axil 500mg tablet - Aceclofenac (500mg) medicine

Axil 500mg Tablet: Complete Medicine Guide

No reviews yet
🏭 Katg Therapeutics Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 27, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. However, NSAIDs like this medicine are generally avoided during pregnancy, especially in the third trimester, due to risk of premature closure of ductus arteriosus and other complications. Consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 27, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is axil 500mg tablet used for?

This medicine is an NSAID used to treat pain and inflammation in conditions like arthritis. It works by blocking COX-2 enzymes. Take it with food to avoid stomach upset. Do not use without a prescription.

  • Generic Name: Aceclofenac
  • Manufacturer: Katg Therapeutics Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 axil 500mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा मुख्य रूप से गठिया (ऑस्टियोआर्थराइटिस, रूमेटॉइड आर्थराइटिस), कमर दर्द, जोड़ों के दर्द और सूजन के इलाज के लिए इस्तेमाल की जाती है। यह दर्द और सूजन को कम करने में मदद करती है। इसे डॉक्टर की सलाह के बिना न लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट दर्द, जी मिचलाना, अपच, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या और हृदय संबंधी जोखिम शामिल हो सकते हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। डॉक्टर की सलाह के बिना 7 दिन से ज्यादा इसका इस्तेमाल न करें। अगर आपको हृदय, गुर्दे या लीवर की समस्या है तो डॉक्टर को बताएं।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 axil 500mg tablet Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate back pain and stiffness associated with ankylosing spondylitis.","evidence":"Well-established"},{"condition":"Acute musculoskeletal injuries","description":"Provides short-term relief for sprains, strains, and other soft tissue injuries.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for management of mild to moderate post-surgical pain and inflammation.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, though other NSAIDs are more commonly used.","evidence":"Limited"}]

Primary treatment for: Osteoarthritis

Also treats: Rheumatoid arthritis, Ankylosing spondylitis, Acute musculoskeletal injuries, Post-operative pain

📋 Drug Information

Generic Name(s)Aceclofenac
Brand NameAceclo Tablet
ManufacturerKatg Therapeutics Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to minimize stomach irritation.
2
Do not exceed the prescribed dose; taking more does not provide better pain relief and increases side effects.
3
Avoid alcohol completely while on this medicine to prevent gastrointestinal bleeding.
4
If you have a history of heart, kidney, or liver disease, inform your doctor before starting this medicine.
5
Do not use this medicine for more than 7 days without consulting your doctor.
6
Report any signs of bleeding, such as black stools or blood in vomit, immediately.
7
Stay well hydrated throughout the day to support kidney function.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Acute injury swelling
This medicine can help reduce swelling and pain.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed from the gastrointestinal tract after oral administration. Food may delay absorption but does not significantly affect the extent of absorption.
DistributionThis medicine is highly bound to plasma proteins and distributes well into synovial fluid, which is beneficial for joint conditions.
Protein BindingGreater than 99% bound to plasma proteins, primarily albumin.
MetabolismThis medicine is extensively metabolized in the liver, primarily by cytochrome P450 enzymes, including CYP2C9.
Half-LifeThe elimination half-life of this medicine is approximately 4-6 hours.
ExcretionThis medicine and its metabolites are excreted mainly through the urine and to a lesser extent in feces.
BioavailabilityThe oral bioavailability of this medicine is approximately 80-90%.
Onset of ActionPain relief typically begins within 30-60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations are reached approximately 1.5-3 hours after oral administration.
Duration of ActionThe analgesic and anti-inflammatory effects last for about 12-24 hours, allowing for once or twice daily dosing.

How It Works

This medicine works by inhibiting the cyclooxygenase (COX) enzymes, primarily COX-2, which are responsible for the production of prostaglandins. Prostaglandins are chemicals that mediate pain, inflammation, and fever. By blocking COX-2, this medicine reduces the synthesis of prostaglandins, thereby decreasing pain and swelling. It has a relatively selective action on COX-2 compared to COX-1, which may result in fewer gastrointestinal side effects than non-selective NSAIDs, but the risk is still present.

Mechanism Steps

1
Absorption and distribution: After oral intake, this medicine is absorbed in the gastrointestinal tract and distributed to target tissues.
2
COX-2 inhibition: This medicine selectively binds to and inhibits the COX-2 enzyme, blocking the conversion of arachidonic acid to prostaglandins.
3
Reduced prostaglandin synthesis: The inhibition of COX-2 leads to decreased production of prostaglandins, which are key mediators of pain and inflammation.
4
Analgesic and anti-inflammatory effects: The reduced prostaglandin levels result in less pain, swelling, and joint stiffness.

💡 How to Take axil 500mg tablet

Strength: Aceclofenac 500mg tablet

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3Take with food or milk to reduce stomach upset.
4Do not crush, chew, or break the tablet unless instructed.
5Take at the same time each day to maintain consistent levels.
6Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 100mg twice daily or 200mg once daily, taken orally with food. However, the dose may vary depending on the condition being treated and the patient's response. For acute pain, a starting dose of 100mg twice daily is common. The maximum recommended daily dose is 200mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney impairment. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with mild to moderate kidney impairment, dose adjustment may not be necessary, but caution is advised. In severe kidney impairment, this medicine is contraindicated. Dose must be individualized by a qualified clinician based on renal function.
Hepatic ImpairmentIn patients with mild to moderate liver impairment, dose adjustment may be necessary. In severe liver impairment, this medicine is contraindicated. Dose must be individualized by a qualified clinician based on hepatic function.
Maximum Daily Dose200mg per day

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of axil 500mg tablet

✅ Common Side Effects

Stomach pain (Common (5-10%))
Take with food or milk. If persistent, consult your doctor.
Nausea (Common (5-10%))
Take with food. Avoid fatty meals. Consult doctor if severe.
Indigestion (Common (5-10%))
Take with food. Avoid alcohol. Consult doctor if persistent.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if severe or persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Peptic ulcer (Rare (<0.1%))
Report persistent stomach pain or heartburn to your doctor immediately.
Kidney impairment (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor.
Cardiovascular events (Rare (<0.1%))
Seek immediate medical attention if you experience chest pain, shortness of breath, or weakness.

⚠️ Rare Side Effects

Severe allergic reaction (anaphylaxis)
Call emergency services immediately if you experience swelling of face, lips, throat, or difficulty breathing.
Stevens-Johnson syndrome
Seek immediate medical attention if you develop a rash with blisters, peeling skin, or sores in mouth.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Aspirin Major
Other NSAIDs Major
Corticosteroids Major
Lithium Major
Diuretics Moderate
ACE inhibitors Moderate
Methotrexate Moderate
Cyclosporine Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Aspirin
  • Other NSAIDs
  • Corticosteroids
  • Lithium

⚡ Moderate Interactions

  • Diuretics
  • ACE inhibitors
  • Methotrexate
  • Cyclosporine

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding and may worsen stomach irritation.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to Aceclofenac or other NSAIDs","History of asthma, urticaria, or allergic reaction to aspirin or NSAIDs","Active or history of peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe kidney impairment","Severe liver impairment","Third trimester of pregnancy","Coronary artery bypass graft surgery (peri-operative period)"]

⚠️ Warnings & Precautions

["Take with food to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not use for more than 7 days without medical advice.","Use with caution in elderly patients due to increased risk of side effects.","Monitor kidney and liver function during long-term use.","May increase risk of cardiovascular events; use with caution in patients with heart disease.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not take other NSAIDs concurrently."]

🤱 Lactation Safety

This medicine may pass into breast milk. It is not recommended during breastfeeding unless clearly needed. Consult your doctor to weigh benefits and risks.

💊 Overdose Management

Overdose of this medicine may cause nausea, vomiting, stomach pain, dizziness, and in severe cases, gastrointestinal bleeding, kidney failure, or liver damage. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Take this medicine with food or milk to reduce stomach upset. Do not exceed the prescribed dose. Avoid alcohol while taking this medicine as it increases the risk of stomach bleeding. Do not use this medicine for more than 7 days without consulting your doctor. If you have a history of heart disease, high blood pressure, kidney or liver problems, or stomach ulcers, inform your doctor before taking this medicine. Do not take other NSAIDs or pain relievers concurrently without medical advice. Regular monitoring of kidney and liver function may be needed during long-term use. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration and monitor closely.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy, especially in the third trimester. If you are planning pregnancy, consult your doctor to discuss alternative pain management options.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain, but it can increase the risk of bleeding. Inform your surgeon if you are taking this medicine before any surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may increase the risk of bleeding.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.
🌞
Avoid smoking and limit alcohol.

🏋️ Exercise Considerations

Avoid high-impact exercises that may worsen joint pain. Consult your doctor or physiotherapist for an exercise plan suitable for your condition.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated
Eat plenty of fruits and vegetables

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food.

🛑 When to Stop This Medicine

Do not stop this medicine abruptly without consulting your doctor, especially if you have been taking it for a long time. Your doctor may advise tapering the dose or switching to another medicine.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of kidney and liver function is recommended. Use the lowest effective dose for the shortest duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Hot/cold therapy

May help reduce joint stiffness and pain.

Evidence: Moderate
Weight management

Reduces stress on weight-bearing joints.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, consult your doctor before any vaccination if you are on long-term NSAID therapy.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old retired teacher with rheumatoid arthritis
Was prescribed this medicine for joint pain and swelling. After 1 month, experienced relief in hand and wrist joints. Regular monitoring of kidney function was done as advised.
💡 Lesson: Long-term use requires regular monitoring of kidney and liver function to prevent complications.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30-60 minutes after taking it with food.

Q: Can I take it on an empty stomach?

A: No, it should be taken with food or milk to reduce the risk of stomach upset.

Q: Is it safe to take with other painkillers?

A: Do not take other NSAIDs or painkillers without consulting your doctor, as it may increase the risk of side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for axil 500mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure arthritis.
    Fact: This medicine only relieves symptoms; it does not cure arthritis.
  • Myth: It is safe to take this medicine without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under medical supervision.
  • Myth: This medicine can be taken on an empty stomach.
    Fact: It should be taken with food to reduce stomach upset.

🔄 Alternative Options

Generic Alternatives

  • Aceclofenac 100mg tablet
  • Aceclofenac 200mg tablet

Brand Alternatives

  • Aceclo
  • Zerodol
  • Hifenac

📊 Comparison with Similar Medicines

[{"medicine":"Aceclofenac","class":"NSAID","half_life":"4-6 hours","common_use":"Arthritis pain"},{"medicine":"Diclofenac","class":"NSAID","half_life":"1-2 hours","common_use":"Arthritis pain"},{"medicine":"Ibuprofen","class":"NSAID","half_life":"2 hours","common_use":"Pain and fever"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory