cans 150mg/750mg kit
What is cans 150mg/750mg kit used for?
Canfree Kit (Fluconazole + Ornidazole) is used to treat GYNAECOLOGICAL. It contains Fluconazole (150mg) + Ornidazole (750mg), which Fluconazole inhibits fungal cytochrome P450 14ฮฑ-demethylase, preventing ergoste. Always consult your doctor before use. Take as prescribed.
- Generic Name: Fluconazole + Ornidazole
- Manufacturer: Ravenbhel Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ cans 150mg/750mg kit Uses & Benefits
Vaginal candidiasis, trichomoniasis, bacterial vaginosis
Off-label uses: Not well established
๐ Drug Information
| Generic Name(s) | Fluconazole + Ornidazole |
| Brand Name | Canfree Kit |
| Manufacturer | Ravenbhel Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Antifungal + Antiprotozoal |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Fluconazole inhibits fungal cytochrome P450 14ฮฑ-demethylase, preventing ergosterol synthesis; Ornidazole disrupts DNA structure in protozoa
Mechanism Steps
๐ก How to Take cans 150mg/750mg kit
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cans 150mg/750mg kit
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
- Metallic taste
๐จ Serious Side Effects
- Hepatotoxicity
- QT prolongation
- Severe skin reactions
- Blood dyscrasias
- Peripheral neuropathy
โ ๏ธ Rare Side Effects
- Anaphylaxis
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Seizures
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Sulfonylureas | Major | Increased hypoglycemia risk |
| Phenytoin | Major | Increased phenytoin levels |
| Cisapride | Major | QT prolongation risk |
| Terfenadine | Major | QT prolongation risk |
| Astemizole | Major | QT prolongation risk |
| Rifampin | Major | Reduced fluconazole efficacy |
| Oral contraceptives | Moderate | Reduced contraceptive efficacy |
| Theophylline | Moderate | Increased theophylline levels |
| Zidovudine | Moderate | Increased zidovudine levels |
| Losartan | Moderate | Reduced losartan efficacy |
| Statins | Moderate | Increased statin levels |
| Cimetidine | Minor | Reduced fluconazole absorption |
| Antacids | Minor | Reduced fluconazole absorption |
| Alcohol | Moderate | Disulfiram-like reaction |
๐จ Major Interactions
- Warfarin
- Sulfonylureas
- Phenytoin
- Cisapride
- Terfenadine
- Astemizole
- Rifampin
- CYP2C9 substrates
โก Moderate Interactions
- Oral contraceptives
- Theophylline
- Zidovudine
- Losartan
- Statins
โน๏ธ Minor Interactions
- Cimetidine
- Antacids
- H2 antagonists
๐ฝ๏ธ Food Interactions
No significant food interactions
๐ท Alcohol Interaction
Avoid alcohol due to disulfiram-like reaction with ornidazole
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to azoles or nitroimidazoles, pregnancy (first trimester), lactation, severe hepatic impairment
๐ Monitoring Parameters
Liver function tests, renal function, ECG (if high dose), blood glucose (in diabetics)
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Supportive care; gastric lavage; monitor ECG and liver function
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Helpful and effective medicine as per my experience. Always consult a doctor.
Helpful and effective medicine as per my experience. Always consult a doctor.
Effective and reliable. Worked as expected.
Found this to be a helpful product. Good results.
Helpful and effective medicine as per my experience. Always consult a doctor.