mucorin-a 300mg/30mg tablet - Acetylcysteine (300mg) + Ambroxol (30mg) medicine

Ambiac N 300mg/30mg Tablet: Complete Medicine Guide

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🏭 Rhine Biogenics Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for mucolytic effects in respiratory conditions.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or severe wheezing
  • Swelling of face, lips, or throat
  • Severe skin rash with blisters or peeling
  • Blood in vomit or black, tarry stools
  • Chest pain or palpitations
  • High fever with chills
  • Confusion or extreme drowsiness

If experiencing severe symptoms, call emergency services immediately.

What is mucorin-a 300mg/30mg tablet used for?

This medicine is a combination of acetylcysteine and ambroxol, used to treat thick mucus in respiratory conditions like bronchitis and COPD. It works by thinning mucus and making it easier to cough out. It is usually taken 2-3 times daily as prescribed.

  • Generic Name: Acetylcysteine (300mg) + Ambroxol (30mg)
  • Manufacturer: Rhine Biogenics Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 mucorin-a 300mg/30mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एसिटाइलसिस्टीन और एम्ब्रोक्सोल का संयोजन है, जिसका उपयोग ब्रोंकाइटिस, सीओपीडी और अन्य श्वसन रोगों में गाढ़े बलगम को पतला करने और खांसी के माध्यम से बाहर निकालने में मदद करने के लिए किया जाता है। यह बलगम को पतला करती है और सांस लेने में आसानी प्रदान करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट खराब, दस्त, और सीने में जलन शामिल हैं। कभी-कभी एलर्जी, चकत्ते, सांस लेने में कठिनाई, या गंभीर त्वचा प्रतिक्रियाएं हो सकती हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ या बिना भोजन के ले सकते हैं, लेकिन पेट की परेशानी से बचने के लिए भोजन के साथ लेना बेहतर है। अस्थमा के रोगी सावधानी बरतें और अपना इनहेलर पास रखें। 14 दिनों से अधिक इसका उपयोग बिना डॉक्टर की सलाह के न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से परामर्श करें। शराब का सेवन न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 mucorin-a 300mg/30mg tablet Uses & Benefits

[{"condition":"Acute bronchitis","description":"Helps loosen thick mucus in the airways, making it easier to cough out and relieving chest congestion.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Used to manage chronic mucus hypersecretion and reduce exacerbations in chronic bronchitis patients.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"May help in thinning mucus and improving mucus clearance in COPD patients with thick secretions.","evidence":"Moderate"},{"condition":"Bronchiectasis","description":"Used as a mucolytic to help clear excessive mucus in bronchiectasis.","evidence":"Limited"},{"condition":"Cystic fibrosis","description":"Acetylcysteine is used as a mucolytic in cystic fibrosis, but the combination with ambroxol is not standard.","evidence":"Limited"}]

Off-label uses: [{"condition":"Prevention of contrast-induced nephropathy","description":"Acetylcysteine has been studied for preventing kidney damage from contrast dyes, but evidence is mixed and not for this combination.","evidence":"Limited"},{"condition":"Acetaminophen overdose","description":"Acetylcysteine is the antidote for acetaminophen poisoning, but this combination tablet is not used for that purpose.","evidence":"Well-established for acetylcysteine alone"}]

Primary treatment for: Respiratory conditions with thick mucus (e.g., bronchitis, COPD)

Also treats: Bronchiectasis, Cystic fibrosis, Sinusitis

📋 Drug Information

Generic Name(s)Acetylcysteine (300mg) + Ambroxol (30mg)
Brand Namemucorin-a 300mg/30mg tablet
ManufacturerRhine Biogenics Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day to help thin mucus.
3
Avoid alcohol while taking this medicine as it may increase stomach irritation.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 14 days.
6
If you have asthma, keep your rescue inhaler handy and report any increased wheezing.
7
Separate this medicine from antibiotics by at least 2 hours to avoid absorption issues.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Thick mucus
This medicine is commonly prescribed for this.
Likely Use
❌
Dry cough
This medicine is not for dry cough.
Not Primary
✅
Chest congestion
This medicine helps clear chest congestion.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAcetylcysteine is rapidly absorbed from the gastrointestinal tract after oral administration, but undergoes first-pass metabolism. Ambroxol is also well absorbed orally. Bioavailability of acetylcysteine is low (about 10%) due to first-pass effect, while ambroxol bioavailability is approximately 70-80%.
DistributionAcetylcysteine distributes widely into body tissues and fluids, including lung tissue. Ambroxol also distributes extensively, with high concentrations in lung tissue, bronchial secretions, and plasma. Both cross the placenta and are excreted in breast milk.
Protein BindingAcetylcysteine is about 50% bound to plasma proteins. Ambroxol is approximately 90% bound to plasma proteins.
MetabolismAcetylcysteine is metabolized in the liver to cysteine, diacetylcysteine, and other metabolites. Ambroxol is metabolized in the liver by cytochrome P450 enzymes, primarily CYP3A4, to dibromanthranilic acid and other metabolites.
Half-LifeAcetylcysteine has an elimination half-life of about 2-6 hours. Ambroxol has a half-life of approximately 7-12 hours.
ExcretionAcetylcysteine is excreted mainly in urine as metabolites. Ambroxol is excreted primarily in urine as metabolites and unchanged drug.
BioavailabilityAcetylcysteine oral bioavailability is about 10% due to first-pass metabolism. Ambroxol oral bioavailability is approximately 70-80%.
Onset of ActionMucolytic effects typically begin within 30-60 minutes after oral administration, but noticeable relief may take 1-2 days.
Peak Plasma TimeAcetylcysteine reaches peak plasma levels in about 1-2 hours. Ambroxol reaches peak plasma levels in about 1-3 hours.
Duration of ActionThe mucolytic effect lasts for about 6-8 hours, requiring multiple daily doses.

How It Works

This medicine combines two mucoactive agents. Acetylcysteine is a mucolytic that breaks disulfide bonds in mucoproteins, reducing mucus viscosity. Ambroxol is a mucolytic and expectorant that increases serous bronchial secretion, reduces mucus viscosity, and stimulates surfactant production. Together, they enhance mucus clearance and ease breathing.

Mechanism Steps

1
Acetylcysteine breaks disulfide bonds: Acetylcysteine contains a free sulfhydryl group that reduces disulfide bonds in mucus glycoproteins, making mucus less viscous.
2
Ambroxol increases serous secretion: Ambroxol stimulates serous cells in the respiratory tract to produce more watery mucus, which dilutes thick mucus.
3
Ambroxol enhances surfactant production: Ambroxol increases surfactant synthesis in type II pneumocytes, which helps keep airways open and improves mucus transport.
4
Improved mucociliary clearance: The combined actions lead to thinner mucus that is easier for cilia to move and for the patient to cough out.

💡 How to Take mucorin-a 300mg/30mg tablet

Strength: Tablet containing acetylcysteine 300 mg and ambroxol 30 mg.

1Swallow the tablet whole with a glass of water.
2Take with or without food, but with food if it upsets your stomach.
3Do not crush, chew, or break the tablet.
4Take at evenly spaced intervals as prescribed.
5Drink plenty of fluids while taking this medicine.
6Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet (acetylcysteine 300 mg + ambroxol 30 mg) two to three times daily, or as prescribed by your doctor. The dose may be adjusted based on your condition and response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustment is required for elderly patients, but caution is advised due to potential reduced liver and kidney function. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with severe kidney impairment. Dose adjustment may be necessary. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with severe liver impairment. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 3 tablets (acetylcysteine 900 mg + ambroxol 90 mg) per day, unless otherwise prescribed by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Water
Drink plenty of fluids
Helps thin mucus.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of mucorin-a 300mg/30mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated. If vomiting is severe or persistent, contact your doctor.
Stomach upset (Common (5-10%))
Take with meals. Avoid spicy foods. Consult doctor if it continues.
Diarrhea (Uncommon (1-5%))
Drink plenty of fluids. If diarrhea is severe or bloody, seek medical advice.
Heartburn (Uncommon (1-5%))
Take with food. Avoid lying down immediately after taking the medicine.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face or throat, or difficulty breathing.
Bronchospasm (Rare (<0.1%))
If you have asthma and experience increased wheezing or difficulty breathing, use your rescue inhaler and seek medical help immediately.
Severe skin reactions (Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop the medicine and seek immediate medical attention if you develop a rash with blisters, peeling skin, or sores in the mouth.
Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black, tarry stools or vomit blood.

⚠️ Rare Side Effects

Headache
Usually resolves on its own. If severe or persistent, consult your doctor.
Drowsiness
Avoid driving or operating machinery if you feel drowsy.
Rash
Stop the medicine and consult your doctor if rash develops.
Mouth irritation
Rinse mouth after taking the tablet. Consult doctor if it persists.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Nitroglycerin Major
Codeine Major
Amoxicillin Moderate
Dextromethorphan Moderate
Activated charcoal Minor

🚨 Major Interactions

  • Nitroglycerin
  • Cough suppressants (e.g., codeine)

⚡ Moderate Interactions

  • Antibiotics (e.g., amoxicillin, tetracycline)
  • Antitussives (e.g., dextromethorphan)

🍷 Alcohol Interaction

Alcohol may increase the risk of stomach irritation and gastrointestinal bleeding. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to acetylcysteine, ambroxol, or any component of the formulation.","Active peptic ulcer disease.","Severe liver disease.","Severe kidney disease.","Children under 12 years (unless prescribed by a doctor)."]

⚠️ Warnings & Precautions

["Use with caution in patients with asthma; may cause bronchospasm.","Avoid use in patients with active peptic ulcer.","Use with caution in patients with severe liver or kidney impairment.","Do not use for more than 14 days without medical advice.","May cause drowsiness; avoid driving if affected.","Do not use cough suppressants concurrently.","Separate from antibiotics by at least 2 hours."]

🤱 Lactation Safety

Acetylcysteine and ambroxol are excreted in breast milk. It is not known if they are safe for the breastfed infant. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause nausea, vomiting, and diarrhea. Seek immediate medical attention. Treatment is symptomatic and supportive. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. Swallow the tablet whole with a glass of water. It can be taken with or without food, but taking it with food may reduce stomach upset. If you have asthma, use this medicine with caution and keep your rescue inhaler handy. Do not use this medicine for more than 14 days without consulting your doctor. Avoid alcohol while taking this medicine as it may increase stomach irritation. If you are pregnant or breastfeeding, consult your doctor before taking this medicine. Do not share this medicine with others, even if they have similar symptoms. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to side effects. Use with caution and monitor for stomach upset and drowsiness. Dose adjustment may be needed based on liver and kidney function.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy or if you become pregnant while taking this medicine. The safety of this combination during pregnancy is not well established.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with certain medications used during surgery.

🦷 Dental Procedures

No specific precautions for dental procedures. However, inform your dentist about all medicines you take.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated by drinking plenty of water.
🥗
Use a humidifier to keep airways moist.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Practice deep breathing exercises to help clear mucus.
🧘
Get adequate rest to support recovery.

🏋️ Exercise Considerations

Avoid strenuous exercise if you have difficulty breathing. Gentle activities like walking may help. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Drink warm fluids like herbal tea or soup.
Include fruits rich in vitamin C.
Avoid dairy products if they thicken mucus.
Reduce intake of processed foods.
Eat a balanced diet to support immunity.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness in some people. Avoid driving or operating heavy machinery if you feel drowsy. It does not usually affect your ability to work, but take precautions.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if you experience severe side effects, allergic reactions, or if your symptoms do not improve within 14 days. Do not stop abruptly if you have been on long-term therapy without medical advice.

📅 Long-Term Use Effects

Long-term use beyond 14 days is not recommended without medical supervision. Prolonged use may lead to gastrointestinal discomfort. Regular monitoring of liver and kidney function may be advised in patients with pre-existing conditions.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus naturally.

Evidence: Well-established
Hydration

Drinking fluids thins mucus.

Evidence: Well-established
Chest physiotherapy

Techniques to help clear mucus.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines. However, if you have a respiratory infection, consult your doctor about timing of vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines. Keep enough supply for your trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old man with chronic bronchitis
He had persistent cough with thick mucus for weeks. His doctor prescribed this medicine. After 3 days, he noticed the mucus was thinner and easier to cough out. He took it with food to avoid stomach upset and drank plenty of water.
💡 Lesson: Taking the medicine with food and staying hydrated improves tolerability and effectiveness.
👤 A 60-year-old woman with COPD
She experienced frequent chest congestion. Her doctor added this medicine to her regimen. She found that her breathing improved and she could clear her chest more easily. She was advised not to use cough suppressants and to continue her inhalers.
💡 Lesson: This medicine works best when combined with other treatments and avoiding cough suppressants.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start noticing some relief within 30-60 minutes, but significant improvement in mucus clearance may take 1-2 days.

Q: Can I take it with other medicines?

A: Inform your doctor about all medicines you take. Avoid cough suppressants and separate from antibiotics by 2 hours.

Q: Is it safe for children?

A: It is not recommended for children under 12 years without a doctor's advice.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for mucorin-a 300mg/30mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: This medicine is only for wet cough with thick mucus. It is not effective for dry cough or cough due to allergies.
  • Myth: It is safe to take this medicine for a long time without doctor's advice.
    Fact: This medicine should not be used for more than 14 days without consulting a doctor.
  • Myth: This medicine can be taken with cough syrups.
    Fact: Cough suppressants may reduce the effectiveness of this medicine. Consult your doctor before combining.

🔄 Alternative Options

Generic Alternatives

  • Acetylcysteine + Ambroxol combination generics available.

Brand Alternatives

  • Not established from the available information.

📊 Comparison with Similar Medicines

[{"medicine":"Acetylcysteine + Ambroxol","composition":"Acetylcysteine 300 mg + Ambroxol 30 mg","uses":"Thick mucus in respiratory conditions","notes":"Combination mucolytic and expectorant."},{"medicine":"Acetylcysteine alone","composition":"Acetylcysteine 600 mg","uses":"Mucolytic for thick mucus","notes":"Single agent, often used in higher doses."},{"medicine":"Ambroxol alone","composition":"Ambroxol 30 mg","uses":"Mucolytic and expectorant","notes":"Single agent, also available as syrup."}]

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