entimin 2 mg/5 mg tablet - Chlorpheniramine Maleate (2mg) + Phenylephrine (5mg) medicine

Alycold Oral Suspension: Complete Medicine Guide

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🏭 Alde Medi Impex Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for allergic rhinitis and common cold.
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of the face, lips, tongue, or throat
  • Chest pain, rapid or irregular heartbeat
  • Severe headache, confusion, or hallucinations
  • Seizures or convulsions
  • Inability to urinate or severe abdominal pain
  • Yellowing of the skin or eyes (jaundice)
  • Unusual bleeding or bruising
  • Severe dizziness or fainting

If experiencing severe symptoms, call emergency services immediately.

What is entimin 2 mg/5 mg tablet used for?

This medicine is a combination of chlorpheniramine (an antihistamine) and phenylephrine (a decongestant) used to treat symptoms of allergies and the common cold, such as sneezing, runny nose, and nasal congestion. It works by blocking histamine and narrowing blood vessels in the nose. It may cause drowsiness, so avoid driving. Do not use with MAOIs. Consult a doctor if symptoms persist beyond 7 days.

  • Generic Name: Chlorpheniramine Maleate (2mg) + Phenylephrine (5mg)
  • Manufacturer: Alde Medi Impex Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 entimin 2 mg/5 mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी और सर्दी-जुकाम के लक्षणों जैसे छींक, नाक बहना, नाक बंद होना और आंखों में खुजली के इलाज के लिए इस्तेमाल की जाती है। इसमें क्लोरफेनिरामाइन (एंटीहिस्टामिन) और फेनिलएफ्रिन (डिकंजेस्टेंट) होते हैं। यह नाक की रक्त वाहिकाओं को सिकोड़कर जमाव को कम करती है और हिस्टामिन को ब्लॉक करके एलर्जी के लक्षणों को कम करती है। यह दवा नींद ला सकती है, इसलिए वाहन चलाने से बचें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि और पेट खराब होना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें तेज धड़कन, दौरे, मतिभ्रम या पेशाब करने में कठिनाई हो सकती है। यदि आपको कोई गंभीर दुष्प्रभाव महसूस हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को बताएं यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड, ग्लूकोमा या पेशाब करने में कठिनाई है। यदि आप MAOI दवाएं ले रहे हैं तो इस दवा का सेवन न करें। शराब और अन्य नींद लाने वाली दवाओं से बचें। यह दवा वाहन चलाने या मशीनरी चलाने की क्षमता को प्रभावित कर सकती है। अनुशंसित खुराक से अधिक न लें। यदि लक्षण 7 दिनों से अधिक रहते हैं तो डॉक्टर से मिलें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 entimin 2 mg/5 mg tablet Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy watery eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief of nasal congestion, sneezing, and runny nose due to viral upper respiratory infections.","evidence":"Well-established"},{"condition":"Sinusitis","description":"Helps reduce nasal congestion and pressure associated with sinus inflammation.","evidence":"Supportive"},{"condition":"Otitis media with effusion","description":"Sometimes used as an adjunct to reduce congestion and improve Eustachian tube function, but evidence is limited.","evidence":"Limited"}]

Off-label uses: [{"condition":"Urticaria","description":"Chlorpheniramine may be used off-label for relief of itching and hives, but the combination with phenylephrine is not typically indicated for this purpose.","evidence":"Limited"},{"condition":"Motion sickness","description":"Chlorpheniramine has antiemetic properties and may be used off-label for motion sickness, but phenylephrine is not helpful for this indication.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Common cold, Sinusitis, Otitis media with effusion

📋 Drug Information

Generic Name(s)Chlorpheniramine Maleate (2mg) + Phenylephrine (5mg)
Brand Nameentimin 2 mg/5 mg tablet
ManufacturerAlde Medi Impex Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Do not freeze. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Avoid driving or operating heavy machinery until you know how this medicine affects you.
3
Do not drink alcohol while taking this medicine as it can increase drowsiness.
4
Use a calibrated measuring cup or syringe to ensure accurate dosing.
5
Do not exceed the recommended dose or frequency.
6
Consult your doctor if symptoms persist beyond 7 days or worsen.
7
Inform your doctor if you have high blood pressure, heart disease, or diabetes before taking this medicine.
8
Keep out of reach of children and store in a cool, dry place.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Runny nose
This medicine is commonly used for this symptom.
Likely Use
Sneezing
This medicine is commonly used for this symptom.
Likely Use
Nasal congestion
This medicine is commonly used for this symptom.
Likely Use
Itchy, watery eyes
This medicine is commonly used for this symptom.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Body ache
This medicine is not indicated for body ache.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorpheniramine maleate is well absorbed from the gastrointestinal tract after oral administration. Phenylephrine is also absorbed orally but undergoes extensive first-pass metabolism, resulting in reduced systemic bioavailability. The oral suspension is designed for rapid absorption.
DistributionChlorpheniramine is widely distributed throughout the body, including the central nervous system. Phenylephrine distribution is not well characterized but is expected to distribute to vascular tissues. Both drugs may cross the placenta and are excreted in breast milk.
Protein BindingChlorpheniramine is approximately 70% bound to plasma proteins. Phenylephrine protein binding is not well established.
MetabolismChlorpheniramine is metabolized in the liver, primarily by cytochrome P450 enzymes, including CYP2D6 and CYP3A4. Phenylephrine is metabolized by monoamine oxidase in the liver and gut wall.
Half-LifeChlorpheniramine: 12-43 hours; Phenylephrine: 2-3 hours
ExcretionChlorpheniramine and its metabolites are excreted primarily in the urine. Phenylephrine is excreted in the urine as unchanged drug and metabolites.
BioavailabilityChlorpheniramine: approximately 25-50% due to first-pass metabolism; Phenylephrine: approximately 38% due to extensive first-pass metabolism.
Onset of ActionChlorpheniramine: 30-60 minutes; Phenylephrine: 15-30 minutes
Peak Plasma TimeChlorpheniramine: 2-6 hours; Phenylephrine: 1-2 hours
Duration of ActionChlorpheniramine: 4-6 hours; Phenylephrine: 4-6 hours

How It Works

This medicine combines an antihistamine and a decongestant. Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, thereby reducing allergic symptoms such as sneezing, runny nose, and itching. Phenylephrine is a sympathomimetic amine that primarily stimulates alpha-1 adrenergic receptors, causing vasoconstriction in the nasal mucosa, which reduces swelling and congestion. The combination provides relief from both allergic and congestive symptoms.

Mechanism Steps

1
Histamine H1 receptor blockade: Chlorpheniramine binds to H1 receptors on effector cells, preventing histamine from triggering allergic responses such as sneezing, itching, and vasodilation.
2
Alpha-1 adrenergic receptor stimulation: Phenylephrine stimulates alpha-1 receptors on vascular smooth muscle in the nasal mucosa, causing vasoconstriction and reduced blood flow, which decreases swelling and congestion.
3
Anticholinergic effects: Chlorpheniramine also blocks muscarinic acetylcholine receptors, leading to reduced secretions and dryness of the mouth, nose, and throat.
4
Central nervous system depression: Chlorpheniramine crosses the blood-brain barrier and causes sedation by blocking histamine in the central nervous system.

💡 How to Take entimin 2 mg/5 mg tablet

Strength: Each 5 mL of oral suspension contains Chlorpheniramine Maleate 2 mg and Phenylephrine 5 mg.

1Shake the bottle well before each use.
2Use a calibrated measuring device (dosing cup or syringe) to measure the dose accurately.
3Take the medicine orally, with or without food.
4If stomach upset occurs, take with food or milk.
5Do not exceed the recommended dose.
6Follow your doctor's instructions exactly.

Dosage Information

Adult DosageThe typical adult dose of this medicine is 10 mL (2 teaspoons) every 4 to 6 hours as needed, not to exceed 6 doses in 24 hours. However, the dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to therapy. Do not exceed the recommended dose. Follow your doctor's instructions exactly.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients (65 years and older) may be more sensitive to the effects of this medicine, especially drowsiness, dizziness, and anticholinergic effects. Use with caution and consider lower doses. Consult a doctor for individualized dosing.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor for individualized dosing.
Maximum Daily DoseFor adults: Maximum 6 doses (60 mL) in 24 hours. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals or milk
Reduces stomach upset.
Alcohol
Avoid
Increases drowsiness and CNS depression.
Grapefruit juice
Avoid
May increase drug levels.
Caffeine
Limit
May increase stimulant effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of entimin 2 mg/5 mg tablet

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery until you know how this medicine affects you. If drowsiness persists, consult your doctor.
Dry mouth, nose, or throat (Common (5-15%))
Sip water frequently, chew sugarless gum, or use a humidifier. Consult doctor if severe.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid sudden movements. Consult doctor if persistent.
Nausea or upset stomach (Common (5-10%))
Take with food or milk to reduce stomach upset. Consult doctor if severe.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if headache is severe or persistent.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, lips, tongue, or throat, difficulty breathing, or chest tightness.
Rapid or irregular heartbeat (Rare (<0.1%))
Seek immediate medical attention if you notice palpitations or irregular pulse.
Hallucinations or seizures (Rare (<0.1%))
Seek immediate medical attention if you experience hallucinations, confusion, or seizures.
Difficulty urinating (Rare (<0.1%))
Consult a doctor if you have trouble urinating or cannot urinate.
Severe hypertension (Rare (<0.1%))
Seek immediate medical attention if you experience severe headache, blurred vision, or chest pain.

⚠️ Rare Side Effects

Blood dyscrasias (e.g., agranulocytosis, thrombocytopenia)
Report unusual bruising, bleeding, or signs of infection to your doctor immediately.
Hepatotoxicity
Report yellowing of skin or eyes, dark urine, or abdominal pain to your doctor.
Photosensitivity
Use sunscreen and protective clothing when outdoors.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Tricyclic antidepressants Major
Beta-blockers Major
CNS depressants Moderate
Anticholinergics Moderate
Digoxin Moderate
Caffeine Minor
Antacids Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants
  • Beta-blockers

⚡ Moderate Interactions

  • Central nervous system depressants (e.g., alcohol, benzodiazepines, opioids)
  • Anticholinergic drugs (e.g., atropine, benztropine)
  • Digoxin

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and impair motor skills. Combined use may also increase the risk of central nervous system depression and respiratory depression.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to chlorpheniramine, phenylephrine, or any component of the formulation","Concurrent use with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping MAOIs","Severe hypertension or coronary artery disease","Narrow-angle glaucoma","Urinary retention due to prostatic hypertrophy","Severe hepatic or renal impairment"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","Use with caution in patients with cardiovascular disease, hypertension, diabetes, thyroid disorders, or glaucoma.","Do not exceed recommended dose.","Consult a doctor if symptoms persist beyond 7 days or are accompanied by fever.","Keep out of reach of children.","Elderly patients may be more sensitive to side effects.","Pregnant or breastfeeding women should consult a doctor before use."]

🤱 Lactation Safety

Chlorpheniramine and phenylephrine are excreted in breast milk. Caution is advised. Consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, seizures, hallucinations, hypertension, tachycardia, and respiratory depression. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, glaucoma, or difficulty urinating due to an enlarged prostate. Do not use this medicine if you are taking a monoamine oxidase inhibitor (MAOI) or have taken one in the last 14 days. Avoid alcohol and other central nervous system depressants while taking this medicine, as they can increase drowsiness. This medicine may impair your ability to drive or operate machinery. Do not exceed the recommended dose. If symptoms persist for more than 7 days or are accompanied by a fever, consult a doctor. Keep out of reach of children. Pregnant or breastfeeding women should consult a doctor before use.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more susceptible to the anticholinergic and sedative effects of this medicine. They may also be more prone to dizziness, falls, and urinary retention. Use with caution and consider lower doses. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant or are pregnant, consult your doctor before taking this medicine. The safety of this combination during pregnancy has not been fully established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

After surgery, use this medicine with caution as it may interact with anesthetics and other medications. Consult your surgeon or anesthesiologist before use.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with local anesthetics or other medications used during dental procedures. It may also cause dry mouth, which can affect oral health.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated by drinking plenty of fluids.
🥗
Get adequate rest to help your body recover.
😴
Use a humidifier to keep nasal passages moist.
💧
Avoid allergens such as dust, pollen, and pet dander.
🧘
Wash your hands frequently to prevent infections.
🌞
Avoid alcohol and caffeine while taking this medicine.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness, which can affect your coordination. Avoid strenuous exercise or activities that require mental alertness until you know how the medicine affects you.

🥗 Diet Recommendations

Drink warm fluids like soups and teas to soothe your throat.
Include vitamin C-rich foods to support immune function.
Avoid spicy and acidic foods if you have a sore throat.
Limit caffeine and alcohol.
Eat a balanced diet to support overall health.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may impair your ability to drive, operate machinery, or perform tasks requiring alertness. It is advisable to avoid such activities until you know how the medicine affects you. If your work requires mental alertness, discuss with your doctor about timing the dose or alternative options.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it regularly for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance, dependence, and increased risk of side effects such as drowsiness, dry mouth, and urinary retention. It is not intended for prolonged use without medical supervision. If you need to use it for more than 7 days, consult your doctor. Regular monitoring of blood pressure and heart rate may be necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Helps clear nasal passages and reduce congestion without medication.

Evidence: Well-established
Steam inhalation

Can temporarily relieve nasal congestion.

Evidence: Supportive
Antihistamine nasal sprays

Alternative for allergic rhinitis with fewer systemic side effects.

Evidence: Well-established
Allergen avoidance

Reducing exposure to allergens can decrease symptoms.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are acutely ill with a fever, it is generally recommended to postpone vaccination until you recover. Consult your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep in original container with cap tightly closed

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight and moisture

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Keep out of reach of children

❌ DON'T

Do not use after expiration date

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, adjust your dosing schedule accordingly, but do not take more than the maximum daily dose. Check local customs regulations regarding carrying medications. Always keep it in your carry-on luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergies
She was prescribed this medicine for her sneezing, runny nose, and itchy eyes. She took it as directed and experienced significant relief within 30 minutes. However, she felt drowsy, so she avoided driving. She learned to take it at bedtime to manage symptoms without daytime sedation.
💡 Lesson: This medicine is effective for allergy symptoms but can cause drowsiness. Adjusting the timing can help manage side effects.
👤 A 50-year-old man with a common cold
He used this medicine for nasal congestion and sneezing. He took it every 6 hours but exceeded the recommended dose because he wanted faster relief. He experienced dizziness and palpitations and had to seek medical help. He was advised to follow the dosing instructions strictly.
💡 Lesson: Do not exceed the recommended dose. Taking more can lead to serious side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts to work within 30 to 60 minutes after taking a dose.

Q: How long do the effects last?

A: The effects typically last for 4 to 6 hours, so it may need to be taken every 4 to 6 hours as needed.

Q: Can I take this medicine with other cold medicines?

A: You should avoid taking other cold medicines that contain similar ingredients (antihistamines or decongestants) to prevent overdose. Consult your doctor or pharmacist before combining.

Q: Is this medicine safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician for appropriate use in children.

Q: Can I take this medicine if I am pregnant?

A: Consult your doctor before use. The combination should be used during pregnancy only if clearly needed.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my blood pressure?
  • Can I drive after taking this medicine?
  • Does it interact with my other medications?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe for children?
  • Is it safe during pregnancy?

🔄 Substitutes for entimin 2 mg/5 mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection.
  • Myth: It is safe to take more than the recommended dose for faster relief.
    Fact: Taking more than the recommended dose can lead to serious side effects and is not safe.
  • Myth: This medicine is safe for everyone.
    Fact: It is not safe for individuals with certain conditions such as severe hypertension, coronary artery disease, or those taking MAOIs.
  • Myth: It is okay to drink alcohol while taking this medicine.
    Fact: Alcohol can increase drowsiness and other side effects and should be avoided.

🔄 Alternative Options

Generic Alternatives

  • Chlorpheniramine + Phenylephrine oral suspension (generic)

Brand Alternatives

  • Alycold Oral Suspension

📊 Comparison with Similar Medicines

[{"medicine":"Chlorpheniramine + Phenylephrine","sedation":"High","decongestant":"Phenylephrine","duration":"4-6 hours"},{"medicine":"Cetirizine + Phenylephrine","sedation":"Low","decongestant":"Phenylephrine","duration":"12-24 hours"},{"medicine":"Loratadine + Pseudoephedrine","sedation":"Low","decongestant":"Pseudoephedrine","duration":"12-24 hours"}]

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