allegra-m tablet - Montelukast (10mg) + Fexofenadine (120mg) medicine

allegra-m tablet

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🏭 Sanofi India Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
🤰 Pregnancy Category B 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

What is allegra-m tablet used for?

This medicine contains Montelukast (10mg) + Fexofenadine (120mg) and is used to treat RESPIRATORY. Montelukast blocks leukotriene receptors, reducing airway inflammation. Fexofenadine blocks H1 hista. Always consult your doctor before use.

  • Generic Name: Montelukast + Fexofenadine
  • Manufacturer: Sanofi India Ltd
  • Form: Allopathy
  • Pregnancy Category: Category B
  • Prescription Required: Yes
💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 allegra-m tablet Uses & Benefits

Allergic rhinitis, asthma, chronic urticaria

Off-label uses: Exercise-induced bronchoconstriction, chronic idiopathic urticaria

📋 Drug Information

Generic Name(s)Montelukast + Fexofenadine
Brand NameAllegra-M
ManufacturerSanofi India Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassLeukotriene Receptor Antagonist + Antihistaminic
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMontelukast: Rapidly absorbed; Fexofenadine: Rapidly absorbed
DistributionWidely distributed; Fexofenadine does not cross BBB
Protein BindingMontelukast: 99%; Fexofenadine: 60-70%
MetabolismMontelukast: Hepatic (CYP3A4, 2C9); Fexofenadine: Minimal hepatic
Half-LifeMontelukast: 2.7-5.5 hours; Fexofenadine: 14.4 hours
ExcretionMontelukast: Biliary; Fexofenadine: Feces (80%), Urine (10%)
BioavailabilityMontelukast: 64%; Fexofenadine: 30-40%
Onset of ActionMontelukast: 1-3 hours; Fexofenadine: 1 hour
Peak Plasma TimeMontelukast: 3-4 hours; Fexofenadine: 1-3 hours
Duration of ActionMontelukast: 24 hours; Fexofenadine: 24 hours

How It Works

Montelukast blocks leukotriene receptors, reducing airway inflammation. Fexofenadine blocks H1 histamine receptors, reducing allergy symptoms.

Mechanism Steps

1Montelukast blocks CysLT1 receptors
2Reduces eosinophil infiltration
3Fexofenadine blocks H1 receptors
4Reduces histamine-mediated symptoms

💡 How to Take allegra-m tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of allegra-m tablet

✅ Common Side Effects

Headache
Drowsiness
Nausea
Dry mouth

🚨 Serious Side Effects

Anaphylaxis
Severe allergic reactions

⚠️ Rare Side Effects

Behavioral changes (montelukast)
Thrombocytopenia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
CYP3A4 inhibitors Major Increased montelukast levels
Antacids Major Decreased fexofenadine absorption

🚨 Major Interactions

  • CYP3A4 inhibitors (montelukast)
  • Antacids (fexofenadine)

⚡ Moderate Interactions

  • Phenobarbital
  • Rifampin

🍷 Alcohol Interaction

May increase drowsiness; avoid concurrent use

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to montelukast or fexofenadine

🤱 Lactation Safety

Use with caution; excreted in breast milk

💊 Overdose Management

Supportive care; monitor for cardiac effects

⏰ Missed Dose

Take as soon as remembered unless near next dose

🔄 Substitutes for allegra-m tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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