Fepra 500mg Tablet Sr: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is Fepra 500mg Tablet SR used for?
This medicine is an NSAID used to relieve pain and inflammation in conditions like arthritis and musculoskeletal injuries. It works by blocking COX enzymes and is taken orally with food. It should be used under medical supervision and avoided in people with stomach ulcers, kidney disease, or heart failure.
- Generic Name: Aceclofenac (500mg)
- Manufacturer: Triton Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Fepra 500mg Tablet SR के बारे में (Hindi Summary)
उपयोग: यह दवा मुख्य रूप से दर्द और सूजन को कम करने के लिए इस्तेमाल की जाती है। यह गठिया (आर्थराइटिस), कमर दर्द, मांसपेशियों की चोट, और दांत दर्द जैसी समस्याओं में राहत देती है। यह शरीर में उन रसायनों को रोकती है जो दर्द और सूजन पैदा करते हैं। इसे डॉक्टर की सलाह के बिना लंबे समय तक नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट में जलन, मतली, अपच, और पेट दर्द शामिल हैं। कुछ लोगों को सिरदर्द या चक्कर भी आ सकते हैं। गंभीर मामलों में पेट में ब्लीडिंग, अल्सर, किडनी या लिवर की समस्या हो सकती है। अगर काला मल, खून की उल्टी, तेज पेट दर्द, या आंखों का पीलापन दिखे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को हमेशा भोजन के साथ या खाने के तुरंत बाद लें ताकि पेट में जलन न हो। दूध या पानी के साथ लेना फायदेमंद है। शराब बिल्कुल न पिएं क्योंकि इससे पेट में ब्लीडिंग का खतरा बढ़ जाता है। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें। अगर आपको किडनी, लिवर, या दिल की बीमारी है तो डॉक्टर को पहले बताएं। डॉक्टर की सलाह के बिना दवा बंद या शुरू न करें।
💊 Fepra 500mg Tablet SR Uses & Benefits
[{"condition":"Osteoarthritis","description":"This medicine reduces joint pain, stiffness, and inflammation" class="semantic-link" title="Medicines for swelling">swelling, helping patients move more comfortably.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"It helps control inflammatory joint pain and improves morning stiffness when used as part of a treatment plan.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"This medicine relieves back and sacroiliac pain and stiffness associated with this inflammatory spine condition.","evidence":"Well-established"},{"condition":"Acute musculoskeletal injuries","description":"It is used for short-term relief of pain and swelling after sprains, strains, and sports injuries.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Sometimes prescribed for a short period after surgery to manage inflammatory pain.","evidence":"Moderate"},{"condition":"Dental pain","description":"It can relieve pain and inflammation after dental procedures or in acute dental infections.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine headache","description":"Occasionally used off-label for acute migraine pain, but it is not a first-line treatment.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"Sometimes used off-label for menstrual cramps, though other NSAIDs are more commonly prescribed.","evidence":"Limited"}]
Primary treatment for: Inflammatory pain conditions such as osteoarthritis, rheumatoid arthritis, and musculoskeletal injuries.
Also treats: Ankylosing spondylitis, Acute gout, Post-operative pain, Dental pain
📋 Drug Information
| Generic Name(s) | Aceclofenac (500mg) |
| Brand Name | Fepra 500mg Tablet SR |
| Manufacturer | Triton Healthcare Pvt Ltd |
| Packaging / Form | strip of 10 tablet sr (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the cyclooxygenase (COX) enzymes, particularly COX-2, which are responsible for converting arachidonic acid into prostaglandins. Prostaglandins are chemical messengers that sensitize pain nerve endings and promote inflammation, swelling, and fever. By blocking COX-2, this medicine reduces the production of prostaglandins at the site of injury or inflammation, leading to less pain and swelling. It also has a modest effect on COX-1, which is why it can cause stomach irritation. The overall result is analgesic, anti-inflammatory, and antipyretic activity.
Mechanism Steps
💡 How to Take Fepra 500mg Tablet SR
Strength: Aceclofenac 500 mg sustained-release tablet for oral use.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one 500 mg tablet taken once or twice daily with food, depending on the condition being treated and the severity of symptoms. For acute pain, it may be taken twice daily for a short period. For chronic conditions like arthritis, the doctor may adjust the dose based on response and tolerability. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients above 65 years are more sensitive to the side effects of this medicine, especially stomach bleeding, kidney problems, and cardiovascular events. The lowest effective dose should be used for the shortest possible duration, and kidney function should be monitored. |
| Renal Impairment | In patients with mild to moderate kidney impairment, this medicine should be used with caution and at the lowest effective dose. It is contraindicated in severe kidney disease. Dose must be individualized by a qualified clinician based on renal function. |
| Hepatic Impairment | In patients with mild to moderate liver impairment, this medicine should be used with caution. It is contraindicated in severe liver disease. Dose must be individualized by a qualified clinician based on hepatic function. |
| Maximum Daily Dose | The maximum recommended daily dose is 200 mg per day, but the usual prescribed dose is 100 mg twice daily or 200 mg once daily. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Fepra 500mg Tablet SR
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| Aspirin | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Moderate | |
| SSRIs | Moderate | |
| Cyclosporine | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin and other anticoagulants
- Other NSAIDs (e.g., ibuprofen, naproxen, aspirin)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- Antihypertensives (ACE inhibitors, ARBs, diuretics)
- SSRIs
- Cyclosporine
- Digoxin
🍷 Alcohol Interaction
Alcohol should be strictly avoided while taking this medicine. Both alcohol and this medicine irritate the stomach lining and increase the risk of bleeding and ulcers. Alcohol can also add to dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active or history of peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe kidney disease","Severe liver disease","Known allergy to aceclofenac or other NSAIDs","Asthma triggered by aspirin or NSAIDs","Third trimester of pregnancy","Coronary artery bypass graft surgery (perioperative period)"]
⚠️ Warnings & Precautions
["Take with food to reduce stomach upset.","Avoid alcohol completely.","Do not use with other NSAIDs.","Use with caution in elderly patients.","Monitor kidney and liver function during long-term use.","Stop and seek medical help if you notice signs of bleeding.","Do not drive if you feel dizzy or drowsy.","Inform your doctor if you have heart disease, high blood pressure, or diabetes."]
🤱 Lactation Safety
This medicine may pass into breast milk in small amounts. It is generally not recommended during breastfeeding unless the benefit outweighs the risk. Consult your doctor for safer alternatives.
💊 Overdose Management
Overdose of this medicine can cause severe stomach pain, nausea, vomiting, headache, dizziness, and in serious cases, gastrointestinal bleeding, kidney failure, or liver damage. If you suspect an overdose, contact your doctor or go to the nearest emergency department immediately. Treatment is supportive and may include activated charcoal, stomach lavage, and monitoring of vital organs.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Swallow the tablet whole with a full glass of water and take it with or immediately after a meal to reduce stomach irritation. Do not crush, chew, or break the tablet unless your doctor advises otherwise. Avoid taking other pain relievers, especially other NSAIDs such as ibuprofen, naproxen, or aspirin, without consulting your doctor, because the risk of stomach bleeding and kidney problems increases. Do not drink alcohol while taking this medicine, as it can worsen stomach irritation and bleeding. If you have high blood pressure, kidney disease, liver disease, or heart disease, inform your doctor before starting this medicine. Do not use this medicine for more than the recommended duration without medical review. Keep all follow-up appointments so your doctor can monitor your response and check for any unwanted effects.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of stomach bleeding, kidney problems, and cardiovascular side effects. Use the lowest effective dose for the shortest duration and monitor kidney function regularly. Avoid combining with other NSAIDs or blood thinners.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy or are pregnant, avoid this medicine unless clearly advised by your doctor. NSAIDs may affect ovulation and are not recommended during pregnancy, especially in the third trimester. Discuss safer alternatives with your doctor.
🏥 Post-Surgery Considerations
This medicine may be used for short-term pain relief after surgery, but it should be used with caution because it can increase bleeding risk and affect kidney function. Follow your surgeon's instructions carefully.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding. Your dentist may advise you to stop it temporarily before surgery.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you can continue gentle exercises, but avoid high-impact activities that may strain your joints or cause injury. If you feel dizzy or tired, avoid strenuous exercise. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It generally does not affect your ability to work, but take breaks and stay hydrated if your job involves physical strain.
🛑 When to Stop This Medicine
Stop this medicine and consult your doctor immediately if you experience severe stomach pain, black or bloody stools, vomiting blood, yellowing of eyes or skin, decreased urine output, or signs of an allergic reaction. Do not stop long-term therapy abruptly without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, liver enzyme elevation, and cardiovascular events. Regular monitoring of kidney and liver function, blood pressure, and blood counts may be required. It should be used at the lowest effective dose for the shortest duration. Consult your doctor for periodic reviews.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedMay help reduce localized pain and swelling.
Evidence: ModerateReduces stress on weight-bearing joints and improves arthritis symptoms.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, continue your doses as prescribed, but do not take extra doses to adjust for time changes. Keep it in your hand luggage if flying. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief usually begins within 30 to 60 minutes after taking a dose, but the full anti-inflammatory effect may take a few days of regular use.
A: No, it should be taken with food or immediately after a meal to reduce the risk of stomach irritation and ulcers.
A: Long-term use should be under medical supervision with periodic monitoring of kidney and liver function. Use the lowest effective dose for the shortest duration.
A: Do not take it with other NSAIDs unless your doctor approves, as it increases the risk of bleeding and kidney problems.
🤔 Common Patient Concerns
🔄 Substitutes for Fepra 500mg Tablet SR
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food to reduce the risk of stomach irritation and ulcers. - Myth: This medicine is safe to take with other painkillers.
Fact: Combining with other NSAIDs increases the risk of bleeding and kidney problems. - Myth: This medicine can cure arthritis.
Fact: It only relieves pain and inflammation; it does not cure the underlying disease. - Myth: It is safe to take this medicine for months without monitoring.
Fact: Long-term use requires periodic monitoring of kidney and liver function.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac 500 mg Tablet SR
Brand Alternatives
- Fepra 500mg Tablet SR