bdparib 300 tablet - Uses, Price, Side Effects & Substitutes
What is bdparib 300 tablet used for?
Bdparib 300 Tablet (Rucaparib) is used to treat . It contains Rucaparib (300mg), which Inhibits poly (ADP-ribose) polymerase (PARP) enzymes, leading to accumulation of. Always consult your doctor before use. Take as prescribed.
- Generic Name: Rucaparib
- Manufacturer: BDR Pharmaceuticals Internationals Pvt
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ bdparib 300 tablet Uses & Benefits
Maintenance treatment of recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer with BRCA mutation; treatment of advanced BRCA-mutated breast cancer.
Off-label uses: Pancreatic cancer, prostate cancer with BRCA mutations.
๐ Drug Information
| Generic Name(s) | Rucaparib |
| Brand Name | Bdparib 300 Tablet |
| Manufacturer | BDR Pharmaceuticals Internationals Pvt |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | |
| Action Class | Anticancer-others |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits poly (ADP-ribose) polymerase (PARP) enzymes, leading to accumulation of DNA damage and cell death in BRCA-mutated cancer cells.
Mechanism Steps
๐ก How to Take bdparib 300 tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bdparib 300 tablet
โ Common Side Effects
- Nausea
- Fatigue
- Anemia
- Thrombocytopenia
- Increased ALT/AST
๐จ Serious Side Effects
- Myelodysplastic syndrome
- Acute myeloid leukemia
- Severe hepatotoxicity
โ ๏ธ Rare Side Effects
- Interstitial lung disease
- QTc prolongation
- Hypersensitivity reactions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| CYP2D6 substrates | Major | Increased exposure of substrate |
| CYP1A2 substrates | Major | Increased exposure of substrate |
๐จ Major Interactions
- CYP2D6 substrates
- CYP1A2 substrates
โก Moderate Interactions
- CYP3A4 substrates
- P-glycoprotein substrates
โน๏ธ Minor Interactions
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Avoid grapefruit juice (may increase exposure).
๐ท Alcohol Interaction
No specific interaction; avoid excessive alcohol due to hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to rucaparib or any excipients; concurrent use with strong CYP2D6 or CYP1A2 inducers.
๐ Monitoring Parameters
Complete blood count, liver function tests, renal function, serum electrolytes.
๐คฑ Lactation Safety
Not recommended; unknown if excreted in human milk.
๐ Overdose Management
No specific antidote; supportive care and monitoring of hematologic parameters.
โฐ Missed Dose
If missed, take as soon as remembered unless next dose is within 12 hours; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for bdparib 300 tablet
View AllAlternative brands with exact same active ingredient (Rucaparib (300mg)):
Medical Note: Always consult your doctor before switching medications.