ambcet 5 mg/60 mg tablet - Cetirizine (5mg) + Ambroxol (60mg) medicine

Ambcet 5 mg/60 mg Tablet - Uses, Price, Side Effects

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🏭 Fourrts India Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is ambcet 5 mg/60 mg tablet used for?

Ambcet 5 mg/60 mg Tablet is a combination medicine used to treat respiratory allergies and cough. Cetirizine is an antihistamine that blocks histamine to relieve allergy symptoms like sneezing and runny nose. Ambroxol is a mucolytic that thins mucus, making it easier to cough up. It helps in conditions like allergic rhinitis and productive cough.

  • Generic Name: Cetirizine + Ambroxol
  • Manufacturer: Fourrts India Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 ambcet 5 mg/60 mg tablet Uses & Benefits

Allergic rhinitis, cough with thick mucus, upper respiratory tract infections

Off-label uses: Chronic urticaria, COPD exacerbations

📋 Drug Information

Generic Name(s)Cetirizine + Ambroxol
Brand NameAmcold
ManufacturerFourrts India Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Mucolytic
Route of AdministrationOral
StorageStore at 25°C (77°F); protect from light and moisture
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCetirizine: Well absorbed orally; Ambroxol: Rapidly absorbed from GI tract
DistributionCetirizine: Vd 0.5 L/kg; Ambroxol: Widely distributed, crosses placenta
Protein BindingCetirizine: 93%; Ambroxol: 90%
MetabolismCetirizine: Minimal hepatic metabolism; Ambroxol: Hepatic via glucuronidation
Half-LifeCetirizine: 8-11 hours; Ambroxol: 7-12 hours
ExcretionCetirizine: Renal (60% unchanged); Ambroxol: Renal (90% as metabolites)
BioavailabilityCetirizine: ~70%; Ambroxol: ~70-80%
Onset of ActionCetirizine: 1 hour; Ambroxol: 30 minutes
Peak Plasma TimeCetirizine: 1-2 hours; Ambroxol: 1-3 hours
Duration of ActionCetirizine: 24 hours; Ambroxol: 6-12 hours

How It Works

Cetirizine: Selective H1 receptor antagonist; Ambroxol: Increases airway secretion and reduces mucus viscosity

Mechanism Steps

1Cetirizine blocks H1 receptors, preventing histamine-mediated allergic responses
2Ambroxol stimulates serous bronchial glands, increasing fluid secretion
3Ambroxol depolymerizes mucopolysaccharides, reducing mucus viscosity
4Combined effect: reduced allergy symptoms and easier expectoration

💡 How to Take ambcet 5 mg/60 mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of ambcet 5 mg/60 mg tablet

✅ Common Side Effects

Drowsiness
Dry mouth
Fatigue
Nausea

🚨 Serious Side Effects

Severe allergic reactions
Hepatotoxicity (rare)
Arrhythmias (rare)

⚠️ Rare Side Effects

Thrombocytopenia
Stevens-Johnson syndrome
Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Alcohol Moderate Increased drowsiness and dizziness
MAOIs Major Increased risk of hypertensive crisis
CNS Depressants Moderate Enhanced sedative effect

🚨 Major Interactions

  • CNS depressants
  • Alcohol
  • MAOIs

⚡ Moderate Interactions

  • Anticholinergics
  • CYP3A4 inhibitors

🍷 Alcohol Interaction

Increased CNS depression

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to any component, severe renal impairment (CrCl

🤱 Lactation Safety

Cetirizine excreted in milk; Ambroxol likely safe

💊 Overdose Management

Symptomatic and supportive; gastric lavage if recent

⏰ Missed Dose

Take as soon as remembered; skip if almost time for next dose

🔄 Substitutes for ambcet 5 mg/60 mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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