anamol plus tablet - Chlorpheniramine Maleate (4mg) + Paracetamol (500mg) medicine

Anamol Plus Tablet: Complete Medicine Guide

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🏭 Angel Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of allergic conditions and fever/pain.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising
  • Seizures
  • Severe dizziness or fainting

If experiencing severe symptoms, call emergency services immediately.

What is anamol plus tablet used for?

This medicine is a combination of Chlorpheniramine Maleate (an antihistamine) and Paracetamol (an analgesic and antipyretic). It is used to treat symptoms of allergies such as runny nose, sneezing, itching, and watery eyes, as well as fever and mild pain. It works by blocking histamine and reducing fever and pain. It should be taken as prescribed, usually every 4-6 hours, and may cause drowsiness.

  • Generic Name: Chlorpheniramine Maleate + Paracetamol
  • Manufacturer: Angel Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 anamol plus tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी और सर्दी-जुकाम के लक्षणों जैसे नाक बहना, छींक आना, आंखों में खुजली और पानी आना, और शरीर में खुजली को कम करने के लिए इस्तेमाल की जाती है। इसमें बुखार और हल्के दर्द को कम करने के लिए पैरासिटामोल भी होता है। यह दवा एलर्जी के कारण होने वाली समस्याओं में राहत देती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि, जी मिचलाना और कब्ज शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, यकृत की समस्या, या रक्त विकार हो सकते हैं। यदि कोई दुष्प्रभाव लंबे समय तक रहे तो डॉक्टर से सलाह लें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से अधिक न लें। नींद आ सकती है, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 anamol plus tablet Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy and watery eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Urticaria","description":"Reduces itching and hives associated with allergic skin reactions.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief from runny nose, sneezing, and fever associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic conjunctivitis","description":"Helps relieve itching, redness, and tearing of the eyes due to allergies.","evidence":"Moderate"},{"condition":"Mild to moderate pain with fever","description":"Paracetamol component reduces fever and relieves mild to moderate pain such as headache, body ache, and toothache.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Insomnia","description":"Sometimes used off-label for its sedative effects to promote sleep, but not recommended due to potential side effects.","evidence":"Limited"},{"condition":"Motion sickness","description":"Chlorpheniramine may be used off-label to prevent motion sickness, but other agents are preferred.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Urticaria, Common cold, Allergic conjunctivitis, Mild to moderate pain with fever

📋 Drug Information

Generic Name(s)Chlorpheniramine Maleate + Paracetamol
Brand NameAlex P Syrup
ManufacturerAngel Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness.
3
Do not consume alcohol while taking this medicine, as it can increase drowsiness and the risk of liver damage.
4
Do not exceed the recommended dose of 6 tablets in 24 hours.
5
Consult your doctor if symptoms persist beyond 7 days or if you develop a fever that worsens.
6
Inform your doctor if you have liver or kidney disease, glaucoma, or difficulty urinating before taking this medicine.
7
If you are pregnant or breastfeeding, consult your doctor before using this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Runny nose
This medicine is commonly prescribed for this.
Likely Use
✅
Sneezing
This medicine is commonly prescribed for this.
Likely Use
✅
Itchy, watery eyes
This medicine is commonly prescribed for this.
Likely Use
✅
Fever
This medicine contains Paracetamol which reduces fever.
Likely Use
✅
Headache
This medicine contains Paracetamol which relieves mild pain.
Likely Use
❌
Cough
This medicine is not a cough suppressant.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorpheniramine Maleate is well absorbed from the gastrointestinal tract after oral administration. Paracetamol is also rapidly and completely absorbed from the gastrointestinal tract. Food may slightly delay the absorption of Paracetamol but does not significantly affect the extent of absorption.
DistributionChlorpheniramine Maleate is widely distributed throughout the body, including the central nervous system. It crosses the placenta and is excreted in breast milk. Paracetamol is distributed widely into most body tissues, with a volume of distribution of approximately 0.9 L/kg. It also crosses the placenta and is excreted in breast milk.
Protein BindingChlorpheniramine Maleate is approximately 70% bound to plasma proteins. Paracetamol is only minimally bound to plasma proteins (about 10-25%).
MetabolismChlorpheniramine Maleate is metabolized in the liver primarily by CYP2D6 and CYP3A4 enzymes. Paracetamol is metabolized in the liver via glucuronidation and sulfation pathways, with a small fraction metabolized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeThe elimination half-life of Chlorpheniramine Maleate is approximately 12-15 hours. The elimination half-life of Paracetamol is about 2-3 hours in adults.
ExcretionChlorpheniramine Maleate and its metabolites are excreted primarily in the urine. Paracetamol and its metabolites are excreted in the urine, with about 90% excreted within 24 hours.
BioavailabilityChlorpheniramine Maleate has a bioavailability of about 25-50% due to first-pass metabolism. Paracetamol has a high oral bioavailability of about 80-100%.
Onset of ActionChlorpheniramine Maleate begins to relieve allergic symptoms within 30-60 minutes after oral administration. Paracetamol starts reducing fever and pain within 30-60 minutes.
Peak Plasma TimeChlorpheniramine Maleate reaches peak plasma concentrations in about 2-6 hours. Paracetamol reaches peak plasma concentrations in about 0.5-2 hours.
Duration of ActionChlorpheniramine Maleate provides symptomatic relief for about 4-6 hours, but its sedative effect may last longer. Paracetamol provides fever and pain relief for about 4-6 hours.

How It Works

This medicine combines two active ingredients. Chlorpheniramine Maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, thereby preventing histamine-mediated allergic responses such as vasodilation, increased vascular permeability, and sensory nerve stimulation. Paracetamol (acetaminophen) acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which results in antipyretic and analgesic effects. The combination provides relief from both allergic symptoms and associated fever or pain.

Mechanism Steps

1
Histamine H1 receptor blockade: Chlorpheniramine Maleate binds to and blocks histamine H1 receptors on effector cells, preventing histamine from eliciting allergic symptoms.
2
Reduction of allergic response: By blocking H1 receptors, it reduces vasodilation, capillary permeability, and sensory nerve stimulation, alleviating sneezing, runny nose, and itching.
3
Central nervous system depression: Chlorpheniramine crosses the blood-brain barrier and causes sedation by blocking central H1 receptors.
4
Antipyretic action of Paracetamol: Paracetamol acts on the hypothalamus to reduce fever by inhibiting prostaglandin synthesis.
5
Analgesic action of Paracetamol: Paracetamol increases the pain threshold by inhibiting prostaglandin synthesis in the central nervous system, providing pain relief.

💡 How to Take anamol plus tablet

Strength: Each tablet contains Chlorpheniramine Maleate 4 mg and Paracetamol 500 mg.

1Take this medicine orally with a glass of water.
2It can be taken with or without food, but taking with food may reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take exactly as prescribed by your doctor.
5Do not exceed the recommended dose.
6If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally every 4 to 6 hours as needed, not to exceed 6 tablets in 24 hours. However, the dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. For short-term use only.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects, especially drowsiness, confusion, and anticholinergic effects. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Paracetamol dose should be reduced or avoided in severe liver disease. Consult a doctor.
Maximum Daily DoseFor adults: Maximum 6 tablets in 24 hours (providing 3000 mg Paracetamol and 24 mg Chlorpheniramine Maleate). Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals or milk
Reduces stomach upset.
Alcohol
Avoid
Increases drowsiness and risk of liver damage.
Caffeine
Moderate intake
May counteract drowsiness but can cause jitteriness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of anamol plus tablet

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. Usually resolves with continued use, but consult doctor if persistent.
Dry mouth (Common (5-10%))
Sip water frequently, chew sugarless gum, or use saliva substitutes. Consult doctor if severe.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid alcohol. Consult doctor if persistent.
Blurred vision (Uncommon (1-5%))
Avoid driving. Usually temporary. Consult doctor if persistent.
Nausea (Uncommon (1-5%))
Take with food or milk. Consult doctor if severe or persistent.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, lips, or throat, difficulty breathing, or dizziness.
Liver damage (hepatotoxicity) (Rare (<0.1%) with normal doses; higher with overdose)
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, abdominal pain, or nausea. Do not exceed recommended dose.
Blood disorders (e.g., agranulocytosis, thrombocytopenia) (Very rare (<0.01%))
Consult doctor if you experience unusual bleeding, bruising, fever, or sore throat.
Seizures (Very rare (<0.01%))
Seek immediate medical attention if seizures occur.

⚠️ Rare Side Effects

Photosensitivity
Avoid excessive sun exposure and use sunscreen. Consult doctor if rash develops.
Urinary retention
Consult doctor if you have difficulty urinating, especially if you have prostate enlargement.
Palpitations
Consult doctor if you experience fast or irregular heartbeat.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Alcohol Major
Warfarin Moderate
Tricyclic antidepressants Moderate
Fluoxetine Moderate
Rifampicin Moderate
Antacids Minor
Activated charcoal Minor
CNS depressants Major
Caffeine Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Alcohol and other CNS depressants
  • Warfarin

⚡ Moderate Interactions

  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
  • CYP2D6 inhibitors (e.g., fluoxetine, quinidine)
  • CYP3A4 inducers (e.g., rifampicin, carbamazepine)

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and the risk of liver damage, especially with Paracetamol. Concurrent use may impair your ability to drive or operate machinery.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Chlorpheniramine Maleate, Paracetamol, or any component of the formulation","Newborns and premature infants","Nursing mothers","Severe liver disease or severe active liver disease","Severe kidney disease","Patients taking MAO inhibitors within 14 days","Narrow-angle glaucoma","Urinary retention or prostatic hypertrophy","Severe asthma or COPD"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","Do not exceed recommended dose of Paracetamol; risk of liver damage.","Use with caution in patients with liver or kidney disease.","Use with caution in elderly due to increased risk of confusion, constipation, and urinary retention.","Use with caution in children; may cause paradoxical excitation.","Consult doctor if symptoms persist beyond 7 days or if fever worsens.","Do not use for self-medication for more than 3 days without consulting a doctor."]

🤱 Lactation Safety

Chlorpheniramine Maleate and Paracetamol are excreted in breast milk. Caution is advised. Consult your doctor before use during breastfeeding.

💊 Overdose Management

Overdose can cause severe liver damage from Paracetamol and severe anticholinergic effects from Chlorpheniramine. Symptoms include nausea, vomiting, abdominal pain, confusion, seizures, and coma. Seek immediate medical attention. Treatment includes gastric lavage, activated charcoal, and administration of N-acetylcysteine for Paracetamol toxicity. Supportive care for Chlorpheniramine toxicity.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Avoid consuming alcohol or other central nervous system depressants while taking this medicine, as it can increase drowsiness and dizziness. Inform your doctor if you have liver or kidney disease, glaucoma, enlarged prostate, or breathing problems such as asthma or COPD. Do not use this medicine for longer than directed without medical advice. Keep out of reach of children. Store at room temperature away from moisture and heat. If you are pregnant or breastfeeding, consult your doctor before taking this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the side effects of Chlorpheniramine, such as drowsiness, confusion, dry mouth, constipation, and urinary retention. They may also be at higher risk of Paracetamol-induced liver toxicity. Use with caution and consider lower doses. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this combination during pregnancy has not been fully established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

After surgery, consult your doctor before taking this medicine. It may interact with anesthetics and other medications. Paracetamol may be used for pain relief, but Chlorpheniramine can increase sedation. Follow your surgeon's advice.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It may cause dry mouth and drowsiness. Your dentist may adjust your treatment plan accordingly.

💚 Lifestyle Tips for Better Results

🏃
Avoid known allergens such as dust, pollen, and pet dander.
🥗
Use air purifiers and keep windows closed during high pollen seasons.
😴
Maintain good hydration to help thin mucus.
💧
Get adequate rest to support your immune system.
🧘
Practice good hand hygiene to prevent infections.
🌞
Use a humidifier to ease nasal congestion.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness, which can impair your ability to exercise safely. Avoid strenuous exercise or activities requiring alertness until you know how the medicine affects you. Stay hydrated during exercise.

🥗 Diet Recommendations

Include foods rich in vitamin C such as oranges, lemons, and bell peppers to support immune function.
Consume warm fluids like soups and herbal teas to soothe a sore throat and congestion.
Avoid processed foods and excessive sugar, which can weaken the immune system.
Stay well hydrated by drinking plenty of water.
Include anti-inflammatory foods like ginger, turmeric, and fatty fish.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or perform tasks requiring mental alertness. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job involves operating heavy machinery.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it regularly for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended. Prolonged use of Paracetamol can lead to liver damage, especially at high doses. Chlorpheniramine may cause tolerance and dependence. Regular monitoring of liver function may be required if used for extended periods. Consult your doctor for alternative treatments if symptoms persist.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Helps clear nasal passages and reduce congestion without medication.

Evidence: Well-established
Allergen avoidance

Reducing exposure to allergens can prevent allergic symptoms.

Evidence: Well-established
Immunotherapy

Allergy shots can provide long-term relief for certain allergies.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination. It is safe to take this medicine before or after vaccination unless advised otherwise.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light and moisture. If crossing time zones, adjust dosing schedule accordingly, but do not exceed the maximum daily dose. Check customs regulations for carrying medications. Keep it in your carry-on luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergies
She experienced sneezing, runny nose, and itchy eyes every spring. Her doctor prescribed this medicine. She took one tablet every 6 hours as needed. Within 30 minutes, her symptoms improved significantly. She noted drowsiness, so she avoided driving. She was advised to take it only for a few days.
💡 Lesson: This medicine provides rapid relief from allergy symptoms but can cause drowsiness. Avoid driving and use only as directed.
👤 A 50-year-old man with common cold and fever
He had a cold with fever and body ache. He took this medicine as prescribed. His fever reduced and body ache relieved. He was cautioned not to exceed the dose due to Paracetamol content. He recovered within 3 days.
💡 Lesson: This medicine effectively reduces fever and pain associated with cold, but adherence to dosage limits is crucial to prevent liver damage.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 to 60 minutes after taking it.

Q: Can I take this medicine on an empty stomach?

A: It can be taken with or without food, but taking it with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is it safe to take this medicine during pregnancy?

A: Consult your doctor before taking this medicine during pregnancy. The safety has not been fully established.

Q: Can I take this medicine with alcohol?

A: No, avoid alcohol while taking this medicine as it can increase drowsiness and the risk of liver damage.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe for children?
  • Can I take it with other cold medicines?

🔄 Substitutes for anamol plus tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is safe for everyone.
    Fact: It is not safe for newborns, nursing mothers, and those with certain medical conditions. Consult a doctor.
  • Myth: It can be taken long-term without any risk.
    Fact: Prolonged use can cause liver damage and other side effects. Use only as directed.
  • Myth: It is a cure for allergies.
    Fact: It only provides symptomatic relief; it does not cure the underlying allergy.

🔄 Alternative Options

Generic Alternatives

  • Chlorpheniramine Maleate + Paracetamol tablet

Brand Alternatives

  • Anamol Plus Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Chlorpheniramine 4mg + Paracetamol 500mg","onset":"30-60 min","duration":"4-6 hours","sedation":"High"},{"medicine":"Cetirizine + Paracetamol","composition":"Cetirizine 5mg + Paracetamol 500mg","onset":"30-60 min","duration":"12-24 hours","sedation":"Low"},{"medicine":"Levocetirizine + Paracetamol","composition":"Levocetirizine 5mg + Paracetamol 500mg","onset":"30-60 min","duration":"12-24 hours","sedation":"Low"}]

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