adesure 400mg tablet
What is adesure 400mg tablet used for?
Adesure 400mg Tablet (S-Adenosyl L-Methionine Disulfate Tosylate) is used to treat . It contains S-Adenosyl L-Methoinine Disulfate Tosylate (400mg), which Donates methyl groups for synthesis of neurotransmitters, phospholipids, and nuc. Always consult your doctor before use. Take as prescribed.
- Generic Name: S-Adenosyl L-Methionine Disulfate Tosylate
- Manufacturer: Solarium Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ adesure 400mg tablet Uses & Benefits
Major depressive disorder, osteoarthritis, liver disease (cholestasis, cirrhosis), fibromyalgia
Off-label uses: Chronic fatigue syndrome, migraine prophylaxis, Alzheimer's disease
๐ Drug Information
| Generic Name(s) | S-Adenosyl L-Methionine Disulfate Tosylate |
| Brand Name | Adesure 400mg Tablet |
| Manufacturer | Solarium Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | |
| Action Class | Methyl donor, antioxidant, antidepressant |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from moisture and light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Donates methyl groups for synthesis of neurotransmitters, phospholipids, and nucleic acids; increases glutathione levels
Mechanism Steps
๐ก How to Take adesure 400mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of adesure 400mg tablet
โ Common Side Effects
- Nausea
- Diarrhea
- Headache
- Insomnia
- Dizziness
๐จ Serious Side Effects
- Serotonin syndrome
- Mania/hypomania in bipolar patients
- Seizures
โ ๏ธ Rare Side Effects
- Allergic reactions
- Hepatotoxicity (paradoxical)
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Increased risk of serotonin syndrome |
| SSRIs | Major | Increased risk of serotonin syndrome |
| Warfarin | Moderate | Increased INR and bleeding risk |
| Levodopa | Moderate | Reduced efficacy of levodopa |
๐จ Major Interactions
- MAOIs
- Tricyclic antidepressants
- SSRIs
- SNRIs
- Lithium
โก Moderate Interactions
- Levodopa
- Anticoagulants (Warfarin)
- Antiplatelet agents
โน๏ธ Minor Interactions
- Antacids
- H2 blockers
- Proton pump inhibitors
๐ฝ๏ธ Food Interactions
None significant
๐ท Alcohol Interaction
May reduce efficacy; avoid excessive alcohol
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to SAMe; bipolar disorder (may induce mania); pregnancy (category C)
๐ Monitoring Parameters
Liver function tests, renal function, mood changes, signs of serotonin syndrome
๐คฑ Lactation Safety
Not recommended; safety not established
๐ Overdose Management
Supportive care; no specific antidote; monitor for serotonin syndrome
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for adesure 400mg tablet
View AllAlternative brands with exact same active ingredient (S-Adenosyl L-Methoinine Disulfate Tosylate (400mg)):
-
livsam 400mg tabletSkyglow Pharmaceuticals Private Limited โน459.38 12.5% CHEAPER
-
adniva 400 tabletPalvin Pharmaceuticals โน550.00 4.8% COSTLIER
-
lesamy 400mg tabletLeeford Healthcare Ltd โน620.00 18.1% COSTLIER
-
ederoz 400mg tabletHauz Pharma Pvt Ltd โน655.31 24.8% COSTLIER
-
samorac 400 tabletVitalae Healthcare โน842.80 60.5% COSTLIER
-
samivio tabletWellvio Healthcare Pvt Ltd โน860.60 63.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Helpful and effective medicine as per my experience. Always consult a doctor.
Helpful and effective medicine as per my experience. Always consult a doctor.
Helpful and effective medicine as per my experience. Always consult a doctor.
This medicine was effective for me. I followed the doctor's advice.
Good quality medicine. Satisfied with the outcome.