cans lb tablet vt - Clindamycin (100mg) + Miconazole (200mg) medicine

cans lb tablet vt - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Ravenbhel Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is cans lb tablet vt used for?

Canfree V7 100mg/200mg Suppository (Clindamycin + Miconazole) is used to treat ANTI INFECTIVES. It contains Clindamycin (100mg) + Miconazole (200mg), which Clindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal sub. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Clindamycin + Miconazole
  • Manufacturer: Ravenbhel Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š cans lb tablet vt Uses & Benefits

Treatment of bacterial vaginosis and vulvovaginal candidiasis.

Off-label uses: Not applicable.

๐Ÿ“‹ Drug Information

Generic Name(s)Clindamycin + Miconazole
Brand NameCanfree V7 100mg/200mg Suppository
ManufacturerRavenbhel Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAntibiotic + Antifungal
Route of AdministrationVaginal suppository
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionSystemic absorption from vaginal mucosa is minimal for both drugs; local action predominates.
DistributionClindamycin distributes widely into tissues and fluids; miconazole has limited systemic distribution.
Protein BindingClindamycin: 90-94%; Miconazole: 90-93%
MetabolismClindamycin: hepatic via CYP3A4; Miconazole: hepatic via CYP3A4 and CYP2C9
Half-LifeClindamycin: 2-3 hours; Miconazole: 20-25 hours
ExcretionClindamycin: renal and biliary; Miconazole: primarily hepatic
BioavailabilityMinimal systemic bioavailability due to local administration
Onset of ActionWithin 24 hours
Peak Plasma TimeNot applicable (local action)
Duration of ActionUp to 24 hours per dose

How It Works

Clindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal subunit; Miconazole inhibits fungal ergosterol synthesis by inhibiting 14ฮฑ-demethylase.

Mechanism Steps

1Clindamycin binds to 50S ribosomal subunit, inhibiting peptide bond formation.
2Miconazole inhibits 14ฮฑ-demethylase, blocking ergosterol synthesis.
3Ergosterol depletion disrupts fungal cell membrane integrity.

๐Ÿ’ก How to Take cans lb tablet vt

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cans lb tablet vt

โœ… Common Side Effects

  • Vaginal burning
  • itching
  • irritation
  • abdominal cramps

๐Ÿšจ Serious Side Effects

  • Pseudomembranous colitis
  • severe allergic reactions

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • blood dyscrasias

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased INR and bleeding risk
CYP3A4 substrates Major Increased plasma levels of substrate
CYP2C9 substrates Major Increased plasma levels of substrate
Neuromuscular blocking agents Moderate Enhanced neuromuscular blockade
Oral contraceptives Moderate Reduced contraceptive efficacy
Antidiarrheal agents Minor Reduced absorption of clindamycin

๐Ÿšจ Major Interactions

  • Warfarin
  • CYP3A4 substrates
  • CYP2C9 substrates

โšก Moderate Interactions

  • Neuromuscular blocking agents
  • Oral contraceptives

โ„น๏ธ Minor Interactions

  • Antidiarrheal agents

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to clindamycin, miconazole, or any component; history of antibiotic-associated colitis.

๐Ÿ“Š Monitoring Parameters

Clinical response; signs of hypersensitivity or superinfection.

๐Ÿคฑ Lactation Safety

Clindamycin excreted in breast milk; miconazole minimal excretion. Use with caution.

๐Ÿ’Š Overdose Management

Overdose unlikely due to local use; if ingested, symptomatic treatment.

โฐ Missed Dose

Insert as soon as remembered; skip if almost time for next dose; do not double.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

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