aciloc 150 tablet - Ranitidine (150mg) medicine

Aciloc 150 Tablet: Complete Guide to Uses, Dosage, Side Effects, and Safety

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🏭 Cadila Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in vomit or black, tarry stools
  • Severe abdominal pain that does not go away
  • Chest pain or difficulty breathing
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes (jaundice)
  • Decreased urine output or swelling in legs
  • Confusion or hallucinations (especially in elderly)

If experiencing severe symptoms, call emergency services immediately.

What is aciloc 150 tablet used for?

This medicine contains ranitidine 150 mg, an H2 blocker that reduces stomach acid. It treats heartburn, GERD, and ulcers. Take it orally as prescribed, usually once or twice daily. Common side effects include headache and dizziness. Avoid alcohol. Consult your doctor if pregnant or breastfeeding.

  • Generic Name: Ranitidine
  • Manufacturer: Cadila Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 aciloc 150 tablet के बारे में (Hindi Summary)

उपयोग: यह दवा रैनिटिडीन 150 मिलीग्राम युक्त एक टैबलेट है जो पेट में एसिड का उत्पादन कम करती है। इसका उपयोग सीने में जलन, एसिड रिफ्लक्स, गैस्ट्रोएसोफेजियल रिफ्लक्स डिजीज (जीईआरडी) और पेप्टिक अल्सर के इलाज के लिए किया जाता है। यह पेट के एसिड को कम करके लक्षणों से राहत देती है और अल्सर को भरने में मदद करती है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, चक्कर आना, कब्ज, दस्त, मतली और पेट में असहजता शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें धीमी या अनियमित धड़कन, भ्रम, मतिभ्रम और रक्त विकार शामिल हो सकते हैं। यदि कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से खुराक न बढ़ाएं या लंबे समय तक न लें। यदि आपको गुर्दे या यकृत की बीमारी है तो डॉक्टर को बताएं। इस दवा के साथ शराब न पिएं। यदि आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। अचानक तेज सीने में दर्द या सांस लेने में कठिनाई हो तो तुरंत चिकित्सा सहायता लें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 aciloc 150 tablet Uses & Benefits

[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Reduces stomach acid, providing relief from heartburn and acid regurgitation.","evidence":"Well-established"},{"condition":"Peptic ulcer disease","description":"Helps heal duodenal and gastric ulcers by reducing acid secretion.","evidence":"Well-established"},{"condition":"Heartburn and acid indigestion","description":"Provides short-term relief from occasional heartburn and indigestion.","evidence":"Well-established"},{"condition":"Zollinger-Ellison syndrome","description":"Used to manage excessive acid production in this rare condition.","evidence":"Well-established"},{"condition":"Prevention of stress ulcers","description":"Sometimes used in hospitalized patients to prevent stress-related ulcers.","evidence":"Established"}]

Off-label uses: [{"condition":"Prevention of aspiration pneumonitis","description":"Occasionally used before surgery to reduce stomach acid volume.","evidence":"Limited"},{"condition":"Urticaria (hives)","description":"Sometimes used off-label for chronic hives due to its antihistamine-like effects.","evidence":"Limited"}]

Primary treatment for: Gastroesophageal reflux disease (GERD)

Also treats: Peptic ulcer disease, Heartburn, Zollinger-Ellison syndrome

📋 Drug Information

Generic Name(s)Ranitidine
Brand NameAciloc 150 Tablet
ManufacturerCadila Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassH2 Receptor Blocker
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent acid suppression.
2
If you experience dizziness, avoid driving or operating heavy machinery until you know how it affects you.
3
Do not use this medicine for immediate relief of sudden, severe chest pain; seek emergency care instead.
4
Inform your doctor if you have kidney or liver disease, as dose adjustment may be necessary.
5
Avoid alcohol and caffeine while taking this medicine to prevent worsening of symptoms.
6
If you are on long-term therapy, ask your doctor about monitoring vitamin B12 levels and bone health.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Heartburn
This medicine is commonly prescribed for heartburn.
Likely Use
Acid indigestion
This medicine reduces stomach acid and relieves indigestion.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Headache
This medicine is not for headache relief; it may cause headache as a side effect.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed after oral administration, with peak plasma concentrations occurring within 1 to 3 hours.
DistributionIt is widely distributed throughout the body, including breast milk. It crosses the placenta.
Protein BindingApproximately 15% bound to plasma proteins.
MetabolismIt undergoes hepatic metabolism to a small extent, primarily to N-oxide, S-oxide, and desmethyl metabolites.
Half-LifeThe elimination half-life is approximately 2 to 3 hours in healthy adults, but it is prolonged in patients with kidney impairment.
ExcretionIt is primarily excreted unchanged in the urine. About 30% of an oral dose is excreted in urine as unchanged drug, and the rest as metabolites.
BioavailabilityThe oral bioavailability is approximately 50%.
Onset of ActionOnset of acid reduction occurs within 1 hour after oral administration.
Peak Plasma TimePeak plasma concentration is reached in about 1 to 3 hours.
Duration of ActionThe duration of acid suppression is approximately 8 to 12 hours.

How It Works

This medicine works by competitively blocking histamine H2 receptors located on the parietal cells of the stomach. By blocking these receptors, it reduces the production of gastric acid, both basal and stimulated. This leads to decreased acid volume and concentration in the stomach, allowing ulcers to heal and reducing symptoms of acid reflux.

Mechanism Steps

1
Binding to H2 receptors: This medicine binds to histamine H2 receptors on the surface of gastric parietal cells.
2
Blockade of histamine action: By occupying the receptor, it prevents histamine from stimulating acid production.
3
Reduced acid secretion: This leads to decreased activity of proton pumps and less hydrogen ion secretion into the stomach.
4
Increased gastric pH: The reduced acid output raises the pH in the stomach, which helps relieve symptoms and promote ulcer healing.

💡 How to Take aciloc 150 tablet

Strength: 150 mg immediate-release tablet

1Take this medicine orally with a glass of water.
2You can take it with or without food, but taking it with food may reduce stomach upset.
3Swallow the tablet whole. Do not crush or chew.
4Take at the same time each day to maintain consistent levels.
5Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose for active duodenal ulcer is 150 mg twice daily or 300 mg at bedtime. For maintenance, 150 mg at bedtime is common. For GERD, 150 mg twice daily is often used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on kidney function. Use with caution due to increased risk of confusion and falls.
Renal ImpairmentIn patients with kidney impairment, the dose should be reduced. For creatinine clearance less than 50 mL/min, the usual dose is 150 mg once daily or 50 mg every 12 hours. Consult your doctor for personalized dosing.
Hepatic ImpairmentNo specific dose adjustment is generally required for mild to moderate liver impairment. Use with caution in severe liver disease.
Maximum Daily DoseThe maximum recommended daily dose is 300 mg for oral use, but this may vary based on indication and medical advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Can be taken with or without food
Food does not significantly affect absorption.
Alcohol
Avoid
Increases stomach acid and may worsen symptoms.
Caffeine
Limit
Can increase stomach acid.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of aciloc 150 tablet

✅ Common Side Effects

Headache (Common (1-5%))
Usually resolves on its own. Consult doctor if persistent or severe.
Dizziness (Common (1-5%))
Avoid driving or operating machinery if affected. Consult doctor if it continues.
Constipation (Common (1-5%))
Increase fiber and fluid intake. Consult doctor if it persists.
Diarrhea (Common (1-5%))
Stay hydrated. Consult doctor if it becomes severe or persistent.
Nausea (Common (1-5%))
Take with food. Consult doctor if it continues.

🚨 Serious Side Effects

Slow or irregular heartbeat (Rare (<0.1%))
Seek immediate medical attention if you experience palpitations, fainting, or shortness of breath.
Confusion or hallucinations (Rare (<0.1%))
This is more common in elderly or kidney disease patients. Contact your doctor immediately.
Blood disorders (e.g., thrombocytopenia) (Very rare (<0.01%))
Report unusual bruising or bleeding to your doctor promptly.
Liver inflammation (Very rare (<0.01%))
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Severe allergic reaction (anaphylaxis) (Very rare (<0.01%))
Call emergency services if you experience swelling of face, lips, throat, or difficulty breathing.

⚠️ Rare Side Effects

Pancreatitis
Seek immediate medical attention if you have severe upper abdominal pain radiating to the back.
Agranulocytosis
Report sudden fever, sore throat, or mouth ulcers to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Atazanavir Major
Warfarin Moderate
Metformin Moderate
Procainamide Moderate
Antacids Minor

🚨 Major Interactions

  • Ketoconazole
  • Atazanavir

⚡ Moderate Interactions

  • Warfarin
  • Metformin
  • Procainamide

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can increase stomach acid production and may worsen the condition being treated. It can also increase the risk of stomach irritation and bleeding.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ranitidine or other H2 receptor antagonists","History of acute porphyria"]

⚠️ Warnings & Precautions

["Use with caution in patients with kidney or liver disease; dose adjustment may be needed.","Elderly patients may be more susceptible to confusion and other central nervous system effects.","Do not use for sudden, severe chest pain or difficulty breathing without medical evaluation.","Long-term use may increase the risk of vitamin B12 deficiency and bone fractures.","Avoid alcohol and caffeine while taking this medicine."]

🤱 Lactation Safety

This medicine is excreted in breast milk. It is generally considered safe for use during breastfeeding, but consult your doctor to weigh the benefits and risks.

💊 Overdose Management

Overdose may cause nausea, vomiting, dizziness, and low blood pressure. Seek immediate medical attention. Treatment is supportive and symptomatic. Hemodialysis may be considered in severe cases.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it for longer than recommended without medical advice. Inform your doctor if you have kidney or liver disease, as the dose may need adjustment. Avoid alcohol while taking this medicine, as it can increase stomach acid and worsen your condition. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not use this medicine for sudden, severe chest pain or difficulty breathing, as these may be signs of a heart attack. Keep this medicine out of the reach of children. Store it at room temperature, away from moisture and direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to confusion, dizziness, and falls. Dose adjustment may be needed based on kidney function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor. This medicine is generally considered safe but should be used only if clearly needed. Your doctor may switch you to a safer alternative.

🏥 Post-Surgery Considerations

This medicine may be used after surgery to prevent stress ulcers. Follow your doctor's instructions regarding dosing and duration.

🦷 Dental Procedures

No specific precautions are needed for dental procedures. However, inform your dentist about all medicines you are taking.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce pressure on the stomach.
🥗
Avoid lying down immediately after meals.
😴
Eat smaller, more frequent meals.
💧
Avoid trigger foods like spicy, fatty, or acidic foods.
🧘
Quit smoking and limit alcohol.
🌞
Elevate the head of your bed if you have nighttime reflux.

🏋️ Exercise Considerations

Moderate exercise is generally safe. However, if you experience dizziness or fatigue, avoid strenuous activities until you feel better. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include fiber-rich foods like fruits and vegetables.
Avoid spicy, fatty, and fried foods.
Limit caffeine and carbonated drinks.
Stay well hydrated with water.
Eat smaller meals more frequently.

💼 Impact on Daily Work & Life

This medicine may cause dizziness in some people. If affected, avoid driving or operating heavy machinery. Otherwise, it should not significantly impact your daily work life.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or your symptoms resolve, your doctor may advise tapering or stopping. Abrupt discontinuation may lead to rebound acid hypersecretion.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to vitamin B12 deficiency, increased risk of bone fractures, and possibly increased risk of infections. Regular monitoring and periodic review of the need for continued therapy are recommended.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet changes, weight loss, and avoiding trigger foods can help manage acid reflux.

Evidence: Well-established
Proton pump inhibitors

Another class of acid-suppressing medicines that may be more potent.

Evidence: Well-established
Antacids

Provide quick, short-term relief but do not heal ulcers.

Evidence: Established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, consult your doctor before any vaccination if you are on long-term therapy.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust your dosing schedule gradually as advised by your doctor. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old man with frequent heartburn and acid reflux
He was prescribed this medicine 150 mg twice daily. After one week, his heartburn episodes reduced significantly. He was advised to avoid late-night meals and alcohol. He reported mild headache initially, which resolved after a few days.
💡 Lesson: Taking this medicine regularly and making lifestyle changes can greatly improve GERD symptoms.
👤 A 60-year-old woman with a history of duodenal ulcer
She started this medicine 150 mg at bedtime. Her ulcer pain decreased within two weeks. She was monitored for kidney function due to her age. She was advised to continue for 8 weeks and then reassess.
💡 Lesson: Elderly patients may need dose adjustments and regular monitoring while on this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts reducing acid within 1 hour, but full relief may take a few days.

Q: Can I take it with other medicines?

A: It can interact with certain medicines like ketoconazole and warfarin. Always inform your doctor about all medicines you take.

Q: Is it safe during pregnancy?

A: Consult your doctor. It is generally considered safe but should be used only if clearly needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for aciloc 150 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine provides instant relief from heartburn.
    Fact: It starts working within an hour but may take longer for full effect. It is not for immediate relief of acute symptoms.
  • Myth: This medicine can be taken indefinitely without any risk.
    Fact: Long-term use should be monitored by a doctor due to potential risks like vitamin B12 deficiency and bone fractures.
  • Myth: This medicine is safe to take with alcohol.
    Fact: Alcohol can worsen your condition and increase stomach acid. It is best avoided.

🔄 Alternative Options

Generic Alternatives

  • Ranitidine 150 mg tablet

Brand Alternatives

  • Aciloc 150 tablet

📊 Comparison with Similar Medicines

[{"medicine":"Ranitidine","class":"H2 blocker","onset":"1 hour","duration":"8-12 hours","common_side_effects":"Headache, dizziness"},{"medicine":"Famotidine","class":"H2 blocker","onset":"1 hour","duration":"10-12 hours","common_side_effects":"Headache, dizziness"},{"medicine":"Omeprazole","class":"Proton pump inhibitor","onset":"1 hour","duration":"24 hours","common_side_effects":"Headache, diarrhea"}]

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