agrocin 250mg tablet - Erythromycin (250mg) medicine

Althrocin 250 Tablet (Erythromycin 250mg): Complete Medicine Guide

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🏭 Agron Remedies Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for many bacterial infections; evidence varies by indication.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe or bloody diarrhea
  • Yellowing of skin or eyes (jaundice)
  • Dark urine or pale stools
  • Fast, irregular, or pounding heartbeat
  • Fainting or dizziness
  • Swelling of face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Sudden hearing loss or ringing in the ears
  • Severe abdominal pain that radiates to the back

If experiencing severe symptoms, call emergency services immediately.

What is agrocin 250mg tablet used for?

This medicine is an oral antibiotic containing erythromycin 250 mg. It treats bacterial infections by stopping bacteria from making proteins. Take it exactly as prescribed, usually every 6 hours, and complete the full course.

  • Generic Name: Erythromycin
  • Manufacturer: Agron Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 agrocin 250mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एरिथ्रोमाइसिन 250 मिलीग्राम की एक मौखिक एंटीबायोटिक गोली है। यह बैक्टीरिया से होने वाले संक्रमणों जैसे सांस की नली के संक्रमण, त्वचा के संक्रमण, और कुछ यौन संचारित रोगों के इलाज में उपयोग की जाती है। यह बैक्टीरिया के प्रोटीन बनाने की प्रक्रिया को रोककर उन्हें मरने में मदद करती है। इसे डॉक्टर के बताए अनुसार ही लें और पूरा कोर्स पूरा करें।

साइड इफेक्ट्स: इस दवा के सबसे आम दुष्प्रभाव पेट से जुड़े होते हैं, जैसे जी मिचलाना, उल्टी, दस्त, और पेट में ऐंठन। ये आमतौर पर हल्के होते हैं और कुछ दिनों में ठीक हो जाते हैं। दवा को भोजन के साथ लेने से पेट की तकलीफ कम हो सकती है। कभी-कभी गंभीर दस्त, लीवर की समस्या, दिल की धड़कन में गड़बड़ी, या सुनने में कमी जैसी गंभीर समस्याएं भी हो सकती हैं। अगर आपको गंभीर या खूनी दस्त, आंखों या त्वचा का पीलापन, तेज या अनियमित धड़कन, या सुनने में अचानक कमी महसूस हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को शुरू करने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं, खासकर लीवर की बीमारी, दिल की धड़कन की समस्या, या मायस्थेनिया ग्रेविस के बारे में बताएं। अपनी सभी दवाओं, सप्लीमेंट्स और हर्बल उत्पादों की सूची दें, क्योंकि यह कई दवाओं के साथ परस्पर क्रिया करती है। इस दवा को लेते समय शराब न पिएं। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं, या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। यह दवा किसी और के साथ साझा न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 agrocin 250mg tablet Uses & Benefits

[{"condition":"Respiratory tract infections","description":"Used to treat community-acquired pneumonia, acute bronchitis, and pertussis (whooping cough) caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Effective against many streptococcal and staphylococcal skin infections, including impetigo and erysipelas.","evidence":"Well-established"},{"condition":"Sexually transmitted infections","description":"Used for chlamydial urethritis and cervicitis, and as an alternative for gonorrhea in penicillin-allergic patients.","evidence":"Well-established"},{"condition":"Diphtheria and pertussis","description":"Used for treatment and post-exposure prophylaxis of diphtheria and pertussis.","evidence":"Well-established"},{"condition":"Legionnaires' disease","description":"An alternative treatment for Legionella pneumonia, especially in combination with other antibiotics.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Gastroparesis","description":"Sometimes used off-label to stimulate stomach emptying in diabetic gastroparesis, but this is not a first-line treatment.","evidence":"Limited"},{"condition":"Acne vulgaris","description":"Oral erythromycin has been used off-label for inflammatory acne, though topical forms are preferred.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Skin infections, Sexually transmitted infections, Pertussis, Diphtheria

📋 Drug Information

Generic Name(s)Erythromycin
Brand NameAlthrocin 500 Tablet
ManufacturerAgron Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassMacrolides
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from direct sunlight and moisture. Keep in the original container.
Shelf LifeTypically 24 months from the date of manufacture, but check the expiry date on the package.
WHO GuidelineErythromycin is included in the WHO Model List of Essential Medicines for the treatment of several bacterial infections, including pertussis, diphtheria, and chlamydial infections. It is also recommended as an alternative for penicillin-allergic patients.
ICMR GuidelineThe Indian Council of Medical Research (ICMR) includes erythromycin in its treatment guidelines for community-acquired pneumonia and other respiratory infections, with consideration of local resistance patterns.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with a full glass of water, preferably with food to reduce stomach upset.
2
Complete the full course even if you feel better after a few days.
3
Avoid taking antacids within 2 hours of this medicine as they can reduce its absorption.
4
Inform your doctor if you have liver disease, heart rhythm problems, or myasthenia gravis before starting this medicine.
5
Do not drink alcohol while taking this medicine as it can worsen side effects.
6
Report any severe or bloody diarrhea, yellowing of eyes, or irregular heartbeat immediately.
7
Use backup contraception if you are on oral contraceptive pills, as this medicine may reduce their effectiveness.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Fever with cough and chest congestion
This medicine is commonly prescribed for respiratory tract infections.
Likely Use
Skin redness, swelling, and pus
This medicine is used for skin and soft tissue infections.
Likely Use
Common cold
This medicine is not effective against viral infections like the common cold.
Not Primary
Painful urination with discharge
This medicine may be used for certain sexually transmitted infections like chlamydia.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionErythromycin base is partially absorbed from the small intestine, but absorption is reduced by stomach acid. Food may slightly delay absorption but does not significantly reduce the total amount absorbed. The bioavailability of the base form is variable, typically around 30-65% depending on the formulation and stomach contents.
DistributionThis medicine is widely distributed throughout body tissues and fluids, including the lungs, liver, kidneys, and spleen. It crosses the placenta and is excreted in breast milk. It does not penetrate the cerebrospinal fluid well when the meninges are not inflamed, so it is not used for central nervous system infections.
Protein BindingErythromycin is approximately 70-90% bound to plasma proteins, primarily to alpha-1-acid glycoprotein and albumin.
MetabolismThis medicine is extensively metabolized in the liver by the cytochrome P450 enzyme system, particularly CYP3A4. It is demethylated and dehydrated to form several metabolites, some of which are inactive. Because it inhibits CYP3A4, it can increase the levels of many other drugs.
Half-LifeThe elimination half-life of erythromycin is approximately 1.5 to 2 hours in healthy adults, but it may be prolonged in patients with liver disease.
ExcretionThis medicine is primarily excreted in the bile and feces, with only a small amount (2-5%) excreted unchanged in the urine. This makes it a good choice for patients with kidney problems, but dose adjustment may be needed in severe liver disease.
BioavailabilityThe oral bioavailability of erythromycin base is approximately 30-65%, but it can be lower if taken with food or if stomach acid is high.
Onset of ActionThe onset of action for this medicine is typically within 1-2 hours after taking a dose, but clinical improvement of the infection may take 24-48 hours.
Peak Plasma TimePeak plasma concentrations are usually reached 1-4 hours after oral administration, depending on the formulation and whether it is taken with food.
Duration of ActionThe antibacterial effect of a single dose lasts approximately 6-12 hours, which is why it is usually taken multiple times a day.

How It Works

This medicine works by binding to the 50S ribosomal subunit of susceptible bacteria, blocking the translocation step of protein synthesis. Without the ability to build new proteins, the bacteria cannot grow or multiply, and they eventually die. This action is primarily bacteriostatic at usual doses, meaning it stops bacterial growth rather than directly killing the bacteria, but it can be bactericidal at higher concentrations against very susceptible organisms.

Mechanism Steps

1
Entry into bacterial cell: This medicine diffuses through the bacterial cell wall and membrane into the cytoplasm.
2
Binding to 50S subunit: It binds reversibly to a specific site on the 50S ribosomal subunit, near the peptidyl transferase center.
3
Blocking translocation: This binding prevents the ribosome from moving along the mRNA strand, which stops the addition of new amino acids to the growing protein chain.
4
Inhibition of protein synthesis: Without new proteins, the bacteria cannot maintain essential cellular functions, leading to growth arrest and death.

💡 How to Take agrocin 250mg tablet

Strength: Erythromycin 250 mg immediate-release tablet

1Take this medicine by mouth with a full glass of water.
2You may take it with or without food, but taking it with food may reduce stomach upset.
3Swallow the tablet whole. Do not crush, chew, or break it unless your doctor advises.
4Take it at evenly spaced intervals as prescribed by your doctor.
5Complete the full course of treatment even if you feel better after a few days.
6Do not take antacids within 2 hours of this medicine, as they may reduce its absorption.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 250 mg taken every 6 hours, or 500 mg every 12 hours, depending on the type and severity of the infection. For severe infections, doses up to 4 grams per day may be used in divided doses. The exact dose and duration must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and response to treatment. Always follow your doctor's prescription exactly.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially hearing loss and heart rhythm changes. Dose adjustment may be necessary based on kidney and liver function. Consult your doctor for personalized dosing.
Renal ImpairmentErythromycin is primarily excreted in bile, so dose adjustment is usually not required in patients with kidney disease. However, use with caution and monitor for side effects if kidney function is severely impaired.
Hepatic ImpairmentIn patients with severe liver disease, the half-life of erythromycin may be prolonged. Dose reduction or avoidance may be necessary. Consult your doctor for personalized dosing.
Maximum Daily DoseThe maximum recommended daily dose for adults is 4 grams, but this should only be used in severe infections under close medical supervision.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit juice
Avoid
May increase drug levels and side effects.
Antacids
Separate by 2 hours
Antacids can reduce absorption of this medicine.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of agrocin 250mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or a full glass of water. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or bloody, seek medical attention.
Abdominal cramps (Common (5-10%))
Take with food. If cramps are severe, contact your doctor.
Vomiting (Uncommon (1-5%))
Take with food and avoid large meals. If vomiting continues, consult your doctor.
Metallic taste (Uncommon (1-5%))
Usually temporary. Chewing sugar-free gum may help.

🚨 Serious Side Effects

Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Seek immediate medical attention if you develop severe, watery, or bloody diarrhea, even weeks after finishing the antibiotic.
Liver toxicity (hepatitis, cholestatic jaundice) (Rare (<0.1%))
Stop the medicine and seek immediate care if you notice yellowing of eyes or skin, dark urine, or severe abdominal pain.
QT prolongation and ventricular arrhythmias (Rare (<0.1%))
Seek emergency care if you experience palpitations, fainting, or irregular heartbeat.
Severe allergic reactions (anaphylaxis, angioedema) (Rare (<0.1%))
Call emergency services immediately if you have swelling of the face, lips, tongue, or throat, or difficulty breathing.
Hearing loss (usually reversible) (Rare (<0.1%))
Report any ringing in the ears or hearing changes to your doctor promptly.

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Seek immediate medical attention if you develop a painful rash with blisters or peeling skin.
Torsades de pointes
Call emergency services if you experience sudden fainting or irregular heartbeat.
Pancreatitis
Seek immediate care for severe upper abdominal pain that radiates to the back.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Cisapride Major
Pimozide Major
Ergotamine Major
Simvastatin Major
Warfarin Major
Carbamazepine Moderate
Cyclosporine Moderate
Digoxin Moderate
Theophylline Moderate
Triazolam Moderate

🚨 Major Interactions

  • Cisapride
  • Pimozide
  • Ergotamine and dihydroergotamine
  • Simvastatin and lovastatin
  • Warfarin

⚡ Moderate Interactions

  • Carbamazepine
  • Cyclosporine
  • Digoxin
  • Theophylline
  • Triazolam and midazolam

🍷 Alcohol Interaction

Avoid drinking alcohol while taking this medicine. Alcohol can increase the risk of stomach irritation, nausea, and dizziness. It may also worsen liver-related side effects.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to erythromycin or other macrolide antibiotics","Concurrent use with cisapride, pimozide, or ergotamine","History of erythromycin-associated cholestatic jaundice or liver dysfunction","Concurrent use with certain statins (simvastatin, lovastatin)"]

⚠️ Warnings & Precautions

["Use with caution in patients with liver disease; dose adjustment may be needed.","May cause QT prolongation; avoid in patients with long QT syndrome.","Can cause severe diarrhea; consider C. difficile infection if diarrhea persists.","May interact with many drugs; always check with your pharmacist.","Not effective against viral infections; do not use for colds or flu.","May reduce the effectiveness of oral contraceptives; use backup contraception.","Avoid alcohol during treatment.","Do not share this medicine with others."]

🤱 Lactation Safety

Erythromycin passes into breast milk in small amounts. It is generally considered compatible with breastfeeding, but monitor the infant for diarrhea, thrush, or irritability. Consult your doctor before use.

💊 Overdose Management

Overdose of this medicine may cause severe nausea, vomiting, diarrhea, and hearing loss. There is no specific antidote. Treatment is supportive and symptomatic. If you suspect an overdose, contact your doctor or a poison control center immediately. In severe cases, hospitalization may be required for monitoring and supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Before starting this medicine, tell your doctor about all your medical conditions, especially liver disease, heart rhythm problems, myasthenia gravis, or a history of antibiotic-associated colitis. Provide a complete list of all medicines, supplements, and herbal products you take, because erythromycin interacts with many common drugs including certain statins, blood thinners, migraine medicines, and antiarrhythmics. Do not start or stop any other medicine without checking with your doctor or pharmacist. Avoid alcohol while taking this medicine because it can worsen stomach upset and dizziness. If you are pregnant, planning pregnancy, or breastfeeding, discuss the risks and benefits with your doctor before use. Do not share this medicine with anyone else, even if they have similar symptoms. Keep all follow-up appointments and report any new or worsening symptoms promptly.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to side effects such as hearing loss, heart rhythm disturbances, and drug interactions. Dose adjustment may be needed based on kidney and liver function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, discuss with your doctor before taking this medicine. Erythromycin is generally considered safe during pregnancy, but the risks and benefits should be weighed.

🏥 Post-Surgery Considerations

If you are scheduled for surgery, inform your surgeon and anesthesiologist that you are taking this medicine, as it can interact with certain anesthetic agents and increase the risk of heart rhythm problems.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may interact with certain antibiotics or anesthetics used during dental work.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated by drinking plenty of water.
🥗
Get adequate rest to help your body fight the infection.
😴
Eat a balanced diet rich in fruits and vegetables to support your immune system.
💧
Practice good hand hygiene to prevent the spread of infection.
🧘
Avoid close contact with others while you are contagious.
🌞
Take probiotics if advised by your doctor to prevent antibiotic-associated diarrhea.

🏋️ Exercise Considerations

You can continue light exercise if you feel well, but avoid strenuous activities if you have fever, fatigue, or muscle aches. Listen to your body and rest when needed.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to maintain gut health.
Avoid spicy and oily foods that can worsen stomach upset.
Stay hydrated with water, clear soups, and oral rehydration solutions.
Limit caffeine and alcohol as they can increase stomach irritation.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or stomach upset in some people. Avoid driving or operating heavy machinery until you know how it affects you. You can usually continue your normal daily activities if you feel well, but take it easy if you experience side effects.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and bacterial resistance. If you experience severe side effects, contact your doctor immediately for advice.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to bacterial resistance, superinfections such as oral thrush or C. difficile colitis, and rarely liver toxicity. It is not intended for prolonged use unless specifically directed by a doctor. Regular monitoring of liver function may be needed if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Azithromycin

Another macrolide antibiotic with a longer half-life and fewer drug interactions, taken once daily.

Evidence: Well-established
Clarithromycin

A macrolide antibiotic similar to erythromycin but with better gastrointestinal tolerance.

Evidence: Well-established
Penicillin (if not allergic)

First-line for many bacterial infections if the patient is not allergic.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are due for a vaccine, inform your doctor, as antibiotics may be prescribed for an infection that could affect vaccination timing.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and protect from direct sunlight. If crossing time zones, adjust dosing times gradually under medical advice. Check local customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a skin infection
She was prescribed this medicine for a bacterial skin infection. She took it with food as advised and completed the 7-day course. Her infection cleared up, but she experienced mild nausea for the first two days, which subsided. She emphasized the importance of not skipping doses.
💡 Lesson: Taking the medicine with food helps reduce stomach upset, and completing the full course ensures the infection is fully treated.
👤 A 50-year-old man with community-acquired pneumonia
He was started on this medicine but developed severe diarrhea after 5 days. He stopped the medicine and sought medical help. He was diagnosed with C. difficile infection and required treatment. He learned to report severe diarrhea promptly.
💡 Lesson: Severe diarrhea while on antibiotics can be a sign of a serious condition and should be reported to a doctor immediately.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24-48 hours, but it is important to complete the full course as prescribed.

Q: Can I take it with food?

A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is it safe during pregnancy?

A: Erythromycin is generally considered safe during pregnancy when clearly needed. Consult your doctor before use.

Q: Can I drink alcohol while taking it?

A: It is best to avoid alcohol while taking this medicine as it can worsen stomach upset and dizziness.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my liver?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe for my child?
  • Can I take it with food?

🔄 Substitutes for agrocin 250mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine is an antibiotic and does not work against viruses. It should not be used for colds or flu.
  • Myth: You can stop taking it once you feel better.
    Fact: You must complete the full course to prevent bacterial resistance and recurrence of infection.
  • Myth: It is safe to take with any other medicine.
    Fact: This medicine interacts with many drugs. Always check with your doctor or pharmacist.

🔄 Alternative Options

Generic Alternatives

  • Erythromycin 250 mg tablet (generic)

Brand Alternatives

  • Althrocin 250 tablet
  • Erythrocin 250 tablet
  • Eryc 250 tablet

📊 Comparison with Similar Medicines

[{"medicine":"Erythromycin","class":"Macrolide","common_use":"Respiratory, skin, STI infections","frequency":"Every 6 hours","notes":"Interacts with many drugs"},{"medicine":"Azithromycin","class":"Macrolide","common_use":"Respiratory, skin, STI infections","frequency":"Once daily","notes":"Fewer drug interactions, longer half-life"},{"medicine":"Clarithromycin","class":"Macrolide","common_use":"Respiratory, skin infections, H. pylori","frequency":"Twice daily","notes":"Similar interactions to erythromycin"}]

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