nimumac cold tablet - Phenylephrine (5mg) + Nimesulide (100mg) medicine

Nimumac Cold Tablet: Complete Medicine Guide

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🏭 Torque Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 23, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Use is not recommended, especially in the third trimester, due to risks to the fetus. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Limited evidence for the combination; individual components have established evidence.
Reviewed by
SaathiMed Expert Panel | Oct 23, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is nimumac cold tablet used for?

This medicine is a combination of Phenylephrine (a nasal decongestant) and Nimesulide (an NSAID) used for short-term relief of cold symptoms like nasal congestion, headache, and body ache. It should not be used for more than 5 days without medical advice.

  • Generic Name: Phenylephrine (5mg) + Nimesulide (100mg)
  • Manufacturer: Torque Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 nimumac cold tablet के बारे में (Hindi Summary)

उपयोग: यह दवा फेनिलएफ्रिन और नाइमेसुलाइड का संयोजन है, जिसका उपयोग सर्दी-जुकाम के लक्षणों जैसे नाक बंद होना, सिरदर्द, शरीर दर्द और बुखार से राहत के लिए किया जाता है। यह दवा केवल लक्षणों का इलाज करती है, बीमारी का नहीं। इसे 5 दिन से अधिक न लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द, चक्कर आना और रक्तचाप में वृद्धि शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, लीवर और किडनी की समस्या हो सकती है।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें। 5 दिन से अधिक इसका उपयोग न करें। यदि आपको उच्च रक्तचाप, हृदय, गुर्दे या यकृत की समस्या है तो डॉक्टर को बताएं।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 nimumac cold tablet Uses & Benefits

[{"condition":"Common cold with nasal congestion","description":"Provides symptomatic relief of nasal congestion, headache, body ache, and fever associated with the common cold.","evidence":"Established for short-term symptomatic relief"},{"condition":"Allergic rhinitis","description":"May help reduce nasal congestion and associated pain in allergic rhinitis.","evidence":"Limited evidence for this combination"},{"condition":"Sinusitis","description":"Used for short-term relief of sinus pressure and pain.","evidence":"Limited evidence for this combination"}]

Off-label uses: [{"condition":"Not established from the available information.","description":"Not established from the available information.","evidence":"Not established from the available information."}]

Primary treatment for: Common cold

Also treats: Allergic rhinitis, Sinusitis

📋 Drug Information

Generic Name(s)Phenylephrine (5mg) + Nimesulide (100mg)
Brand Namenimumac cold tablet
ManufacturerTorque Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Do not exceed the recommended dose or duration of 5 days.
3
Avoid alcohol while taking this medicine.
4
Monitor your blood pressure if you have hypertension.
5
Consult your doctor if symptoms persist beyond 5 days.
6
Report any unusual bleeding or bruising immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Nasal congestion
This medicine is commonly prescribed for this.
Likely Use
✅
Headache
This medicine can help relieve headache.
Likely Use
✅
Fever
This medicine has antipyretic properties.
Likely Use
❌
Chronic joint pain
This medicine is not intended for chronic pain.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionPhenylephrine is absorbed from the gastrointestinal tract but undergoes extensive first-pass metabolism, resulting in low oral bioavailability. Nimesulide is rapidly and extensively absorbed after oral administration.
DistributionPhenylephrine distribution is not well characterized. Nimesulide is highly protein-bound and distributes widely into body tissues, including synovial fluid.
Protein BindingPhenylephrine protein binding is not established from the available information. Nimesulide is approximately 99% bound to plasma proteins.
MetabolismPhenylephrine is metabolized in the liver by monoamine oxidase and other enzymes. Nimesulide is metabolized in the liver, primarily by CYP2C9, to several metabolites.
Half-LifePhenylephrine elimination half-life is approximately 2.5 to 3 hours. Nimesulide elimination half-life is approximately 1.8 to 4.7 hours.
ExcretionPhenylephrine is excreted in urine mainly as metabolites. Nimesulide is excreted primarily in urine and feces as metabolites.
BioavailabilityPhenylephrine oral bioavailability is low and variable, approximately 38% due to first-pass metabolism. Nimesulide oral bioavailability is approximately 70-80%.
Onset of ActionPhenylephrine onset of action is within 15-30 minutes after oral administration. Nimesulide onset of action is within 30-60 minutes.
Peak Plasma TimePhenylephrine peak plasma time is approximately 1-2 hours. Nimesulide peak plasma time is approximately 1.5-3 hours.
Duration of ActionPhenylephrine duration of action is approximately 4-6 hours. Nimesulide duration of action is approximately 6-8 hours.

How It Works

This medicine combines two active ingredients with different mechanisms. Phenylephrine is a selective alpha-1 adrenergic receptor agonist that causes vasoconstriction of nasal blood vessels, reducing swelling and congestion. Nimesulide is a non-steroidal anti-inflammatory drug that inhibits the cyclooxygenase-2 (COX-2) enzyme, thereby decreasing the production of prostaglandins, which are mediators of pain, inflammation, and fever.

Mechanism Steps

1
Alpha-1 adrenergic receptor activation: Phenylephrine binds to alpha-1 adrenergic receptors on vascular smooth muscle cells in the nasal mucosa, causing vasoconstriction.
2
Reduced nasal blood flow: Vasoconstriction decreases blood flow to the nasal mucosa, reducing swelling and congestion.
3
COX-2 enzyme inhibition: Nimesulide inhibits the COX-2 enzyme, blocking the conversion of arachidonic acid to prostaglandins.
4
Decreased prostaglandin synthesis: Lower prostaglandin levels reduce pain, inflammation, and fever.

💡 How to Take nimumac cold tablet

Strength: Tablet containing Phenylephrine 5 mg and Nimesulide 100 mg.

1Take the tablet with a glass of water.
2Take it after food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Do not exceed the recommended dose.
5Complete the prescribed course.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally 1 to 2 times daily, preferably after meals. The maximum recommended duration is 5 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. Use with caution and consult a doctor for appropriate dosing.
Renal ImpairmentUse with caution in patients with kidney impairment. Dose adjustment may be necessary. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with liver impairment. Dose adjustment may be necessary. Consult a doctor.
Maximum Daily DoseThe maximum recommended daily dose is 2 tablets (200 mg nimesulide and 10 mg phenylephrine). Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of nimumac cold tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk. Consult doctor if persistent.
Stomach pain (Common (5-10%))
Take with food. Avoid alcohol. Consult doctor if severe.
Headache (Common (5-10%))
Usually resolves. Consult doctor if persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Increased blood pressure (Uncommon (1-5%))
Monitor blood pressure. Consult doctor if elevated.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Liver damage (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe fatigue.
Kidney problems (Rare (<0.1%))
Seek medical attention if you notice decreased urine output or swelling.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if you experience swelling of face, lips, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Blood disorders
Consult doctor if you notice unusual bleeding or bruising.
Skin rash
Consult doctor if rash develops.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
MAOIs Major
ACE inhibitors Moderate
Diuretics Moderate
Beta-blockers Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs
  • Monoamine oxidase inhibitors (MAOIs)

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Beta-blockers

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding and liver damage.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to phenylephrine, nimesulide, or any component of the formulation","History of gastrointestinal bleeding or perforation related to NSAID use","Active peptic ulcer or bleeding","Severe liver impairment","Severe kidney impairment","Severe heart failure","Children under 12 years of age","Pregnancy (especially third trimester)","Breastfeeding"]

⚠️ Warnings & Precautions

["Do not exceed the recommended dose or duration of treatment.","Take with food to minimize stomach upset.","Avoid alcohol during treatment.","Use with caution in patients with hypertension, heart disease, or diabetes.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Consult a doctor if symptoms persist beyond 5 days."]

🤱 Lactation Safety

Not established from the available information. It is not known if this medicine passes into breast milk. Consult your doctor before use.

💊 Overdose Management

Seek immediate medical attention. Symptoms of overdose may include severe stomach pain, vomiting, rapid heartbeat, and difficulty breathing. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding. Do not take other NSAIDs or pain relievers without consulting your doctor. If you have high blood pressure, heart disease, kidney or liver problems, or diabetes, inform your doctor before taking this medicine. Do not use this medicine for more than 5 days unless directed by a doctor. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of side effects such as gastrointestinal bleeding, kidney problems, and increased blood pressure. Use with caution and under medical supervision.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy, especially in the third trimester, due to risks to the fetus. Consult your doctor for safe alternatives if you are planning pregnancy or are pregnant.

🏥 Post-Surgery Considerations

Consult your doctor before taking this medicine after surgery, as it may increase the risk of bleeding and interfere with healing.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may increase the risk of bleeding during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated by drinking plenty of fluids.
🥗
Get adequate rest to help your body recover.
😴
Use a humidifier to ease nasal congestion.
💧
Avoid exposure to cold and damp environments.
🧘
Wash your hands frequently to prevent spreading infections.

🏋️ Exercise Considerations

Avoid strenuous exercise while taking this medicine, especially if you experience dizziness or fatigue. Light activity is generally safe.

🥗 Diet Recommendations

Eat light, easily digestible meals.
Include warm soups and broths.
Avoid spicy and oily foods that can irritate the stomach.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to rest and avoid strenuous work while you are unwell.

🛑 When to Stop This Medicine

Stop taking this medicine if you experience any serious side effects such as severe stomach pain, blood in stool or vomit, yellowing of skin or eyes, or difficulty breathing. Consult your doctor before stopping if you have been taking it for more than 5 days.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended due to the risk of serious side effects such as liver damage, kidney problems, and gastrointestinal bleeding. It should only be used for short-term relief of cold symptoms.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Can help relieve nasal congestion naturally.

Evidence: Well-established for symptom relief.
Saline nasal spray

Helps moisturize and clear nasal passages.

Evidence: Well-established for symptom relief.

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information. Consult your doctor regarding vaccination timing if you are unwell.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with common cold and severe nasal congestion
He took this medicine as prescribed for 3 days. His nasal congestion and headache improved significantly. He experienced mild stomach upset, which was relieved by taking the medicine with food.
💡 Lesson: Taking this medicine with food improves tolerability and reduces stomach upset.
👤 A 50-year-old woman with a history of hypertension
She took this medicine for cold symptoms without consulting her doctor. Her blood pressure increased, and she experienced dizziness. She was advised to stop the medicine and consult her doctor.
💡 Lesson: Patients with hypertension should consult a doctor before taking this medicine due to the risk of blood pressure elevation.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30-60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best to take it with food to reduce stomach upset.

Q: Is it safe for children?

A: No, it is not recommended for children under 12 years of age.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for nimumac cold tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine only relieves symptoms; it does not cure the viral infection.
  • Myth: It is safe to take this medicine for long periods.
    Fact: Prolonged use can cause serious side effects like liver and kidney damage.

🔄 Alternative Options

Generic Alternatives

  • Phenylephrine + Nimesulide combination tablets from other manufacturers

Brand Alternatives

  • Nimumac Cold Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Paracetamol + Phenylephrine","difference":"Paracetamol is safer for the stomach but lacks anti-inflammatory effect."},{"medicine":"Ibuprofen + Phenylephrine","difference":"Ibuprofen is an NSAID similar to nimesulide but with different side effect profile."}]

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