allegone cold tablet - Caffeine (30mg) + Paracetamol (500mg) medicine

Ancer Tablet: Complete Medicine Guide

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🏭 Agron Remedies Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for paracetamol; caffeine as adjuvant has moderate evidence.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of skin or eyes
  • Severe abdominal pain
  • Dark urine
  • Difficulty breathing
  • Swelling of face, lips, or throat
  • Unusual bleeding or bruising
  • Persistent vomiting

If experiencing severe symptoms, call emergency services immediately.

What is allegone cold tablet used for?

This medicine is a combination of caffeine and paracetamol used for mild to moderate pain and fever. It works by reducing pain and fever, with caffeine enhancing the effect of paracetamol.

  • Generic Name: Caffeine + Paracetamol
  • Manufacturer: Agron Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 allegone cold tablet के बारे में (Hindi Summary)

उपयोग: यह दवा कैफीन और पैरासिटामोल का संयोजन है, जिसका उपयोग हल्के से मध्यम दर्द और बुखार के इलाज के लिए किया जाता है। यह सिरदर्द, दांत दर्द, मांसपेशियों में दर्द, मासिक धर्म में ऐंठन और बुखार से राहत दिलाने में मदद करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में बेचैनी, अनिद्रा, घबराहट, मतली और पेट में परेशानी शामिल हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें त्वचा की गंभीर प्रतिक्रियाएं, यकृत की क्षति और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं।

सुरक्षा सलाह: अनुशंसित खुराक से अधिक न लें। पैरासिटामोल युक्त अन्य उत्पादों के साथ न लें। इस दवा को लेते समय शराब का सेवन सीमित करें। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको यकृत या गुर्दे की समस्या है तो डॉक्टर से परामर्श लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 allegone cold tablet Uses & Benefits

[{"condition":"Tension headache","description":"Relieves mild to moderate headache pain.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces elevated body temperature.","evidence":"Well-established"},{"condition":"Musculoskeletal pain","description":"Provides relief from minor aches and pains of muscles and joints.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Helps alleviate menstrual cramps.","evidence":"Well-established"},{"condition":"Toothache","description":"Provides temporary relief from dental pain.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Pain and fever

Also treats: Headache, Musculoskeletal pain, Dysmenorrhea, Toothache

📋 Drug Information

Generic Name(s)Caffeine + Paracetamol
Brand NameAcolate Tablet
ManufacturerAgron Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAnalgesic and Antipyretic Combination
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Do not exceed the recommended dose to avoid liver damage.
3
Avoid alcohol while taking this medicine.
4
Consult your doctor if pain or fever persists beyond 3 days.
5
Do not take other paracetamol-containing products concurrently.
6
Stay hydrated while taking this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Headache
This medicine is commonly used for headache relief.
Likely Use
✅
Fever
This medicine helps reduce fever.
Likely Use
❌
Chest pain
This medicine is not for chest pain; seek immediate medical help.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionParacetamol is rapidly and completely absorbed from the gastrointestinal tract. Caffeine is also rapidly absorbed. Food may delay absorption slightly.
DistributionParacetamol distributes widely into body tissues. Caffeine distributes throughout body water.
Protein BindingParacetamol: 10-25%. Caffeine: 10-35%.
MetabolismParacetamol is metabolized in the liver primarily via glucuronidation and sulfation, with a small fraction via CYP2E1 to NAPQI. Caffeine is metabolized in the liver by CYP1A2.
Half-LifeParacetamol: 2-3 hours. Caffeine: 3-7 hours.
ExcretionParacetamol metabolites are excreted in urine. Caffeine metabolites are excreted in urine.
BioavailabilityParacetamol: 80-100%. Caffeine: nearly 100%.
Onset of ActionParacetamol: 30-60 minutes. Caffeine: 15-45 minutes.
Peak Plasma TimeParacetamol: 0.5-2 hours. Caffeine: 0.5-2 hours.
Duration of ActionParacetamol: 4-6 hours. Caffeine: 3-5 hours.

How It Works

Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which reduces pain and fever. Caffeine is a central nervous system stimulant that constricts cerebral blood vessels and may enhance the analgesic effect of paracetamol by increasing its bioavailability or modulating pain perception.

Mechanism Steps

1
Paracetamol central action: Paracetamol inhibits prostaglandin synthesis in the central nervous system, reducing pain and fever.
2
Caffeine adenosine antagonism: Caffeine blocks adenosine receptors, leading to increased neuronal activity and vasoconstriction.
3
Enhanced analgesia: Caffeine may enhance the analgesic effect of paracetamol by increasing its central nervous system penetration or by modulating pain pathways.

💡 How to Take allegone cold tablet

Strength: Tablet containing Caffeine 30 mg and Paracetamol 500 mg.

1Take this medicine by mouth with a full glass of water.
2Take with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Follow the dosage instructions on the label or as prescribed by your doctor.
5Do not take more than the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is 1 tablet every 4 to 6 hours as needed for pain or fever, not to exceed 6 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to side effects. Use with caution and consult a doctor for appropriate dosing.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose reduction or avoidance may be necessary. Consult a doctor.
Maximum Daily DoseMaximum daily dose is 6 tablets (3000 mg paracetamol and 180 mg caffeine) in 24 hours. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase caffeine levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of allegone cold tablet

✅ Common Side Effects

Nausea (Common (1-10%))
Take with food to reduce nausea. Consult doctor if persistent.
Insomnia (Common (1-10%))
Avoid taking close to bedtime. Consult doctor if severe.
Restlessness (Common (1-10%))
Usually temporary. Reduce dose if bothersome after consulting doctor.
Stomach discomfort (Common (1-10%))
Take with food or milk. Consult doctor if persists.

🚨 Serious Side Effects

Liver damage (Rare (<0.1%))
Seek immediate medical attention if you experience yellowing of skin or eyes, dark urine, or severe abdominal pain.
Severe allergic reaction (Rare (<0.1%))
Stop medicine and seek emergency help if you have rash, swelling, or difficulty breathing.
Severe skin reactions (Very rare (<0.01%))
Discontinue and seek immediate medical attention if you develop blistering or peeling skin.

⚠️ Rare Side Effects

Blood disorders
Consult doctor if you notice unusual bruising or bleeding.
Pancreatitis
Seek medical attention if severe abdominal pain radiating to back occurs.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Carbamazepine Moderate
Phenytoin Moderate
Rifampicin Moderate
Cimetidine Minor
Oral contraceptives Minor

🚨 Major Interactions

  • Warfarin
  • Alcohol
  • Other paracetamol-containing products

⚡ Moderate Interactions

  • Carbamazepine
  • Phenytoin
  • Rifampicin

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine as it increases the risk of liver damage, especially with paracetamol. It may also increase caffeine-related side effects such as insomnia and restlessness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to paracetamol or caffeine","Severe liver disease","Severe kidney disease","Alcoholism"]

⚠️ Warnings & Precautions

["Do not exceed recommended dose.","Avoid alcohol.","Consult doctor if pregnant or breastfeeding.","Use with caution in patients with liver or kidney disease.","May cause drowsiness or dizziness; avoid driving if affected."]

🤱 Lactation Safety

Paracetamol and caffeine are excreted in breast milk in small amounts. Use with caution and consult your doctor.

💊 Overdose Management

Overdose can cause severe liver damage. Seek immediate medical attention even if you feel well. Treatment may include activated charcoal, N-acetylcysteine, and supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Do not exceed the recommended dose. Avoid taking this medicine with other paracetamol-containing products to prevent accidental overdose. Limit alcohol consumption while taking this medicine, as it may increase the risk of liver damage. Consult your doctor if you are pregnant, breastfeeding, or have liver or kidney problems. Do not use for more than 3 days for fever or 10 days for pain without medical advice. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of caffeine and paracetamol. Use with caution and consult a doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are planning to become pregnant. Paracetamol is generally considered safe, but caffeine intake should be limited.

🏥 Post-Surgery Considerations

Consult your surgeon or doctor before taking this medicine after surgery, as it may interact with other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated by drinking plenty of water.
🥗
Get adequate rest to help your body recover.
😴
Avoid alcohol while taking this medicine.
💧
Maintain a healthy diet rich in fruits and vegetables.
🧘
Manage stress through relaxation techniques.

🏋️ Exercise Considerations

This medicine may cause dizziness or drowsiness in some people. Avoid strenuous exercise or driving if you feel affected.

🥗 Diet Recommendations

Include foods rich in antioxidants.
Avoid fatty and processed foods.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or dizziness in some individuals. Avoid driving or operating heavy machinery until you know how it affects you.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms persist beyond 3 days for fever or 10 days for pain, or if you experience any serious side effects.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of liver damage, especially with high doses or alcohol consumption. Regular monitoring of liver function may be required. Consult your doctor for prolonged use.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can help manage chronic pain conditions.

Evidence: Well-established
Relaxation techniques

May help reduce tension headaches.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. No time zone adjustments are needed for this medicine. Check customs regulations for carrying medications across borders.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with tension headache
She took this medicine as directed and experienced relief within 45 minutes. She noted that taking it with a snack helped prevent nausea.
💡 Lesson: Taking with food can improve tolerability.
👤 A 50-year-old man with fever and body ache
He used this medicine for two days and his fever subsided. He was advised not to exceed the dose and to avoid alcohol.
💡 Lesson: Short-term use as directed is effective and safe for most people.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 to 60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best to take it with food or milk to reduce stomach upset.

Q: Is it safe to take with other pain relievers?

A: Consult your doctor before combining with other pain relievers, especially those containing paracetamol.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my liver?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for allegone cold tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is safe to take with other paracetamol products.
    Fact: No, taking multiple paracetamol-containing products can lead to overdose and liver damage.
  • Myth: This medicine can be taken on an empty stomach without issues.
    Fact: It is better to take with food to reduce stomach upset.

🔄 Alternative Options

Generic Alternatives

  • Caffeine 30 mg + Paracetamol 500 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Caffeine 30 mg + Paracetamol 500 mg","uses":"Pain and fever","onset":"30-60 minutes"},{"medicine":"Paracetamol 500 mg","composition":"Paracetamol 500 mg","uses":"Pain and fever","onset":"30-60 minutes"},{"medicine":"Ibuprofen 400 mg","composition":"Ibuprofen 400 mg","uses":"Pain, fever, inflammation","onset":"30-60 minutes"}]

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