Lesuride OD 75 Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- High fever with muscle rigidity, confusion, or sweating
- Involuntary repetitive movements of the face, tongue, or limbs
- Palpitations, fainting, or irregular heartbeat
- Severe abdominal pain or persistent vomiting
- Yellowing of skin or eyes, dark urine, or severe fatigue
- Signs of an allergic reaction such as rash, swelling of face or throat, or difficulty breathing
- Seizures or loss of consciousness
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is Tocid 75mg Tablet used for?
This medicine is a sustained-release tablet containing Levosulpiride 75 mg. It is used to treat nausea, vomiting, and functional dyspepsia by blocking dopamine receptors in the brain and gut. It is usually taken once daily with food. Common side effects include drowsiness and dry mouth. It should not be used in pregnancy, epilepsy, or severe kidney disease.
- Generic Name: Levosulpiride (75mg)
- Manufacturer: Lemford Biotech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Tocid 75mg Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा लेवोसल्पिराइड 75 मिलीग्राम का धीमी गति से रिलीज़ होने वाला टैबलेट है। इसका उपयोग मुख्य रूप से मतली, उल्टी और अपच (फंक्शनल डिस्पेप्सिया) के इलाज के लिए किया जाता है। यह पेट की गति को बढ़ाकर और मस्तिष्क में डोपामाइन रिसेप्टर्स को ब्लॉक करके काम करती है। यह दवा अवसाद और चिंता में भी कभी-कभी सहायक के रूप में दी जाती है। इसे आमतौर पर दिन में एक बार भोजन के साथ लिया जाता है। गर्भवती महिलाओं, मिर्गी रोगियों और गुर्दे की गंभीर बीमारी वाले रोगियों को यह दवा नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुँह सूखना, थकान और हल्की पेट की गड़बड़ी शामिल हैं। कुछ लोगों में भूख बढ़ सकती है या वजन बढ़ सकता है। गंभीर लेकिन दुर्लभ दुष्प्रभावों में न्यूरोलेप्टिक मैलिग्नेंट सिंड्रोम (तेज़ बुखार, मांसपेशियों में अकड़न, भ्रम), टार्डिव डिस्किनेसिया (अनैच्छिक हरकतें), और हृदय की अनियमित धड़कन शामिल हैं। अगर आपको ऐसे लक्षण दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। गाड़ी चलाने या मशीन चलाने से बचें क्योंकि इससे नींद आ सकती है। शराब न पिएं। दवा को भोजन के साथ लें। टैबलेट को चबाएं या तोड़ें नहीं। डॉक्टर की सलाह के बिना दवा बंद न करें। नियमित जांच के लिए डॉक्टर के पास जाएं।
💊 Tocid 75mg Tablet Uses & Benefits
[{"condition":"Functional dyspepsia","description":"Helps relieve symptoms such as bloating, early satiety, and upper abdominal discomfort by improving gastric emptying and reducing nausea.","evidence":"Well-established"},{"condition":"Nausea and vomiting","description":"Used to control nausea and vomiting of various causes, including that induced by chemotherapy or other medications, by blocking dopamine receptors in the brain.","evidence":"Well-established"},{"condition":"Diabetic gastroparesis","description":"May improve gastric emptying and reduce symptoms in patients with delayed stomach emptying due to diabetes.","evidence":"Moderate"},{"condition":"Depression (adjunct)","description":"Sometimes used as an add-on treatment for major depressive disorder when standard antidepressants are not fully effective.","evidence":"Limited"},{"condition":"Anxiety disorders","description":"May be prescribed off-label for anxiety, though evidence is not robust.","evidence":"Limited"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Occasionally used to prevent migraines, but not a first-line treatment.","evidence":"Limited"},{"condition":"Tourette syndrome","description":"May help reduce tics, but other medications are preferred.","evidence":"Limited"},{"condition":"Premature ejaculation","description":"Sometimes prescribed off-label due to its dopamine-blocking effects, but not standard.","evidence":"Limited"}]
Primary treatment for: Functional dyspepsia
Also treats: Nausea and vomiting, Diabetic gastroparesis, Depression (adjunct), Anxiety disorders
📋 Drug Information
| Generic Name(s) | Levosulpiride (75mg) |
| Brand Name | Tocid 75mg Tablet |
| Manufacturer | Lemford Biotech Pvt Ltd |
| Packaging / Form | strip of 10 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively blocking dopamine D2 receptors in the brain and gastrointestinal tract. In the brain, this action helps control nausea and vomiting by inhibiting the chemoreceptor trigger zone. In the gastrointestinal tract, it enhances gastric motility and accelerates gastric emptying by modulating dopamine receptors in the gut wall. Additionally, it may have some effect on serotonin receptors, contributing to its prokinetic and antiemetic properties. The sustained-release formulation provides a gradual release of the active ingredient, allowing for more stable blood levels and potentially fewer side effects compared to immediate-release forms.
Mechanism Steps
💡 How to Take Tocid 75mg Tablet
Strength: Sustained-release tablet, 75 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 75 mg once daily, taken orally. However, the dose may be adjusted by your doctor based on the condition being treated, your age, kidney and liver function, and response to therapy. For nausea and vomiting, it may be taken as needed, while for chronic conditions like functional dyspepsia, it is taken regularly. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially extrapyramidal symptoms and sedation. Start with a lower dose and titrate slowly. Close monitoring is recommended. |
| Renal Impairment | In patients with renal impairment, dose reduction may be necessary. For creatinine clearance between 20-50 mL/min, consider reducing the dose. For creatinine clearance less than 20 mL/min, use is contraindicated. Consult your doctor for individualized dosing. |
| Hepatic Impairment | No specific dosage adjustment is established for hepatic impairment. Use with caution and monitor liver function. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 75 mg, but this may vary based on clinical judgment. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Tocid 75mg Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Metoclopramide | Major | |
| Amiodarone | Major | |
| Levodopa | Major | |
| Diazepam | Moderate | |
| Lisinopril | Moderate | |
| Amitriptyline | Moderate | |
| Aluminum hydroxide | Minor | |
| Cimetidine | Minor | |
| Paracetamol | Minor | |
| Omeprazole | Minor |
🚨 Major Interactions
- Other dopamine antagonists (e.g., metoclopramide, haloperidol)
- QT-prolonging drugs (e.g., amiodarone, sotalol, azithromycin)
- Levodopa
⚡ Moderate Interactions
- CNS depressants (e.g., benzodiazepines, opioids, alcohol)
- Antihypertensives
- Anticholinergics
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol can increase the sedative effects of levosulpiride, leading to excessive drowsiness, dizziness, and impaired judgment. It may also increase the risk of other side effects such as low blood pressure and difficulty concentrating.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to levosulpiride or any component of the formulation","Pheochromocytoma","Epilepsy or history of seizures","Severe renal impairment (creatinine clearance < 20 mL/min)","Concomitant use with levodopa","QT prolongation or congenital long QT syndrome","Pregnancy and lactation (unless clearly needed)"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine.","Use with caution in elderly patients due to increased risk of extrapyramidal symptoms.","May increase prolactin levels; monitor for signs of hyperprolactinemia.","Do not stop abruptly; taper gradually under medical supervision.","Use with caution in patients with cardiovascular disease.","May impair ability to regulate body temperature; avoid overheating.","Inform your doctor if you have a history of seizures, liver disease, or kidney disease."]
🤱 Lactation Safety
Levosulpiride is excreted in breast milk. It is not recommended during breastfeeding unless clearly needed. Consult your doctor to weigh the benefits and risks.
💊 Overdose Management
Overdose may cause severe drowsiness, extrapyramidal symptoms, hypotension, and cardiac arrhythmias. There is no specific antidote. Treatment is supportive and symptomatic. If overdose is suspected, seek immediate medical attention. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and ECG continuously.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Before taking this medicine, tell your doctor if you have a history of heart problems, seizures, liver or kidney disease, or if you are pregnant or planning to become pregnant. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness. Do not drink alcohol while taking this medicine, as it can increase sedation and impair your ability to think clearly. Take this medicine at the same time each day, preferably with food to reduce stomach upset. Do not crush, chew, or break the sustained-release tablet; swallow it whole. If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose. Keep all appointments with your doctor for regular monitoring of your symptoms, heart rhythm, and blood tests. Do not stop this medicine abruptly without consulting your doctor, as withdrawal symptoms may occur.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more susceptible to extrapyramidal symptoms, sedation, and orthostatic hypotension. Start with a lower dose and monitor closely. Regular assessment of renal function is important, as dose adjustment may be needed.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is not recommended during pregnancy unless clearly needed. Your doctor may consider alternative treatments.
🏥 Post-Surgery Considerations
After surgery, this medicine may be used to treat postoperative nausea and vomiting. However, it should be used with caution due to potential effects on blood pressure and heart rhythm. Inform your surgeon and anesthesiologist about all medications you are taking.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with anesthetics or other medications used during dental procedures. It may also cause dry mouth, which can affect oral health. Maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. Light to moderate exercise is generally safe, but listen to your body and stop if you feel unwell.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and dizziness, which may affect your ability to drive, operate machinery, or perform tasks requiring mental alertness. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job involves operating heavy machinery. The sedative effect may also impact your productivity, so plan your tasks accordingly.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor will determine when and how to stop based on your condition and response to treatment. Abrupt discontinuation may lead to withdrawal symptoms such as nausea, vomiting, insomnia, and agitation. If you experience severe side effects, contact your doctor immediately for guidance.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of tardive dyskinesia, a potentially irreversible movement disorder. Regular monitoring for extrapyramidal symptoms is advised. It may also cause hyperprolactinemia, leading to breast enlargement, galactorrhea, or menstrual irregularities. Periodic assessment of renal and liver function is recommended. Do not use for longer than necessary without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Eating small, frequent, low-fat meals can help manage dyspepsia and gastroparesis.
Evidence: Well-establishedYoga, meditation, and deep breathing can reduce stress-related digestive symptoms.
Evidence: ModerateMay help relieve nausea and improve gastric motility in some patients.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medications you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, adjust your dosing schedule gradually under medical advice. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The antiemetic effect may begin within 30 to 60 minutes, while improvement in dyspepsia and mood may take several days to weeks.
A: Some medications may interact with this medicine. Always inform your doctor about all medicines you are taking, including over-the-counter drugs and supplements.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine is not recommended during pregnancy unless clearly needed. Consult your doctor to weigh the benefits and risks.
A: No, do not stop this medicine abruptly without consulting your doctor, as withdrawal symptoms may occur. Your doctor may taper the dose gradually.
🤔 Common Patient Concerns
🔄 Substitutes for Tocid 75mg Tablet
View AllAlternative brands with exact same active ingredient:
-
tilpride 75 mg tablet srTablets India Limited ₹95.72 20.2% CHEAPER
-
retune-ls 75 mg tablet srZuventus Healthcare Ltd ₹105.00 12.5% CHEAPER
-
evopride 75mg tablet srGlobus Labs ₹112.50 6.3% CHEAPER
-
fundys 75mg tablet srGifert Biosciences Pvt Ltd ₹122.81 2.3% COSTLIER
-
Sulgiride 75mg TabletEast West Pharma ₹122.81 2.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a sleeping pill.
Fact: This medicine is not a sleeping pill. It is a prokinetic and antiemetic agent that may cause drowsiness as a side effect. - Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision. - Myth: This medicine is safe to take during pregnancy.
Fact: This medicine is not recommended during pregnancy unless clearly needed. Consult your doctor. - Myth: You can stop this medicine anytime you feel better.
Fact: Do not stop this medicine abruptly without consulting your doctor, as withdrawal symptoms may occur.
🔄 Alternative Options
Generic Alternatives
- Levosulpiride 75 mg sustained-release tablet
Brand Alternatives
- Lesuride OD 75 Tablet