gonta l 75mg/40mg capsule sr - Levosulpiride (75mg) + Pantoprazole (40mg) medicine

Pantocid L Capsule SR: Complete Guide to Uses, Side Effects, and Safety

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🏭 Vervetic Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Use in pregnancy only if clearly needed and after consulting your doctor. Both Levosulpiride and Pantoprazole should be used with caution during pregnancy. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for GERD and functional dyspepsia; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

When to Call Your Doctor IMMEDIATELY

  • Uncontrolled muscle movements or tremors
  • Severe dizziness or fainting
  • Palpitations or irregular heartbeat
  • Difficulty breathing or swelling of face, lips, or throat
  • Severe abdominal pain or blood in vomit/stool
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is gonta l 75mg/40mg capsule sr used for?

This medicine is a combination of Levosulpiride and Pantoprazole used to treat acid reflux, heartburn, and motility disorders. It works by reducing stomach acid and improving gastric emptying. It is usually taken once daily before breakfast.

  • Generic Name: Levosulpiride (75mg) + Pantoprazole (40mg)
  • Manufacturer: Vervetic Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 gonta l 75mg/40mg capsule sr के बारे में (Hindi Summary)

उपयोग: यह दवा लेवोसल्पिराइड और पैंटोप्राजोल का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, हार्टबर्न, अपच, और गैस्ट्रोपैरेसिस के इलाज के लिए किया जाता है। यह पेट में एसिड को कम करती है और पेट की खाली होने की गति को बढ़ाती है। इसे आमतौर पर सुबह नाश्ते से पहले खाली पेट लिया जाता है।

साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, चक्कर आना, नींद आना, मुँह सूखना, दस्त, कब्ज, पेट दर्द और जी मिचलाना शामिल हैं। गंभीर दुष्प्रभावों में अनैच्छिक मांसपेशीय हरकतें, दिल की धड़कन में गड़बड़ी, और एलर्जी प्रतिक्रियाएँ हो सकती हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। कैप्सूल को चबाएं या तोड़ें नहीं, पूरा निगलें। इसे सुबह नाश्ते से 30-60 मिनट पहले खाली पेट लें। शराब का सेवन न करें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। गाड़ी चलाने या मशीन चलाने से बचें जब तक कि आपको इसका असर पता न चल जाए। यदि आपको हृदय, यकृत, या गुर्दे की बीमारी है तो डॉक्टर को बताएं।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 gonta l 75mg/40mg capsule sr Uses & Benefits

[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Reduces acid reflux and heartburn by suppressing gastric acid secretion and improving gastric emptying.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"Helps relieve symptoms like bloating, early satiety, and upper abdominal discomfort by promoting gastric motility and reducing acid.","evidence":"Moderate"},{"condition":"Diabetic gastroparesis","description":"Improves delayed gastric emptying and associated nausea, vomiting, and bloating in diabetic patients.","evidence":"Moderate"},{"condition":"Nausea and vomiting","description":"Levosulpiride component helps control nausea and vomiting by its prokinetic and antiemetic actions.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Irritable bowel syndrome (IBS)","description":"Sometimes prescribed off-label to relieve bloating and motility issues, but evidence is limited.","evidence":"Limited"},{"condition":"Non-ulcer dyspepsia","description":"May be used off-label for dyspeptic symptoms without ulcer, though not first-line.","evidence":"Limited"}]

Primary treatment for: Gastroesophageal reflux disease (GERD)

Also treats: Functional dyspepsia, Diabetic gastroparesis, Nausea and vomiting

📋 Drug Information

Generic Name(s)Levosulpiride (75mg) + Pantoprazole (40mg)
Brand Namegonta l 75mg/40mg capsule sr
ManufacturerVervetic Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine on an empty stomach, at least 30-60 minutes before breakfast, for best results.
2
Swallow the capsule whole; do not crush or chew it.
3
Avoid alcohol while taking this medicine to prevent increased drowsiness and dizziness.
4
Do not drive or operate heavy machinery until you know how this medicine affects you.
5
Inform your doctor if you have a history of heart rhythm problems, liver disease, or kidney disease.
6
Do not stop this medicine abruptly without consulting your doctor.
7
Report any unusual muscle movements, palpitations, or severe allergic reactions immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Heartburn
This medicine is commonly prescribed for this.
Likely Use
Acid regurgitation
This medicine helps reduce acid reflux.
Likely Use
Bloating
This medicine improves gastric motility and reduces bloating.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLevosulpiride is rapidly absorbed after oral administration. Pantoprazole is also well absorbed, but its absorption may be delayed when taken with food. The sustained-release formulation of this medicine is designed to release the drugs gradually over time.
DistributionLevosulpiride is widely distributed in the body, including the central nervous system. Pantoprazole distributes mainly in the extracellular fluid and is highly protein-bound.
Protein BindingLevosulpiride is approximately 25% bound to plasma proteins. Pantoprazole is about 98% bound to plasma proteins, primarily albumin.
MetabolismLevosulpiride undergoes minimal hepatic metabolism and is largely excreted unchanged in urine. Pantoprazole is extensively metabolized in the liver by the cytochrome P450 enzyme system, primarily CYP2C19 and to a lesser extent CYP3A4.
Half-LifeThe elimination half-life of Levosulpiride is approximately 6-8 hours. Pantoprazole has a plasma elimination half-life of about 1 hour, but its acid-suppressive effect lasts longer due to irreversible binding to the proton pump.
ExcretionLevosulpiride is mainly excreted unchanged in the urine. Pantoprazole metabolites are excreted primarily in the urine and to a lesser extent in feces.
BioavailabilityThe oral bioavailability of Levosulpiride is about 25-35%. Pantoprazole has an oral bioavailability of approximately 77%.
Onset of ActionLevosulpiride's prokinetic effects may begin within 30-60 minutes. Pantoprazole's acid suppression starts within 1 hour, but maximal effect may take a few days.
Peak Plasma TimeLevosulpiride reaches peak plasma concentration in about 2-3 hours. Pantoprazole peaks at about 2-4 hours after oral administration.
Duration of ActionLevosulpiride's effect lasts about 6-8 hours. Pantoprazole's acid suppression lasts for more than 24 hours due to irreversible binding.

How It Works

This medicine combines two active ingredients with complementary actions. Levosulpiride is a substituted benzamide that acts as a selective dopamine D2 receptor antagonist. It blocks dopamine receptors in the chemoreceptor trigger zone and in the gastrointestinal tract, which enhances gastric motility, accelerates gastric emptying, and exerts antiemetic effects. Pantoprazole is a proton pump inhibitor that irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, thereby suppressing both basal and stimulated gastric acid secretion. Together, they provide acid suppression and improved gastric motility.

Mechanism Steps

1
Dopamine D2 receptor blockade by Levosulpiride: Levosulpiride selectively blocks dopamine D2 receptors in the gastrointestinal tract and brain, which enhances gastric motility and reduces nausea.
2
Prokinetic effect: By blocking D2 receptors, Levosulpiride accelerates gastric emptying and improves coordination between the stomach and duodenum.
3
Proton pump inhibition by Pantoprazole: Pantoprazole irreversibly binds to the H+/K+ ATPase enzyme in gastric parietal cells, blocking the final step of acid secretion.
4
Acid suppression: This leads to a marked reduction in gastric acid production, alleviating heartburn and allowing healing of esophageal irritation.
5
Combined symptomatic relief: The dual action addresses both acid reflux and delayed gastric emptying, providing comprehensive relief in conditions like GERD and dyspepsia.

💡 How to Take gonta l 75mg/40mg capsule sr

Strength: Capsule containing Levosulpiride 75 mg and Pantoprazole 40 mg (sustained-release).

1Take the capsule at least 30-60 minutes before breakfast, unless your doctor advises otherwise.
2Swallow the capsule whole with a glass of water. Do not crush, chew, or break it.
3Do not take with food as it may reduce the absorption of Pantoprazole.
4If you miss a dose, follow the missed dose instructions.
5Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose is one capsule of Levosulpiride 75 mg and Pantoprazole 40 mg taken orally once daily on an empty stomach, preferably 30-60 minutes before breakfast. However, the dose and duration must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function, and response to treatment. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and extrapyramidal symptoms. Dose adjustment may be necessary based on renal and hepatic function. Use with caution and monitor closely.
Renal ImpairmentLevosulpiride is excreted renally, so dose reduction may be required in patients with renal impairment. Pantoprazole does not require dose adjustment in mild to moderate renal impairment, but caution is advised in severe renal impairment. Consult your doctor for individualized dosing.
Hepatic ImpairmentPantoprazole is extensively metabolized in the liver; dose reduction may be needed in severe hepatic impairment. Levosulpiride undergoes minimal hepatic metabolism. Consult your doctor for dose adjustment.
Maximum Daily DoseThe maximum recommended daily dose is one capsule (Levosulpiride 75 mg + Pantoprazole 40 mg) per day. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take on an empty stomach
Food may delay the absorption of Pantoprazole and reduce its efficacy.
Alcohol
Avoid
Alcohol may increase drowsiness and dizziness caused by Levosulpiride.
Caffeine
Limit
Caffeine may increase nervousness and insomnia.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of gonta l 75mg/40mg capsule sr

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Drowsiness (Common (5-10%))
Avoid alcohol and activities requiring alertness.
Dry mouth (Common (5-10%))
Stay hydrated, chew sugar-free gum.
Diarrhea (Common (5-10%))
Drink plenty of fluids. Consult doctor if severe or persistent.
Constipation (Common (5-10%))
Increase fiber and fluid intake.
Abdominal pain (Common (5-10%))
Usually temporary. Consult doctor if severe.
Nausea (Common (5-10%))
Take with food if advised by doctor.

🚨 Serious Side Effects

Extrapyramidal symptoms (tremors, rigidity, abnormal movements) (Rare (<0.1%))
Seek immediate medical attention if you experience uncontrolled movements or muscle stiffness.
Neuroleptic malignant syndrome (fever, muscle rigidity, altered mental status) (Very rare (<0.01%))
Stop the medicine and seek emergency care immediately.
Prolonged QT interval and cardiac arrhythmias (Rare (<0.1%))
Report palpitations, fainting, or irregular heartbeat to your doctor immediately.
Severe allergic reactions (rash, swelling, difficulty breathing) (Rare (<0.1%))
Seek emergency medical help if you experience swelling of face, lips, or throat, or difficulty breathing.
Blood disorders (e.g., leukopenia, thrombocytopenia) (Very rare (<0.01%))
Report unusual bruising, bleeding, or signs of infection to your doctor.

⚠️ Rare Side Effects

Galactorrhea (breast milk production)
Consult your doctor if you notice nipple discharge.
Gynecomastia (breast enlargement in men)
Report to your doctor for evaluation.
Liver enzyme elevation
Regular monitoring may be needed. Report jaundice or dark urine.
Photosensitivity
Use sunscreen and avoid excessive sun exposure.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Antipsychotics Major
QT-prolonging drugs Major
Levodopa Major
Methotrexate Major
Ketoconazole Moderate
Atazanavir Moderate
Clopidogrel Moderate
Warfarin Moderate
Antacids Minor
Iron supplements Minor

🚨 Major Interactions

  • Antipsychotics (e.g., haloperidol, risperidone)
  • Drugs prolonging QT interval (e.g., amiodarone, sotalol)
  • Levodopa
  • Methotrexate

⚡ Moderate Interactions

  • Ketoconazole, itraconazole
  • Atazanavir, nelfinavir
  • Clopidogrel
  • Warfarin

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can increase the sedative effects of Levosulpiride, leading to excessive drowsiness, dizziness, and impaired coordination. It may also worsen gastrointestinal side effects and increase the risk of liver problems.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Levosulpiride, Pantoprazole, or any component of the formulation","Pheochromocytoma","Epilepsy","Parkinson's disease","Severe renal impairment (creatinine clearance < 20 mL/min)","Concomitant use with levodopa","Pregnancy and breastfeeding (unless clearly needed)"]

⚠️ Warnings & Precautions

["May cause drowsiness and dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine.","Use with caution in patients with cardiovascular disease or QT prolongation.","May increase prolactin levels; monitor for signs of hyperprolactinemia.","Long-term use of Pantoprazole may increase risk of bone fractures, hypomagnesemia, and vitamin B12 deficiency.","Do not crush, chew, or break the capsule; swallow whole.","Inform your doctor if you have liver or kidney disease.","Not recommended for children unless prescribed by a specialist."]

🤱 Lactation Safety

Not established from the available information. Levosulpiride and Pantoprazole may pass into breast milk. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

Overdose may cause severe drowsiness, dizziness, extrapyramidal symptoms, and cardiac arrhythmias. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if taken recently. Monitor vital signs and ECG.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the capsule; swallow it whole. It is best taken on an empty stomach, at least 30-60 minutes before breakfast, unless your doctor advises otherwise. Avoid alcohol while taking this medicine as it may increase drowsiness and dizziness. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you have a history of heart rhythm problems, liver disease, kidney disease, or Parkinson's disease. Do not stop this medicine abruptly without consulting your doctor. Keep out of reach of children. Store at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to side effects like drowsiness, dizziness, and extrapyramidal symptoms. They may also have reduced renal and hepatic function, requiring dose adjustments. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Both Levosulpiride and Pantoprazole should be used during pregnancy only if clearly needed. Discuss alternative treatments if necessary.

🏥 Post-Surgery Considerations

After surgery, the use of this medicine should be discussed with your surgeon. It may be continued if needed for acid suppression or motility, but caution is advised due to potential interactions with anesthetic agents and other postoperative medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with certain medications used during dental procedures. Also, dry mouth caused by this medicine may increase the risk of dental caries; maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce pressure on the stomach.
🥗
Avoid lying down immediately after meals; wait at least 2-3 hours.
😴
Eat smaller, more frequent meals to reduce acid reflux.
💧
Avoid trigger foods like spicy, fatty, and acidic foods.
🧘
Elevate the head of your bed while sleeping to prevent night-time reflux.
🌞
Quit smoking and limit alcohol consumption.

🏋️ Exercise Considerations

Avoid vigorous exercise immediately after taking this medicine, especially if you experience dizziness or drowsiness. Light to moderate exercise is generally safe, but listen to your body and stay hydrated.

🥗 Diet Recommendations

Include fiber-rich foods like fruits, vegetables, and whole grains.
Avoid spicy, fatty, and fried foods.
Limit caffeine and carbonated drinks.
Eat smaller, more frequent meals.
Stay well hydrated with water.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness and dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to take it in the morning to minimize interference with work, but consult your doctor for personalized advice.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or your symptoms resolve, your doctor may gradually reduce the dose or switch to an alternative. Abrupt discontinuation may cause rebound acid hypersecretion.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to vitamin B12 deficiency, hypomagnesemia, increased risk of bone fractures, and hyperprolactinemia. Regular monitoring of vitamin B12, magnesium, and prolactin levels may be advised. It is important to periodically review the need for continued therapy with your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet changes, weight loss, and elevating the head of the bed can help manage GERD symptoms.

Evidence: Well-established
Other prokinetics

Domperidone or metoclopramide may be used as alternatives, but they have their own side effect profiles.

Evidence: Moderate
Surgery

Fundoplication may be considered for severe GERD unresponsive to medication.

Evidence: Well-established for selected patients

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. However, long-term use of Pantoprazole may increase the risk of certain infections like pneumonia; ensure you are up to date with recommended vaccinations, including pneumococcal and influenza vaccines, as advised by your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust the dosing time to maintain a 24-hour interval, but consult your doctor for specific advice. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old man with chronic GERD and bloating
He was prescribed this medicine once daily before breakfast. After two weeks, his heartburn and bloating significantly reduced. He experienced mild drowsiness initially, which subsided after a few days. He was advised to avoid alcohol and driving until the effects were known.
💡 Lesson: Consistent use on an empty stomach and avoiding alcohol improves tolerability and efficacy.
👤 A 60-year-old woman with diabetic gastroparesis
She had nausea and early satiety. This medicine helped improve her gastric emptying and reduced nausea. She was monitored for extrapyramidal symptoms and renal function. She was advised to take it regularly and report any abnormal movements.
💡 Lesson: Regular monitoring and adherence are key to safe and effective treatment.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Levosulpiride may start working within 30-60 minutes, while Pantoprazole's full acid-suppressive effect may take a few days.

Q: Can I take it with food?

A: It is best taken on an empty stomach, at least 30-60 minutes before breakfast, as food may reduce the absorption of Pantoprazole.

Q: Is it safe for long-term use?

A: Long-term use should be under medical supervision due to potential risks like vitamin B12 deficiency, bone fractures, and hyperprolactinemia.

Q: What if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it's almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for gonta l 75mg/40mg capsule sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken as an antacid for immediate relief.
    Fact: This medicine is not for immediate relief; it works by reducing acid production over time and improving motility.
  • Myth: It is safe to take indefinitely without monitoring.
    Fact: Long-term use requires monitoring for potential side effects like vitamin B12 deficiency and bone fractures.
  • Myth: You can stop it abruptly once symptoms improve.
    Fact: Always consult your doctor before stopping, as abrupt discontinuation may cause rebound acid hypersecretion.

🔄 Alternative Options

Generic Alternatives

  • Levosulpiride + Pantoprazole combination (generic)

Brand Alternatives

  • Pantocid L
  • Levosulpiride + Pantoprazole brands

📊 Comparison with Similar Medicines

[{"medicine":"Pantoprazole + Domperidone","difference":"Domperidone is another prokinetic; may have different side effect profile."},{"medicine":"Rabeprazole + Levosulpiride","difference":"Rabeprazole is another PPI; similar efficacy but different metabolism."}]

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