Admox Plus 500mg/8mg Capsule: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Severe or bloody diarrhoea, or diarrhoea with fever and abdominal cramps.
- Yellowing of the skin or eyes, dark urine, or severe fatigue.
- A painful skin rash with blisters or peeling, or sores in the mouth or eyes.
- Seizures, confusion, or unusual muscle twitching.
- Decreased urine output or swelling in the legs.
- Unusual bruising or bleeding.
- Chest pain or palpitations.
If experiencing severe symptoms, call emergency services immediately.
What is Trimox BX 500mg/8mg Tablet used for?
This medicine is a combination of Amoxycillin 500 mg and Bromhexine 8 mg used to treat bacterial respiratory infections with thick mucus. Amoxycillin kills bacteria, while Bromhexine thins mucus. It is taken by mouth, usually two to three times a day, and must be prescribed by a doctor.
- Generic Name: Amoxycillin (500mg) + Bromhexine (8mg)
- Manufacturer: Mapra Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Trimox BX 500mg/8mg Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एमोक्सिसिलिन 500 मिलीग्राम और ब्रोमहेक्सिन 8 मिलीग्राम का संयोजन है। यह बैक्टीरियल श्वसन संक्रमण जैसे ब्रोंकाइटिस, निमोनिया और गले के संक्रमण में उपयोग की जाती है। एमोक्सिसिलिन बैक्टीरिया को मारता है और ब्रोमहेक्सिन बलगम को पतला करके निकालने में मदद करता है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और त्वचा पर चकत्ते शामिल हैं। कुछ लोगों को सिरदर्द या चक्कर आ सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई, या गंभीर दस्त हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। दवा को भोजन के साथ लेने से पेट की परेशानी कम होती है। पर्याप्त पानी पिएं। शराब न पिएं। अगर आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको किडनी या लिवर की बीमारी है, तो डॉक्टर को बताएं। यह दवा दूसरों के साथ साझा न करें।
💊 Trimox BX 500mg/8mg Tablet Uses & Benefits
[{"condition":"Acute bacterial bronchitis","description":"Used to treat bacterial infection of the large airways, helping to clear infection and loosen thick mucus.","evidence":"Well-established for the antibiotic component; mucolytic benefit is supportive."},{"condition":"Acute exacerbation of chronic bronchitis","description":"Prescribed when chronic bronchitis flares up with increased sputum and bacterial infection.","evidence":"Well-established for the antibiotic component; mucolytic benefit is supportive."},{"condition":"Community-acquired pneumonia (mild to moderate)","description":"May be used in selected patients to treat bacterial pneumonia while helping to clear secretions.","evidence":"Established for amoxycillin; combination with bromhexine is common in practice."},{"condition":"Productive cough with thick mucus due to bacterial respiratory infection","description":"Bromhexine thins mucus while amoxycillin treats the underlying bacterial cause.","evidence":"Supportive; mucolytics are used as adjuncts."}]
Off-label uses: [{"condition":"Sinusitis with thick secretions","description":"Occasionally prescribed when bacterial sinusitis is accompanied by very thick mucus.","evidence":"Limited"},{"condition":"Otitis media with thick effusion","description":"Rarely used in adults for middle ear infection with thick fluid, but not a standard first choice.","evidence":"Limited"}]
Primary treatment for: Bacterial respiratory tract infections
Also treats: Acute bronchitis, Chronic bronchitis exacerbation, Community-acquired pneumonia, Productive cough with thick mucus
📋 Drug Information
| Generic Name(s) | Amoxycillin (500mg) + Bromhexine (8mg) |
| Brand Name | Trimox BX 500mg/8mg Tablet |
| Manufacturer | Mapra Laboratories Pvt Ltd |
| Packaging / Form | strip of 10 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Keep away from direct sunlight, moisture, and heat. Do not refrigerate unless specifically instructed. Keep in the original container with the lid tightly closed. |
| Shelf Life | Typically 24 months from the date of manufacture. Check the expiry date on the pack before use. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different actions. Amoxycillin is a beta-lactam antibiotic that binds to penicillin-binding proteins on susceptible bacteria and blocks the cross-linking of peptidoglycan in the bacterial cell wall. This weakens the cell wall and causes the bacteria to burst and die. Bromhexine is a mucolytic that reduces the viscosity of mucus by breaking down acidic mucopolysaccharide fibres in bronchial secretions. It also stimulates the production of thinner serous mucus, making it easier to cough up. The combination helps treat the bacterial infection while simultaneously clearing the airways of thick secretions.
Mechanism Steps
💡 How to Take Trimox BX 500mg/8mg Tablet
Strength: Capsule containing Amoxycillin 500 mg and Bromhexine 8 mg, immediate release.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one capsule taken two to three times a day, depending on the severity of the infection and your doctor's assessment. The exact dose and duration must be individualized by a qualified clinician based on the indication, your age, weight, kidney and liver function, and other medicines you are taking. Do not self-adjust the dose. Always complete the full course prescribed. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may need a lower dose if kidney function is reduced. Kidney function should be checked before prescribing. The dose must be individualized by a qualified clinician based on renal function and other health conditions. |
| Renal Impairment | In patients with kidney impairment, the dose of amoxycillin may need to be reduced or the dosing interval lengthened. The exact adjustment depends on the degree of renal impairment and must be determined by a qualified clinician. Bromhexine dose adjustment in renal impairment is not well established. |
| Hepatic Impairment | In patients with liver impairment, this medicine should be used with caution. Amoxycillin is partly metabolised in the liver, and bromhexine undergoes extensive liver metabolism. Dose adjustment may be needed, and liver function should be monitored. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose of amoxycillin is usually 3 grams per day for adults, but the exact limit depends on the indication and kidney function. The maximum daily dose of bromhexine is not established from the available information. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Trimox BX 500mg/8mg Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Allopurinol | Major | |
| Oral contraceptives | Moderate | |
| Probenecid | Moderate | |
| Tetracyclines | Moderate | |
| Antacids | Minor | |
| Laxatives | Minor |
🚨 Major Interactions
- Warfarin
- Methotrexate
- Allopurinol
⚡ Moderate Interactions
- Oral contraceptives
- Probenecid
- Tetracyclines
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of stomach upset, nausea, and dizziness. It may also worsen dehydration, which is already a concern during respiratory infections. There is no specific chemical interaction between alcohol and amoxycillin or bromhexine, but the combination can make you feel worse and slow your recovery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to amoxycillin, other penicillins, or bromhexine.","History of severe allergic reaction to cephalosporins.","Severe liver disease.","Severe kidney disease without medical supervision.","Infectious mononucleosis (can cause severe rash).","Children under 12 years unless specifically prescribed by a pediatrician."]
⚠️ Warnings & Precautions
["Do not use for viral infections like the common cold or flu.","Complete the full course even if you feel better.","Tell your doctor if you have kidney or liver problems.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Avoid alcohol while taking this medicine.","Do not share this medicine with others.","Stop and seek medical help if you develop a severe rash, swelling, or difficulty breathing.","Watch for watery diarrhoea, which may indicate a serious gut infection.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Keep out of reach of children."]
🤱 Lactation Safety
Amoxycillin passes into breast milk in small amounts and is usually considered safe during breastfeeding. Bromhexine may also pass into breast milk, but the amount is not well established. Consult your doctor before using this medicine while breastfeeding. Watch for diarrhoea or thrush in the nursing infant.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, diarrhoea, and stomach pain. In severe cases, amoxycillin can cause seizures, especially in people with kidney disease. If you suspect an overdose, contact your doctor or a poison control centre immediately. Do not try to vomit unless instructed by a medical professional. Treatment is supportive and may include activated charcoal if taken recently. Dialysis may be considered in severe cases with kidney failure.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better, because incomplete treatment can allow the infection to return and can promote antibiotic resistance. Swallow the capsule whole with a glass of water; do not crush or chew it. You may take it with or without food, but taking it with a meal reduces the chance of stomach upset. Drink plenty of water throughout the day to help loosen mucus. Avoid alcohol while taking this medicine, as it can worsen stomach irritation and dizziness. Inform your doctor if you have kidney or liver problems, asthma, or a history of allergies, especially to penicillin. Do not use this medicine for a viral infection like a cold or flu. Keep it out of reach of children. If you are pregnant, planning pregnancy, or breastfeeding, tell your doctor before taking this medicine. Do not share this medicine with anyone else, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function, which can cause amoxycillin to accumulate and increase the risk of side effects. Kidney function should be checked before prescribing, and the dose may need to be adjusted. Elderly patients may also be more sensitive to dizziness and stomach upset. Monitor for signs of allergic reactions and ensure adequate hydration.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Amoxycillin is generally considered safe in pregnancy, but bromhexine should be used only if clearly needed. If you become pregnant while taking this medicine, inform your doctor immediately. Do not start or stop any medicine without medical advice when trying to conceive.
🏥 Post-Surgery Considerations
If you have recently had surgery, inform your surgeon and anaesthesiologist that you are taking this medicine. Antibiotics can interact with other medicines used during surgery. Your doctor will decide whether to continue or temporarily stop the medicine before surgery. This medicine is not routinely prescribed after surgery unless there is a bacterial infection.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. Antibiotics can affect the balance of bacteria in the mouth and may interact with other medicines used during dental work. Your dentist may advise you to continue or adjust the dose. Do not stop the medicine without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may feel tired or dizzy. Avoid strenuous exercise until you feel better. Light activity like walking is fine if you feel up to it. If you have breathing difficulty, stop exercising and consult your doctor. Do not push yourself too hard; rest is important for recovery from a respiratory infection.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or stomach upset in some people. Avoid driving or operating heavy machinery until you know how it affects you. You can usually continue light office work, but take rest if you feel tired. If your job involves heavy physical labour, you may need to take a few days off until your symptoms improve. Follow your doctor's advice about returning to work.
🛑 When to Stop This Medicine
Stop taking this medicine only after completing the full course prescribed by your doctor. Do not stop early even if you feel better. If you experience a severe allergic reaction, severe diarrhoea, or any serious side effect, stop the medicine immediately and seek medical help. If you need to stop for any other reason, consult your doctor first.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless specifically prescribed for a chronic condition. Prolonged use of amoxycillin can lead to antibiotic resistance, fungal infections, and rarely liver or kidney problems. Bromhexine is generally well tolerated for short-term use. If you need this medicine for more than 2 weeks, your doctor should monitor your liver and kidney function and review the need for continued treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and relieve chest congestion naturally.
Evidence: SupportiveCan help clear nasal passages and reduce congestion.
Evidence: SupportiveTechniques to help clear secretions from the airways.
Evidence: Well-established for certain respiratory conditionsAmbroxol is an active metabolite of Bromhexine and may be used as an alternative mucolytic.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are due for a vaccine, inform your doctor that you are taking an antibiotic. In general, antibiotics do not interfere with vaccine effectiveness. If you have a fever, your doctor may advise postponing vaccination until you recover.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel, as some countries have strict rules about antibiotics. Store it in your hand luggage to avoid extreme temperatures in checked baggage. Keep it away from direct sunlight and moisture. If crossing time zones, continue taking the medicine at the same intervals as prescribed; you may need to adjust the timing gradually. Do not pack it in a way that exposes it to high heat or freezing. Check customs regulations for carrying prescription medicines into your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 24 to 72 hours, but it is important to complete the full course prescribed by your doctor. If symptoms do not improve within 5 to 7 days, consult your doctor.
A: Yes, you can take it with or without food. Taking it with a meal is better because it reduces the chance of stomach upset.
A: If you remember within a few hours, take the missed dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Amoxycillin is generally considered safe in pregnancy when prescribed by a doctor. Bromhexine should be used only if the benefit outweighs the risk. Always consult your doctor before taking any medicine during pregnancy.
A: No, you must complete the full course prescribed by your doctor. Stopping early can allow the infection to return and can lead to antibiotic resistance.
A: This medicine is not known to cause significant drowsiness, but some people may feel dizzy. Avoid driving or operating machinery until you know how it affects you.
🤔 Common Patient Concerns
🔄 Substitutes for Trimox BX 500mg/8mg Tablet
View AllAlternative brands with exact same active ingredient:
-
mycocin forte capsuleAdcock Ingram Healthcare Pvt Ltd ₹37.75 36.6% CHEAPER
-
bromolin 500 mg/8 mg capsuleCipla Ltd ₹51.88 12.8% CHEAPER
-
amexine 500mg/8mg capsulePfizer Ltd ₹55.57 6.6% CHEAPER
-
ambrox forte 500mg/8mg capsuleCyper Drugs & Pharmaceuticals Pvt Ltd ₹65.00 9.2% COSTLIER
-
ambro 500mg/8mg capsuleBIO Ethicals Pharma Limited ₹65.00 9.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine contains an antibiotic that only works against bacteria. The common cold is caused by viruses, so this medicine will not help and may cause unnecessary side effects. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full course prescribed by your doctor. Stopping early can allow the infection to return and can promote antibiotic resistance. - Myth: This medicine is safe to take without a prescription.
Fact: This is a prescription medicine. It should only be taken when prescribed by a qualified doctor after proper evaluation. - Myth: Taking this medicine with alcohol is fine.
Fact: Alcohol can worsen stomach upset, nausea, and dizziness. It is best to avoid alcohol while taking this medicine.
🔄 Alternative Options
Generic Alternatives
- Amoxycillin 500 mg + Bromhexine 8 mg capsule (various manufacturers)
Brand Alternatives
- Admox Plus 500mg/8mg capsule