Aptimust Oral Drops: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat
- Severe drowsiness or inability to wake up
- Seizures or convulsions
- Yellowing of skin or eyes
- Blood in vomit or stool
- Inability to pass urine
- Severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is hysin 1.5 mg/55 mg drop used for?
This medicine is a combination of cyproheptadine and tricholine citrate used to stimulate appetite and support weight gain, especially in children. It works by blocking histamine and serotonin receptors in the brain to increase hunger, while tricholine citrate supports digestion.
- Generic Name: Cyproheptadine (1.5mg) + Tricholine Citrate (55mg)
- Manufacturer: Dr. Johns Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 hysin 1.5 mg/55 mg drop के बारे में (Hindi Summary)
उपयोग: यह दवा साइप्रोहेप्टाडीन और ट्राइकोलीन सिट्रेट का मिश्रण है, जिसका उपयोग मुख्य रूप से भूख बढ़ाने और वजन बढ़ाने में मदद के लिए किया जाता है। यह बच्चों और कुछ बड़ों में भूख की कमी, बीमारी के बाद कमजोरी, और वजन न बढ़ने की समस्या में दी जाती है। यह दवा दिमाग में हिस्टामिन और सेरोटोनिन रिसेप्टर्स को ब्लॉक करके भूख बढ़ाती है और ट्राइकोलीन सिट्रेट पाचन और लिवर को सहारा देता है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुँह सूखना, चक्कर आना और पेट में हल्की गड़बड़ी शामिल हैं। कुछ बच्चों में नींद की जगह बेचैनी या चिड़चिड़ापन भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर सांस लेने में तकलीफ, चेहरे या गले में सूजन, या पीलिया जैसे लक्षण दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा का उपयोग केवल डॉक्टर की सलाह पर करें और बताई गई मात्रा से ज्यादा न दें। नवजात शिशुओं को यह दवा न दें। दवा लेने के बाद गाड़ी चलाने या मशीन चलाने से बचें क्योंकि इससे नींद आ सकती है। शराब का सेवन न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। दवा को बच्चों की पहुंच से दूर रखें।
💊 hysin 1.5 mg/55 mg drop Uses & Benefits
[{"condition":"Poor appetite and inadequate weight gain in children","description":"This medicine is commonly prescribed to stimulate appetite and support weight gain in children with poor oral intake or failure to thrive when other causes have been evaluated.","evidence":"Commonly used in clinical practice; evidence quality varies"},{"condition":"Appetite loss during recovery from illness","description":"It may be used short-term to improve appetite after infections, surgery, or other conditions that reduce food intake.","evidence":"Limited to moderate evidence"},{"condition":"Nausea and vomiting associated with certain conditions","description":"Cyproheptadine has antiemetic properties that can help reduce nausea in selected patients.","evidence":"Limited evidence"},{"condition":"Allergic conditions such as itching and urticaria","description":"The antihistamine component can relieve itching and allergic skin reactions, though this combination is not primarily marketed for allergy alone.","evidence":"Well-established for cyproheptadine"}]
Off-label uses: [{"condition":"Migraine prevention in children","description":"Cyproheptadine is sometimes used off-label to reduce migraine frequency in children and adolescents.","evidence":"Limited to moderate evidence"},{"condition":"Cyclic vomiting syndrome","description":"It may be used off-label to reduce episodes of cyclic vomiting in some patients.","evidence":"Limited evidence"},{"condition":"Insomnia related to serotonin syndrome","description":"Cyproheptadine has been used off-label in specialized settings for serotonin syndrome, but this is not a routine use of this combination product.","evidence":"Case reports and expert opinion"}]
Primary treatment for: Poor appetite and inadequate weight gain
Also treats: Appetite loss during recovery, Nausea and vomiting, Allergic itching
📋 Drug Information
| Generic Name(s) | Cyproheptadine (1.5mg) + Tricholine Citrate (55mg) |
| Brand Name | hysin 1.5 mg/55 mg drop |
| Manufacturer | Dr. Johns Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Keep the bottle tightly closed. |
| Shelf Life | Refer to the packaging for the exact shelf life. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different actions. Cyproheptadine is a first-generation antihistamine that blocks histamine H1 receptors and also antagonizes serotonin 5-HT2 receptors. This dual action reduces allergic symptoms and nausea, and it stimulates appetite through effects on appetite-regulating pathways in the brain. Tricholine citrate is a bile acid sequestrant that binds bile acids in the intestine, which may alter fat digestion and support liver function. The appetite-stimulating effect is mainly attributed to cyproheptadine, while tricholine citrate is included to support digestive and hepatic health.
Mechanism Steps
💡 How to Take hysin 1.5 mg/55 mg drop
Strength: Oral drops containing Cyproheptadine 1.5 mg and Tricholine Citrate 55 mg per dose unit.
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the indication, age, weight, and liver and kidney function. For adults, it is typically prescribed as a small measured dose using the dropper provided, often once or twice daily. Do not self-adjust the dose. Follow your doctor's instructions exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the sedative and anticholinergic effects of this medicine. Use with caution and lower doses may be advised by the doctor. |
| Renal Impairment | Dose adjustment may be needed in patients with kidney disease. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with liver disease. Dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information. Follow your doctor's prescription. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of hysin 1.5 mg/55 mg drop
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAO inhibitors | Major | |
| CNS depressants | Major | |
| Anticholinergics | Major | |
| SSRIs | Moderate | |
| Beta-blockers | Moderate | |
| Diuretics | Moderate | |
| Antacids | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- MAO inhibitors
- CNS depressants (e.g., benzodiazepines, opioids, alcohol)
- Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
⚡ Moderate Interactions
- Selective serotonin reuptake inhibitors (SSRIs)
- Beta-blockers
- Diuretics
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can significantly increase drowsiness, dizziness, and impairment of judgment. Combining alcohol with cyproheptadine may also increase the risk of respiratory depression.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Newborns and premature infants","Narrow-angle glaucoma","Urinary retention or prostatic hypertrophy","Severe liver disease","Known hypersensitivity to cyproheptadine or tricholine citrate","Concurrent use with MAO inhibitors"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not use in newborns or premature infants.","Use with caution in elderly patients due to increased risk of confusion and falls.","Avoid alcohol and other CNS depressants.","Consult a doctor before use in pregnancy or breastfeeding.","Do not exceed the prescribed dose.","Keep out of reach of children."]
🤱 Lactation Safety
Cyproheptadine may pass into breast milk and could cause drowsiness in the infant. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause severe drowsiness, confusion, rapid heartbeat, hallucinations, and seizures. Seek emergency medical attention immediately. Treatment is supportive and symptomatic. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Use this medicine only when prescribed by a qualified doctor, and follow the exact dose and duration advised. Do not give this medicine to newborns or premature infants. Avoid driving, cycling, or operating heavy machinery until you know how this medicine affects your alertness. Do not drink alcohol while taking this medicine because it can increase drowsiness and impair judgment. Keep the bottle tightly closed and out of reach of children. Tell your doctor about all other medicines, especially sedatives, antidepressants, and anticholinergic drugs. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Do not use this medicine as a replacement for a healthy diet and regular meals.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to sedation, confusion, and falls. Use with caution and lower doses may be needed. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before using this medicine. The safety of this combination in pregnancy is not well established.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine after surgery, as it may interact with anesthetics and other medications.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it can cause dry mouth and may interact with sedatives used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring balance until you know how it affects you. Light to moderate exercise is generally safe.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. It is best to take it when you do not need to be alert. Discuss with your doctor if your work requires high concentration.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Your doctor will determine the appropriate duration based on your response and underlying condition. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine should be monitored by a doctor. Prolonged use of cyproheptadine may lead to tolerance of its sedative effects and potential weight gain beyond desired levels. Regular monitoring of weight, appetite, and liver function is advised. Do not use for extended periods without medical review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A nutritionist can help create a high-calorie, nutrient-rich diet plan.
Evidence: Well-establishedAddressing medical or psychological causes of poor appetite.
Evidence: Well-establishedMedicines like megestrol or dronabinol may be used in specific cases.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established from the available information. Continue routine vaccinations as scheduled.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case of customs checks. Store at room temperature and protect from extreme heat or cold. If crossing time zones, consult your doctor about adjusting the dosing schedule. Keep the bottle tightly closed and out of reach of children.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Appetite improvement may be noticed within a few days to weeks. Weight gain typically takes several weeks of consistent use.
A: It is commonly prescribed for children but should only be used under a doctor's supervision. It is not for newborns.
A: Do not stop without consulting your doctor. Your doctor will advise on the duration of treatment.
🤔 Common Patient Concerns
🔄 Substitutes for hysin 1.5 mg/55 mg drop
View AllAlternative brands with exact same active ingredient:
-
cylip p 1.5 mg/55 mg dropTorque Pharmaceuticals Pvt Ltd ₹15.00 40.7% CHEAPER
-
hepsandin 1.5mg/55mg dropSresan Pharmaceuticals ₹25.43 0.5% COSTLIER
-
aptimust oral dropsMankind Pharma Ltd ₹27.50 8.7% COSTLIER
-
apel g 1.5mg/55mg dropLancer Health Care Pvt Ltd ₹27.93 10.4% COSTLIER
-
aptivin 1.5 mg/55 mg dropDivine Lifecare Pvt Ltd ₹28.13 11.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used by anyone to gain weight quickly.
Fact: It is a prescription medicine and should only be used under medical supervision for specific indications. - Myth: It is safe to give to newborns.
Fact: It is contraindicated in newborns and premature infants. - Myth: It has no side effects.
Fact: It can cause drowsiness, dry mouth, and other side effects.
🔄 Alternative Options
Generic Alternatives
- Cyproheptadine + Tricholine Citrate oral drops
Brand Alternatives
- Aptimust Oral Drops