Spasmogip Tablet - Dicyclomine (NA) + Paracetamol (NA) medicine

Koligesic Oral Suspension: Complete Medicine Guide

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🏭 Gipla Healthcare 📦 strip of 10 tablets 💊 Allopathy 📅 Updated: Oct 22, 2026
🤰 Pregnancy Category Consult your doctor before use. Dicyclomine is generally avoided in pregnancy unless clearly needed. Paracetamol is considered safe in pregnancy at recommended doses. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for individual components; combination evidence is limited.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is Spasmogip Tablet used for?

This medicine is a combination of dicyclomine and paracetamol used to treat abdominal cramps and spasms. It works by relaxing gut muscles and reducing pain.

  • Generic Name: Dicyclomine (NA) + Paracetamol (NA)
  • Manufacturer: Gipla Healthcare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Spasmogip Tablet के बारे में (Hindi Summary)

उपयोग: यह दवा पेट की ऐंठन, दर्द और सूजन में राहत देने के लिए इस्तेमाल की जाती है। यह आईबीएस और पेट की मरोड़ में भी फायदेमंद है।

साइड इफेक्ट्स: सूखा मुँह, चक्कर आना, नींद आना, धुंधली दृष्टि, जी मिचलाना और कब्ज जैसे दुष्प्रभाव हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। नींद आने पर वाहन न चलाएं। शराब न पिएं। यकृत या गुर्दे की बीमारी हो तो डॉक्टर को बताएं।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 Spasmogip Tablet Uses & Benefits

[{"condition":"Irritable bowel syndrome (IBS)","description":"Helps relieve abdominal cramps and pain associated with IBS by reducing smooth muscle spasms.","evidence":"Well-established"},{"condition":"Abdominal cramps","description":"Provides relief from spasmodic pain in the gastrointestinal tract.","evidence":"Well-established"},{"condition":"Gastrointestinal spasm","description":"Relaxes smooth muscles to alleviate spasm-related discomfort.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Menstrual cramps","description":"Sometimes used off-label to relieve dysmenorrhea due to antispasmodic and analgesic effects.","evidence":"Limited"}]

Primary treatment for: Irritable bowel syndrome

Also treats: Abdominal cramps, Gastrointestinal spasm

📋 Drug Information

Generic Name(s)Dicyclomine (NA) + Paracetamol (NA)
Brand NameSpasmogip Tablet
ManufacturerGipla Healthcare
Packaging / Formstrip of 10 tablets (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep out of reach of children.
Shelf Life24 months from date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Abdominal cramps
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDicyclomine is well absorbed from the gastrointestinal tract. Paracetamol is rapidly and completely absorbed from the gastrointestinal tract.
DistributionDicyclomine is distributed widely in the body, including the central nervous system. Paracetamol distributes throughout most body tissues.
Protein BindingDicyclomine is approximately 80% bound to plasma proteins. Paracetamol is minimally bound to plasma proteins.
MetabolismDicyclomine is metabolized in the liver. Paracetamol is metabolized primarily in the liver via glucuronidation and sulfation, with a small fraction oxidized by CYP2E1.
Half-LifeDicyclomine half-life is about 1.8 hours. Paracetamol half-life is 2-3 hours.
ExcretionDicyclomine is excreted mainly in urine and feces. Paracetamol is excreted in urine as metabolites.
BioavailabilityDicyclomine bioavailability is about 50-60%. Paracetamol bioavailability is approximately 80-100%.
Onset of ActionDicyclomine onset is within 1-2 hours. Paracetamol onset is within 30-60 minutes.
Peak Plasma TimeDicyclomine peak plasma time is 1-2 hours. Paracetamol peak plasma time is 0.5-2 hours.
Duration of ActionDicyclomine duration is 4-6 hours. Paracetamol duration is 4-6 hours.

How It Works

Dicyclomine acts as an anticholinergic and antispasmodic agent that blocks muscarinic receptors in the gastrointestinal tract, leading to relaxation of smooth muscle and reduction of spasms. Paracetamol works centrally to inhibit prostaglandin synthesis, thereby reducing pain and fever. The combination provides both antispasmodic and analgesic effects.

Mechanism Steps

1
Muscarinic receptor blockade: Dicyclomine binds to muscarinic receptors on smooth muscle cells, preventing acetylcholine from binding and causing contraction.
2
Smooth muscle relaxation: This blockade leads to relaxation of the gastrointestinal smooth muscle, reducing spasms and associated pain.
3
Central analgesia: Paracetamol acts on the central nervous system to inhibit prostaglandin synthesis, reducing pain perception and fever.

💡 How to Take Spasmogip Tablet

Strength: Each 5 mL contains dicyclomine hydrochloride 10 mg and paracetamol 250 mg (typical composition; actual strength may vary).

1Shake the bottle well before use.
2Measure the dose using the provided measuring cup or spoon.
3Take orally, with or without food.
4Follow the prescribed schedule.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is 10-20 mL of the suspension taken 3-4 times daily, as prescribed by a doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to side effects. Use with caution and adjust dose as needed under medical supervision.
Renal ImpairmentDose adjustment may be required in patients with renal impairment. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult a doctor.
Maximum Daily DoseDo not exceed 80 mL in 24 hours for adults, unless directed by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
May increase drowsiness and liver risk.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Spasmogip Tablet

✅ Common Side Effects

Dry mouth (Common (5-10%))
Sip water or chew sugarless gum. Consult doctor if persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Drowsiness (Common (5-10%))
Rest if needed. Avoid alcohol and other sedatives.
Blurred vision (Common (5-10%))
Usually temporary. Consult doctor if it persists.
Nausea (Common (5-10%))
Take with food or milk to reduce stomach upset.

🚨 Serious Side Effects

Allergic reactions (rash, itching, swelling, difficulty breathing) (Rare (<0.1%))
Seek immediate medical attention.
Irregular heartbeat (Rare (<0.1%))
Contact doctor immediately.
Severe skin reactions (Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop medicine and seek emergency care.

⚠️ Rare Side Effects

Hallucinations
Consult doctor immediately.
Blood dyscrasias
Report unusual bleeding or bruising.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
Warfarin Major
Antihistamines Moderate
Tricyclic antidepressants Moderate
Antacids Minor

🚨 Major Interactions

  • MAO inhibitors
  • Warfarin

⚡ Moderate Interactions

  • Antihistamines
  • Tricyclic antidepressants

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine as it can increase drowsiness and the risk of liver toxicity, especially due to paracetamol.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to dicyclomine or paracetamol","Glaucoma","Myasthenia gravis","Severe liver disease","Urinary retention","Gastrointestinal obstruction"]

⚠️ Warnings & Precautions

["Avoid driving or operating machinery if drowsy.","Do not exceed recommended dose due to risk of liver damage.","Use with caution in elderly patients.","Consult doctor if symptoms persist beyond 7 days.","Avoid alcohol."]

🤱 Lactation Safety

Dicyclomine may pass into breast milk and could affect the infant. Consult your doctor before breastfeeding.

💊 Overdose Management

Seek immediate medical attention. Overdose may cause severe liver damage from paracetamol and anticholinergic symptoms from dicyclomine. Treatment is supportive and may include activated charcoal and acetylcysteine for paracetamol toxicity.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery if you feel drowsy or dizzy. Avoid alcohol while taking this medicine as it may increase drowsiness and the risk of liver problems. Inform your doctor if you have a history of liver or kidney disease, glaucoma, or heart problems. Do not use this medicine for prolonged periods without medical supervision. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to side effects like dizziness, dry mouth, and urinary retention. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy. Dicyclomine is generally avoided in pregnancy unless clearly needed. Paracetamol is considered safe at recommended doses.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, as it may affect bowel movements and interact with other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and affect oral health.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce abdominal pressure.
🥗
Eat small, frequent meals to ease digestion.
😴
Avoid trigger foods like spicy or fatty meals.
💧
Practice stress-reducing techniques like yoga.
🧘
Stay physically active with light exercise.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel dizzy or drowsy. Light activities like walking are generally safe.

🥗 Diet Recommendations

Include fiber-rich foods
Avoid spicy and oily foods
Stay well hydrated

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Avoid such activities until you know how it affects you.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects, seek medical advice immediately.

📅 Long-Term Use Effects

Long-term use of this medicine should be under medical supervision. Prolonged use of paracetamol may increase the risk of liver damage, especially with alcohol. Dicyclomine may cause persistent dry mouth or constipation. Regular monitoring of liver and kidney function may be advised.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary changes

Avoiding trigger foods can help manage IBS symptoms.

Evidence: Well-established
Stress management

Yoga and meditation can reduce stress-related abdominal cramps.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Consult your doctor before any vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with IBS
She experienced frequent abdominal cramps and bloating. Her doctor prescribed this medicine. After a week, her cramps reduced significantly. She took it with food to avoid nausea.
💡 Lesson: Taking the medicine with food improves tolerability and compliance.
👤 A 50-year-old man with acute abdominal spasm
He had severe stomach cramps after eating out. The doctor gave this medicine. Relief came within an hour. He was advised to avoid alcohol and spicy food.
💡 Lesson: This medicine provides rapid relief from spasmodic pain.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 1-2 hours after taking it.

Q: Can I take it on an empty stomach?

A: It is best taken with food to reduce stomach upset.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Spasmogip Tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: It can cure IBS permanently.
    Fact: It provides symptomatic relief but does not cure IBS.
  • Myth: It is safe to take with alcohol.
    Fact: Alcohol increases the risk of side effects and liver damage.

🔄 Alternative Options

Generic Alternatives

  • Dicyclomine + Paracetamol suspension

Brand Alternatives

  • Koligesic Oral Suspension

📊 Comparison with Similar Medicines

[{"medicine":"Dicyclomine + Paracetamol","uses":"Abdominal cramps, IBS","side_effects":"Dry mouth, dizziness"},{"medicine":"Dicyclomine alone","uses":"Abdominal cramps","side_effects":"Dry mouth, dizziness"}]

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