actipar syrup - Piperazine (NA) medicine

actipar syrup - Uses, Price, Side Effects & Substitutes

No reviews yet
๐Ÿญ Torque Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is actipar syrup used for?

Actipar Syrup (Piperazine) is used to treat ANTI INFECTIVES. It contains Piperazine (NA), which Piperazine causes paralysis of the worm by blocking acetylcholine at the neuromu. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Piperazine
  • Manufacturer: Torque Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š actipar syrup Uses & Benefits

Treatment of ascariasis (roundworm) and enterobiasis (pinworm).

Off-label uses: Not commonly used off-label.

๐Ÿ“‹ Drug Information

Generic Name(s)Piperazine
Brand NameActipar Syrup
ManufacturerTorque Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAntiprotozoal agents
Route of AdministrationOral (syrup).
StorageStore at room temperature (15-30ยฐC), protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract.
DistributionDistributed throughout body tissues, including cerebrospinal fluid.
Protein BindingNot significantly bound to plasma proteins.
MetabolismPartially metabolized in the liver.
Half-LifeApproximately 2-4 hours.
ExcretionExcreted primarily in urine, both unchanged and as metabolites.
BioavailabilityNot well documented; likely high due to good absorption.
Onset of ActionWithin 2-4 hours after oral administration.
Peak Plasma Time1-2 hours after oral dose.
Duration of ActionApproximately 6-8 hours.

How It Works

Piperazine causes paralysis of the worm by blocking acetylcholine at the neuromuscular junction, leading to expulsion by peristalsis.

Mechanism Steps

1Piperazine binds to GABA receptors on nematode muscle.
2Increases chloride ion conductance, causing hyperpolarization.
3Results in flaccid paralysis of the worm.

๐Ÿ’ก How to Take actipar syrup

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of actipar syrup

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal cramps
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Seizures
  • Ataxia
  • Hypotonia
  • Visual disturbances

โš ๏ธ Rare Side Effects

  • Allergic reactions
  • Urticaria
  • Elevated liver enzymes

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Pyrantel pamoate Major Antagonistic effect; do not use together.
Levamisole Major Antagonistic effect; do not use together.
Neuromuscular blocking agents Moderate Additive neuromuscular blockade.
Anticholinesterases Moderate Reduced efficacy of piperazine.
Alcohol Minor Increased CNS depression.

๐Ÿšจ Major Interactions

  • Pyrantel pamoate
  • Levamisole

โšก Moderate Interactions

  • Neuromuscular blocking agents
  • Anticholinesterases

โ„น๏ธ Minor Interactions

  • Alcohol
  • CNS depressants

๐Ÿฝ๏ธ Food Interactions

No significant food interactions reported.

๐Ÿท Alcohol Interaction

Avoid alcohol as it may increase CNS side effects.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to piperazine; epilepsy; severe renal impairment.

๐Ÿ“Š Monitoring Parameters

Stool examination for ova/parasites; liver function tests if prolonged use.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution.

๐Ÿ’Š Overdose Management

Induce vomiting or gastric lavage; supportive care for CNS effects.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for actipar syrup

View All

Alternative brands with exact same active ingredient (Piperazine (NA)):

Medical Note: Always consult your doctor before switching medications.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory
SaathiMed App
SaathiMed App Consult doctors & order medicines faster
Install