arachitol 6l injection - Vitamin D3 (600000IU) medicine

Arachitol 6L Injection: Complete Guide to Uses, Dosage, and Safety

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🏭 Abbott 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for vitamin D deficiency.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: swelling of face, lips, throat, or difficulty breathing.
  • Signs of hypercalcemia: confusion, excessive thirst, frequent urination, nausea, vomiting.
  • Irregular heartbeat or palpitations.
  • Severe pain at injection site with redness and swelling.
  • Blood in urine or flank pain suggesting kidney stones.
  • Yellowing of skin or eyes (jaundice).
  • Persistent headache with visual changes.

If experiencing severe symptoms, call emergency services immediately.

What is arachitol 6l injection used for?

This medicine is a high-dose vitamin D3 injection used to treat severe vitamin D deficiency. It is given intramuscularly by a healthcare professional and helps restore vitamin D levels, improving bone and muscle health.

  • Generic Name: Cholecalciferol
  • Manufacturer: Abbott
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 arachitol 6l injection के बारे में (Hindi Summary)

उपयोग: यह दवा विटामिन डी3 का एक उच्च शक्ति वाला इंजेक्शन है, जिसका उपयोग गंभीर विटामिन डी की कमी को दूर करने के लिए किया जाता है। यह हड्डियों के दर्द, मांसपेशियों की कमजोरी और थकान को कम करने में मदद करती है। यह इंजेक्शन डॉक्टर द्वारा मांसपेशियों में लगाया जाता है और विटामिन डी के स्तर को तेजी से बढ़ाता है। यह उन लोगों के लिए है जिनमें विटामिन डी की कमी के कारण हड्डियों में दर्द या कमजोरी होती है। इसे बिना डॉक्टर की सलाह के नहीं लगवाना चाहिए।

साइड इफेक्ट्स: इस इंजेक्शन के सामान्य दुष्प्रभावों में इंजेक्शन वाली जगह पर दर्द या लालिमा, हल्की मतली, सिरदर्द और थकान शामिल हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको भ्रम, अत्यधिक प्यास, बार-बार पेशाब आना, या दिल की धड़कन अनियमित लगे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: यह इंजेक्शन केवल योग्य डॉक्टर या नर्स द्वारा ही लगाया जाना चाहिए। इसे स्वयं न लगाएं। अगर आपको किडनी की बीमारी, हृदय रोग, या सारकॉइडोसिस है तो डॉक्टर को बताएं। विटामिन डी की अन्य गोलियां या सप्लीमेंट्स बिना डॉक्टर की सलाह के न लें। डॉक्टर समय-समय पर कैल्शियम और विटामिन डी की जांच कर सकते हैं। पर्याप्त पानी पिएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 arachitol 6l injection Uses & Benefits

[{"condition":"Severe Vitamin D Deficiency","description":"Used to rapidly correct low vitamin D levels in individuals with symptoms such as bone pain, muscle weakness, and fatigue.","evidence":"Well-established"},{"condition":"Osteomalacia","description":"Helps in the treatment of soft bones due to vitamin D deficiency, improving bone mineralization and reducing pain.","evidence":"Well-established"},{"condition":"Rickets","description":"In children, used to treat vitamin D deficiency rickets, promoting proper bone growth and development.","evidence":"Well-established"},{"condition":"Hypocalcemia due to Vitamin D Deficiency","description":"Corrects low calcium levels that result from inadequate vitamin D, which is necessary for calcium absorption.","evidence":"Well-established"},{"condition":"Chronic Kidney Disease-Associated Vitamin D Deficiency","description":"May be used in patients with kidney disease who cannot convert vitamin D effectively, under close supervision.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Psoriasis","description":"Sometimes prescribed off-label for psoriasis due to vitamin D's role in skin cell regulation, but evidence is limited.","evidence":"Limited"},{"condition":"Multiple Sclerosis","description":"Vitamin D supplementation has been studied as a potential adjunct in multiple sclerosis, but high-dose injection is not standard.","evidence":"Limited"}]

Primary treatment for: Vitamin D Deficiency

Also treats: Osteomalacia, Rickets, Hypocalcemia, Chronic Kidney Disease

📋 Drug Information

Generic Name(s)Cholecalciferol
Brand NameArachitol 6L Injection
ManufacturerAbbott
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassVITAMINS MINERALS NUTRIENTS
Action ClassVitamins
Route of AdministrationIntramuscular (IM) injection. It should be administered by a healthcare professional into a large muscle such as the gluteal or deltoid muscle
StorageStore in a refrigerator at 2°C to 8°C. Do not freeze. Protect from light. Keep in the original carton until use. Bring to room temperature before injection if required.
Shelf Life24 months from the date of manufacture, unless otherwise specified on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always administer this injection in a healthcare setting; do not attempt self-injection.
2
Check serum calcium and vitamin D levels before and after administration to avoid toxicity.
3
Advise patients to maintain adequate calcium intake through diet, but avoid excessive supplements.
4
Caution patients with a history of kidney stones or hypercalcemia; consider alternative treatments.
5
Instruct patients to report symptoms of hypercalcemia such as confusion, thirst, or frequent urination immediately.
6
Use with caution in patients taking thiazide diuretics or digoxin; monitor closely.
7
Store the injection properly in a refrigerator and protect from light.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Bone pain
This medicine is used for severe vitamin D deficiency which can cause bone pain.
Likely Use
Muscle weakness
Vitamin D deficiency can lead to muscle weakness; this medicine helps correct it.
Likely Use
Fever
This medicine is not used to treat fever.
Not Primary
Common cold
This medicine is not indicated for colds.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFollowing intramuscular injection, cholecalciferol is absorbed slowly from the injection site into the systemic circulation. The absorption rate depends on blood flow to the muscle and the formulation. Peak plasma levels are typically reached within a few days to weeks, but this can vary.
DistributionCholecalciferol is highly lipophilic and is distributed primarily to the liver, adipose tissue, and other fat-rich tissues. It is stored in fat depots and released slowly over time. It crosses the placenta and is excreted in breast milk.
Protein BindingCholecalciferol and its metabolites are bound to vitamin D-binding protein (DBP) in the plasma, which facilitates their transport to target tissues.
MetabolismCholecalciferol is metabolized in the liver to 25-hydroxyvitamin D, which is the major circulating form. This is further metabolized in the kidneys to 1,25-dihydroxyvitamin D (calcitriol), the active form. Both metabolites undergo further hydroxylation and conjugation.
Half-LifeThe half-life of 25-hydroxyvitamin D is approximately 2-3 weeks, while calcitriol has a shorter half-life of about 4-6 hours. The injected cholecalciferol itself has a half-life of about 1-2 days.
ExcretionVitamin D metabolites are excreted primarily in bile and feces, with a small amount excreted in urine. Some metabolites undergo enterohepatic circulation.
BioavailabilityIntramuscular administration bypasses gastrointestinal absorption, providing high bioavailability, especially in patients with malabsorption. The exact bioavailability is not well established but is considered high.
Onset of ActionThe onset of action is gradual. Improvement in vitamin D levels can be seen within a few days, but clinical effects on bone and muscle may take several weeks to months.
Peak Plasma TimePeak plasma levels of 25-hydroxyvitamin D are typically reached 1-2 weeks after intramuscular injection, but this can vary based on individual factors.
Duration of ActionThe effects of a single 600,000 IU dose can last for several weeks to months, depending on the patient's baseline levels and metabolism. Repeat dosing is usually not done more frequently than every 3-6 months.

How It Works

This medicine delivers cholecalciferol, which is hydroxylated in the liver to 25-hydroxyvitamin D and then in the kidneys to 1,25-dihydroxyvitamin D (calcitriol), the biologically active form. Calcitriol binds to the vitamin D receptor (VDR) in target tissues, including the intestine, bone, and kidney, leading to increased calcium and phosphate absorption from the gut, mobilization of calcium from bone, and increased renal reabsorption of calcium. This results in normalization of calcium and phosphate levels, which are essential for bone mineralization and muscle function.

Mechanism Steps

1
Administration and Absorption: This medicine is injected intramuscularly, where it is absorbed into the bloodstream. The oily depot releases cholecalciferol gradually.
2
Liver Hydroxylation: Cholecalciferol is transported to the liver and converted to 25-hydroxyvitamin D by the enzyme CYP2R1.
3
Kidney Activation: In the kidneys, 25-hydroxyvitamin D is further hydroxylated to 1,25-dihydroxyvitamin D (calcitriol) by CYP27B1, especially when needed.
4
Receptor Binding: Calcitriol binds to the vitamin D receptor (VDR) in target cells, forming a complex that enters the nucleus and regulates gene expression.
5
Physiological Effects: This leads to increased calcium absorption in the intestine, calcium reabsorption in the kidney, and bone mineralization, correcting deficiency.

💡 How to Take arachitol 6l injection

Strength: 600,000 IU per injection (typically in a 1 mL ampoule or vial).

1This medicine is given by a healthcare professional as an intramuscular injection.
2You do not need to do anything to prepare for the injection, but inform your doctor of any allergies or medications you are taking.
3The injection is usually given in the upper outer quadrant of the buttock or the deltoid muscle.
4After the injection, you may experience some pain or soreness at the site; this is normal.
5Follow up with your doctor for blood tests to monitor your vitamin D levels.

Dosage Information

Adult DosageThe typical adult dose is 600,000 IU given as a single intramuscular injection. This dose may be repeated after 3 to 6 months if vitamin D levels remain low, as determined by your doctor. The dose must be individualized by a qualified clinician based on the severity of deficiency, age, weight, renal and hepatic function, and response to treatment. Do not self-administer; this injection should only be given by a healthcare professional.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the effects of vitamin D and are at higher risk of hypercalcemia. Dose should be individualized by a clinician, and calcium levels should be monitored closely.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary, and calcium and phosphate levels should be monitored. In severe renal impairment, alternative forms of vitamin D may be preferred.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment, but liver function should be monitored as vitamin D metabolism may be affected.
Maximum Daily DoseNot applicable for this formulation, as it is given as a single high-dose injection. The maximum cumulative dose should not exceed what is prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Calcium-rich foods (milk, yogurt, leafy greens)
Include in diet
Calcium is essential for bone health and works with vitamin D.
Grapefruit
No restriction
No known interaction with vitamin D.

⏰ What to Do If You Miss a Dose

📌 You miss your scheduled injection appointment.
→ Contact your doctor to reschedule as soon as possible.
💡 Do not attempt to self-administer or double the dose.
📌 You forget to follow up for a repeat dose.
→ Consult your doctor to determine if a repeat dose is needed based on blood tests.
💡 Do not take extra doses without medical advice.

⚠️ Side Effects of arachitol 6l injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Apply a cold compress to the area. It usually resolves within a day or two.
Nausea (Uncommon (1-5%))
Take small sips of water and avoid heavy meals. If it persists, consult your doctor.
Headache (Uncommon (1-5%))
Rest and stay hydrated. Consult your doctor if it is severe or persistent.
Fatigue (Uncommon (1-5%))
Ensure adequate rest. If fatigue is overwhelming, contact your doctor.

🚨 Serious Side Effects

Hypercalcemia (Rare (<0.1%))
Seek immediate medical attention if you experience confusion, excessive thirst, frequent urination, or irregular heartbeat.
Nephrocalcinosis (Rare (<0.1%))
Report any flank pain or blood in urine to your doctor immediately.
Severe allergic reaction (Very rare (<0.01%))
Call emergency services if you have difficulty breathing, swelling of face or throat, or a severe rash.

⚠️ Rare Side Effects

Vitamin D toxicity
Requires immediate medical attention. Symptoms include nausea, vomiting, and kidney problems.
Arrhythmias due to hypercalcemia
Seek emergency care if you feel palpitations or chest pain.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Thiazide diuretics Major
Digoxin Major
Calcium supplements Major
Corticosteroids Moderate
Orlistat Moderate
Cholestyramine Moderate
Aluminum-containing antacids Minor
Mineral oil Minor

🚨 Major Interactions

  • Thiazide diuretics
  • Digoxin
  • Calcium supplements

⚡ Moderate Interactions

  • Corticosteroids
  • Orlistat
  • Cholestyramine

🍷 Alcohol Interaction

Alcohol may impair vitamin D metabolism and increase the risk of bone loss. It is advisable to limit alcohol consumption while receiving this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypercalcemia","Hypervitaminosis D","Severe renal impairment","Known hypersensitivity to vitamin D or any component of the formulation","Sarcoidosis (may increase sensitivity to vitamin D)"]

⚠️ Warnings & Precautions

["Administer only under medical supervision.","Avoid concurrent use with other vitamin D supplements unless prescribed.","Monitor calcium levels regularly, especially in patients with kidney disease or those on thiazide diuretics.","Use with caution in patients with heart disease or arrhythmias.","Not for intravenous administration; for intramuscular use only.","Do not use if the solution is discolored or contains particles."]

🤱 Lactation Safety

Vitamin D is excreted in breast milk. High-dose injections may affect the infant, so use with caution and only under medical supervision. Breastfeeding mothers should consult their doctor.

💊 Overdose Management

Overdose can cause hypercalcemia, hypercalciuria, and hyperphosphatemia. Treatment is symptomatic and supportive. Stop the medicine and any calcium supplements. Hydrate the patient, and if necessary, use loop diuretics, corticosteroids, or calcitonin to lower calcium levels. In severe cases, hemodialysis may be required. Contact a poison control center or emergency services immediately.

⏰ Missed Dose

This medicine is usually given as a single dose or at intervals determined by your doctor. If you miss a scheduled appointment for your injection, contact your doctor to reschedule. Do not attempt to self-administer. If you miss a dose, do not double the next dose.

Additional Safety Advice

General Safety

This medicine should only be administered by a qualified healthcare professional. Do not attempt to self-inject. Inform your doctor if you have a history of kidney stones, heart disease, or sarcoidosis, as these conditions may increase the risk of high calcium levels. Avoid taking additional vitamin D supplements without your doctor's approval, as this can lead to toxicity. Your doctor may monitor your blood calcium and vitamin D levels periodically. Drink plenty of water to help prevent kidney stones. If you are pregnant or breastfeeding, consult your doctor before receiving this injection. Do not drive or operate heavy machinery if you feel dizzy or unwell after the injection.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of vitamin D deficiency and may be more susceptible to hypercalcemia. Close monitoring of calcium and vitamin D levels is advised. Dose should be individualized.

🤰 Pregnancy Planning (TTC)

Vitamin D is important for fertility and fetal development. If you are planning pregnancy, consult your doctor to check your vitamin D levels. High-dose injections should only be used if prescribed. Adequate vitamin D levels are associated with better pregnancy outcomes.

🏥 Post-Surgery Considerations

If you have recently had surgery, inform your surgeon about this injection. Vitamin D is important for bone healing, but high doses should be used with caution, especially if you are immobilized or have kidney issues.

🦷 Dental Procedures

There are no specific precautions for dental procedures while on this medicine. However, inform your dentist about all medications you are taking.

💚 Lifestyle Tips for Better Results

🏃
Get regular sunlight exposure for 15-20 minutes a day.
🥗
Maintain a balanced diet rich in calcium and vitamin D.
😴
Engage in weight-bearing exercises to strengthen bones.
💧
Avoid smoking and limit alcohol consumption.
🧘
Stay hydrated to support kidney function.
🌞
Follow up regularly with your doctor for monitoring.

🏋️ Exercise Considerations

While receiving this medicine, you can continue normal physical activity as tolerated. However, if you have bone pain or muscle weakness, avoid high-impact exercises until your condition improves. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include dairy products like milk, yogurt, and cheese.
Eat fatty fish such as salmon and mackerel.
Consume fortified cereals and juices.
Include egg yolks and mushrooms.
Ensure adequate protein intake for bone health.

💼 Impact on Daily Work & Life

This medicine is given as a single injection and generally does not affect your ability to work or drive. However, if you experience dizziness or fatigue after the injection, avoid driving or operating heavy machinery until you feel better.

🛑 When to Stop This Medicine

Do not stop or change the dosing schedule without consulting your doctor. This medicine is usually given as a single dose or at intervals determined by your doctor. If you experience severe side effects, contact your doctor immediately; they will decide whether to discontinue treatment.

📅 Long-Term Use Effects

Long-term effects of this medicine depend on the dose and frequency. When used appropriately, it corrects deficiency and improves bone health. However, excessive or repeated high doses can lead to vitamin D toxicity, hypercalcemia, and kidney damage. Regular monitoring of calcium and vitamin D levels is recommended. Lifestyle changes and maintenance doses of oral vitamin D may be needed to sustain normal levels.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral vitamin D supplements

For mild to moderate deficiency, oral cholecalciferol or ergocalciferol can be effective.

Evidence: Well-established
Increased sun exposure

Safe sun exposure helps the body produce vitamin D naturally.

Evidence: Well-established
Dietary changes

Consuming vitamin D-rich foods can help maintain levels.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, inform your healthcare provider about this injection before receiving any vaccine.

📦 Storage Guide

✅ DO

Store in refrigerator at 2°C to 8°C.

❌ DON'T

Do not freeze.

✅ DO

Keep in original carton to protect from light.

❌ DON'T

Do not transfer to another container.

✅ DO

Check expiry date before use.

❌ DON'T

Do not use if expired or if solution is discolored.

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label. Keep it in a cool, refrigerated condition if possible; use a cooler bag with ice packs. Carry a copy of your prescription to show at customs if needed. If you require an injection during travel, arrange for administration at a clinic or hospital. Do not expose the injection to extreme temperatures.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 50-year-old woman with severe vitamin D deficiency and bone pain.
She had been experiencing widespread bone pain and muscle weakness for months. Blood tests revealed very low vitamin D levels. Her doctor prescribed this injection. Within two weeks, she noticed significant improvement in her pain and energy levels. She was advised to continue oral vitamin D supplements and calcium-rich diet.
💡 Lesson: High-dose injection can rapidly correct severe deficiency, but follow-up with oral supplements and lifestyle changes is essential for long-term health.
👤 A 65-year-old man with chronic kidney disease and vitamin D deficiency.
He received this injection under close supervision. His calcium levels were monitored regularly. He experienced mild nausea initially, which resolved. His vitamin D levels improved, but he required careful monitoring to avoid hypercalcemia.
💡 Lesson: Patients with kidney disease need close monitoring when receiving high-dose vitamin D injections to prevent complications.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Improvement in vitamin D levels can be seen within a few days, but clinical effects on bone and muscle may take several weeks.

Q: Can I take this injection at home?

A: No, this injection must be administered by a healthcare professional in a clinic or hospital setting.

Q: What are the signs of too much vitamin D?

A: Signs include nausea, vomiting, confusion, excessive thirst, frequent urination, and irregular heartbeat. Seek immediate medical attention if these occur.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this injection if I have kidney disease?
  • How long will the effects last?
  • Do I need to take calcium supplements with this injection?
  • Can I drive after receiving this injection?
  • Is it safe to take other vitamin D supplements?
  • What if I miss a dose?

🔄 Substitutes for arachitol 6l injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Vitamin D injections are better than oral supplements.
    Fact: Injections are reserved for severe deficiency or malabsorption; oral supplements are effective for most people.
  • Myth: You can take this injection without a doctor's prescription.
    Fact: This is a prescription medicine and must be administered by a healthcare professional.
  • Myth: More vitamin D is always better.
    Fact: Excessive vitamin D can cause toxicity and hypercalcemia, which can be dangerous.

🔄 Alternative Options

Generic Alternatives

  • Cholecalciferol injection 600,000 IU

Brand Alternatives

  • Arachitol 6L injection

📊 Comparison with Similar Medicines

[{"medicine":"Arachitol 6L injection","active_ingredient":"Vitamin D3 600,000 IU","route":"Intramuscular","frequency":"Single dose or every 3-6 months","notes":"For severe deficiency; requires medical supervision."},{"medicine":"Oral Vitamin D3 60,000 IU","active_ingredient":"Vitamin D3 60,000 IU","route":"Oral","frequency":"Once weekly","notes":"For moderate deficiency; can be self-administered."}]

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