Axpas Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain that does not improve
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output or inability to pass urine
- Fast or irregular heartbeat
- Confusion or hallucinations
If experiencing severe symptoms, call emergency services immediately.
What is cyclospaz tablet used for?
This medicine is a combination of dicyclomine and paracetamol used to relieve abdominal cramps and pain. Dicyclomine relaxes gut muscles, while paracetamol reduces pain and fever. It is usually taken one tablet one to three times a day with food, as prescribed by a doctor.
- Generic Name: Dicyclomine + Paracetamol
- Manufacturer: AGIO Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cyclospaz tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डाइसाइक्लोमिन और पैरासिटामोल का संयोजन है, जिसका उपयोग पेट की ऐंठन और दर्द को कम करने के लिए किया जाता है। डाइसाइक्लोमिन आंतों की मांसपेशियों को आराम देता है, जिससे ऐंठन कम होती है, और पैरासिटामोल दर्द और बुखार को कम करता है। यह दवा आमतौर पर इरिटेबल बाउल सिंड्रोम, पेट की ऐंठन, और पित्त नली की ऐंठन जैसी स्थितियों में डॉक्टर की सलाह पर दी जाती है। इसे भोजन के साथ या बाद में लेना चाहिए ताकि पेट में जलन न हो। इस दवा को बिना डॉक्टर की सलाह के लंबे समय तक नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुँह सूखना, धुंधली दृष्टि, चक्कर आना, नींद आना, जी मिचलाना और कब्ज शामिल हैं। कुछ लोगों को पेशाब करने में कठिनाई, दिल की धड़कन तेज होना, या त्वचा पर दाने भी हो सकते हैं। पैरासिटामोल अधिक मात्रा में लेने से लीवर को गंभीर नुकसान हो सकता है। अगर आपको आँखों या त्वचा का पीला पड़ना, गहरे रंग का पेशाब, या पेट में तेज दर्द हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और मात्रा न बढ़ाएँ। इसे पानी के साथ, भोजन के साथ या बाद में लें। अगर आपको चक्कर या नींद आ रही हो तो वाहन न चलाएँ और मशीन न चलाएँ। इस दवा के साथ शराब न पिएँ क्योंकि इससे नींद और लीवर की समस्या बढ़ सकती है। अगर आपको ग्लूकोमा, पेशाब की समस्या, लीवर या किडनी की बीमारी है, तो डॉक्टर को बताएँ। बच्चों की पहुँच से दूर रखें और ठंडी, सूखी जगह पर रखें।
💊 cyclospaz tablet Uses & Benefits
[{"condition":"Irritable bowel syndrome (IBS) with abdominal cramps","description":"This medicine helps relieve cramping and abdominal pain associated with irritable bowel syndrome by relaxing gastrointestinal smooth muscle and reducing pain perception.","evidence":"Well-established for symptomatic relief"},{"condition":"Functional gastrointestinal disorders with spasms","description":"It is used to ease painful spasms in conditions such as functional dyspepsia and non-ulcer dyspepsia when cramps are a prominent symptom.","evidence":"Moderate"},{"condition":"Biliary colic and other smooth muscle spasms","description":"Dicyclomine relaxes smooth muscle and may reduce pain in biliary or intestinal colic, while paracetamol provides additional analgesic effect.","evidence":"Limited to moderate"},{"condition":"Pain and fever associated with gastrointestinal infections","description":"Paracetamol in this combination helps reduce fever and general pain, while dicyclomine targets associated abdominal cramping.","evidence":"Supportive"}]
Off-label uses: [{"condition":"No established off-label uses","description":"There are no well-established off-label uses for this fixed-dose combination beyond its approved gastrointestinal antispasmodic and analgesic indications.","evidence":"Not established from the available information."}]
Primary treatment for: Irritable bowel syndrome with abdominal cramps
Also treats: Functional gastrointestinal disorders, Biliary colic, Gastrointestinal spasms, Pain and fever associated with gastrointestinal infections
📋 Drug Information
| Generic Name(s) | Dicyclomine + Paracetamol |
| Brand Name | Abdospas 20mg/500mg Tablet |
| Manufacturer | AGIO Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antispasmodic and Analgesic Combination |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C in a cool, dry place. Protect from direct sunlight and moisture. Keep the tablets in their original container or blister pack. |
| Shelf Life | Typically 24 to 36 months from the date of manufacture, depending on the manufacturer's packaging. Always check the expiry date on the pack before use. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different mechanisms. Dicyclomine is a synthetic antispasmodic that blocks muscarinic acetylcholine receptors on gastrointestinal smooth muscle, reducing muscle contractions and spasms. It also has a direct relaxant effect on smooth muscle. Paracetamol acts mainly in the central nervous system by inhibiting prostaglandin synthesis and modulating pain pathways, which reduces pain and fever. The combination provides both antispasmodic and analgesic effects for cramp-related abdominal pain.
Mechanism Steps
💡 How to Take cyclospaz tablet
Strength: Immediate-release oral tablet. The exact strength of dicyclomine and paracetamol in this product is not specified in the available information. Check the product label for the exact strength.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally one to three times a day, depending on the severity of symptoms and the prescriber's judgment. The exact strength of this product is not specified in the available information, so the dose must be confirmed from the product label. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the maximum recommended daily dose of paracetamol. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the anticholinergic effects of dicyclomine, such as confusion, dry mouth, constipation, and urinary retention. Use the lowest effective dose and monitor closely. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Dicyclomine may accumulate in patients with severe renal impairment. Use with caution and consider dose reduction. Paracetamol is generally safe in renal impairment at recommended doses. Dose must be individualized by a qualified clinician based on renal function. |
| Hepatic Impairment | Paracetamol should be used with caution in patients with hepatic impairment due to the risk of liver injury. Dicyclomine is metabolized in the liver and may require dose adjustment. Dose must be individualized by a qualified clinician based on hepatic function. |
| Maximum Daily Dose | The maximum daily dose of paracetamol should not exceed 4000 mg per day from all sources. The maximum daily dose of dicyclomine is typically 160 mg per day, but the exact limit for this combination product is not established from the available information. Always follow the prescriber's instructions. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cyclospaz tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other anticholinergics | Major | |
| Alcohol | Major | |
| Metoclopramide | Moderate | |
| Cholestyramine | Moderate | |
| Amantadine | Moderate | |
| Antacids | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- Other anticholinergic drugs (e.g., antihistamines, tricyclic antidepressants, antipsychotics)
- Warfarin
- Alcohol
⚡ Moderate Interactions
- Metoclopramide
- Cholestyramine
- Amantadine
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol increases the risk of liver damage from paracetamol and adds to the drowsiness and dizziness caused by dicyclomine. Chronic alcohol use further raises the risk of paracetamol-related hepatotoxicity.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to dicyclomine, paracetamol, or any component of this medicine","Glaucoma (narrow-angle)","Urinary retention or bladder neck obstruction","Myasthenia gravis","Severe liver disease or active liver failure","Paralytic ileus or intestinal obstruction","Severe ulcerative colitis or toxic megacolon","Breastfeeding without medical advice"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose of paracetamol; overdose can cause serious liver damage.","Avoid alcohol while taking this medicine.","Use with caution in elderly patients due to increased risk of anticholinergic effects.","Use with caution in patients with kidney or liver disease.","May cause drowsiness or blurred vision; avoid driving or operating machinery until you know how it affects you.","Do not use for prolonged periods without medical supervision.","Inform your doctor if you have heart disease, hypertension, or thyroid disorders.","Keep out of reach of children."]
🤱 Lactation Safety
Dicyclomine may pass into breast milk and could cause anticholinergic effects in a nursing infant. Paracetamol is considered safe during breastfeeding at recommended doses. This combination should be used during breastfeeding only if prescribed by a doctor, who will weigh the benefits and risks.
💊 Overdose Management
Overdose of this medicine can cause severe anticholinergic symptoms such as dry mouth, flushing, fast heartbeat, urinary retention, confusion, and seizures, as well as paracetamol-induced liver injury. If you suspect an overdose, seek emergency medical care immediately. Do not wait for symptoms to appear. Treatment may include activated charcoal, supportive care, and acetylcysteine for paracetamol toxicity. Carry the medicine container to the hospital.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor and do not exceed the recommended dose. Swallow the tablet with water, preferably with or after food, to reduce stomach upset. Avoid driving or operating heavy machinery if you feel dizzy or drowsy. Do not drink alcohol while taking this medicine because it can increase drowsiness and the risk of liver problems. Inform your doctor if you have glaucoma, an enlarged prostate, urinary problems, liver disease, kidney disease, or heart rhythm disorders. Do not use this medicine for more than a few days without medical advice. Keep it out of reach of children and store it in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the anticholinergic effects of dicyclomine, such as confusion, dry mouth, constipation, and urinary retention. They may also be more prone to liver and kidney problems from paracetamol. Use the lowest effective dose and monitor closely.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Paracetamol is generally considered safe, but dicyclomine should be used with caution, especially during the first trimester. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
After surgery, use this medicine only if prescribed by your doctor. It may interact with other medications used during recovery. Inform your surgeon and anesthesiologist about all medicines you are taking.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may interact with anesthetics or other medications used during dental work. Your dentist may advise you to stop it temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Mild to moderate exercise is generally safe while taking this medicine. However, if you feel dizzy, drowsy, or have blurred vision, avoid exercise that requires balance or coordination. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, dizziness, or blurred vision, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to inform your employer if your work involves operating heavy machinery.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within a few days, if they worsen, or if you experience any serious side effects. Do not stop a prescribed course without consulting your doctor, especially if you have an underlying condition being treated.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Prolonged use of dicyclomine can lead to persistent anticholinergic effects such as constipation, dry mouth, and urinary retention. Regular use of paracetamol at high doses can increase the risk of liver and kidney problems. Periodic monitoring of liver and kidney function may be advised. Do not use this medicine for longer than recommended without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Avoiding trigger foods and eating a balanced diet can help reduce abdominal cramps.
Evidence: Well-establishedYoga, meditation, and counseling can help reduce stress-related gastrointestinal symptoms.
Evidence: ModerateMay help improve gut health in some patients with irritable bowel syndrome.
Evidence: Limited to moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you have a fever, consult your doctor before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue with your regular dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines in your destination country. Keep enough supply for the duration of your trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Paracetamol starts relieving pain and fever within 30 to 60 minutes, while dicyclomine begins to relieve cramps within 1 to 2 hours.
A: Yes, it is best taken with or immediately after food to reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, alcohol should be avoided as it increases drowsiness and the risk of liver injury from paracetamol.
A: This medicine should be used during pregnancy only if prescribed by a doctor. Paracetamol is generally considered safe, but dicyclomine should be used with caution.
🤔 Common Patient Concerns
🔄 Substitutes for cyclospaz tablet
View AllAlternative brands with exact same active ingredient:
-
spasmokem tabletAlkem Laboratories Ltd ₹4.28 71.5% CHEAPER
-
spasmoban capsuleOverseas Healthcare Pvt Ltd ₹8.80 41.3% CHEAPER
-
spasmodex tabletSynchem Lab ₹14.28 4.8% CHEAPER
-
cycloceta tabletTheo Pharma Pvt Ltd ₹18.75 25% COSTLIER
-
Spasmogip TabletGipla Healthcare ₹20.00 33.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of stomach pain.
Fact: This medicine is specifically for cramp-related abdominal pain and is not suitable for all types of stomach pain. Consult a doctor for proper diagnosis. - Myth: It is safe to take extra tablets if the pain is severe.
Fact: Taking more than the recommended dose can cause serious side effects, especially liver damage from paracetamol. Always follow the prescribed dose. - Myth: This medicine can be taken long-term without any monitoring.
Fact: Long-term use should be monitored by a doctor, especially for liver and kidney function and anticholinergic side effects.
🔄 Alternative Options
Generic Alternatives
- Dicyclomine + Paracetamol generic tablets
Brand Alternatives
- Axpas Tablet