Ambiac N 300mg/30mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or severe wheezing
- Swelling of face, lips, or throat
- Severe skin rash with blisters or peeling
- Blood in vomit or black, tarry stools
- Chest pain or palpitations
- High fever with chills
- Confusion or extreme drowsiness
If experiencing severe symptoms, call emergency services immediately.
What is nacfil ab tablet used for?
This medicine is a combination of acetylcysteine and ambroxol, used to treat thick mucus in respiratory conditions like bronchitis and COPD. It works by thinning mucus and making it easier to cough out. It is usually taken 2-3 times daily as prescribed.
- Generic Name: Acetylcysteine (300mg) + Ambroxol (30mg)
- Manufacturer: Fourrts India Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nacfil ab tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एसिटाइलसिस्टीन और एम्ब्रोक्सोल का संयोजन है, जिसका उपयोग ब्रोंकाइटिस, सीओपीडी और अन्य श्वसन रोगों में गाढ़े बलगम को पतला करने और खांसी के माध्यम से बाहर निकालने में मदद करने के लिए किया जाता है। यह बलगम को पतला करती है और सांस लेने में आसानी प्रदान करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट खराब, दस्त, और सीने में जलन शामिल हैं। कभी-कभी एलर्जी, चकत्ते, सांस लेने में कठिनाई, या गंभीर त्वचा प्रतिक्रियाएं हो सकती हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ या बिना भोजन के ले सकते हैं, लेकिन पेट की परेशानी से बचने के लिए भोजन के साथ लेना बेहतर है। अस्थमा के रोगी सावधानी बरतें और अपना इनहेलर पास रखें। 14 दिनों से अधिक इसका उपयोग बिना डॉक्टर की सलाह के न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से परामर्श करें। शराब का सेवन न करें।
💊 nacfil ab tablet Uses & Benefits
[{"condition":"Acute bronchitis","description":"Helps loosen thick mucus in the airways, making it easier to cough out and relieving chest congestion.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Used to manage chronic mucus hypersecretion and reduce exacerbations in chronic bronchitis patients.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"May help in thinning mucus and improving mucus clearance in COPD patients with thick secretions.","evidence":"Moderate"},{"condition":"Bronchiectasis","description":"Used as a mucolytic to help clear excessive mucus in bronchiectasis.","evidence":"Limited"},{"condition":"Cystic fibrosis","description":"Acetylcysteine is used as a mucolytic in cystic fibrosis, but the combination with ambroxol is not standard.","evidence":"Limited"}]
Off-label uses: [{"condition":"Prevention of contrast-induced nephropathy","description":"Acetylcysteine has been studied for preventing kidney damage from contrast dyes, but evidence is mixed and not for this combination.","evidence":"Limited"},{"condition":"Acetaminophen overdose","description":"Acetylcysteine is the antidote for acetaminophen poisoning, but this combination tablet is not used for that purpose.","evidence":"Well-established for acetylcysteine alone"}]
Primary treatment for: Respiratory conditions with thick mucus (e.g., bronchitis, COPD)
Also treats: Bronchiectasis, Cystic fibrosis, Sinusitis
📋 Drug Information
| Generic Name(s) | Acetylcysteine (300mg) + Ambroxol (30mg) |
| Brand Name | nacfil ab tablet |
| Manufacturer | Fourrts India Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two mucoactive agents. Acetylcysteine is a mucolytic that breaks disulfide bonds in mucoproteins, reducing mucus viscosity. Ambroxol is a mucolytic and expectorant that increases serous bronchial secretion, reduces mucus viscosity, and stimulates surfactant production. Together, they enhance mucus clearance and ease breathing.
Mechanism Steps
💡 How to Take nacfil ab tablet
Strength: Tablet containing acetylcysteine 300 mg and ambroxol 30 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet (acetylcysteine 300 mg + ambroxol 30 mg) two to three times daily, or as prescribed by your doctor. The dose may be adjusted based on your condition and response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients, but caution is advised due to potential reduced liver and kidney function. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with severe kidney impairment. Dose adjustment may be necessary. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with severe liver impairment. Dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 3 tablets (acetylcysteine 900 mg + ambroxol 90 mg) per day, unless otherwise prescribed by a doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nacfil ab tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Nitroglycerin | Major | |
| Codeine | Major | |
| Amoxicillin | Moderate | |
| Dextromethorphan | Moderate | |
| Activated charcoal | Minor |
🚨 Major Interactions
- Nitroglycerin
- Cough suppressants (e.g., codeine)
⚡ Moderate Interactions
- Antibiotics (e.g., amoxicillin, tetracycline)
- Antitussives (e.g., dextromethorphan)
🍷 Alcohol Interaction
Alcohol may increase the risk of stomach irritation and gastrointestinal bleeding. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to acetylcysteine, ambroxol, or any component of the formulation.","Active peptic ulcer disease.","Severe liver disease.","Severe kidney disease.","Children under 12 years (unless prescribed by a doctor)."]
⚠️ Warnings & Precautions
["Use with caution in patients with asthma; may cause bronchospasm.","Avoid use in patients with active peptic ulcer.","Use with caution in patients with severe liver or kidney impairment.","Do not use for more than 14 days without medical advice.","May cause drowsiness; avoid driving if affected.","Do not use cough suppressants concurrently.","Separate from antibiotics by at least 2 hours."]
🤱 Lactation Safety
Acetylcysteine and ambroxol are excreted in breast milk. It is not known if they are safe for the breastfed infant. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause nausea, vomiting, and diarrhea. Seek immediate medical attention. Treatment is symptomatic and supportive. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. Swallow the tablet whole with a glass of water. It can be taken with or without food, but taking it with food may reduce stomach upset. If you have asthma, use this medicine with caution and keep your rescue inhaler handy. Do not use this medicine for more than 14 days without consulting your doctor. Avoid alcohol while taking this medicine as it may increase stomach irritation. If you are pregnant or breastfeeding, consult your doctor before taking this medicine. Do not share this medicine with others, even if they have similar symptoms. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to side effects. Use with caution and monitor for stomach upset and drowsiness. Dose adjustment may be needed based on liver and kidney function.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy or if you become pregnant while taking this medicine. The safety of this combination during pregnancy is not well established.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with certain medications used during surgery.
🦷 Dental Procedures
No specific precautions for dental procedures. However, inform your dentist about all medicines you take.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you have difficulty breathing. Gentle activities like walking may help. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness in some people. Avoid driving or operating heavy machinery if you feel drowsy. It does not usually affect your ability to work, but take precautions.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects, allergic reactions, or if your symptoms do not improve within 14 days. Do not stop abruptly if you have been on long-term therapy without medical advice.
📅 Long-Term Use Effects
Long-term use beyond 14 days is not recommended without medical supervision. Prolonged use may lead to gastrointestinal discomfort. Regular monitoring of liver and kidney function may be advised in patients with pre-existing conditions.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus naturally.
Evidence: Well-establishedDrinking fluids thins mucus.
Evidence: Well-establishedTechniques to help clear mucus.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines. However, if you have a respiratory infection, consult your doctor about timing of vaccinations.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines. Keep enough supply for your trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start noticing some relief within 30-60 minutes, but significant improvement in mucus clearance may take 1-2 days.
A: Inform your doctor about all medicines you take. Avoid cough suppressants and separate from antibiotics by 2 hours.
A: It is not recommended for children under 12 years without a doctor's advice.
🤔 Common Patient Concerns
🔄 Substitutes for nacfil ab tablet
View AllAlternative brands with exact same active ingredient:
-
mucorin-a 300mg/30mg tabletRhine Biogenics Pvt Ltd ₹49.00 16.1% COSTLIER
-
ambiac n 300mg/30mg tabletEsma Formulations ₹55.00 30.4% COSTLIER
-
comelt a 300mg/30mg tabletJabs Biotech Pvt Ltd ₹75.00 77.8% COSTLIER
-
kaznix a 300mg/30mg tabletSakshit Healthcare ₹87.19 106.7% COSTLIER
-
mewkus-a 300mg/30mg tabletEclipser Pharmaceuticals ₹94.00 122.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: This medicine is only for wet cough with thick mucus. It is not effective for dry cough or cough due to allergies. - Myth: It is safe to take this medicine for a long time without doctor's advice.
Fact: This medicine should not be used for more than 14 days without consulting a doctor. - Myth: This medicine can be taken with cough syrups.
Fact: Cough suppressants may reduce the effectiveness of this medicine. Consult your doctor before combining.
🔄 Alternative Options
Generic Alternatives
- Acetylcysteine + Ambroxol combination generics available.
Brand Alternatives
- Not established from the available information.