amplus kid tablet - Amoxycillin (500mg) + Dicloxacillin (500mg) medicine

Amplus Kid Tablet: Complete Medicine Guide

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🏭 Jagsonpal Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for susceptible bacterial infections.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is amplus kid tablet used for?

This medicine is a combination antibiotic containing amoxycillin and dicloxacillin, used to treat various bacterial infections. It works by killing bacteria and is taken orally with food. Complete the full course as prescribed.

  • Generic Name: Amoxycillin (500mg) + Dicloxacillin (500mg)
  • Manufacturer: Jagsonpal Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 amplus kid tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एक संयुक्त एंटीबायोटिक है जिसमें अमोक्सिसिलिन और डाइक्लोक्सासिलिन होते हैं। यह त्वचा, श्वसन तंत्र, मूत्र मार्ग और दांतों के बैक्टीरियल संक्रमण के इलाज के लिए उपयोग की जाती है। यह बैक्टीरिया को मारकर काम करती है। इसे डॉक्टर के निर्देशानुसार भोजन के साथ लें और पूरा कोर्स पूरा करें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और त्वचा पर दाने शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, गंभीर त्वचा प्रतिक्रियाएं और दस्त शामिल हो सकते हैं। किसी भी असामान्य लक्षण पर डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। भोजन के साथ लें ताकि पेट खराब न हो। एलर्जी, गुर्दे या लीवर की बीमारी हो तो डॉक्टर को बताएं। शराब न पिएं। दाने, सूजन या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 amplus kid tablet Uses & Benefits

[{"condition":"Skin and soft tissue infections","description":"Effective against many bacterial skin infections, including cellulitis, abscesses, and wound infections, especially those caused by staphylococci and streptococci.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"Used for upper and lower respiratory tract infections such as sinusitis, pharyngitis, and pneumonia when caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"May be used for uncomplicated urinary tract infections caused by susceptible organisms.","evidence":"Established"},{"condition":"Dental infections","description":"Prescribed for dental abscesses and other odontogenic infections to cover both aerobic and anaerobic bacteria.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Lyme disease","description":"Amoxycillin is sometimes used off-label for early Lyme disease, but dicloxacillin is not typically included.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Skin infections, Respiratory tract infections, Urinary tract infections, Dental infections

📋 Drug Information

Generic Name(s)Amoxycillin (500mg) + Dicloxacillin (500mg)
Brand Nameamplus kid tablet
ManufacturerJagsonpal Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full course even if you feel better after a few days.
3
Do not share this medicine with others.
4
Inform your doctor if you have kidney or liver disease.
5
Avoid alcohol while taking this medicine.
6
Report any rash, swelling, or difficulty breathing immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Skin infection with pus
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmoxycillin and dicloxacillin are both absorbed from the gastrointestinal tract. Amoxycillin absorption is rapid and relatively complete, while dicloxacillin absorption is also good but may be slightly reduced by food. Peak plasma concentrations are generally reached within 1-2 hours.
DistributionBoth drugs distribute widely into body tissues and fluids, including skin, soft tissues, and respiratory secretions. Amoxycillin penetrates well into most body fluids, while dicloxacillin is highly protein-bound and distributes primarily in extracellular fluid.
Protein BindingAmoxycillin is approximately 17-20% protein-bound. Dicloxacillin is approximately 95-99% protein-bound.
MetabolismAmoxycillin undergoes limited metabolism, primarily excreted unchanged. Dicloxacillin is metabolized in the liver to a limited extent.
Half-LifeAmoxycillin half-life is approximately 1-1.5 hours. Dicloxacillin half-life is approximately 0.5-0.9 hours.
ExcretionBoth drugs are primarily excreted unchanged in the urine. Amoxycillin is excreted via glomerular filtration and tubular secretion. Dicloxacillin is excreted in urine and bile.
BioavailabilityAmoxycillin bioavailability is approximately 80-90%. Dicloxacillin bioavailability is approximately 35-76%.
Onset of ActionAntibacterial effect begins within 1-2 hours after oral administration, but clinical improvement may take 24-48 hours.
Peak Plasma TimeAmoxycillin: 1-2 hours. Dicloxacillin: 1-2 hours.
Duration of ActionThe antibacterial effect lasts approximately 6-8 hours, requiring dosing every 6-8 hours.

How It Works

This medicine works by inhibiting bacterial cell wall synthesis. Amoxycillin and dicloxacillin are beta-lactam antibiotics that bind to penicillin-binding proteins (PBPs) in the bacterial cell wall, preventing cross-linking of peptidoglycan and leading to bacterial cell lysis and death. Dicloxacillin is resistant to penicillinase enzymes produced by some bacteria, making it effective against penicillinase-producing staphylococci.

Mechanism Steps

1
Binding to penicillin-binding proteins: The beta-lactam ring of amoxycillin and dicloxacillin binds covalently to penicillin-binding proteins (PBPs) on the bacterial cell membrane.
2
Inhibition of cell wall synthesis: This binding inhibits the transpeptidation reaction required for cross-linking peptidoglycan chains, weakening the bacterial cell wall.
3
Bacterial cell lysis: The weakened cell wall leads to osmotic instability and ultimately bacterial cell lysis and death.

💡 How to Take amplus kid tablet

Strength: Tablet containing Amoxycillin 500 mg and Dicloxacillin 500 mg.

1Take the tablet orally with a full glass of water.
2Take with food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed.
5Complete the full course of treatment.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally every 6 to 8 hours, depending on the severity of the infection. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Consult a doctor for individualized dosing.
Renal ImpairmentDose adjustment is required in patients with renal impairment. Consult a doctor for specific dosing recommendations based on creatinine clearance.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor.
Maximum Daily DoseThe maximum daily dose should not exceed 4 grams of the combination, but must be individualized by a clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves absorption.
Alcohol
Avoid
May increase stomach upset and reduce efficacy.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of amplus kid tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If persistent, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If severe or bloody, contact your doctor immediately.
Skin rash (Common (3-5%))
Stop the medicine and consult your doctor if rash appears.
Vomiting (Common (3-5%))
Take with food and plenty of water. Consult doctor if persistent.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of face, lips, throat, difficulty breathing, or severe dizziness.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Contact your doctor if you develop severe, persistent diarrhea, abdominal pain, or fever.
Stevens-Johnson syndrome (Very rare (<0.01%))
Seek immediate medical attention if you develop a painful rash, blistering, or peeling skin.

⚠️ Rare Side Effects

Seizures
Seek emergency medical help if seizures occur, especially in patients with kidney disease.
Blood dyscrasias
Report unusual bruising or bleeding to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Methotrexate Major
Allopurinol Moderate
Oral contraceptives Moderate
Probenecid Minor

🚨 Major Interactions

  • Warfarin
  • Methotrexate

⚡ Moderate Interactions

  • Allopurinol
  • Oral contraceptives

🍷 Alcohol Interaction

Alcohol may increase the risk of stomach upset and should be avoided while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to penicillins or cephalosporins","Previous severe allergic reaction to beta-lactam antibiotics","Infectious mononucleosis (increased risk of rash)"]

⚠️ Warnings & Precautions

["Use with caution in patients with kidney disease; dose adjustment may be required.","Use with caution in patients with liver disease.","May cause false-positive results in urine glucose tests.","Prolonged use may lead to superinfection with resistant organisms.","Ensure adequate hydration during treatment."]

🤱 Lactation Safety

Amoxycillin and dicloxacillin are excreted in breast milk. Use with caution; consult your doctor to weigh benefits and risks.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhea, and electrolyte imbalance. Management is symptomatic and supportive. In severe cases, hemodialysis may be considered. Contact a poison control center or emergency department immediately.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Take with food to reduce stomach upset. Inform your doctor if you have kidney disease, liver disease, or a history of allergies. Avoid alcohol while taking this medicine. If you experience rash, swelling, or difficulty breathing, seek emergency medical help. Do not share this medicine with others. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced renal function; dose adjustment may be needed. Monitor for side effects.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy if you are taking this medicine.

🏥 Post-Surgery Considerations

May be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions.

🦷 Dental Procedures

Often prescribed for dental infections. Inform your dentist if you are taking this medicine.

💚 Lifestyle Tips for Better Results

🏃
Maintain good hygiene to prevent infections.
🥗
Stay hydrated.
😴
Eat a balanced diet to support immunity.
💧
Get adequate rest.
🧘
Avoid sharing personal items.

🏋️ Exercise Considerations

No specific exercise restrictions, but rest if you feel unwell.

🥗 Diet Recommendations

Take with food to reduce stomach upset.
Stay well hydrated.
Avoid alcohol.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tiredness in some people. Avoid driving or operating machinery if you feel unwell.

🛑 When to Stop This Medicine

Stop only if your doctor advises or if you experience a severe allergic reaction. Do not stop prematurely.

📅 Long-Term Use Effects

Long-term use may lead to antibiotic resistance and superinfections. Regular monitoring of renal and hepatic function is advised for prolonged therapy. Use only as prescribed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Other antibiotics

Depending on the infection, other antibiotics may be prescribed.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions known. Continue routine vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing intervals as advised by your doctor. Declare it at customs if required.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with a skin infection
He was prescribed this medicine for a recurrent skin abscess. He took it with food as directed and completed the 7-day course. The infection cleared without complications.
💡 Lesson: Taking the full course and following food instructions helps ensure cure and prevents recurrence.
👤 A 50-year-old woman with a dental abscess
She experienced severe tooth pain and swelling. Her dentist prescribed this medicine. After 3 days, the pain reduced significantly, and she completed the course. She reported mild nausea, which was managed by taking the tablet with meals.
💡 Lesson: Taking with food minimizes gastrointestinal side effects and improves adherence.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24-48 hours, but complete the full course as prescribed.

Q: Can I take it with food?

A: Yes, take it with food to reduce stomach upset.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: Antibiotics can cure viral infections like the flu.
    Fact: This medicine is only effective against bacterial infections, not viruses.
  • Myth: You can stop taking antibiotics once you feel better.
    Fact: You must complete the full course to prevent recurrence and resistance.

🔄 Alternative Options

Generic Alternatives

  • Amoxycillin and Dicloxacillin combination (generic)

📊 Comparison with Similar Medicines

[{"medicine":"Amoxycillin and Dicloxacillin","composition":"Amoxycillin 500 mg + Dicloxacillin 500 mg","uses":"Skin, respiratory, urinary, dental infections","notes":"Combination provides broad-spectrum and penicillinase-resistant coverage."},{"medicine":"Amoxycillin and Clavulanic acid","composition":"Amoxycillin 500 mg + Clavulanic acid 125 mg","uses":"Broad-spectrum including beta-lactamase producing bacteria","notes":"Clavulanic acid inhibits beta-lactamase enzymes."}]

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