Anatryl Plus Tablet: Complete Information on Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Yellowing of skin or eyes
- Dark urine
- Severe abdominal pain
- Difficulty breathing or swelling of face, lips, or throat
- Unusual bleeding or bruising
- Severe drowsiness or confusion
- Persistent fever for more than 3 days
If experiencing severe symptoms, call emergency services immediately.
What is cemol plus 500mg/4mg/60mg tablet used for?
This medicine is a combination of Paracetamol and Chlorpheniramine Maleate used to treat symptoms of common cold and allergies such as runny nose, sneezing, and mild fever. It works by reducing pain and fever and blocking histamine.
- Generic Name: Paracetamol + Chlorpheniramine Maleate
- Manufacturer: Casca Remedies Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cemol plus 500mg/4mg/60mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पैरासिटामोल और क्लोरफेनिरामाइन मेलिएट का संयोजन है, जिसका उपयोग सर्दी-जुकाम और एलर्जी के लक्षणों जैसे नाक बहना, छींक आना, आंखों में पानी आना और हल्के बुखार के इलाज के लिए किया जाता है। यह दर्द और बुखार को कम करने और हिस्टामिन को ब्लॉक करने में मदद करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि और पेट में परेशानी शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर एलर्जी प्रतिक्रिया, यकृत क्षति और रक्त विकार शामिल हो सकते हैं। यदि आपको पीलिया, गहरे रंग का मूत्र, गंभीर पेट दर्द या सांस लेने में कठिनाई हो तो तुरंत चिकित्सा सहायता लें।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें। शराब और अन्य नींद लाने वाली दवाओं से बचें क्योंकि इससे नींद और बढ़ सकती है। जब तक आपको पता न चले कि यह दवा आपको कैसे प्रभावित करती है, तब तक वाहन न चलाएं या भारी मशीनरी न चलाएं। यदि आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं या स्तनपान करा रही हैं तो अपने डॉक्टर को बताएं। बिना डॉक्टर की सलाह के 7 दिनों से अधिक इसका उपयोग न करें। बच्चों की पहुंच से दूर रखें।
💊 cemol plus 500mg/4mg/60mg tablet Uses & Benefits
[{"condition":"Common cold","description":"Relieves symptoms such as runny nose, sneezing, and mild fever associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Reduces sneezing, rhinorrhea, and itching of the nose and throat due to allergies.","evidence":"Well-established"},{"condition":"Upper respiratory tract allergy","description":"Provides symptomatic relief from allergic symptoms affecting the upper respiratory tract.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Mild pain with allergic component","description":"Sometimes used for pain relief when an allergic component is also present.","evidence":"Limited"}]
Primary treatment for: Common cold and allergic rhinitis
Also treats: Allergic rhinitis, Upper respiratory tract allergy
📋 Drug Information
| Generic Name(s) | Paracetamol + Chlorpheniramine Maleate |
| Brand Name | Anatryl Plus Tablet |
| Manufacturer | Casca Remedies Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antipyretic, Analgesic, Antihistamine |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which leads to pain relief and fever reduction. Chlorpheniramine Maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, thereby reducing allergic symptoms such as sneezing, runny nose, and itching. The combination provides both analgesic and antihistaminic effects.
Mechanism Steps
💡 How to Take cemol plus 500mg/4mg/60mg tablet
Strength: Tablet: Paracetamol 500 mg + Chlorpheniramine Maleate 4 mg
Dosage Information
| Adult Dosage | The usual adult dose is 1 tablet every 6 to 8 hours as needed for symptoms, not to exceed 4 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects, especially drowsiness and confusion. Use with caution and consult a doctor for appropriate dosing. |
| Renal Impairment | Dose adjustment may be required in patients with renal impairment. Consult a doctor. |
| Hepatic Impairment | Dose adjustment may be required in patients with hepatic impairment. Consult a doctor. |
| Maximum Daily Dose | Paracetamol: 4000 mg per day. Chlorpheniramine: 24 mg per day. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cemol plus 500mg/4mg/60mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Alcohol | Major | |
| Benzodiazepines | Major | |
| MAOIs | Moderate | |
| Tricyclic antidepressants | Moderate |
🚨 Major Interactions
- Warfarin
- Alcohol
- CNS depressants (e.g., benzodiazepines, opioids)
⚡ Moderate Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants
🍷 Alcohol Interaction
Avoid alcohol consumption while taking this medicine as it can increase the risk of liver damage and enhance drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to paracetamol, chlorpheniramine, or any component of the formulation","Severe liver disease","Narrow-angle glaucoma","Urinary retention","Asthma","Breastfeeding"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Do not use for more than 7 days without consulting a doctor.","Use with caution in patients with liver or kidney disease.","Use with caution in elderly patients due to increased risk of confusion and falls.","Consult doctor if pregnant or planning to become pregnant."]
🤱 Lactation Safety
Paracetamol is considered safe during breastfeeding. Chlorpheniramine may pass into breast milk and cause drowsiness in the infant. Consult your doctor before use.
💊 Overdose Management
Overdose may cause severe liver damage, nausea, vomiting, and abdominal pain. Seek immediate medical attention. Treatment includes activated charcoal, N-acetylcysteine, and supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid alcohol and other central nervous system depressants as they can increase drowsiness. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use for more than 7 days without consulting a doctor. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to side effects such as drowsiness, confusion, and falls. Use with caution and consider lower doses. Consult a doctor before use.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are planning to become pregnant. Paracetamol is generally considered safe, but chlorpheniramine should be used with caution.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, as it may interact with other medications or affect recovery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with anesthetics or other medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while taking this medicine, especially if you feel drowsy or dizzy. Light activity like walking may be fine if you feel up to it.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job requires alertness.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use of paracetamol can increase the risk of liver damage, especially with high doses or alcohol consumption. Chlorpheniramine may cause tolerance and dependence. Regular monitoring of liver function may be required if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help relieve nasal congestion without medication.
Evidence: Well-establishedAlternative for allergic rhinitis with fewer systemic side effects.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30-60 minutes after oral administration.
A: It can be taken with or without food, but taking it with food may reduce stomach upset.
A: It is intended for short-term use. Consult your doctor if you need it for more than 7 days.
🤔 Common Patient Concerns
🔄 Substitutes for cemol plus 500mg/4mg/60mg tablet
View AllAlternative brands with exact same active ingredient:
-
care flu 4mg/500mg tabletTOSC International Pvt Ltd ₹7.97 41.4% CHEAPER
-
cap tabletSymet Drugs Ltd ₹11.25 17.3% CHEAPER
-
sudohist p tabletHamax Pharmaceuticals ₹11.25 17.3% CHEAPER
-
anamol plus tabletAngel Laboratories Pvt Ltd ₹14.00 2.9% COSTLIER
-
anatryl plus tabletAan Pharma Pvt Ltd ₹15.00 10.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine only provides symptomatic relief; it does not cure the underlying viral infection. - Myth: It is safe to take more than the recommended dose.
Fact: Exceeding the recommended dose can cause severe liver damage.
🔄 Alternative Options
Generic Alternatives
- Paracetamol + Chlorpheniramine Maleate combination tablets
Brand Alternatives
- Anatryl Plus Tablet