Taxotere 80mg Injection (Docetaxel): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Fever of 38°C or higher, chills, or shivering.
- Difficulty breathing, wheezing, or swelling of the face, lips, or throat.
- Severe mouth ulcers that make it hard to eat or drink.
- Unusual bleeding, bruising, or blood in vomit or stool.
- Chest pain, palpitations, or fainting.
- Yellowing of the eyes or skin, dark urine, or severe abdominal pain.
- Rapid weight gain, severe ankle swelling, or sudden breathlessness.
- New or worsening numbness, weakness, or balance problems.
- Severe skin rash, blistering, or peeling.
- Confusion, extreme tiredness, or inability to stay awake.
If experiencing severe symptoms, call emergency services immediately.
What is Relidoce 80mg Injection used for?
This medicine is an injectable chemotherapy medicine containing docetaxel. It is used to treat breast cancer, non-small cell lung cancer, prostate cancer, gastric cancer, and head and neck cancer. It works by blocking cancer cell division and is given by a healthcare professional as an intravenous infusion, usually every three weeks.
- Generic Name: Docetaxel (80mg)
- Manufacturer: Reliance Formulation Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Relidoce 80mg Injection के बारे में (Hindi Summary)
उपयोग: यह दवा डोसेटैक्सल नामक कीमोथेरेपी दवा है, जिसे इंजेक्शन के रूप में नस के माध्यम से दिया जाता है। इसका उपयोग मुख्य रूप से स्तन कैंसर, फेफड़ों के कैंसर, प्रोस्टेट कैंसर, पेट के कैंसर और सिर तथा गर्दन के कैंसर के इलाज में किया जाता है। यह कैंसर कोशिकाओं के विभाजन को रोककर उन्हें नष्ट करने में मदद करती है। यह दवा केवल कैंसर रोग विशेषज्ञ या प्रशिक्षित स्वास्थ्यकर्मी द्वारा अस्पताल या कीमोथेरेपी सेंटर में ही दी जाती है। इसे घर पर स्वयं नहीं लगाया जाना चाहिए। इलाज के दौरान खून की जांच, लीवर की जांच और डॉक्टर की निगरानी बहुत जरूरी होती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में बाल झड़ना, थकान, जी मिचलाना, उल्टी, मुंह में छाले, भूख कम लगना, मांसपेशियों और जोड़ों में दर्द, हाथ-पैरों में झनझनाहट, त्वचा पर दाने और पैरों में सूजन शामिल हैं। गंभीर दुष्प्रभावों में खून की कोशिकाओं का बहुत कम हो जाना, बुखार के साथ संक्रमण, तेज एलर्जी, सांस लेने में कठिनाई, गंभीर त्वचा प्रतिक्रियाएं और लीवर की समस्या शामिल हो सकती हैं। अगर बुखार, ठंड लगना, सांस फूलना, अचानक सूजन या गंभीर कमजोरी महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल अस्पताल या कीमोथेरेपी सेंटर में प्रशिक्षित डॉक्टर या नर्स द्वारा ही दी जानी चाहिए। इसे घर पर स्वयं न लगाएं। इलाज के दौरान गर्भधारण से बचें और स्तनपान न कराएं। अपने डॉक्टर को अपनी सभी दवाओं, विटामिन और हर्बल उत्पादों के बारे में बताएं। बुखार, ठंड लगना, गले में दर्द, मुंह के छाले, असामान्य रक्तस्राव, सांस फूलना या अचानक वजन बढ़ना जैसी समस्याएं तुरंत बताएं। इलाज के दौरान पर्याप्त आराम करें और डॉक्टर के बताए अनुसार पानी पिएं।
💊 Relidoce 80mg Injection Uses & Benefits
[{"condition":"Breast cancer","description":"Used as adjuvant, neoadjuvant, or metastatic treatment, often in combination with other chemotherapy agents or targeted therapy.","evidence":"Well-established"},{"condition":"Non-small cell lung cancer","description":"Used as first-line or later-line therapy, usually in platinum-based combinations for advanced disease.","evidence":"Well-established"},{"condition":"Hormone-refractory prostate cancer","description":"Used with prednisone or prednisolone to improve survival and pain control in metastatic castration-resistant disease.","evidence":"Well-established"},{"condition":"Gastric adenocarcinoma","description":"Used in combination regimens for advanced or metastatic stomach cancer.","evidence":"Established"},{"condition":"Squamous cell carcinoma of head and neck","description":"Used in induction or palliative combination chemotherapy for locally advanced or recurrent disease.","evidence":"Established"}]
Off-label uses: [{"condition":"Ovarian cancer","description":"Sometimes used in platinum-resistant or recurrent ovarian cancer when other options are limited.","evidence":"Limited"},{"condition":"Bladder cancer","description":"Occasionally used in combination regimens for advanced urothelial cancer.","evidence":"Limited"},{"condition":"Soft tissue sarcoma","description":"Used in selected patients with advanced soft tissue sarcoma in specialist centres.","evidence":"Limited"}]
Primary treatment for: Breast cancer
Also treats: Non-small cell lung cancer, Hormone-refractory prostate cancer, Gastric adenocarcinoma, Squamous cell carcinoma of head and neck
📋 Drug Information
| Generic Name(s) | Docetaxel (80mg) |
| Brand Name | Relidoce 80mg Injection |
| Manufacturer | Reliance Formulation Pvt Ltd |
| Packaging / Form | vial of 2 ml Injection (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Parenteral (intravenous infusion) |
| Storage | Store the unopened vial in a refrigerator between 2°C and 8°C, protected from light. Do not freeze. After dilution, the infusion solution should be used as soon as possible and according to the instructions provided by your pharmacist or oncology team. |
| Shelf Life | The shelf life of the unopened vial is usually 24 months from the date of manufacture, but always check the expiry date printed on the vial and follow the storage instructions provided by the manufacturer and pharmacy. |
| WHO Guideline | Docetaxel is included in several World Health Organization essential medicines lists and cancer treatment guidelines for breast cancer, non-small cell lung cancer, prostate cancer, and other cancers. The exact recommendation depends on the cancer type, stage, and country-specific guidelines. Always follow the advice of your treating oncology team. |
| ICMR Guideline | Indian Council of Medical Research and national cancer guidelines recognise docetaxel as part of standard chemotherapy for breast cancer, non-small cell lung cancer, prostate cancer, gastric cancer, and head and neck cancer. Treatment should be given in a recognised cancer centre with proper monitoring. Always follow the advice of your treating oncology team. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to the beta-tubulin subunit of microtubules inside cells. This binding stabilises the microtubule polymer and prevents it from disassembling, which disrupts the normal dynamic assembly and disassembly needed for cell division. As a result, cancer cells cannot complete mitosis, they arrest in the G2/M phase of the cell cycle, and they eventually die by apoptosis. Because cancer cells divide more often than most normal cells, they are more sensitive to this effect, although normal tissues that divide quickly, such as bone marrow, hair follicles, and the lining of the mouth and gut, are also affected, which explains many of the side effects.
Mechanism Steps
💡 How to Take Relidoce 80mg Injection
Strength: This medicine is supplied as an 80 mg single-dose vial of concentrate for solution for intravenous infusion.
Dosage Information
| Adult Dosage | The dose of this medicine is calculated from body surface area and depends on the type of cancer, the treatment regimen, and whether it is used alone or with other medicines. Common schedules include 75 mg per square metre of body surface area every three weeks, or 100 mg per square metre every three weeks in some regimens, or 35 mg per square metre weekly for several weeks. Premedication with a corticosteroid is usually given before each infusion to reduce fluid retention and allergic reactions. Dose must be individualized by a qualified clinician based on indication, age, weight, blood counts, liver function, and kidney function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatric oncologist. |
| Elderly Dosage | Patients over 65 years of age may be more sensitive to the side effects of this medicine, especially low blood counts, fluid retention, and nerve damage. Doctors often start with a lower dose or use a gentler schedule and monitor blood counts and liver function more closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Mild to moderate kidney problems usually do not require a dose change because this medicine is mainly cleared by the liver. Patients with severe kidney disease or those on dialysis should be monitored closely, and the dose must be individualized by a qualified clinician. |
| Hepatic Impairment | Patients with abnormal liver tests may need a reduced dose because this medicine is broken down in the liver. If bilirubin is elevated or liver enzymes are significantly raised, the dose is often reduced by 25% or more, or treatment may be delayed. Severe liver impairment is a contraindication. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum dose depends on the treatment regimen and body surface area. Common single doses range from 75 mg per square metre to 100 mg per square metre every three weeks, or 35 mg per square metre weekly. The total dose must never exceed the limit set by your oncology team. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Relidoce 80mg Injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Rifampicin | Major | |
| Phenytoin | Major | |
| Carbamazepine | Major | |
| St John's wort | Major | |
| Live vaccines | Major | |
| Warfarin | Moderate | |
| Doxorubicin | Moderate | |
| Ciclosporin | Moderate | |
| Paracetamol | Minor |
🚨 Major Interactions
- Strong CYP3A4 inhibitors such as ketoconazole, itraconazole, clarithromycin, and ritonavir
- Strong CYP3A4 inducers such as rifampicin, phenytoin, carbamazepine, and St John's wort
- Live vaccines
- Other myelosuppressive chemotherapy or radiotherapy
⚡ Moderate Interactions
- Warfarin and other blood thinners
- Doxorubicin and other anthracyclines
- Ciclosporin and tacrolimus
🍷 Alcohol Interaction
Alcohol should be avoided or strictly limited while receiving this medicine. Alcohol can increase the risk of liver problems, worsen nausea and dehydration, and make it harder for your body to recover between chemotherapy cycles. If you drink alcohol regularly, discuss this with your oncology team so they can give you personalised advice.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe allergic reaction to docetaxel or other taxane medicines.","Very low neutrophil count before treatment.","Severe liver impairment.","Pregnancy and breastfeeding.","Use of live vaccines during treatment.","Severe uncontrolled infection."]
⚠️ Warnings & Precautions
["This medicine must be given only by a qualified oncology professional in a properly equipped facility.","Premedication with corticosteroids is usually given to reduce fluid retention and allergic reactions.","Blood counts must be checked before each cycle, and treatment may be delayed or reduced if counts are low.","Patients with liver problems may need a lower dose and closer monitoring.","Patients over 65 years may be more sensitive to side effects and may need dose adjustments.","Avoid pregnancy during treatment and for at least six months after the last dose.","Do not breastfeed during treatment.","Report fever, chills, sore throat, mouth ulcers, unusual bleeding, breathlessness, or rapid weight gain immediately.","Avoid driving or operating machinery if you feel dizzy, tired, or have nerve symptoms.","Tell your doctor about all other medicines, supplements, and herbal products you are taking."]
🤱 Lactation Safety
This medicine passes into breast milk and could harm a nursing infant. Breastfeeding must be stopped before treatment begins and should not be restarted until your doctor confirms it is safe.
💊 Overdose Management
Overdose with this medicine can cause severe bone marrow suppression, nerve damage, and mouth sores. There is no specific antidote. Treatment is supportive and includes close monitoring of blood counts, prevention and treatment of infection, and management of fluid and electrolyte problems. If an overdose is suspected, contact your oncology team or emergency services immediately.
⏰ Missed Dose
This medicine is given by a healthcare professional in a clinic or hospital, so a missed dose usually means a missed appointment. Contact your oncology team as soon as possible to reschedule. Do not try to catch up by taking extra doses or changing the schedule on your own.
Additional Safety Advice
This medicine must be given only by a trained oncology nurse or doctor in a hospital or day-care chemotherapy setting. Never attempt to handle or inject this medicine at home. Inform your doctor about all medicines, vitamins, and herbal products you take, especially ketoconazole, rifampicin, phenytoin, carbamazepine, and St John's wort, because these can change how this medicine works. Use effective contraception during treatment and for at least six months after the last dose for men and women, and do not breastfeed during treatment. Avoid live vaccines while on this medicine. Drink enough fluids unless your doctor restricts them, and report any fever, chills, sore throat, mouth ulcers, unusual bleeding, breathlessness, or rapid weight gain without delay. Do not drive or operate heavy machinery if you feel dizzy, tired, or have nerve symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Patients over 65 years of age may be more sensitive to the side effects of this medicine, especially low blood counts, fluid retention, mouth sores, and nerve damage. Doctors often use a lower dose or a gentler schedule and monitor blood counts, liver function, and fluid balance more closely. Older patients should also be assessed for falls risk, nutrition, and other medical conditions before and during treatment.
🤰 Pregnancy Planning (TTC)
This medicine can harm a developing baby and should not be used during pregnancy. Both men and women should use effective contraception during treatment and for at least six months after the last dose. If you are planning a pregnancy, discuss it with your oncology team well in advance so that treatment can be planned safely. Fertility preservation options should be discussed before starting chemotherapy.
🏥 Post-Surgery Considerations
This medicine may be given before or after surgery as part of cancer treatment. After surgery, your doctor will decide when it is safe to start chemotherapy based on wound healing, blood counts, and your overall recovery. Follow your surgeon's and oncologist's instructions about wound care, activity, and when to resume treatment.
🦷 Dental Procedures
Tell your dentist that you are receiving this medicine before any dental procedure. Chemotherapy can increase the risk of infection and bleeding, so dental work may need to be timed around your treatment cycles. Your dentist and oncologist should discuss whether antibiotics or other precautions are needed. Maintain good oral hygiene and report any mouth sores or dental pain to your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Light to moderate exercise such as walking or gentle stretching can help with tiredness and mood, but you should avoid strenuous activity, contact sports, or heavy lifting, especially when your blood counts are low. If you have numbness, tingling, or balance problems, choose exercises that reduce the risk of falls. Always check with your oncology team before starting or changing an exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause tiredness, nausea, and nerve symptoms that may affect your ability to work or drive. Many patients need to take time off during treatment cycles, especially around the days when blood counts are lowest. Avoid driving or operating heavy machinery if you feel dizzy, tired, or have numbness or tingling. Discuss your work schedule with your oncology team so they can help you plan rest periods and treatment appointments.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your oncology team will decide when to stop based on your response to treatment, side effects, blood counts, and overall health. If you develop severe side effects such as a high fever, breathing difficulty, severe mouth sores, or worsening nerve symptoms, contact your doctor immediately. They may delay, reduce, or stop treatment depending on your condition.
📅 Long-Term Use Effects
Long-term effects of this medicine can include persistent numbness or tingling in the hands and feet, ongoing tiredness, changes in hair texture, and, rarely, heart or lung problems. Some patients may experience long-lasting fluid retention or nail changes. Regular follow-up with your oncology team is important to monitor for late effects, and any new or worsening symptoms should be reported. Most side effects improve after treatment ends, but some may take months to resolve.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the cancer type and stage, other chemotherapy combinations or single agents may be used instead of or in addition to this medicine.
Evidence: Well-establishedFor some cancers, targeted medicines that act on specific cancer cell changes may be used alone or with chemotherapy.
Evidence: Well-established for selected cancersIn certain cancers, immunotherapy may be an option, sometimes in combination with chemotherapy.
Evidence: Established for selected cancersRadiation may be used alone or with chemotherapy for local control of certain tumours.
Evidence: Well-establishedSupportive care focuses on relieving symptoms and improving quality of life at any stage of cancer treatment.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Live vaccines should not be given during treatment with this medicine because the immune system is weakened and live vaccines can cause serious infections. Inactivated vaccines may be given, but they may not work as well. Discuss all vaccinations with your oncology team and avoid close contact with people who have recently received live vaccines.
📦 Storage Guide
✅ DO
Store the unopened vial in a refrigerator between 2°C and 8°C.
❌ DON'T
Do not freeze the vial.
✅ DO
Keep the vial in its original carton to protect it from light.
❌ DON'T
Do not store it in direct sunlight or in a hot place.
✅ DO
Follow the pharmacy or hospital instructions for prepared solutions.
❌ DON'T
Do not prepare or store the infusion solution at home.
✅ DO
Check the expiry date before use.
❌ DON'T
Do not use the medicine if the solution is cloudy or contains particles.
✈️ Traveling with This Medicine
This medicine is given in a hospital or chemotherapy day-care centre, so travel should be planned around your treatment schedule. If you need to travel, carry a copy of your prescription and a letter from your oncologist explaining your diagnosis, treatment, and medicines. Keep the medicine in its original packaging and follow the storage instructions provided by your pharmacy. If you are travelling by air, carry medicines in your hand luggage with proper documentation. Discuss any planned travel with your oncology team well in advance so that your treatment schedule and blood tests can be arranged safely.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The medicine starts affecting cancer cells soon after it enters the body, but measurable shrinkage of tumours usually takes several weeks. Your doctor will assess response with scans and tests after one or more cycles.
A: This medicine is given as an intravenous infusion by a trained healthcare professional in a hospital or chemotherapy day-care centre. It is usually given over about one hour, and you will be monitored during and after the infusion.
A: Common side effects include low blood counts, hair loss, tiredness, nausea, mouth sores, muscle and joint pain, numbness or tingling in the hands and feet, and fluid retention. Your doctor will help you manage these.
A: No. This medicine must be given only by a trained healthcare professional in a hospital or chemotherapy centre. It should never be injected at home.
A: This medicine can harm a developing baby. Use effective contraception during treatment and for at least six months after the last dose. Discuss family planning with your doctor before starting treatment.
A: A fever of 38°C or higher during chemotherapy is a medical emergency. Contact your oncology team or go to the nearest emergency department immediately, even if you feel only mildly unwell.
🤔 Common Patient Concerns
🔄 Substitutes for Relidoce 80mg Injection
View AllAlternative brands with exact same active ingredient:
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docax 80mg injectionNeon Laboratories Ltd ₹2,171.00 55.1% COSTLIER
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dc fill 80mg injectionFourrts India Laboratories Pvt Ltd ₹2,203.13 57.4% COSTLIER
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chemodoc 80mg injectionLupin Ltd ₹4,597.16 228.4% COSTLIER
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zenotere 80mg injectionSun Pharmaceutical Industries Ltd ₹5,400.00 285.7% COSTLIER
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innotubilin 80mg injectionInnova Formulations Pvt Ltd ₹5,475.00 291.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken as a tablet at home.
Fact: This medicine is an intravenous chemotherapy medicine and must be given by a trained healthcare professional in a hospital or day-care setting. - Myth: Hair loss from this medicine is permanent.
Fact: Hair loss is usually temporary, and hair often grows back after treatment is completed, although the colour and texture may change. - Myth: Chemotherapy always makes you very sick.
Fact: Modern supportive medicines can prevent or reduce nausea, vomiting, and other side effects, so many patients manage treatment better than they expect. - Myth: You can stop this medicine whenever you feel better.
Fact: Stopping chemotherapy without medical advice can allow the cancer to return or grow. Always discuss any concerns with your oncology team.
🔄 Alternative Options
Generic Alternatives
- Docetaxel generic injection
Brand Alternatives
- Taxotere 80mg injection