Alkacel 50 Injection - Uses, Price, Side Effects
What is alkacel 50 injection used for?
Alkacel 50 Injection contains Melphalan 50mg, a chemotherapy drug used to treat multiple myeloma and ovarian cancer. It works by interfering with DNA replication in cancer cells, slowing their growth. It is administered intravenously under medical supervision.
- Generic Name: Melphalan
- Manufacturer: Celon Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ alkacel 50 injection Uses & Benefits
Multiple myeloma, ovarian cancer, breast cancer, malignant melanoma, soft tissue sarcoma.
Off-label uses: Amyloidosis, conditioning for stem cell transplant.
๐ Drug Information
| Generic Name(s) | Melphalan |
| Brand Name | Alphalan |
| Manufacturer | Celon Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Alkylating agent |
| Route of Administration | Oral, intravenous. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Alkylating agent; cross-links DNA, inhibiting DNA replication and transcription.
Mechanism Steps
๐ก How to Take alkacel 50 injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of alkacel 50 injection
โ Common Side Effects
- Nausea
- Vomiting
- Myelosuppression
- Alopecia
- Mucositis
๐จ Serious Side Effects
- Severe myelosuppression
- Secondary malignancies
- Pulmonary fibrosis
- Venocclusive disease
โ ๏ธ Rare Side Effects
- Anaphylaxis
- Hemolytic anemia
- Interstitial pneumonitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Live vaccines | Major | Risk of disseminated infection |
| NSAIDs | Moderate | Increased nephrotoxicity |
๐จ Major Interactions
- Cyclosporine
- Tacrolimus
- Other alkylating agents
- Radiation therapy
โก Moderate Interactions
- NSAIDs
- Anticoagulants
- Live vaccines
- Phenytoin
โน๏ธ Minor Interactions
- Cimetidine
- Allopurinol
๐ฝ๏ธ Food Interactions
Food may reduce absorption; take on empty stomach.
๐ท Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to melphalan, severe myelosuppression, pregnancy, breastfeeding.
๐ Monitoring Parameters
Complete blood count, renal function, hepatic function, serum uric acid.
๐คฑ Lactation Safety
Contraindicated; excreted in breast milk.
๐ Overdose Management
Supportive care; monitor blood counts; consider hematopoietic growth factors.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for alkacel 50 injection
View AllAlternative brands with exact same active ingredient (Melphalan (50mg)):
-
alphalan 50mg injectionNatco Pharma Ltd โน1,684.00 29.8% CHEAPER
-
melfalax 50mg injectionGLS Pharma Ltd. โน2,500.00 4.2% COSTLIER
-
megval 50mg injectionEmcure Pharmaceuticals Ltd โน2,597.00 8.2% COSTLIER
-
melphater 50mg injectionTherdose Pharma Pvt Ltd โน4,200.00 75% COSTLIER
Medical Note: Always consult your doctor before switching medications.