celtere 80mg injection - Uses, Price, Side Effects & Substitutes
What is celtere 80mg injection used for?
Adoxi 20mg Injection Combipack (Docetaxel) is used to treat ANTI NEOPLASTICS. It contains Docetaxel (80mg), which Promotes assembly of microtubules and inhibits their disassembly, leading to mit. Always consult your doctor before use. Take as prescribed.
- Generic Name: Docetaxel
- Manufacturer: Celon Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ celtere 80mg injection Uses & Benefits
Breast cancer, non-small cell lung cancer, prostate cancer, gastric cancer, head and neck cancer.
Off-label uses: Ovarian cancer, esophageal cancer, bladder cancer.
๐ Drug Information
| Generic Name(s) | Docetaxel |
| Brand Name | Adoxi 20mg Injection Combipack |
| Manufacturer | Celon Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimicrotubule agents- Taxanes |
| Route of Administration | Intravenous infusion. |
| Storage | Store at 2-8ยฐC; protect from light; do not freeze. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Promotes assembly of microtubules and inhibits their disassembly, leading to mitotic arrest and cell death.
Mechanism Steps
๐ก How to Take celtere 80mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of celtere 80mg injection
โ Common Side Effects
- Neutropenia
- Anemia
- Thrombocytopenia
- Alopecia
- Nausea
- Vomiting
- Diarrhea
- Fatigue
- Peripheral neuropathy
- Myalgia
๐จ Serious Side Effects
- Severe neutropenia with fever
- Hypersensitivity reactions
- Fluid retention
- Cardiotoxicity
- Hepatotoxicity
- Severe diarrhea
- Interstitial pneumonitis
โ ๏ธ Rare Side Effects
- Acute myeloid leukemia
- Severe skin reactions
- Capillary leak syndrome
- Pulmonary fibrosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased docetaxel toxicity |
| Rifampin | Major | Decreased docetaxel efficacy |
| Warfarin | Major | Increased bleeding risk |
| Clopidogrel | Moderate | Increased bleeding risk |
| Cisplatin | Moderate | Increased neuropathy risk |
| Doxorubicin | Moderate | Increased cardiotoxicity risk |
| Dexamethasone | Minor | Reduced docetaxel clearance |
| Diphenhydramine | Minor | Reduced docetaxel clearance |
| Grapefruit juice | Minor | Increased docetaxel exposure |
๐จ Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- CYP3A4 inducers (e.g., rifampin, carbamazepine)
- Warfarin
โก Moderate Interactions
- Clopidogrel
- Cisplatin
- Doxorubicin
โน๏ธ Minor Interactions
- Dexamethasone
- Diphenhydramine
๐ฝ๏ธ Food Interactions
Grapefruit juice (may increase exposure)
๐ท Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to docetaxel or polysorbate 80; severe hepatic impairment; neutropenia (<1500 cells/mmยณ); pregnancy.
๐ Monitoring Parameters
Complete blood count, liver function tests, renal function, vital signs, infusion reactions.
๐คฑ Lactation Safety
Contraindicated; excreted in breast milk.
๐ Overdose Management
Supportive care; monitor for myelosuppression, mucositis, and neuropathy.
โฐ Missed Dose
Do not double dose; contact physician for rescheduling.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for celtere 80mg injection
View AllAlternative brands with exact same active ingredient (Docetaxel (80mg)):
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Relidoce 80mg InjectionReliance Formulation Pvt Ltd โน1,400.00 85.1% CHEAPER
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docax 80mg injectionNeon Laboratories Ltd โน2,171.00 76.8% CHEAPER
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dc fill 80mg injectionFourrts India Laboratories Pvt Ltd โน2,203.13 76.5% CHEAPER
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chemodoc 80mg injectionLupin Ltd โน4,597.16 50.9% CHEAPER
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zenotere 80mg injectionSun Pharmaceutical Industries Ltd โน5,400.00 42.3% CHEAPER
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innotubilin 80mg injectionInnova Formulations Pvt Ltd โน5,475.00 41.5% CHEAPER
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doxel 80mg injectionShantha Biotech โน7,031.25 24.9% CHEAPER
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Taxewell 80mg InjectionGetwell Oncology Pvt Ltd โน7,631.25 18.5% CHEAPER
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doxaz 80mg injectionEmcure Pharmaceuticals Ltd โน8,035.71 14.2% CHEAPER
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zytax 80mg injectionZydus Cadila โน9,093.75 2.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.