Abortab 200mg Tablet (Mifepristone): Comprehensive Guide
When to Call Your Doctor IMMEDIATELY
- Heavy vaginal bleeding (soaking more than two pads per hour for more than two hours)
- Severe abdominal pain
- Fever or chills
- Foul-smelling vaginal discharge
- Signs of an allergic reaction (rash, itching, swelling, difficulty breathing)
- Dizziness or fainting
- Rapid heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is abortab 200mg tablet used for?
This medicine is a progesterone receptor antagonist used for medical termination of early pregnancy, typically in combination with misoprostol. It works by blocking progesterone, leading to detachment of the embryo and uterine contractions.
- Generic Name: Mifepristone
- Manufacturer: Bharat Serums & Vaccines Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 abortab 200mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मिफेप्रिस्टोन 200 मिलीग्राम युक्त एक टैबलेट है, जिसका उपयोग प्रारंभिक गर्भावस्था को समाप्त करने के लिए किया जाता है। यह आमतौर पर मिसोप्रोस्टोल के साथ मिलकर काम करती है। यह दवा केवल योग्य चिकित्सक की देखरेख में ही ली जानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट दर्द, मतली, उल्टी, दस्त, सिरदर्द, चक्कर आना और थकान शामिल हैं। गंभीर दुष्प्रभावों में अत्यधिक रक्तस्राव, संक्रमण, अपूर्ण गर्भपात और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं।
सुरक्षा सलाह: यह दवा केवल योग्य चिकित्सक की देखरेख में ही लें। यदि आपको एक्टोपिक गर्भावस्था, एड्रेनल अपर्याप्तता, या रक्तस्राव विकार है तो इसे न लें। इस दवा को लेते समय शराब और अंगूर के रस से बचें। इस दवा को लेने के बाद कम से कम 14 दिनों तक स्तनपान न करें।
💊 abortab 200mg tablet Uses & Benefits
[{"condition":"Medical termination of early pregnancy","description":"Used in combination with misoprostol for the termination of intrauterine pregnancy up to 70 days of gestation.","evidence":"Well-established"},{"condition":"Cushing's syndrome","description":"Used to treat endogenous Cushing's syndrome in patients who are not candidates for surgery or have not responded to surgery.","evidence":"Well-established"},{"condition":"Uterine fibroids","description":"May be used preoperatively to reduce fibroid size and associated symptoms.","evidence":"Moderate"},{"condition":"Breast cancer","description":"Investigated for use in certain types of breast cancer, particularly those with progesterone receptor positivity.","evidence":"Limited"}]
Off-label uses: [{"condition":"Meningioma","description":"Sometimes used off-label for inoperable meningiomas expressing progesterone receptors.","evidence":"Limited"},{"condition":"Endometriosis","description":"May be used off-label for pain associated with endometriosis.","evidence":"Limited"}]
Primary treatment for: Medical termination of early pregnancy
Also treats: Cushing's syndrome, Uterine fibroids, Breast cancer
📋 Drug Information
| Generic Name(s) | Mifepristone |
| Brand Name | Abortab |
| Manufacturer | Bharat Serums & Vaccines Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Anti-progesterone |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | The World Health Organization recommends mifepristone in combination with misoprostol for medical termination of pregnancy up to 70 days of gestation. |
| ICMR Guideline | The Indian Council of Medical Research has guidelines for medical termination of pregnancy that include the use of mifepristone and misoprostol. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a synthetic steroid that acts as a progesterone receptor antagonist. It binds with high affinity to the progesterone receptor, blocking the effects of progesterone. This leads to detachment of the embryo from the uterine lining, softening and dilation of the cervix, and increased uterine contractility. It also has antiglucocorticoid activity at higher doses.
Mechanism Steps
💡 How to Take abortab 200mg tablet
Strength: 200 mg immediate-release tablet
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. For termination of early pregnancy, a single 200 mg oral dose is typically used in combination with misoprostol. For Cushing's syndrome, doses may range from 300 mg to 1200 mg daily. Do not self-medicate. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustments are recommended for elderly patients, but use with caution due to potential comorbidities. |
| Renal Impairment | No dose adjustment is required for mild to moderate renal impairment. Use with caution in severe renal impairment. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. |
| Maximum Daily Dose | The maximum daily dose depends on the indication and must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of abortab 200mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Rifampicin | Major | |
| Warfarin | Major | |
| NSAIDs | Moderate | |
| Corticosteroids | Moderate | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin)
- Warfarin
⚡ Moderate Interactions
- NSAIDs
- Corticosteroids
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness, drowsiness, and gastrointestinal side effects. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to mifepristone","Confirmed or suspected ectopic pregnancy","Adrenal insufficiency","Bleeding disorders","Use of an intrauterine device","Chronic corticosteroid therapy","Inherited porphyria"]
⚠️ Warnings & Precautions
["This medicine must be used under the supervision of a qualified healthcare provider.","Do not use for termination of pregnancy beyond 70 days of gestation.","Ensure access to emergency medical care in case of heavy bleeding.","Avoid concurrent use with grapefruit juice.","Use effective contraception until next menstrual period.","Do not breastfeed for at least 14 days after taking this medicine."]
🤱 Lactation Safety
This medicine is excreted in breast milk. Breastfeeding should be avoided for at least 14 days after taking this medicine.
💊 Overdose Management
There is no specific antidote for overdose. In case of overdose, seek immediate medical attention. Treatment should be symptomatic and supportive.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
This medicine must only be taken under the supervision of a qualified healthcare provider. Do not take it if you have an ectopic pregnancy, an intrauterine device, adrenal insufficiency, or a bleeding disorder. Avoid alcohol and grapefruit juice while taking this medicine. Do not breastfeed for at least 14 days after taking this medicine. Use effective contraception until your next menstrual period. Follow up with your doctor as scheduled to confirm the termination is complete. Seek emergency care if you experience heavy bleeding, severe pain, or fever.
👴 Special Considerations for Elderly
💡 For Patients Above 65
This medicine is not typically used in elderly patients for termination of pregnancy. For other indications, use with caution due to potential comorbidities.
🤰 Pregnancy Planning (TTC)
This medicine is used for termination of pregnancy. If you are planning a pregnancy, consult your doctor before taking this medicine. Use effective contraception until your next menstrual period after treatment.
🏥 Post-Surgery Considerations
If you have recently had surgery, inform your doctor before taking this medicine. It may affect wound healing or interact with anesthetics.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may increase bleeding risk during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise and heavy lifting until bleeding stops and you feel fully recovered. Light activities are okay if you feel up to it.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
You may need to take time off work or school for a few days after taking this medicine. Avoid driving if you feel dizzy or fatigued.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects, seek immediate medical attention.
📅 Long-Term Use Effects
Long-term use of this medicine may affect liver function and adrenal function. Regular monitoring of liver enzymes and cortisol levels is recommended. When used for termination of pregnancy, it is typically a one-time treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A procedure to terminate pregnancy, which may be an option depending on the stage of pregnancy and medical history.
Evidence: Well-establishedWaiting for natural miscarriage, which may be an option in some cases of early pregnancy loss.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions reported. However, consult your doctor before receiving any vaccines while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, consult your doctor for dose adjustments. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The effects of this medicine begin within 24 to 48 hours after administration.
A: Common side effects include abdominal pain, nausea, vomiting, diarrhea, headache, dizziness, and fatigue.
A: Inform your doctor about all medications you are taking, as this medicine can interact with several drugs.
🤔 Common Patient Concerns
🔄 Substitutes for abortab 200mg tablet
View AllAlternative brands with exact same active ingredient:
-
medabon 200mg tabletSun Pharmaceutical Industries Ltd ₹20.25 94.5% CHEAPER
-
pregnot 200mg tabletLupin Ltd ₹46.88 87.3% CHEAPER
-
mifecon 200mg tabletSun Pharmaceutical Industries Ltd ₹59.77 83.8% CHEAPER
-
termipil 200mg kitAlkem Laboratories Ltd ₹60.00 83.7% CHEAPER
-
Relezed 200mg TabletZee Laboratories ₹79.68 78.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without medical supervision.
Fact: This medicine must only be taken under the supervision of a qualified healthcare provider. - Myth: This medicine is safe for self-induced abortion.
Fact: Self-administration can lead to serious complications. Always consult a doctor.
🔄 Alternative Options
Generic Alternatives
- Mifepristone 200 mg tablet
Brand Alternatives
- Mifegest 200 mg tablet
- Mifeprin 200 mg tablet
- Unwanted 200 mg tablet