amicalm 200mg tablet - Uses, Price, Side Effects & Substitutes
What is amicalm 200mg tablet used for?
Amisant 200 Tablet (Amisulpride) is used to treat NEURO CNS. It contains Amisulpride (200mg), which Selective antagonist at dopamine D2 and D3 receptors, with higher affinity for D. Always consult your doctor before use. Take as prescribed.
- Generic Name: Amisulpride
- Manufacturer: Triton Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ amicalm 200mg tablet Uses & Benefits
Schizophrenia (positive and negative symptoms); acute psychotic episodes; maintenance therapy.
Off-label uses: Bipolar depression, anxiety disorders, obsessive-compulsive disorder (limited evidence).
๐ Drug Information
| Generic Name(s) | Amisulpride |
| Brand Name | Amisant 200 Tablet |
| Manufacturer | Triton Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Atypical Antipsychotics |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30ยฐC), protected from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Selective antagonist at dopamine D2 and D3 receptors, with higher affinity for D3 receptors. It also has some antagonistic activity at serotonin 5-HT2A receptors.
Mechanism Steps
๐ก How to Take amicalm 200mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of amicalm 200mg tablet
โ Common Side Effects
- Insomnia
- Anxiety
- Agitation
- Weight gain
- Constipation
- Nausea
- Dry mouth
- Sedation
๐จ Serious Side Effects
- QT prolongation
- Torsades de pointes
- Neuroleptic malignant syndrome
- Seizures
- Tardive dyskinesia
- Prolactin elevation (galactorrhea, gynecomastia)
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Agranulocytosis
- Venous thromboembolism
- Pancreatitis
- Allergic reactions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Levodopa | Major | Antagonism of dopaminergic effects; reduced efficacy of levodopa. |
| QT-prolonging drugs | Major | Increased risk of ventricular arrhythmias. |
| CYP3A4 inhibitors | Major | Increased amisulpride plasma concentration; risk of toxicity. |
| Antihypertensives | Moderate | Additive hypotensive effect. |
| CNS depressants | Moderate | Enhanced sedation and respiratory depression. |
| Lithium | Moderate | Increased risk of neurotoxicity. |
| Antacids | Minor | Possible reduced absorption of amisulpride. |
| Cimetidine | Minor | Slight increase in amisulpride levels. |
๐จ Major Interactions
- Levodopa
- Dopamine agonists
- QT-prolonging drugs
- CYP3A4 inhibitors
โก Moderate Interactions
- Antihypertensives
- CNS depressants
- Lithium
โน๏ธ Minor Interactions
- Antacids
- Cimetidine
๐ฝ๏ธ Food Interactions
Food may delay absorption but does not significantly affect bioavailability.
๐ท Alcohol Interaction
Alcohol may enhance CNS depressant effects; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to amisulpride; concomitant use with prolactin-dependent tumors; known QT prolongation; severe renal impairment (CrCl <10 mL/min); pheochromocytoma.
๐ Monitoring Parameters
ECG (QT interval), blood pressure, liver function tests, renal function, prolactin levels, extrapyramidal symptoms.
๐คฑ Lactation Safety
Not recommended; amisulpride is excreted in breast milk and may cause adverse effects in the infant.
๐ Overdose Management
Supportive care; ECG monitoring; activated charcoal if recent ingestion; no specific antidote; treat arrhythmias as needed.
โฐ Missed Dose
Take as soon as remembered unless close to next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for amicalm 200mg tablet
View AllAlternative brands with exact same active ingredient (Amisulpride (200mg)):
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absull 200 tablet srAbseil Pharmaceticals Pvt Ltd โน115.00 14.9% CHEAPER
-
stayhappi amisulpride 200mg tabletSarvagunaushdhi Pvt Ltd โน135.00 0.2% CHEAPER
-
cenride 200 mg tabletUSV Ltd โน138.75 2.6% COSTLIER
-
trikosul 200mg tabletTriko Pharmaceuticals โน142.86 5.7% COSTLIER
-
atypride 200mg tabletIkon Pharmachem Pvt Ltd โน143.28 6% COSTLIER
-
eripride 200mg tabletEridanus Healthcare โน148.00 9.5% COSTLIER
-
zonapride 200mg tabletMankind Pharma Ltd โน148.00 9.5% COSTLIER
-
cyam 200mg tabletCybele Bio sciences Pvt Ltd โน150.00 10.9% COSTLIER
-
psyride 200 tabletPsycormedies โน155.40 14.9% COSTLIER
-
amiselect 200mg tabletOrchid Chemicals & Pharmaceuticals Ltd โน157.00 16.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.