Cydil Plus 55 mg/1.5 mg Drop: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe drowsiness or difficulty staying awake
- Confusion, agitation, or hallucinations
- Fast, irregular, or pounding heartbeat
- Difficulty breathing or swelling of the face, lips, tongue, or throat
- Seizures or loss of consciousness
- Inability to pass urine or severe lower abdominal pain
- Yellowing of the skin or eyes, dark urine, or severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is cydil plus 55 mg/1.5 mg drop used for?
This medicine is an oral drop combination of Choline 55 mg and Cyproheptadine 1.5 mg. It is used under medical supervision to stimulate appetite and support weight gain, and to relieve certain allergic symptoms. It commonly causes drowsiness and dry mouth, and it should not be used in newborns, premature infants, or people with narrow-angle glaucoma or bladder neck obstruction.
- Generic Name: Choline + Cyproheptadine
- Manufacturer: Psychotropics India Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cydil plus 55 mg/1.5 mg drop के बारे में (Hindi Summary)
उपयोग: यह दवा कोलीन 55 मिलीग्राम और साइप्रोहेप्टाडीन 1.5 मिलीग्राम का ओरल ड्रॉप कॉम्बिनेशन है। इसका इस्तेमाल डॉक्टर की सलाह पर भूख बढ़ाने, वजन बढ़ाने में सहायता और कुछ एलर्जी वाले लक्षणों जैसे छींक, खुजली और नाक बहना कम करने के लिए किया जाता है। साइप्रोहेप्टाडीन हिस्टामिन और सेरोटोनिन को ब्लॉक करता है, जिससे एलर्जी कम होती है और भूख बढ़ सकती है। कोलीन तंत्रिका तंत्र और कोशिकाओं के सामान्य कामकाज में सहायता करता है। यह दवा नवजात शिशुओं, समय से पहले जन्मे बच्चों, ग्लूकोमा, पेशाब की रुकावट या अस्थमा के तीव्र दौरे वाले मरीजों के लिए नहीं है। इसका सेवन डॉक्टर के बताए अनुसार ही करें और खुद से डोज न बढ़ाएं।
साइड इफेक्ट्स: इस दवा के आम साइड इफेक्ट्स में नींद आना, मुंह सूखना, चक्कर आना और भूख बढ़ना शामिल हैं। कुछ लोगों को धुंधला दिखना, कब्ज या पेशाब में रुकावट महसूस हो सकती है। ये आमतौर पर हल्के होते हैं और शरीर के सामान्य होने पर कम हो जाते हैं। गंभीर लेकिन दुर्लभ साइड इफेक्ट्स में बहुत ज्यादा नींद आना, भ्रम, दिल की धड़कन तेज या अनियमित होना, और एलर्जी की गंभीर प्रतिक्रिया शामिल हैं। अगर आपको सांस लेने में तकलीफ, चेहरे या गले में सूजन, या बहुत ज्यादा नींद आ रही है, तो तुरंत डॉक्टर से मिलें। इस दवा को लेते समय गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको पता न चल जाए कि यह आप पर कैसे असर करती है।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और ड्रॉपर से सही मात्रा नापें। अपनी मर्जी से डोज न बढ़ाएं। इस दवा के साथ शराब न लें, क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। अपने डॉक्टर को अपनी सभी दवाओं, सप्लीमेंट्स और हर्बल उत्पादों के बारे में बताएं। जब तक आपको पता न चले कि यह दवा आपको कैसे प्रभावित करती है, तब तक गाड़ी न चलाएं और मशीन न चलाएं। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। इस दवा को बच्चों की पहुंच से दूर रखें और लेबल पर बताए अनुसार ही स्टोर करें।
💊 cydil plus 55 mg/1.5 mg drop Uses & Benefits
[{"condition":"Appetite stimulation and weight gain support","description":"This medicine is commonly prescribed to help stimulate appetite and support weight gain in selected patients who have poor appetite or unintended weight loss, under medical supervision.","evidence":"Established for cyproheptadine as an appetite stimulant in specific clinical settings"},{"condition":"Allergic conditions","description":"The cyproheptadine component can help relieve symptoms of allergic rhinitis, urticaria, and other histamine-mediated allergic reactions.","evidence":"Well-established for cyproheptadine as a first-generation antihistamine"},{"condition":"Choline supplementation","description":"The choline component is included to support normal cholinergic neurotransmission and cellular membrane function in patients who may benefit from additional choline.","evidence":"Choline is an essential nutrient; supplementation evidence varies by clinical context"}]
Off-label uses: [{"condition":"Cyproheptadine for migraine prevention","description":"Cyproheptadine is sometimes used off-label to help prevent migraines, particularly in children and adolescents, because of its antiserotonergic effects.","evidence":"Limited, based on small studies and clinical experience"},{"condition":"Cyproheptadine for serotonin syndrome","description":"In emergency settings, cyproheptadine has been used off-label as an antidote for serotonin syndrome under close medical supervision.","evidence":"Limited, based on case reports and expert opinion"}]
Primary treatment for: Appetite stimulation and weight gain support in selected patients
Also treats: Allergic rhinitis, Urticaria, Other histamine-mediated allergic conditions
📋 Drug Information
| Generic Name(s) | Choline + Cyproheptadine |
| Brand Name | Aptirich Syrup |
| Manufacturer | Psychotropics India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | Appetite Stimulant, Antihistamine |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep the container tightly closed and out of the reach of children. Do not freeze unless the label specifically instructs otherwise. |
| Shelf Life | Not established from the available information for this specific product. Check the expiry date on the package and do not use after that date. |
| WHO Guideline | Not established from the available information for this specific fixed-dose combination. |
| ICMR Guideline | Not established from the available information for this specific fixed-dose combination. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different mechanisms. Cyproheptadine is a first-generation antihistamine that blocks histamine H1 receptors and also antagonizes serotonin 5-HT2 receptors. By blocking H1 receptors, it reduces allergic symptoms such as sneezing, itching, and runny nose, and it causes drowsiness because histamine signaling in the brain is involved in wakefulness. By blocking 5-HT2 receptors, it can affect appetite regulation and mood-related pathways, which is why it is used to stimulate appetite. Choline is a precursor for acetylcholine, a neurotransmitter involved in memory, muscle control, and many autonomic functions, and it also contributes to cell membrane structure and lipid transport. The combination is intended to provide both antihistamine and appetite-stimulating effects along with choline support, but the exact contribution of the choline component in this fixed-dose product is not fully established from available information.
Mechanism Steps
💡 How to Take cydil plus 55 mg/1.5 mg drop
Strength: Oral drops containing Choline 55 mg and Cyproheptadine 1.5 mg per dose unit.
Dosage Information
| Adult Dosage | The adult dose of this medicine must be individualized by a qualified clinician based on the indication, age, weight, liver function, kidney function, and response to treatment. Dosing for appetite stimulation or allergic conditions may differ, and the drop formulation requires careful measurement with the provided dropper. Do not self-adjust the dose. Follow the prescription exactly, and contact your doctor if you have questions or if symptoms do not improve as expected. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific fixed-dose combination. Consult a pediatrician for appropriate dosing and monitoring. This medicine should not be given to newborns or premature infants. |
| Elderly Dosage | Elderly patients may be more sensitive to the sedative and anticholinergic effects of this medicine. Dosing should be individualized by a qualified clinician, and lower doses may be considered. Close monitoring for drowsiness, confusion, falls, urinary retention, and constipation is recommended. |
| Renal Impairment | Dosing in patients with kidney disease is not established from available information for this specific fixed-dose combination. Use with caution and under medical supervision. A clinician may consider dose adjustment based on kidney function. |
| Hepatic Impairment | Dosing in patients with liver disease is not established from available information for this specific fixed-dose combination. Use with caution and under medical supervision. A clinician may consider dose adjustment based on liver function. |
| Maximum Daily Dose | Not established from the available information for this specific fixed-dose combination. The maximum daily dose must be determined by a qualified clinician based on the patient's age, weight, indication, and clinical status. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cydil plus 55 mg/1.5 mg drop
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Opioids | Major | |
| Benzodiazepines | Major | |
| SSRIs/SNRIs | Major | |
| Tramadol | Major | |
| Anticholinergics | Moderate | |
| Beta-agonists | Moderate | |
| Levodopa | Moderate | |
| Antacids | Minor | |
| Alcohol | Major |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Other central nervous system depressants (opioids, benzodiazepines, sleep medicines, alcohol)
- Other serotonergic medicines (SSRIs, SNRIs, triptans, tramadol, linezolid)
⚡ Moderate Interactions
- Anticholinergic medicines (e.g., atropine, some antidepressants, antipsychotics)
- Beta-agonists and other sympathomimetics
- Levodopa and dopamine agonists
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because both alcohol and cyproheptadine can cause drowsiness and impair coordination, judgment, and alertness. Combining them increases the risk of excessive sedation, falls, and accidents. Patients should not drive or operate machinery after consuming alcohol while on this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to cyproheptadine, choline, or any component of this medicine","Newborns and premature infants","Narrow-angle glaucoma","Bladder neck obstruction or symptomatic prostate enlargement","Acute asthma attack","Concurrent use with monoamine oxidase inhibitors (MAOIs)"]
⚠️ Warnings & Precautions
["This medicine may cause drowsiness; avoid driving and operating machinery until you know how it affects you.","Avoid alcohol and other central nervous system depressants while taking this medicine.","Use with caution in patients with liver or kidney disease.","Use with caution in elderly patients, who may be more sensitive to sedation and anticholinergic effects.","Children may experience paradoxical excitation or restlessness; monitor closely.","Do not use in newborns or premature infants.","Consult a doctor before use if pregnant, planning pregnancy, or breastfeeding.","Do not stop long-term use suddenly without medical advice."]
🤱 Lactation Safety
Not established from the available information for this specific fixed-dose combination. Cyproheptadine may pass into breast milk and could cause drowsiness or other effects in a breastfed infant. Breastfeeding mothers should consult a doctor before using this medicine.
💊 Overdose Management
Overdose of this medicine may cause severe drowsiness, confusion, agitation, fast heartbeat, hallucinations, seizures, or difficulty breathing. If overdose is suspected, seek emergency medical care immediately. Do not try to induce vomiting unless instructed by a medical professional. Treatment is supportive and may include monitoring of vital signs, airway management, and symptomatic care. Contact a poison control center or emergency services right away.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember if it is still close to the scheduled time. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure what to do, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, using the dropper provided to measure each dose accurately. Do not increase the dose on your own, even if you feel it is not working quickly enough. Avoid alcohol and other medicines that cause drowsiness while taking this medicine, because the sedative effects can add up. Tell your doctor about all other medicines, supplements, and herbal products you use, especially antidepressants, sedatives, opioid pain medicines, and medicines for allergies or sleep. Do not drive, operate machinery, or do activities requiring alertness until you know how this medicine affects you. Keep this medicine out of the reach of children and store it in its original container as directed on the label. If you are pregnant, planning pregnancy, or breastfeeding, speak with your doctor before using this medicine. Do not stop this medicine suddenly without medical advice, especially if you have been taking it regularly for a long time.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to experience drowsiness, confusion, dizziness, falls, urinary retention, and constipation from this medicine. Lower doses may be considered, and close monitoring is recommended. Elderly patients should avoid driving or operating machinery if they feel drowsy or unsteady.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, talk to your doctor before using this medicine. Safety data for this combination in pregnancy are limited. Your doctor can help weigh the benefits and risks and discuss alternative options if needed.
🏥 Post-Surgery Considerations
Not established from the available information for this specific fixed-dose combination. After surgery, inform your surgical and anesthesia team about all medicines you take, including this one, because it can add to sedation and interact with other medicines. Follow your doctor's instructions about when to resume this medicine.
🦷 Dental Procedures
Inform your dentist about this medicine before any dental procedure. Because it can cause drowsiness and dry mouth, your dentist may take precautions and may recommend adjustments around the procedure. Do not stop the medicine without your doctor's advice.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness, so avoid strenuous exercise or activities that require balance and alertness until you know how it affects you. If you feel dizzy or sleepy, stop exercising and rest. Ask your doctor before starting a new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine commonly causes drowsiness, which can affect your ability to drive, operate machinery, or perform tasks that require alertness. Avoid these activities until you know how the medicine affects you. If your work involves safety-sensitive tasks, discuss with your doctor whether adjustments are needed. Dry mouth and dizziness may also affect comfort during the workday.
🛑 When to Stop This Medicine
Do not stop this medicine without talking to your doctor, especially if you have been taking it regularly for a long time. Your doctor may recommend a gradual reduction to avoid withdrawal effects. If you experience serious side effects such as severe drowsiness, fast heartbeat, or allergic reactions, seek medical attention immediately and follow your doctor's advice about stopping.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to persistent drowsiness, weight gain, and anticholinergic effects such as dry mouth, constipation, and urinary hesitancy. Regular monitoring of weight, appetite, liver function, and kidney function may be needed depending on the patient's condition. Prolonged use should be reviewed periodically by a doctor to ensure the benefits continue to outweigh the risks. Do not stop long-term use suddenly without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A dietitian can help create a personalized plan to improve appetite and weight gain.
Evidence: Well-establishedAddressing underlying causes of poor appetite or weight loss, such as thyroid problems or gastrointestinal disorders, is essential.
Evidence: Well-establishedFor allergic symptoms, non-sedating antihistamines may be an alternative when appropriate.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information for this specific fixed-dose combination. There are no known vaccine interactions specific to this product. Follow your doctor's advice about routine vaccinations.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not store in extreme heat or freezing conditions unless the label says otherwise.
✅ DO
Keep the container tightly closed and in its original packaging.
❌ DON'T
Do not transfer the medicine to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet where moisture can affect the medicine.
✅ DO
Keep out of the reach of children.
❌ DON'T
Do not leave the dropper or bottle where children can access it.
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription in case customs or security officials ask for it. Store the bottle at room temperature and protect it from extreme heat, cold, and direct sunlight. If you are crossing time zones, ask your doctor whether you need to adjust the timing of your doses. Keep the medicine in your carry-on luggage rather than checked baggage, and make sure it is out of the reach of children during travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The onset of effects varies by person and indication. Some effects, such as drowsiness, may be noticed within 30 to 60 minutes, while appetite changes may take days to weeks. Follow your doctor's advice and attend follow-up visits.
A: Do not combine with other antihistamines or sedating medicines without asking your doctor, because the effects can add up and increase drowsiness.
A: Safety data are limited. Use this medicine during pregnancy only if your doctor recommends it after weighing the benefits and risks.
A: Do not stop suddenly if you have been taking it for a long time. Ask your doctor how to taper safely.
🤔 Common Patient Concerns
🔄 Substitutes for cydil plus 55 mg/1.5 mg drop
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a general tonic for everyone.
Fact: This medicine is a prescription combination with specific indications and should only be used under medical supervision. - Myth: More medicine means faster weight gain.
Fact: Increasing the dose without medical advice can cause serious side effects and does not guarantee faster results. - Myth: It is safe to drive after taking this medicine.
Fact: This medicine commonly causes drowsiness and can impair driving and operating machinery. - Myth: This medicine can be stopped suddenly without any problem.
Fact: Long-term use should be stopped gradually under medical advice to avoid withdrawal effects.
🔄 Alternative Options
Generic Alternatives
- Choline and cyproheptadine oral drops in the same strengths, if available from a licensed generic manufacturer
Brand Alternatives
- Cydil Plus 55 mg/1.5 mg Drop