asthamax ax 400mg/30mg tablet - Doxofylline (400mg) + Ambroxol (30mg) medicine

Asthamax AX 400mg/30mg Tablet: Complete Medicine Guide

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🏭 Lemford Biotech Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 18, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for COPD and chronic bronchitis; limited for asthma.
Reviewed by
SaathiMed Expert Panel | Oct 18, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Irregular or very fast heartbeat
  • Seizures

If experiencing severe symptoms, call emergency services immediately.

What is asthamax ax 400mg/30mg tablet used for?

This medicine is a combination of Doxofylline (a bronchodilator) and Ambroxol (a mucolytic) used to treat breathing difficulties in conditions like COPD and chronic bronchitis. It helps relax airways and thin mucus, making it easier to breathe and cough. It is not for sudden asthma attacks.

  • Generic Name: Doxofylline + Ambroxol
  • Manufacturer: Lemford Biotech Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 asthamax ax 400mg/30mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा डॉक्सोफाइलिन और एम्ब्रोक्सोल का संयोजन है, जिसका उपयोग सीओपीडी (क्रॉनिक ऑब्सट्रक्टिव पल्मोनरी डिजीज), क्रॉनिक ब्रोंकाइटिस और अस्थमा जैसी सांस की बीमारियों में किया जाता है। यह वायुमार्ग की मांसपेशियों को आराम देकर सांस लेना आसान बनाती है और बलगम को पतला करके खांसी के साथ बाहर निकालने में मदद करती है। यह दवा अचानक होने वाले गंभीर अस्थमा अटैक के लिए नहीं है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, पेट में असहजता, सिरदर्द और चक्कर आना शामिल हैं। कुछ लोगों को दिल की धड़कन तेज होना या हाथ-पैर कांपना भी महसूस हो सकता है। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर सांस लेने में तकलीफ, चेहरे या गले में सूजन, या दिल की अनियमित धड़कन हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। गोली को चबाएं नहीं, पूरा निगलें। इसे भोजन के साथ या बिना भोजन के ले सकते हैं, लेकिन भोजन के साथ लेने से पेट की जलन कम होती है। इस दवा के साथ शराब न लें। अगर आपको चक्कर या कंपन महसूस हो, तो वाहन न चलाएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। दवा को बंद करने से पहले डॉक्टर से पूछें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 asthamax ax 400mg/30mg tablet Uses & Benefits

[{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Helps relieve bronchospasm and reduce mucus viscosity, improving breathing and cough clearance.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Used to manage chronic bronchitis by relaxing airways and thinning mucus, making it easier to expectorate.","evidence":"Well-established"},{"condition":"Bronchial asthma","description":"May be used as add-on therapy for asthma to improve bronchodilation and mucus clearance, but not for acute attacks.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Acute respiratory distress syndrome (ARDS)","description":"Sometimes used off-label for its mucolytic and anti-inflammatory effects, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Chronic obstructive pulmonary disease (COPD)

Also treats: Chronic bronchitis, Bronchial asthma

📋 Drug Information

Generic Name(s)Doxofylline + Ambroxol
Brand NameAsthamax AX 400mg/30mg Tablet
ManufacturerLemford Biotech Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassRespiratory
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C. Keep away from moisture, heat, and direct sunlight. Keep in the original container, tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day to help thin mucus.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual heart racing, palpitations, or tremors immediately.
7
Do not use this medicine for acute asthma attacks; seek emergency care.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic cough with mucus
This medicine is commonly prescribed for this.
Likely Use
✅
Wheezing
Helps relax airways.
Likely Use
✅
Shortness of breath
Used in COPD and bronchitis.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Dry cough
Not typically used for dry cough.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDoxofylline is rapidly absorbed from the gastrointestinal tract after oral administration. Ambroxol is also well absorbed orally. Food may slightly delay the absorption of Doxofylline but does not significantly affect the extent of absorption.
DistributionBoth drugs are widely distributed in body tissues. Doxofylline has a volume of distribution of approximately 1 L/kg. Ambroxol distributes well into lung tissue and bronchial secretions, which is important for its mucolytic action.
Protein BindingDoxofylline is about 30% bound to plasma proteins. Ambroxol is approximately 90% bound to plasma proteins.
MetabolismDoxofylline is metabolized in the liver by cytochrome P450 enzymes, primarily CYP1A2 and CYP3A4. Ambroxol is metabolized in the liver by conjugation and oxidation.
Half-LifeThe elimination half-life of Doxofylline is approximately 6-8 hours. Ambroxol has a half-life of about 7-12 hours.
ExcretionBoth drugs and their metabolites are primarily excreted via the kidneys in urine. About 90% of a Doxofylline dose is excreted in urine within 24 hours. Ambroxol is excreted mainly as metabolites in urine.
BioavailabilityThe oral bioavailability of Doxofylline is about 60-70%. Ambroxol has an oral bioavailability of approximately 70-80%.
Onset of ActionBronchodilation from Doxofylline begins within 30 minutes to 1 hour after oral intake. Mucolytic effects of Ambroxol may take a few hours to become noticeable.
Peak Plasma TimePeak plasma concentrations of Doxofylline are reached about 1-2 hours after oral administration. Ambroxol peaks at around 1-3 hours.
Duration of ActionThe bronchodilator effect of Doxofylline lasts about 6-8 hours. Ambroxol's mucolytic effect lasts for several hours, requiring multiple daily doses for continuous benefit.

How It Works

This medicine combines two active ingredients with complementary actions. Doxofylline is a xanthine derivative that inhibits phosphodiesterase enzymes, leading to increased cyclic AMP levels in bronchial smooth muscle cells. This causes relaxation of the airways and improved airflow. It also has mild anti-inflammatory effects and may enhance diaphragm contractility. Ambroxol is a mucolytic that reduces mucus viscosity by breaking down acidic mucopolysaccharide fibers and stimulating surfactant production, which helps thin secretions and aids their removal by coughing. Together, they provide bronchodilation and mucus clearance.

Mechanism Steps

1
Phosphodiesterase inhibition by Doxofylline: Doxofylline inhibits phosphodiesterase enzymes in bronchial smooth muscle, increasing cyclic AMP levels.
2
Bronchial smooth muscle relaxation: Elevated cyclic AMP causes relaxation of the smooth muscles lining the airways, leading to bronchodilation.
3
Mucolytic action of Ambroxol: Ambroxol breaks down acidic mucopolysaccharides in mucus, reducing its viscosity and making it easier to cough out.
4
Surfactant stimulation: Ambroxol stimulates the production of surfactant in the lungs, which helps keep airways open and aids mucus clearance.
5
Combined effect: The combination results in widened airways and thinner mucus, improving overall respiratory function and symptom relief.

💡 How to Take asthamax ax 400mg/30mg tablet

Strength: Each tablet contains Doxofylline 400 mg and Ambroxol 30 mg.

1Wash your hands before handling the tablet.
2Take the tablet with a full glass of water.
3Swallow the tablet whole; do not crush, chew, or break it.
4You may take it with or without food, but taking it with food may reduce stomach upset.
5Follow the prescribed schedule consistently.
6Do not take more than the recommended dose.
7If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally two to three times daily, or as directed by your physician. The exact dose and frequency depend on the condition being treated, its severity, and your response to therapy. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. Take the tablet whole with water, with or without food.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially cardiac effects. Dose may need to be reduced based on kidney and liver function. Close monitoring is advised.
Renal ImpairmentIn patients with renal impairment, dose reduction may be necessary. Consult your doctor for individualized dosing.
Hepatic ImpairmentIn patients with hepatic impairment, dose reduction may be necessary. Consult your doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is 3 tablets (1200 mg Doxofylline and 90 mg Ambroxol) per day, but this must be confirmed by your doctor. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine
Limit
May increase stimulant effects like palpitations.
Alcohol
Avoid
Increases dizziness and heart rate.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of asthamax ax 400mg/30mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated. If vomiting is severe or persistent, contact your doctor.
Stomach discomfort (Common (5-10%))
Take with meals. Avoid spicy foods. Consult doctor if it worsens.
Headache (Common (5-10%))
Rest and stay hydrated. Use a mild pain reliever if needed, but consult your doctor first.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you feel normal. Lie down if needed.
Increased heart rate (Uncommon (1-5%))
Monitor your pulse. If it feels very fast or irregular, seek medical advice.
Palpitations (Uncommon (1-5%))
Report to your doctor if you feel your heart racing or fluttering.
Tremors (Uncommon (1-5%))
Usually temporary. If bothersome, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience rash, swelling of face or throat, or difficulty breathing.
Irregular heartbeat (arrhythmia) (Rare (<0.1%))
Contact your doctor right away if you feel palpitations, chest pain, or fainting.
Severe skin reactions (Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop the medicine and seek immediate medical attention if you develop a painful rash, blisters, or peeling skin.
Liver damage (hepatotoxicity) (Rare (<0.1%))
Report yellowing of eyes or skin, dark urine, or severe abdominal pain to your doctor immediately.

⚠️ Rare Side Effects

Seizures
Seek emergency medical care if seizures occur.
Blood disorders (e.g., thrombocytopenia)
Report unusual bleeding or bruising to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ciprofloxacin Major
Erythromycin Major
Propranolol Major
Phenytoin Moderate
Rifampicin Moderate
Cimetidine Moderate
Furosemide Moderate
Antacids Minor
Caffeine Minor
Alcohol Moderate

🚨 Major Interactions

  • Ciprofloxacin
  • Erythromycin
  • Propranolol
  • Phenytoin

⚡ Moderate Interactions

  • Rifampicin
  • Cimetidine
  • Diuretics (e.g., furosemide)

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine. Both Doxofylline and alcohol can increase heart rate and cause dizziness or drowsiness. Combining them may worsen these effects and increase the risk of falls or accidents. It may also put extra strain on the liver.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Doxofylline, Ambroxol, or any component of the formulation","Acute myocardial infarction","Severe cardiac arrhythmias","Severe liver disease","Severe renal impairment","Children under 12 years (safety not established)","Breastfeeding (unless advised by doctor)"]

⚠️ Warnings & Precautions

["Use with caution in patients with heart disease, hypertension, or arrhythmias.","May impair ability to drive or operate machinery; avoid until you know how it affects you.","Avoid alcohol consumption.","Do not exceed the prescribed dose.","Consult doctor before use in pregnancy or breastfeeding.","May interact with other medications; inform your doctor about all medicines you take.","Not for acute asthma attacks; seek emergency care for sudden severe breathing difficulty."]

🤱 Lactation Safety

Not established from the available information. Doxofylline and Ambroxol may pass into breast milk. Consult your doctor before breastfeeding while on this medicine.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, rapid heart rate, seizures, or irregular heartbeat. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and cardiac rhythm.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with a glass of water. It can be taken with or without food, but taking it with food may reduce stomach upset. Avoid alcohol while taking this medicine, as it can increase drowsiness and heart rate. Do not drive or operate heavy machinery if you feel dizzy or shaky. Inform your doctor if you have heart disease, high blood pressure, liver or kidney problems, or if you are pregnant or breastfeeding. Do not stop taking this medicine suddenly without consulting your doctor. Keep it out of reach of children. Store at room temperature, away from moisture and direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the cardiac and central nervous system effects of this medicine. Dose reduction may be needed based on kidney and liver function. Close monitoring for side effects is recommended.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established. Your doctor may consider alternative treatments.

🏥 Post-Surgery Considerations

If you have recently had surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect heart rate. Your doctor may advise temporary discontinuation.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may cause dry mouth or interact with local anesthetics. No major precautions are typically needed, but your dentist may adjust treatment.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on your lungs.
🥗
Regular low-impact exercise like walking or swimming can improve breathing.
😴
Practice good posture to allow better lung expansion.
💧
Include anti-inflammatory foods like fruits and vegetables in your diet.
🧘
Get adequate sleep to support overall health.
🌞
Avoid smoking and exposure to secondhand smoke.

🏋️ Exercise Considerations

While taking this medicine, you may feel dizzy or have a rapid heartbeat. Avoid strenuous exercise until you know how the medicine affects you. Light to moderate exercise is generally safe, but consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce processed and fried foods.
Stay well hydrated to help thin mucus.
Limit caffeine intake as it may increase heart rate.
Eat plenty of fruits and vegetables rich in antioxidants.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or palpitations, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is generally safe to continue desk work, but take breaks if you feel dizzy.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, your doctor may advise stopping or changing the medicine. If your symptoms improve and you feel you no longer need it, consult your doctor before stopping.

📅 Long-Term Use Effects

Long-term use of this medicine may require periodic monitoring of heart rate, liver function, and kidney function. Some patients may develop tolerance to the bronchodilator effect. It is important to have regular follow-ups with your doctor to assess the continued need and adjust the dose if necessary. Rarely, long-term use may be associated with cardiac arrhythmias or liver enzyme elevations.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Pulmonary rehabilitation

A program of exercise, education, and support to improve breathing and quality of life.

Evidence: Well-established
Steam inhalation

Can help loosen mucus and ease breathing temporarily.

Evidence: Limited
Chest physiotherapy

Techniques to help clear mucus from the airways.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Patients with chronic respiratory diseases are advised to receive influenza and pneumococcal vaccines as per guidelines. This medicine does not interact with vaccines, but consult your doctor for timing.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust dosing times gradually as advised by your doctor. Keep enough supply for your trip. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with chronic bronchitis
He was prescribed this medicine for his persistent cough and breathlessness. After taking it regularly for two weeks, he noticed that his cough became more productive and breathing felt easier. He took it with breakfast and dinner as advised, which helped avoid stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 62-year-old woman with COPD
She started this medicine along with her inhaler. She initially felt dizzy, so her doctor advised her to take it at night. She also avoided alcohol and caffeine, which reduced her palpitations. Over time, her breathing improved, and she could walk longer distances.
💡 Lesson: Adjusting timing and avoiding stimulants can minimize side effects while maintaining benefits.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Bronchodilation begins within 30 minutes to 1 hour, but full benefits for mucus clearance may take a few days of regular use.

Q: Can I take it with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue your regular schedule. Do not double dose.

Q: Is it safe during pregnancy?

A: Consult your doctor. The safety of this medicine during pregnancy is not well established.

Q: Can I stop taking it suddenly?

A: Do not stop without consulting your doctor. Sudden discontinuation may worsen symptoms.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for asthamax ax 400mg/30mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure asthma permanently.
    Fact: This medicine helps manage symptoms but does not cure asthma or COPD. It should be used as part of a comprehensive treatment plan.
  • Myth: It can be taken for any cough.
    Fact: This medicine is specifically for respiratory conditions with bronchospasm and thick mucus. It is not for dry cough or cough due to cold.
  • Myth: More tablets mean faster relief.
    Fact: Taking more than the prescribed dose can cause serious side effects. Always follow your doctor's instructions.

🔄 Alternative Options

Generic Alternatives

  • Doxofylline 400 mg + Ambroxol 30 mg tablet (various manufacturers)

Brand Alternatives

  • Asthamax AX 400mg/30mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Doxofylline 400 mg + Ambroxol 30 mg","uses":"COPD, chronic bronchitis","notes":"Combination provides bronchodilation and mucolysis."},{"medicine":"Doxofylline alone","composition":"Doxofylline 400 mg","uses":"COPD, asthma","notes":"Bronchodilator only; no mucolytic action."},{"medicine":"Ambroxol alone","composition":"Ambroxol 30 mg","uses":"Productive cough, bronchitis","notes":"Mucolytic only; no bronchodilation."}]

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