Dosage Information

Adult DosageThe adult dose of this medicine is individualized by a qualified clinician based on the indication, age, weight, and liver function. A typical starting dose may be 2 to 5 mL (providing 1.5 mg to 3.75 mg cyproheptadine) two to three times daily, but this must be confirmed by your doctor. Do not self-adjust the dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. Doses are typically based on age and weight, and must be determined by a qualified clinician.
Elderly DosageElderly patients may be more sensitive to the sedative and anticholinergic effects of this medicine. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentDose adjustment may be needed in renal impairment. Consult a doctor for individualized dosing.
Hepatic ImpairmentUse with caution in hepatic impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum daily dose should not exceed the limit prescribed by your doctor. For adults, the maximum daily dose of cyproheptadine is generally 0.5 mg/kg/day, but this must be confirmed by a clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid large amounts
May increase drug levels.
Alcohol
Avoid
Increases sedation and drowsiness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of cylip p 1.5 mg/55 mg drop

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If persistent, consult your doctor.
Dry mouth (Common (5-15%))
Sip water, chew sugar-free gum, or use a saliva substitute. Consult doctor if severe.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid sudden movements.
Blurred vision (Uncommon (1-5%))
Usually temporary. Consult doctor if persistent.
Increased appetite (Common (desired effect))
This is the intended effect. Monitor weight gain as advised.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of face, lips, throat, difficulty breathing, or rash.
Blood disorders (e.g., agranulocytosis, hemolytic anemia) (Rare (<0.1%))
Report unusual bruising, bleeding, fever, or sore throat to your doctor immediately.
Liver problems (hepatotoxicity) (Rare (<0.1%))
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Seizures (Rare (<0.1%))
Seek emergency medical help if seizures occur.

⚠️ Rare Side Effects

Agranulocytosis
Hemolytic anemia
Thrombocytopenia
Hepatitis
Seizures
Photosensitivity

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
Alcohol Major
Benzodiazepines Major
Opioids Major
SSRIs Moderate
Tricyclic antidepressants Moderate
Beta-blockers Moderate
Levodopa Moderate
Antacids Minor
Grapefruit juice Minor

🚨 Major Interactions

  • MAO inhibitors
  • CNS depressants (e.g., alcohol, benzodiazepines, opioids)
  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)

⚡ Moderate Interactions

  • SSRIs
  • Beta-blockers
  • Levodopa

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and the risk of accidental injury. It may also worsen anticholinergic side effects such as dry mouth and blurred vision.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Newborns and premature infants","Narrow-angle glaucoma","Urinary retention","Severe liver disease","Hypersensitivity to any component","Concurrent use with MAO inhibitors"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in patients with asthma, increased intraocular pressure, hyperthyroidism, cardiovascular disease, or hypertension.","Do not exceed prescribed dose.","Not recommended for children under 2 years unless directed by a doctor.","May impair mental alertness in children; supervise activities."]

🤱 Lactation Safety

Cyproheptadine may pass into breast milk and could cause drowsiness in the infant. Consult a doctor before use during breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, confusion, hallucinations, seizures, and respiratory depression. Seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

This medicine can cause drowsiness, so avoid driving or operating heavy machinery until you know how it affects you. Do not give this medicine to newborns or premature infants. Do not drink alcohol while taking this medicine. Keep out of reach of children. Do not exceed the prescribed dose. Inform your doctor if you have glaucoma, asthma, urinary problems, or liver disease. Store in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to side effects like drowsiness, confusion, and urinary retention. Use with caution and lower doses may be needed. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy or are pregnant, consult your doctor before using this medicine. The safety profile in pregnancy is not well established. Use only if clearly needed.

🏥 Post-Surgery Considerations

After surgery, this medicine may be used to stimulate appetite during recovery. However, it can cause drowsiness and interact with anesthetic agents. Inform your surgeon and anesthesiologist about its use.

🦷 Dental Procedures

This medicine can cause dry mouth, which may increase the risk of dental caries. Maintain good oral hygiene and stay hydrated. Inform your dentist about its use before any dental procedure.

💚 Lifestyle Tips for Better Results

🏃
Offer small, frequent meals to stimulate appetite.
🥗
Include nutrient-dense foods like nuts, dairy, and eggs.
😴
Encourage physical activity to naturally boost appetite.
💧
Maintain a regular meal schedule.
🧘
Ensure adequate sleep and reduce stress.
🌞
Consult a dietitian for personalized advice.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. Light to moderate exercise is generally safe.

🥗 Diet Recommendations

Include protein-rich foods like lentils, eggs, and lean meat.
Add healthy fats such as ghee, nuts, and seeds.
Offer fruits and vegetables rich in vitamins.
Avoid junk food and sugary drinks that fill the stomach without nutrition.
Stay hydrated with water and fluids.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or perform tasks requiring focus. It is advisable to avoid such activities until you know how the medicine affects you. Children may need supervision during play or school activities.

🛑 When to Stop This Medicine

Stop taking this medicine only when your doctor advises. If you experience severe side effects or no improvement in appetite after the prescribed duration, consult your doctor. Do not stop abruptly without medical guidance.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance, dependence, and side effects such as weight gain, drowsiness, and anticholinergic effects. Regular monitoring of weight, liver function, and blood counts is advised. It should be used for the shortest duration necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary counseling

A dietitian can help create a calorie-dense meal plan to improve appetite and weight gain.

Evidence: Well-established
Behavioral therapy

For children with feeding difficulties, behavioral therapy can help establish healthy eating habits.

Evidence: Moderate
Treat underlying cause

Addressing conditions like anemia, thyroid disorders, or infections can improve appetite naturally.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if the child is unwell or has a fever, consult a doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case of customs checks. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust the dosing schedule gradually as advised by your doctor. Do not leave it in a hot car or checked luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 5-year-old child with poor appetite and underweight
The child was prescribed this medicine by a pediatrician. After 3 weeks of consistent use, the mother noticed the child eating better and gaining some weight. The child experienced mild drowsiness initially, which reduced after a few days. The doctor advised continuing for another month with regular monitoring.
💡 Lesson: Consistent use as prescribed and regular follow-up with the doctor are key to seeing results.
👤 An adult recovering from a prolonged illness with loss of appetite
An adult was given this medicine to help regain appetite after a severe infection. Within a week, appetite improved, and the patient was able to eat regular meals. The patient was advised not to drive due to drowsiness and to avoid alcohol.
💡 Lesson: This medicine can help adults too, but precautions like avoiding driving and alcohol are important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Appetite improvement may be noticed within a few days, but full effect may take 1 to 2 weeks of consistent use.

Q: Is it safe for children?

A: It is commonly used in children above 2 years, but only under a doctor's supervision. It is contraindicated in newborns.

Q: Can I stop taking it suddenly?

A: Do not stop without consulting your doctor. Sudden discontinuation may lead to rebound symptoms.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my child's growth?
  • Can I drive after taking this medicine?
  • Does it interact with other medicines?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for cylip p 1.5 mg/55 mg drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for any weight gain without a doctor's advice.
    Fact: It is a prescription medicine and should only be used under medical supervision.
  • Myth: It is safe to give to newborns for appetite.
    Fact: It is contraindicated in newborns and premature infants.
  • Myth: It has no side effects.
    Fact: It can cause drowsiness, dry mouth, and other side effects.

🔄 Alternative Options

Generic Alternatives

  • Cyproheptadine + Tricholine Citrate oral drops (generic)

Brand Alternatives

  • Cypon Oral Drops

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Cyproheptadine 1.5 mg + Tricholine Citrate 55 mg","form":"Oral drops","primary_use":"Appetite stimulation"},{"medicine":"Cyproheptadine alone","composition":"Cyproheptadine","form":"Tablet/Syrup","primary_use":"Allergy, appetite stimulation"},{"medicine":"Tricholine citrate alone","composition":"Tricholine citrate","form":"Syrup","primary_use":"Liver support, digestion"}]

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