Tritus  Tablet - Phenylpropanolamine (25mg) + Chlorpheniramine Maleate (4mg) medicine

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🏭 Burgeon Pharmaceuticals Pvt Ltd 📦 strip of 10 tablets 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of allergic rhinitis and common cold.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of the face, lips, tongue, or throat
  • Irregular or fast heartbeat
  • Seizures or convulsions
  • Severe dizziness or fainting
  • Inability to urinate
  • Yellowing of the skin or eyes
  • Severe headache with visual changes

If experiencing severe symptoms, call emergency services immediately.

What is Tritus Tablet used for?

This medicine is a combination of phenylpropanolamine (a decongestant) and chlorpheniramine maleate (an antihistamine) used to relieve nasal congestion, runny nose, sneezing, and itching due to allergies or common cold. It is for short-term use and may cause drowsiness.

  • Generic Name: Phenylpropanolamine (25mg) + Chlorpheniramine Maleate (4mg)
  • Manufacturer: Burgeon Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Tritus Tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी और सर्दी-जुकाम के लक्षणों जैसे नाक बंद होना, नाक बहना, छींक आना और खुजली को कम करने के लिए उपयोग की जाती है। इसमें फेनिलप्रोपेनॉलामाइन और क्लोरफेनिरामाइन मेलिएट होते हैं। यह नाक की भीड़ को कम करने और एलर्जी के लक्षणों को नियंत्रित करने में मदद करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, मुँह सूखना, धुंधली दृष्टि, मतली और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, अनियमित दिल की धड़कन, दौरे या पेशाब में रुकावट हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: दवा की खुराक से अधिक न लें। गाड़ी चलाने या मशीनरी चलाने से बचें जब तक आपको पता न चले कि यह दवा आप पर कैसे असर करती है। शराब न पिएं। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड, ग्लूकोमा या प्रोस्टेट की समस्या है तो डॉक्टर को बताएं। 7 दिनों से अधिक उपयोग न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 Tritus Tablet Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itching, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief of nasal congestion and rhinorrhea due to viral upper respiratory infections.","evidence":"Well-established"},{"condition":"Sinusitis","description":"Helps reduce nasal congestion and pressure in acute or chronic sinusitis.","evidence":"Limited"}]

Off-label uses: []

Primary treatment for: Allergic rhinitis

Also treats: Common cold, Sinusitis

📋 Drug Information

Generic Name(s)Phenylpropanolamine (25mg) + Chlorpheniramine Maleate (4mg)
Brand NameTritus Tablet
ManufacturerBurgeon Pharmaceuticals Pvt Ltd
Packaging / Formstrip of 10 tablets (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine exactly as prescribed by your doctor.
2
Avoid driving or operating heavy machinery until you know how this medicine affects you.
3
Do not drink alcohol while taking this medicine as it can increase drowsiness.
4
If you have high blood pressure, heart disease, or diabetes, inform your doctor before taking this medicine.
5
Do not use this medicine for more than 7 days without consulting a doctor.
6
Keep this medicine out of reach of children.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Nasal congestion
This medicine is commonly prescribed for this.
Likely Use
✅
Runny nose
This medicine helps reduce runny nose.
Likely Use
✅
Sneezing
This medicine helps control sneezing.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionPhenylpropanolamine and chlorpheniramine are absorbed from the gastrointestinal tract after oral administration. Exact bioavailability data for the combination syrup is not established from the available information.
DistributionBoth components are distributed widely throughout the body. Chlorpheniramine crosses the blood-brain barrier and may cause drowsiness. Protein binding information for the combination is not established from the available information.
Protein BindingNot established from the available information.
MetabolismPhenylpropanolamine is primarily metabolized in the liver. Chlorpheniramine is metabolized in the liver via cytochrome P450 enzymes, primarily CYP2D6. Specific metabolic data for the combination syrup is not established from the available information.
Half-LifeThe elimination half-life of phenylpropanolamine is approximately 3-4 hours. The elimination half-life of chlorpheniramine is approximately 12-43 hours. These values may vary based on individual factors.
ExcretionBoth phenylpropanolamine and chlorpheniramine are excreted primarily in the urine. The exact excretion profile for the combination syrup is not established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionOnset of action is typically within 30-60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations are generally reached within 1-2 hours for phenylpropanolamine and 2-6 hours for chlorpheniramine.
Duration of ActionThe duration of action is approximately 4-6 hours for phenylpropanolamine and 4-8 hours for chlorpheniramine, but this may vary.

How It Works

Phenylpropanolamine acts primarily as an alpha-adrenergic agonist, causing vasoconstriction of nasal mucosal blood vessels, which reduces swelling and congestion. Chlorpheniramine maleate is a first-generation histamine H1-receptor antagonist that competes with histamine for H1-receptor sites on effector cells, thereby reducing allergic symptoms such as sneezing, rhinorrhea, and itching.

Mechanism Steps

1
Alpha-adrenergic stimulation: Phenylpropanolamine stimulates alpha-adrenergic receptors on nasal blood vessels, leading to vasoconstriction and reduced nasal congestion.
2
Histamine H1 receptor blockade: Chlorpheniramine maleate competitively blocks histamine H1 receptors, preventing histamine-induced sneezing, itching, and increased vascular permeability.
3
Combined symptomatic relief: The combined actions reduce nasal stuffiness, runny nose, and allergic symptoms.

💡 How to Take Tritus Tablet

Strength: Each 5 mL contains Phenylpropanolamine 25 mg and Chlorpheniramine Maleate 4 mg.

1Shake the bottle well before use.
2Use a measuring cup or spoon to measure the dose accurately.
3Take orally with or without food.
4Follow the dosage instructions provided by your doctor.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is 5-10 mL (1-2 teaspoons) every 4-6 hours as needed, not to exceed 4 doses in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially drowsiness, dizziness, and anticholinergic effects. Use with caution and consult a doctor for appropriate dosing.
Renal ImpairmentDose adjustment may be required in patients with renal impairment. Consult a doctor.
Hepatic ImpairmentDose adjustment may be required in patients with hepatic impairment. Consult a doctor.
Maximum Daily DoseNot established from the available information. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases drowsiness and CNS depression.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Tritus Tablet

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If persistent, consult your doctor.
Dry mouth (Common (5-15%))
Sip water or chew sugarless gum. Consult doctor if severe.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid alcohol.
Nausea (Common (5-10%))
Take with food or milk. Consult doctor if persistent.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, lips, tongue, or throat, or difficulty breathing.
Irregular heartbeat (arrhythmia) (Rare (<0.1%))
Seek immediate medical attention if you feel palpitations, chest pain, or shortness of breath.
Seizures (Rare (<0.1%))
Seek immediate medical attention if you experience convulsions or loss of consciousness.
Hallucinations (Rare (<0.1%))
Seek immediate medical attention if you see or hear things that are not there.
Urinary retention (Rare (<0.1%))
Seek medical attention if you are unable to urinate.

⚠️ Rare Side Effects

Blood dyscrasias
Report unusual bleeding, bruising, or fatigue to your doctor.
Hepatotoxicity
Report yellowing of skin or eyes, dark urine, or abdominal pain to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Alcohol Moderate
Antihypertensives Moderate
Tricyclic antidepressants Moderate
CNS depressants Moderate

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Other sympathomimetics

⚡ Moderate Interactions

  • CNS depressants (alcohol, sedatives, tranquilizers)
  • Antihypertensives
  • Tricyclic antidepressants

🍷 Alcohol Interaction

Alcohol increases the sedative effects of chlorpheniramine and may enhance the central nervous system depression. Avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to phenylpropanolamine, chlorpheniramine, or any component of the formulation","Concurrent use with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping MAOIs","Uncontrolled hypertension","Severe coronary artery disease","Hyperthyroidism","Narrow-angle glaucoma","Urinary retention","Children under 12 years of age (unless directed by a doctor)"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","Use with caution in patients with cardiovascular disease, hypertension, diabetes, thyroid disorders, glaucoma, or prostate enlargement.","Do not exceed recommended dose.","Do not use for more than 7 days without consulting a doctor.","Keep out of reach of children.","If pregnant or breastfeeding, consult a doctor before use."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before use.

💊 Overdose Management

Overdose may cause severe drowsiness, dizziness, confusion, hallucinations, seizures, irregular heartbeat, or difficulty breathing. Seek immediate medical attention or contact a poison control center. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you. Do not drink alcohol while taking this medicine as it can increase drowsiness. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, glaucoma, or prostate enlargement. Do not use this medicine for more than 7 days without consulting a doctor. Keep out of reach of children. If you are pregnant or breastfeeding, consult your doctor before use.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of this medicine, especially drowsiness, dizziness, and anticholinergic effects. Use with caution and consult a doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding.

🏥 Post-Surgery Considerations

Consult your doctor before taking this medicine after surgery, as it may interact with other medications or affect recovery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and affect dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated to help thin mucus.
🥗
Use a humidifier to ease nasal congestion.
😴
Avoid allergens that trigger your symptoms.
💧
Get plenty of rest to support recovery.
🧘
Practice good hand hygiene to prevent infections.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel dizzy or drowsy. Consult your doctor before resuming exercise.

🥗 Diet Recommendations

Drink warm fluids like soup or tea.
Avoid alcohol and caffeine.
Eat a balanced diet rich in vitamins and minerals.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to tolerance, dependence, or increased risk of side effects. Regular monitoring by a doctor is advised if extended use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Can help relieve nasal congestion without medication.

Evidence: Well-established
Antihistamine nasal sprays

May be an alternative for allergic rhinitis.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergies
She was prescribed this medicine for her runny nose and sneezing. She took it as directed and found relief within an hour. She experienced mild drowsiness, so she avoided driving after taking it.
💡 Lesson: This medicine can provide quick relief from allergy symptoms, but it may cause drowsiness, so plan activities accordingly.
👤 A 50-year-old man with common cold
He used this medicine for his nasal congestion and sneezing. He noticed significant improvement in his symptoms but also experienced dry mouth. He sipped water frequently to manage it.
💡 Lesson: Dry mouth is a common side effect that can be managed by staying hydrated.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30-60 minutes after oral administration.

Q: Can I take this medicine with other medications?

A: Consult your doctor before taking this medicine with other medications, especially MAOIs, antihypertensives, or CNS depressants.

Q: Is it safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Tritus Tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine only provides symptomatic relief and does not cure the underlying infection.
  • Myth: It is safe to take this medicine for long periods.
    Fact: Prolonged use without medical supervision can lead to side effects and is not recommended.

📊 Comparison with Similar Medicines

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