Procold Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Irregular heartbeat or palpitations
If experiencing severe symptoms, call emergency services immediately.
What is procold tablet used for?
This medicine is a combination of Paracetamol and Phenylephrine used for temporary relief of common cold symptoms such as nasal congestion, headache, body ache, and mild fever. It works by reducing pain and fever and shrinking nasal blood vessels to ease congestion.
- Generic Name: Paracetamol (325mg) + Phenylephrine (5mg)
- Manufacturer: Concept Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 procold tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पैरासिटामोल और फेनाइलएफ्रिन का संयोजन है, जिसका उपयोग सर्दी-जुकाम, नाक बंद होना, सिरदर्द, शरीर दर्द और हल्के बुखार से राहत पाने के लिए किया जाता है। यह दवा नाक की रक्त वाहिकाओं को सिकोड़कर जमाव को कम करती है और दर्द तथा बुखार को कम करती है। इसका उपयोग केवल अल्पकालिक उपचार के लिए किया जाना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, पेट में परेशानी, सिरदर्द, चक्कर आना, घबराहट और रक्तचाप में वृद्धि शामिल हैं। दुर्लभ मामलों में गंभीर एलर्जी, यकृत क्षति, या हृदय संबंधी समस्याएं हो सकती हैं। यदि आपको कोई गंभीर लक्षण महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें। पैरासिटामोल युक्त अन्य दवाओं के साथ इसका सेवन न करें। शराब का सेवन पूरी तरह बंद कर दें। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड, ग्लूकोमा, या यकृत/गुर्दे की बीमारी है, तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से परामर्श लें।
💊 procold tablet Uses & Benefits
[{"condition":"Common cold","description":"Provides symptomatic relief from nasal congestion, headache, body ache, and mild fever associated with the common cold.","evidence":"Well-established"},{"condition":"Influenza-like illness","description":"Helps reduce fever, muscle pain, and nasal stuffiness during flu-like viral infections.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"May temporarily relieve nasal congestion and sinus pressure in allergic rhinitis, though antihistamines are preferred.","evidence":"Limited"},{"condition":"Sinusitis","description":"Used as an adjunct to reduce nasal mucosal inflammation" class="semantic-link" title="Medicines for swelling">swelling and relieve sinus headache and facial pain.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Eustachian tube dysfunction","description":"Occasionally used off-label to reduce mucosal swelling and improve ear pressure equalization.","evidence":"Limited"},{"condition":"Barotrauma prevention","description":"Sometimes used before air travel to reduce nasal congestion and prevent ear barotrauma in susceptible individuals.","evidence":"Limited"}]
Primary treatment for: Common cold
Also treats: Influenza-like illness, Allergic rhinitis, Sinusitis
📋 Drug Information
| Generic Name(s) | Paracetamol (325mg) + Phenylephrine (5mg) |
| Brand Name | procold tablet |
| Manufacturer | Concept Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Keep away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Paracetamol acts centrally to reduce fever and pain by inhibiting prostaglandin synthesis in the hypothalamus and spinal cord, and it may also modulate descending serotonergic pathways. Phenylephrine is a direct-acting sympathomimetic amine that selectively stimulates alpha-1 adrenergic receptors on vascular smooth muscle in the nasal mucosa, causing vasoconstriction, which reduces blood flow, edema, and nasal congestion. The combination provides symptomatic relief of cold-related pain, fever, and nasal stuffiness.
Mechanism Steps
💡 How to Take procold tablet
Strength: Each tablet contains Paracetamol 325 mg and Phenylephrine 5 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally every 6 to 8 hours as needed for symptoms, not exceeding 4 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose or duration without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the cardiovascular effects of Phenylephrine and the hepatic effects of Paracetamol. Use with caution and under medical supervision. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment may be required in patients with renal impairment. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Dose adjustment and careful monitoring are required in patients with hepatic impairment. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | Maximum daily dose is 4 tablets in 24 hours (1300 mg Paracetamol and 20 mg Phenylephrine). Do not exceed this limit. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of procold tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Tricyclic antidepressants | Major | |
| Warfarin | Major | |
| Beta-blockers | Moderate | |
| Digoxin | Moderate | |
| Ergot alkaloids | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor | |
| Caffeine | Minor | |
| Alcohol | Major |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants
- Warfarin
⚡ Moderate Interactions
- Beta-blockers
- Digoxin
- Ergot alkaloids
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine. Alcohol increases the risk of Paracetamol-induced liver damage and may worsen the cardiovascular effects of Phenylephrine, such as increased heart rate and blood pressure.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe hypertension","Severe coronary artery disease","Hyperthyroidism","Closed-angle glaucoma","Concurrent use of monoamine oxidase inhibitors (MAOIs)","Severe liver disease","Known hypersensitivity to Paracetamol or Phenylephrine"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose of Paracetamol; overdose can cause severe liver damage.","Avoid using other Paracetamol-containing products concurrently.","Use with caution in patients with cardiovascular disease, hypertension, or diabetes.","Phenylephrine may cause rebound nasal congestion if used for more than 3 days.","Avoid alcohol while taking this medicine.","Consult a doctor before use in pregnancy, breastfeeding, or in children under 12 years.","Do not use for more than 5 days without medical advice."]
🤱 Lactation Safety
Paracetamol is excreted in breast milk in small amounts and is generally considered safe during breastfeeding. Phenylephrine may reduce breast milk production and is not preferred during breastfeeding. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage due to Paracetamol and hypertensive crisis due to Phenylephrine. Seek emergency medical attention immediately. Treatment includes gastric lavage if within 1-2 hours, administration of N-acetylcysteine as an antidote for Paracetamol toxicity, and supportive care for cardiovascular effects. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of use. Avoid taking other products containing Paracetamol while on this medicine to prevent accidental overdose and liver injury. Do not use this medicine for more than 3 days for fever or 5 days for pain without consulting a doctor. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, glaucoma, or liver or kidney disease. Avoid alcohol completely while taking this medicine. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Keep this medicine out of reach of children. Store in a cool, dry place away from direct sunlight. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the cardiovascular effects of Phenylephrine and the hepatic effects of Paracetamol. Use with caution and under medical supervision. Dose adjustment may be required.
🤰 Pregnancy Planning (TTC)
Consult your doctor before using this medicine if you are planning pregnancy. Paracetamol is generally considered safe, but Phenylephrine should be used with caution, especially in the first trimester.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine after surgery, as it may interact with other medications or affect blood pressure and healing.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may interact with anesthetics or other medications used during dental work.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while taking this medicine, especially if you experience dizziness or increased heart rate. Light activities like walking are generally safe. Consult your doctor before resuming intense workouts.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or nervousness, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how this medicine affects you. It is generally safe to continue desk work.
🛑 When to Stop This Medicine
Stop this medicine if your symptoms improve or after 5 days of use, whichever is earlier. If symptoms persist or worsen, consult your doctor. Do not stop abruptly if you have been taking it for a prolonged period without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of Paracetamol can increase the risk of liver damage, especially with alcohol consumption. Phenylephrine used for more than 3 days can cause rebound nasal congestion. Regular monitoring of liver function and blood pressure may be required if used for extended periods under medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps relieve nasal congestion naturally.
Evidence: Well-establishedMoisturizes nasal passages and reduces congestion.
Evidence: Well-establishedSupports the body's natural recovery from cold.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before receiving any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue your regular dosing schedule as advised by your doctor. Check customs regulations for carrying medications in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts relieving symptoms within 30-60 minutes after oral administration.
A: Do not take other Paracetamol-containing products concurrently to avoid overdose. Consult your doctor before combining with other cold medicines.
A: Phenylephrine can increase blood pressure. Patients with hypertension should use this medicine with caution and under medical supervision.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection. - Myth: It is safe to take extra doses for faster relief.
Fact: Taking more than the recommended dose can cause serious liver damage and cardiovascular effects. - Myth: This medicine is safe for everyone.
Fact: It is not safe for people with certain conditions like severe hypertension, heart disease, or liver disease.
🔄 Alternative Options
Generic Alternatives
- Paracetamol 325 mg + Phenylephrine 5 mg tablet