corgest 100mg injection

4.6 (16 reviews)

Progesterone (Natural Micronized) (100mg)

🏭 Ravenbhel Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is corgest 100mg injection used for?

Aqsusten 25 Solution for Injection (Progesterone (Natural Micronized)) is used to treat GYNAECOLOGICAL. It contains Progesterone (Natural Micronized) (100mg), which Progesterone binds to progesterone receptors, modulating gene expression and exe. Always consult your doctor before use. Take as prescribed.

Generic Name: Progesterone (Natural Micronized)
Manufacturer: Ravenbhel Pharmaceuticals Pvt Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 corgest 100mg injection Uses & Benefits

Luteal phase support in assisted reproductive technology, treatment of luteal phase deficiency, secondary amenorrhea, dysfunctional uterine bleeding.

Off-label uses: Prevention of preterm labor, treatment of endometriosis, menopausal hormone therapy.

📋 Drug Information

Generic Name(s)	Progesterone (Natural Micronized)
Brand Name	Aqsusten 25 Solution for Injection
Manufacturer	Ravenbhel Pharmaceuticals Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	GYNAECOLOGICAL
Action Class	Natural Progesterone
Route of Administration	Intramuscular injection.
Storage	Store at 20-25°C (68-77°F); protect from light.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after intramuscular injection; peak plasma concentrations achieved within 2-6 hours.

DistributionDistributed widely; crosses placenta and enters breast milk; highly bound to plasma proteins.

Protein Binding96-99% bound to albumin and corticosteroid-binding globulin.

MetabolismPrimarily hepatic via reduction and conjugation; major metabolites include pregnanediol and pregnanolone.

Half-LifeApproximately 16-20 hours.

ExcretionPrimarily renal as metabolites; small amount in feces.

Bioavailability100% after intramuscular injection.

Onset of ActionRapid; within hours.

Peak Plasma Time2-6 hours post-injection.

Duration of ActionApproximately 24 hours.

How It Works

Progesterone binds to progesterone receptors, modulating gene expression and exerting progestational effects on the endometrium, reducing uterine contractility, and supporting pregnancy.

Mechanism Steps

1Progesterone binds to progesterone receptor (PR) in target cells.

2Receptor-ligand complex translocates to nucleus.

3Complex binds to progesterone response elements (PRE) on DNA.

💡 How to Take corgest 100mg injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of corgest 100mg injection

✅ Common Side Effects

Injection site pain
dizziness
headache
nausea
breast tenderness
bloating

🚨 Serious Side Effects

Thromboembolism
stroke
myocardial infarction
pulmonary embolism
hepatic dysfunction

⚠️ Rare Side Effects

Cholestatic jaundice
anaphylaxis
depression
visual disturbances

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Rifampin	Major	Reduced progesterone efficacy due to increased metabolism.
Ketoconazole	Major	Increased progesterone levels and risk of side effects.
Warfarin	Moderate	Possible altered anticoagulant effect.
Grapefruit juice	Minor	May slightly increase progesterone levels.

🚨 Major Interactions

CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin)
CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

⚡ Moderate Interactions

Warfarin
Corticosteroids
Antidiabetic agents

ℹ️ Minor Interactions

Grapefruit juice
St. John's Wort

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

May enhance sedative effects; caution advised.

🛡️ Safety & Warnings

🚫 Contraindications

Known hypersensitivity, undiagnosed vaginal bleeding, active thromboembolic disorders, severe hepatic dysfunction, known or suspected pregnancy (except for specific indications).

📊 Monitoring Parameters

Progesterone levels, pregnancy test, liver function tests, signs of thromboembolism.

🤱 Lactation Safety

Excreted in breast milk; use with caution, especially in high doses.

💊 Overdose Management

No specific antidote; supportive care; symptoms may include drowsiness, dizziness, nausea.

⏰ Missed Dose

Administer as soon as remembered; if close to next dose, skip missed dose and resume regular schedule; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.