pilcold tablet - Caffeine (30mg) + Paracetamol (500mg) medicine

Imol Cold M 500 Tablet: Complete Medicine Guide

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🏭 Psychotropics India Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for paracetamol; caffeine as adjuvant has moderate evidence.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of skin or eyes
  • Severe abdominal pain
  • Dark urine
  • Blood in vomit or stool
  • Difficulty breathing or swelling of face
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is pilcold tablet used for?

This medicine is a combination of Paracetamol 500 mg and Caffeine 30 mg used for relief of mild to moderate pain and fever. It works by reducing pain and fever, with caffeine enhancing the effect.

  • Generic Name: Caffeine (30mg) + Paracetamol (500mg)
  • Manufacturer: Psychotropics India Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 pilcold tablet के बारे में (Hindi Summary)

उपयोग: यह दवा पैरासिटामोल और कैफीन का संयोजन है, जिसका उपयोग हल्के से मध्यम दर्द और बुखार के इलाज के लिए किया जाता है। यह सिरदर्द, दांत दर्द, मांसपेशियों के दर्द और मासिक धर्म के दर्द में राहत देती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, पेट दर्द, अनिद्रा, बेचैनी और घबराहट शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यकृत की क्षति, गंभीर त्वचा प्रतिक्रियाएं और एलर्जी हो सकती हैं।

सुरक्षा सलाह: अनुशंसित खुराक से अधिक न लें। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे यकृत की क्षति का खतरा बढ़ जाता है। बिना डॉक्टर की सलाह के 7 दिनों से अधिक उपयोग न करें। यदि आपको यकृत या गुर्दे की बीमारी है, या आप गर्भवती या स्तनपान करा रही हैं, तो अपने डॉक्टर को बताएं।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 pilcold tablet Uses & Benefits

[{"condition":"Headache","description":"Relieves tension headaches and mild migraine pain.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever associated with common colds and infections.","evidence":"Well-established"},{"condition":"Musculoskeletal pain","description":"Provides relief from mild to moderate muscle and joint pain.","evidence":"Well-established"},{"condition":"Toothache","description":"Temporarily relieves dental pain.","evidence":"Well-established"},{"condition":"Menstrual cramps","description":"Eases dysmenorrhea-related pain.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Post-vaccination pain","description":"Sometimes used to relieve pain and fever after vaccinations.","evidence":"Limited"}]

Primary treatment for: Pain and fever

Also treats: Headache, Musculoskeletal pain, Toothache, Menstrual cramps

📋 Drug Information

Generic Name(s)Caffeine (30mg) + Paracetamol (500mg)
Brand Namepilcold tablet
ManufacturerPsychotropics India Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) away from direct sunlight and moisture.
Shelf Life24 months from date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Do not exceed the recommended dose to avoid liver damage.
3
Avoid alcohol while taking this medicine.
4
Consult your doctor if pain persists beyond 7 days.
5
Do not take other paracetamol-containing products simultaneously.
6
Stay hydrated while taking this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Headache
This medicine is commonly used for headache relief.
Likely Use
Fever
This medicine helps reduce fever.
Likely Use
Chronic joint pain
This medicine is for short-term pain relief, not chronic conditions.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionParacetamol is rapidly and completely absorbed from the gastrointestinal tract. Caffeine is also rapidly absorbed.
DistributionParacetamol distributes widely into body tissues; caffeine distributes throughout body water.
Protein BindingParacetamol: 10-25%; Caffeine: 10-35%.
MetabolismParacetamol is metabolized in the liver via glucuronidation and sulfation; a small fraction is oxidized by CYP2E1 to NAPQI. Caffeine is metabolized in the liver by CYP1A2.
Half-LifeParacetamol: 2-3 hours; Caffeine: 3-7 hours.
ExcretionParacetamol metabolites are excreted in urine. Caffeine metabolites are excreted in urine.
BioavailabilityParacetamol: 80-100%; Caffeine: nearly 100%.
Onset of ActionParacetamol: 30-60 minutes; Caffeine: 15-45 minutes.
Peak Plasma TimeParacetamol: 0.5-2 hours; Caffeine: 0.5-2 hours.
Duration of ActionParacetamol: 4-6 hours; Caffeine: 3-5 hours.

How It Works

Paracetamol inhibits prostaglandin synthesis in the central nervous system, primarily through COX-2 inhibition, leading to reduced pain and fever. Caffeine acts as an adjuvant by blocking adenosine receptors, causing vasoconstriction and enhancing the analgesic effect of paracetamol.

Mechanism Steps

1
Paracetamol action: Paracetamol inhibits prostaglandin synthesis in the brain and spinal cord, reducing pain perception and fever.
2
Caffeine action: Caffeine blocks adenosine receptors, leading to vasoconstriction and increased alertness, and potentiates paracetamol's analgesic effect.

💡 How to Take pilcold tablet

Strength: Tablet: Paracetamol 500 mg + Caffeine 30 mg

1Take this medicine orally with a glass of water.
2Take with food to reduce stomach upset.
3Do not crush or chew the tablet; swallow whole.
4Follow the dosage instructions on the label or as prescribed by your doctor.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is 1-2 tablets every 4-6 hours as needed for pain or fever, not to exceed 8 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to side effects. Use with caution and consult doctor for dose adjustment.
Renal ImpairmentUse with caution in renal impairment. Dose adjustment may be needed. Consult doctor.
Hepatic ImpairmentUse with caution in hepatic impairment. Dose reduction may be necessary. Consult doctor.
Maximum Daily DoseParacetamol: 4000 mg per day. Caffeine: 240 mg per day (from this medicine).

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of liver damage.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of pilcold tablet

✅ Common Side Effects

Nausea (Common (1-10%))
Take with food to reduce nausea. Consult doctor if persistent.
Insomnia (Common (1-10%))
Avoid taking close to bedtime. Consult doctor if severe.
Restlessness (Common (1-10%))
Usually temporary. Reduce dose if bothersome after consulting doctor.
Stomach pain (Common (1-10%))
Take with food or milk. Consult doctor if severe.

🚨 Serious Side Effects

Liver damage (Rare (<0.1%))
Seek immediate medical attention if you experience yellowing of eyes or skin, dark urine, or severe abdominal pain.
Severe skin reactions (Very rare (<0.01%))
Stop medicine and seek immediate medical help if you develop rash, blisters, or peeling skin.
Anaphylaxis (Very rare (<0.01%))
Call emergency services if you have difficulty breathing, swelling of face, lips, or throat.

⚠️ Rare Side Effects

Thrombocytopenia
Report unusual bleeding or bruising to doctor immediately.
Agranulocytosis
Seek medical attention if you develop fever, sore throat, or mouth ulcers.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Carbamazepine Moderate
Phenytoin Moderate
Cimetidine Minor

🚨 Major Interactions

  • Warfarin
  • Alcohol

⚡ Moderate Interactions

  • Carbamazepine
  • Phenytoin

🍷 Alcohol Interaction

Avoid alcohol consumption while taking this medicine as it increases the risk of liver damage and may worsen side effects.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe liver disease","Hypersensitivity to paracetamol or caffeine","Alcoholism"]

⚠️ Warnings & Precautions

["Do not exceed recommended dose.","Avoid alcohol.","Use with caution in liver or kidney disease.","Consult doctor if symptoms persist beyond 7 days.","Not for children under 12 years without medical advice."]

🤱 Lactation Safety

Paracetamol and caffeine are excreted in breast milk in small amounts. Consult your doctor before use.

💊 Overdose Management

Seek immediate medical attention. Overdose can cause severe liver damage. Treatment includes activated charcoal, N-acetylcysteine, and supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Do not exceed the recommended dose. Avoid alcohol while taking this medicine as it increases the risk of liver damage. Do not use for more than 7 days without consulting a doctor. Inform your doctor if you have liver or kidney disease, or if you are pregnant or breastfeeding. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of caffeine and paracetamol. Use with caution and consult a doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are planning to become pregnant or are pregnant. Paracetamol is generally considered safe, but caffeine should be limited.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain relief as directed by your surgeon. Do not exceed the recommended dose.

🦷 Dental Procedures

This medicine can be taken for dental pain before or after procedures. Inform your dentist if you are taking it.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints.
🥗
Stay hydrated by drinking plenty of water.
😴
Get adequate rest and sleep.
💧
Manage stress through relaxation techniques.
🧘
Avoid alcohol and smoking.

🏋️ Exercise Considerations

Avoid strenuous exercise if you are taking this medicine for pain. Consult your doctor before starting any exercise routine.

🥗 Diet Recommendations

Include fruits and vegetables rich in antioxidants.
Limit caffeine intake from other sources.
Avoid alcohol.
Stay hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms persist beyond 7 days, if you experience any serious side effects, or if you develop signs of liver problems such as yellowing of eyes or skin.

📅 Long-Term Use Effects

Long-term use of this medicine can increase the risk of liver damage, especially with high doses or alcohol consumption. Regular monitoring of liver function may be needed if used for extended periods. Consult your doctor for alternative pain management if needed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can help manage chronic pain conditions.

Evidence: Well-established
Relaxation techniques

May help reduce tension headaches.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. It can be taken before or after vaccination if needed for pain or fever.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from moisture. When traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with tension headaches
She took this medicine as directed for her headaches. She found relief within 30 minutes and was able to continue her daily activities. She was advised to take it with food to avoid stomach upset.
💡 Lesson: Taking this medicine with food improves tolerability and provides effective pain relief.
👤 A 50-year-old man with fever and body ache
He used this medicine for fever and body pain. His fever subsided within an hour, and he felt more comfortable. He was reminded not to exceed the recommended dose and to avoid alcohol.
💡 Lesson: This medicine effectively reduces fever and pain when used as directed, but adherence to dosage limits is crucial.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30-60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best taken with food to reduce stomach upset.

Q: Is it safe for children?

A: It is not recommended for children under 12 years without medical advice.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for pilcold tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: It is safe to take more than the recommended dose.
    Fact: Taking more than the recommended dose can cause severe liver damage.
  • Myth: It can be taken with alcohol.
    Fact: Alcohol increases the risk of liver damage and should be avoided.

🔄 Alternative Options

Generic Alternatives

  • Paracetamol + Caffeine tablets

Brand Alternatives

  • Imol Cold M 500 Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Paracetamol 500 mg","difference":"Lacks caffeine, may be less effective for some headaches."},{"medicine":"Ibuprofen 400 mg","difference":"NSAID, different side effect profile, not for those with stomach ulcers."}]

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