AF Kit Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction (rash, swelling, difficulty breathing)
- Seizures or convulsions
- Yellowing of skin or eyes (jaundice)
- Severe abdominal pain or persistent vomiting
- Irregular heartbeat or palpitations
- Numbness or tingling in hands or feet
- Blood in stool or vomit
If experiencing severe symptoms, call emergency services immediately.
What is af kit tablet used for?
This medicine is a combination of Azithromycin and Ornidazole used to treat mixed bacterial and protozoal infections. It works by stopping bacterial growth and killing protozoa. It is taken orally once daily for 3-7 days as prescribed.
- Generic Name: Azithromycin + Ornidazole
- Manufacturer: Systopic Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 af kit tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एज़िथ्रोमाइसिन और ओर्निडाज़ोल का संयोजन है, जिसका उपयोग बैक्टीरिया और प्रोटोज़ोआ से होने वाले मिश्रित संक्रमणों के इलाज के लिए किया जाता है। यह बैक्टीरियल वेजिनोसिस, पेल्विक इन्फ्लेमेटरी डिजीज, और कुछ गैस्ट्रोइंटेस्टाइनल संक्रमणों में प्रभावी है। यह दवा केवल डॉक्टर के पर्चे पर ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, मुँह में धातु जैसा स्वाद, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, दौरे, लीवर की समस्या और त्वचा पर गंभीर प्रतिक्रियाएँ हो सकती हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। दवा लेते समय और आखिरी खुराक के 48 घंटे बाद तक शराब न पिएँ। यदि आपको लीवर या किडनी की समस्या, दौरे, या दिल की बीमारी है तो डॉक्टर को बताएं। दवा का पूरा कोर्स पूरा करें। चक्कर आने पर वाहन न चलाएँ।
💊 af kit tablet Uses & Benefits
[{"condition":"Bacterial vaginosis","description":"This medicine is used to treat bacterial vaginosis, a common vaginal infection caused by an overgrowth of bacteria, often involving both aerobic and anaerobic organisms.","evidence":"Well-established"},{"condition":"Pelvic inflammatory disease","description":"It is prescribed for pelvic inflammatory disease, a polymicrobial infection of the upper female reproductive tract, to cover both bacterial and protozoal pathogens.","evidence":"Well-established"},{"condition":"Gastrointestinal infections","description":"This medicine may be used for certain gastrointestinal infections caused by susceptible bacteria and protozoa, such as amoebiasis and giardiasis, when combined therapy is needed.","evidence":"Moderate"},{"condition":"Mixed aerobic-anaerobic infections","description":"It is used in mixed infections where both aerobic bacteria and anaerobic bacteria or protozoa are suspected, due to its broad-spectrum coverage.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Dental infections","description":"Sometimes prescribed off-label for dental abscesses or periodontal infections when a combination of antibiotics is deemed necessary.","evidence":"Limited"},{"condition":"Skin and soft tissue infections","description":"May be used off-label for complicated skin infections where mixed organisms are involved, though not a first-line choice.","evidence":"Limited"}]
Primary treatment for: Mixed bacterial and protozoal infections
Also treats: Bacterial vaginosis, Pelvic inflammatory disease, Amoebiasis, Giardiasis
📋 Drug Information
| Generic Name(s) | Azithromycin + Ornidazole |
| Brand Name | AF Kit Tablet |
| Manufacturer | Systopic Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Antibiotic + Antiprotozoal |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep in the original packaging. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Azithromycin, a macrolide antibiotic, binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and thereby stopping bacterial growth. Ornidazole, a nitroimidazole derivative, enters microbial cells and is reduced to reactive intermediates that damage DNA, leading to cell death. Together, they provide broad-spectrum activity against a range of bacteria and protozoa.
Mechanism Steps
💡 How to Take af kit tablet
Strength: Azithromycin 1000 mg + Ornidazole 750 mg immediate-release tablets.
Dosage Information
| Adult Dosage | The usual adult dose is one kit (Azithromycin 1000 mg + Ornidazole 750 mg) taken orally once daily for 3 to 7 days, depending on the indication. The exact dose and duration must be individualized by a qualified clinician based on the type and severity of infection, patient's age, weight, renal and hepatic function, and clinical response. Do not self-medicate. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal and hepatic function. Use with caution and monitor for side effects. |
| Renal Impairment | Dose adjustment may be needed in patients with renal impairment. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose is one kit (Azithromycin 1000 mg + Ornidazole 750 mg). Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of af kit tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ergot alkaloids | Major | |
| Disulfiram | Major | |
| Antacids | Moderate | |
| Cyclosporine | Moderate | |
| Digoxin | Moderate | |
| Cimetidine | Minor | |
| Phenytoin | Minor | |
| Alcohol | Major | |
| Live vaccines | Moderate |
🚨 Major Interactions
- Warfarin
- Ergot alkaloids
- Disulfiram
⚡ Moderate Interactions
- Antacids containing aluminum or magnesium
- Cyclosporine
- Digoxin
🍷 Alcohol Interaction
Avoid alcohol consumption while taking this medicine and for at least 48 hours after the last dose. Ornidazole can cause a disulfiram-like reaction with alcohol, leading to severe nausea, vomiting, flushing, headache, and rapid heart rate.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Azithromycin, Ornidazole, or other macrolides/nitroimidazoles","Severe hepatic impairment","History of blood dyscrasias","Concurrent use with ergot alkaloids","First trimester of pregnancy (relative)"]
⚠️ Warnings & Precautions
["Avoid alcohol during and for 48 hours after therapy.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Use with caution in patients with seizure disorders.","May prolong QT interval; use with caution in patients with cardiac conditions.","Complete the full course as prescribed to prevent resistance.","Inform your doctor if you have liver or kidney disease.","Not recommended for children unless prescribed by a pediatrician."]
🤱 Lactation Safety
Azithromycin and Ornidazole are excreted in breast milk. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, diarrhea, and neurological symptoms. Seek immediate medical attention. Treatment is symptomatic and supportive. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not share it with others, even if they have similar symptoms. Avoid alcohol while taking this medicine and for at least 48 hours after the last dose, as it may cause a disulfiram-like reaction with Ornidazole. Inform your doctor if you have liver or kidney problems, heart rhythm disorders, or a history of seizures. Do not drive or operate heavy machinery if you experience dizziness or drowsiness. Complete the full course as prescribed, even if you feel better, to prevent recurrence and resistance. Store in a cool, dry place away from direct sunlight and out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to side effects such as dizziness, confusion, and liver or kidney toxicity. Dose adjustment may be needed based on renal and hepatic function. Monitor closely.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy while on this medicine. Both Azithromycin and Ornidazole should be used with caution during pregnancy. Discuss risks and benefits with your healthcare provider.
🏥 Post-Surgery Considerations
Inform your surgeon if you are taking this medicine before surgery. It may interact with anesthetics and other medications. Your doctor may advise stopping it temporarily.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with certain antibiotics or anesthetics used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you feel dizzy or weak. Light activity is fine if you feel up to it.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to take it when you can rest if needed.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor, even if you feel better. Stopping early may lead to recurrence of infection and antibiotic resistance. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of liver toxicity, peripheral neuropathy, and blood dyscrasias. It should only be used for the prescribed duration. Regular monitoring of liver and kidney function is advised if prolonged therapy is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help restore healthy gut and vaginal flora during and after antibiotic therapy.
Evidence: ModerateHelps prevent recurrence of infections.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Antibiotics may reduce the efficacy of live vaccines. Avoid live vaccines during therapy and for a few days after. Consult your doctor for specific advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 1-2 days, but complete the full course as prescribed.
A: Yes, take it with food to reduce stomach upset.
A: Take it as soon as you remember, but if it's almost time for the next dose, skip it and continue your schedule.
🤔 Common Patient Concerns
🔄 Substitutes for af kit tablet
View AllAlternative brands with exact same active ingredient:
-
afo kit 1000 mg/750 mg/150 mg tabletInd Swift Laboratories Ltd ₹41.25 61.7% CHEAPER
-
vaginobact 1000 mg/750 mg/150 mg tabletCipla Ltd ₹65.63 39.1% CHEAPER
-
femiriv 3 kit tabletEast African (India) Overseas ₹70.31 34.8% CHEAPER
-
termikit 1000 mg/750 mg/150 mg kitHelios Pharmaceuticals ₹84.00 22.1% CHEAPER
-
fm 3 kitEndocard India Pvt Ltd ₹89.06 17.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: AF Kit Tablet can cure any infection.
Fact: It is only effective against specific susceptible bacteria and protozoa. It should not be used for viral infections like colds or flu. - Myth: You can stop taking AF Kit Tablet once you feel better.
Fact: You must complete the full course as prescribed to prevent recurrence and resistance. - Myth: AF Kit Tablet is safe to take with alcohol.
Fact: Alcohol must be avoided as it can cause a severe disulfiram-like reaction.
🔄 Alternative Options
Generic Alternatives
- Azithromycin 1000 mg + Ornidazole 750 mg tablets (various manufacturers)
Brand Alternatives
- AF Kit Tablet (Systopic Laboratories Pvt Ltd)