Bactomet 150mg/100mg Suspension: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain that does not go away
- Seizure or loss of consciousness
- Tingling, numbness, or burning in the hands or feet
- Sudden pain, swelling, or weakness in a tendon
- Severe skin rash, blisters, or peeling skin
- Yellowing of the skin or eyes
- Decreased urine output or swelling in the legs
- Chest pain, palpitations, or difficulty breathing
- Severe headache with confusion or vision changes
If experiencing severe symptoms, call emergency services immediately.
What is betadix syrup used for?
This medicine is a combination of nalidixic acid and metronidazole used to treat certain mixed bacterial and protozoal infections. It works by stopping the growth of susceptible organisms. It should be taken exactly as prescribed, with food, and without alcohol.
- Generic Name: Nalidixic Acid + Metronidazole
- Manufacturer: Agron Remedies Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 betadix syrup के बारे में (Hindi Summary)
उपयोग: यह दवा नालिडिक्सिक एसिड और मेट्रोनिडाजोल का संयोजन है, जिसका उपयोग कुछ प्रकार के बैक्टीरियल और प्रोटोज़ोअल संक्रमणों के इलाज के लिए किया जाता है। यह आमतौर पर दस्त, पेट के संक्रमण और मूत्र मार्ग के संक्रमण में दी जाती है। यह दवा संक्रमण पैदा करने वाले कीटाणुओं की वृद्धि को रोकती है। इसे डॉक्टर के बताए अनुसार ही लें और कोर्स पूरा करें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में जी मिचलाना, उल्टी, पेट दर्द, दस्त, सिरदर्द, चक्कर आना और मुँह में धातु जैसा स्वाद शामिल हैं। कुछ लोगों को नींद आना या धुंधला दिखाई देना भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन दौरे, हाथ-पैर में झुनझुनी, टेंडन में दर्द या त्वचा पर गंभीर दाने हो सकते हैं। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। हर बार लेने से पहले बोतल को अच्छी तरह हिलाएँ। दवा को भोजन या दूध के साथ लें ताकि पेट की परेशानी कम हो। इस दवा के साथ शराब बिल्कुल न पिएँ और आखिरी खुराक के 48 घंटे बाद तक भी न पिएँ। अगर चक्कर आएँ या नींद आए तो वाहन न चलाएँ। कोर्स पूरा करें, बीच में दवा न छोड़ें। एंटासिड या आयरन की गोलियाँ इस दवा से दो घंटे पहले या बाद में लें।
💊 betadix syrup Uses & Benefits
[{"condition":"Infectious diarrhea caused by susceptible bacteria","description":"This medicine may be used when a clinician suspects a mixed bacterial infection involving both aerobic and anaerobic organisms.","evidence":"Limited"},{"condition":"Urinary tract infection with mixed organisms","description":"Nalidixic acid covers some gram-negative urinary pathogens, while metronidazole covers certain anaerobes that may complicate the infection.","evidence":"Limited"},{"condition":"Gastrointestinal infection with Giardia or Entamoeba","description":"Metronidazole is active against certain protozoa, and the combination may be chosen when a mixed infection is suspected.","evidence":"Limited"}]
Off-label uses: [{"condition":"Prophylaxis in selected gastrointestinal procedures","description":"Rarely, a clinician may consider this combination when anaerobic coverage is needed, but this is not a standard approved use.","evidence":"Limited"}]
Primary treatment for: Mixed bacterial and protozoal gastrointestinal or urinary tract infections
Also treats: Infectious diarrhea, Urinary tract infection, Giardiasis, Amebiasis
📋 Drug Information
| Generic Name(s) | Nalidixic Acid + Metronidazole |
| Brand Name | Abicon |
| Manufacturer | Agron Remedies Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antibacterial + Antiprotozoal |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Do not freeze. Keep the bottle tightly closed when not in use. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture, unless otherwise stated on the label. Do not use after the expiry date printed on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different mechanisms. Nalidixic acid inhibits bacterial DNA gyrase and topoisomerase IV, enzymes needed for DNA replication and repair. This stops susceptible bacteria from multiplying. Metronidazole enters microbial cells and is reduced by ferredoxin-like proteins in anaerobic organisms. The reduced form creates reactive radicals that damage DNA and disrupt essential cellular functions. Together, these actions target a broader range of organisms than either ingredient alone.
Mechanism Steps
💡 How to Take betadix syrup
Strength: Each 5 mL of suspension contains nalidixic acid 150 mg and metronidazole 100 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is determined by your doctor based on the type and severity of the infection, your kidney and liver function, and your body weight. A common schedule is one measured dose taken two to four times daily, but the exact dose and frequency must be individualized by a qualified clinician. Do not change the dose or frequency without consulting your doctor. Complete the full course as prescribed, even if symptoms improve early. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Older adults may be more sensitive to the side effects of this medicine, especially dizziness, confusion, and tendon problems. Kidney function often declines with age, so the dose may need to be adjusted. Your doctor will determine the appropriate dose based on your kidney function and overall health. |
| Renal Impairment | Nalidixic acid is excreted by the kidneys, and its dose may need to be reduced in people with kidney impairment. Metronidazole may also require dose adjustment in severe kidney disease. Your doctor will check your kidney function and adjust the dose accordingly. Stay well hydrated while taking this medicine. |
| Hepatic Impairment | Metronidazole is metabolized in the liver, and its dose may need to be reduced in people with severe liver disease. Nalidixic acid can also affect liver enzymes. Your doctor will monitor your liver function and adjust the dose if needed. Avoid this medicine if you have severe liver disease unless specifically advised by your doctor. |
| Maximum Daily Dose | The maximum daily dose must be determined by a qualified clinician based on the indication, age, weight, kidney function, and liver function. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of betadix syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Alcohol | Major | |
| Antacids | Major | |
| Iron supplements | Major | |
| Cimetidine | Moderate | |
| Phenytoin | Moderate | |
| Lithium | Moderate | |
| Cyclosporine | Moderate | |
| Oral contraceptives | Minor | |
| Theophylline | Minor |
🚨 Major Interactions
- Warfarin
- Alcohol
- Antacids containing magnesium or aluminum
- Iron supplements
⚡ Moderate Interactions
- Cimetidine
- Phenytoin
- Lithium
- Cyclosporine
🍷 Alcohol Interaction
Do not drink alcohol while taking this medicine and for at least 48 hours after the last dose. Metronidazole can cause a disulfiram-like reaction with alcohol, leading to severe nausea, vomiting, flushing, headache, and rapid heartbeat. Alcohol can also worsen dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to nalidixic acid, metronidazole, or any other quinolone or nitroimidazole","History of tendon rupture or tendonitis with quinolone antibiotics","History of seizures or severe nerve problems","Severe liver disease","Recent alcohol consumption","Use of disulfiram within the past two weeks","Pregnancy, unless clearly needed and advised by a doctor","Breastfeeding, unless advised by a doctor"]
⚠️ Warnings & Precautions
["This medicine can cause dizziness and drowsiness. Avoid driving or operating machinery until you know how it affects you.","Do not drink alcohol during treatment and for at least 48 hours after the last dose.","Tell your doctor if you have kidney or liver problems, as dose adjustment may be needed.","Stop the medicine and seek urgent care if you develop tendon pain, swelling, or weakness.","Report tingling, numbness, or burning in the hands or feet to your doctor.","This medicine can make your skin more sensitive to sunlight. Use sunscreen and avoid prolonged sun exposure.","Do not use this medicine to treat a viral infection such as the common cold or flu.","Keep this medicine out of reach of children.","Complete the full course as prescribed, even if you feel better.","Tell your doctor about all other medicines you are taking, including over-the-counter products."]
🤱 Lactation Safety
Both nalidixic acid and metronidazole pass into breast milk. Metronidazole may cause diarrhea or thrush in a nursing infant. If you are breastfeeding, talk to your doctor before taking this medicine. Your doctor may advise you to pump and discard breast milk during treatment and for a period after the last dose.
💊 Overdose Management
If you or someone else takes too much of this medicine, seek emergency medical help immediately. Symptoms of overdose may include severe nausea, vomiting, dizziness, confusion, seizures, and difficulty breathing. Do not try to induce vomiting unless instructed by a medical professional. Treatment is supportive and may include activated charcoal, intravenous fluids, and monitoring of vital signs and organ function.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Shake the bottle well before each dose to ensure the suspension is evenly mixed. Measure the dose with the spoon or cup provided, not with a household spoon. Take it with food or milk to reduce stomach upset. Drink plenty of water throughout the day. Do not drink alcohol while taking this medicine and for at least 48 hours after the last dose, because metronidazole can cause a severe reaction with alcohol. Avoid driving or operating heavy machinery if you feel dizzy or drowsy. Do not stop the course early, even if you feel better, because stopping too soon can allow the infection to return. Keep this medicine out of reach of children. Tell your doctor if you have kidney or liver problems, nerve problems, or a history of seizures. Do not take antacids or iron supplements within two hours of this medicine, as they can reduce its absorption.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more likely to experience dizziness, confusion, and tendon problems with this medicine. Kidney function often declines with age, so the dose may need to be adjusted. Your doctor should check your kidney and liver function before prescribing and monitor you closely during treatment. Avoid driving or operating machinery if you feel dizzy or drowsy.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, talk to your doctor before taking this medicine. Both nalidixic acid and metronidazole should be used during pregnancy only when clearly needed and advised by a doctor. Your doctor may recommend an alternative treatment or delay treatment until after pregnancy. Use effective contraception during treatment and for a period after, as advised by your doctor.
🏥 Post-Surgery Considerations
If you have recently had surgery, tell your surgeon and doctor that you are taking this medicine. It may interact with other medicines used during or after surgery, and it can affect wound healing if the infection is not fully treated. Your doctor will decide whether to continue, adjust, or stop the medicine before and after surgery.
🦷 Dental Procedures
Tell your dentist that you are taking this medicine before any dental procedure. Metronidazole can interact with other medicines used during dental work, and the combination may increase the risk of bleeding if you are also taking blood thinners. Your dentist may recommend postponing non-urgent procedures until you have completed the course.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you feel dizzy, drowsy, or weak. This medicine can cause dizziness and tendon problems, so stop exercising and seek medical advice if you develop joint or tendon pain. Light activity such as walking is usually fine if you feel well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause dizziness, drowsiness, and blurred vision, which may affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. If your work involves operating heavy equipment or driving, talk to your doctor about temporary adjustments. Most people can continue their usual daily activities with caution.
🛑 When to Stop This Medicine
Stop taking this medicine and contact your doctor immediately if you develop tendon pain, swelling, or weakness; tingling or numbness in the hands or feet; a seizure; a severe skin rash; or yellowing of the skin or eyes. Do not stop the medicine on your own for other reasons without consulting your doctor, as stopping early can allow the infection to return.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless specifically advised by your doctor. Prolonged use can increase the risk of nerve damage, tendon problems, and resistant infections. Your doctor may monitor your kidney and liver function, blood counts, and nerve symptoms if you need to take it for an extended period. Always discuss the risks and benefits with your doctor before starting long-term treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps replace fluids and electrolytes lost due to diarrhea and supports recovery.
Evidence: Well-establishedMay help restore healthy gut bacteria, especially after antibiotic treatment.
Evidence: LimitedEating bland, easy-to-digest foods can help reduce stomach upset during treatment.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the effectiveness of live bacterial vaccines such as the typhoid vaccine. Talk to your doctor about the timing of vaccinations while taking this medicine. In general, avoid live vaccines during treatment unless specifically advised by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not freeze the suspension
✅ DO
Keep the bottle tightly closed when not in use
❌ DON'T
Do not leave the cap off for long periods
✅ DO
Protect from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not transfer to another container
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case customs or security asks for it. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, keep your dosing schedule as close to the original as possible, but do not double up on doses. Avoid alcohol during travel and for 48 hours after the last dose. If you are flying, keep the suspension in your carry-on bag if you need it during the flight.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 24 to 48 hours, but you must complete the full course as prescribed to fully clear the infection.
A: Yes, taking it with food or milk is recommended to reduce stomach upset.
A: If you remember within half the dosing interval, take the missed dose. If it is almost time for the next dose, skip it and continue with your regular schedule. Do not double dose.
A: No. Alcohol can cause a severe reaction with metronidazole. Avoid alcohol during treatment and for at least 48 hours after the last dose.
A: Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
🤔 Common Patient Concerns
🔄 Substitutes for betadix syrup
View AllAlternative brands with exact same active ingredient:
-
ad 150mg/100mg suspensionVeritaz Healthcare Ltd ₹10.22 14.8% CHEAPER
-
matrix mn suspensionMacleods Pharmaceuticals Pvt Ltd ₹11.10 7.5% CHEAPER
-
mexigyl suspensionMedicaman Biotech Ltd ₹12.85 7.1% COSTLIER
-
bactomet 150mg/100mg suspensionWin-Medicare Pvt Ltd ₹22.72 89.3% COSTLIER
-
gramoneg m 150 mg/100 mg suspensionSun Pharmaceutical Industries Ltd ₹22.86 90.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any stomach infection.
Fact: This medicine only works against certain susceptible bacteria and protozoa. It is not effective against viral infections or all types of bacteria. - Myth: I can stop taking this medicine as soon as I feel better.
Fact: You must complete the full course as prescribed. Stopping early can allow the infection to return and can lead to resistance. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol can cause a severe reaction with metronidazole. Avoid alcohol completely during treatment and for 48 hours after.
🔄 Alternative Options
Generic Alternatives
- Nalidixic acid and metronidazole oral suspension