copod-b syrup - Terbutaline (1.25mg) + Bromhexine (2mg) medicine

Corun-B Syrup: Comprehensive Medicine Guide

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🏭 Mepfarma India Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for the combination in respiratory conditions.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or worsening of asthma symptoms
  • Chest pain or irregular heartbeat
  • Severe allergic reaction (rash, itching, swelling of face, lips, or throat)
  • Severe tremors or nervousness that interfere with daily activities
  • Blood in mucus or vomit
  • Persistent vomiting or inability to keep fluids down
  • Yellowing of skin or eyes (jaundice)

If experiencing severe symptoms, call emergency services immediately.

What is copod-b syrup used for?

This medicine is a combination of Terbutaline and Bromhexine used to treat respiratory conditions like asthma and bronchitis. It works by relaxing the airways and thinning mucus, making it easier to breathe and cough out mucus.

  • Generic Name: Terbutaline + Bromhexine
  • Manufacturer: Mepfarma India Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 copod-b syrup के बारे में (Hindi Summary)

उपयोग: यह दवा टर्ब्यूटलीन और ब्रोमहेक्सिन का संयोजन है, जिसका उपयोग अस्थमा, ब्रोंकाइटिस और अन्य श्वसन संबंधी समस्याओं के इलाज में किया जाता है। यह श्वास नलियों को फैलाकर और बलगम को पतला करके सांस लेने में आसानी प्रदान करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में कंपन, घबराहट, सिरदर्द, मतली और धड़कन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको एलर्जी, अनियमित दिल की धड़कन या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। सटीक खुराक के लिए मापने वाला कप या चम्मच उपयोग करें। यदि आपको चक्कर या कंपन महसूस हो तो वाहन चलाने या मशीनरी संचालित करने से बचें। हृदय रोग, उच्च रक्तचाप, मधुमेह या थायरॉइड की समस्या हो तो डॉक्टर को बताएं।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 copod-b syrup Uses & Benefits

[{"condition":"Bronchial asthma","description":"Helps relieve bronchospasm and loosen mucus, making breathing easier.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Provides symptomatic relief by dilating airways and thinning mucus.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Used to manage chronic cough and mucus production.","evidence":"Well-established"},{"condition":"Emphysema","description":"May help improve airflow and mucus clearance.","evidence":"Limited"}]

Off-label uses: []

Primary treatment for: Bronchial asthma

Also treats: Acute bronchitis, Chronic bronchitis, Emphysema

📋 Drug Information

Generic Name(s)Terbutaline + Bromhexine
Brand NameAskafex TR Suspension
ManufacturerMepfarma India Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassBronchodilator + Mucolytic
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep out of reach of children. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always shake the bottle well before measuring the dose.
2
Use a proper measuring cup or spoon; household spoons are not accurate.
3
Take this medicine with food if it causes stomach upset.
4
Do not exceed the prescribed dose; more is not better and can cause side effects.
5
If you have a history of heart disease, diabetes, or thyroid problems, inform your doctor before starting this medicine.
6
Avoid driving or operating machinery if you experience tremors or dizziness.
7
Do not stop this medicine abruptly without consulting your doctor, especially if you have been taking it for a long time.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Wheezing
This medicine is commonly prescribed for this.
Likely Use
✅
Cough with thick mucus
This medicine helps thin and clear mucus.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTerbutaline is well absorbed from the gastrointestinal tract after oral administration. Bromhexine is also rapidly absorbed from the gastrointestinal tract.
DistributionTerbutaline distributes widely into body tissues, including the lungs. Bromhexine is extensively distributed to the lungs, liver, and kidneys.
Protein BindingTerbutaline is approximately 25% bound to plasma proteins. Bromhexine is about 95% bound to plasma proteins.
MetabolismTerbutaline undergoes extensive first-pass metabolism in the liver, primarily by conjugation. Bromhexine is metabolized in the liver to several metabolites, including ambroxol.
Half-LifeThe elimination half-life of Terbutaline is approximately 3 to 4 hours. The elimination half-life of Bromhexine is about 1 hour, while its active metabolite ambroxol has a half-life of 10 to 12 hours.
ExcretionTerbutaline and its metabolites are primarily excreted in the urine. Bromhexine metabolites are mainly excreted in the urine.
BioavailabilityThe oral bioavailability of Terbutaline is approximately 10% due to first-pass metabolism. The bioavailability of Bromhexine is about 75-80%.
Onset of ActionBronchodilation from Terbutaline occurs within 30 minutes after oral administration. Bromhexine's mucolytic effect typically begins within 30 minutes to 1 hour.
Peak Plasma TimePeak plasma concentrations of Terbutaline are reached within 2 to 4 hours. Bromhexine peaks within 1 hour.
Duration of ActionThe bronchodilator effect of Terbutaline lasts for about 4 to 6 hours. Bromhexine's mucolytic effect lasts for approximately 6 to 8 hours.

How It Works

Terbutaline acts by selectively stimulating beta-2 adrenergic receptors in the bronchial smooth muscle, leading to relaxation and bronchodilation. Bromhexine works by increasing the production of serous fluid in the respiratory tract and breaking down the structure of mucus, thereby reducing its viscosity and making it easier to expel.

Mechanism Steps

1
Beta-2 receptor stimulation: Terbutaline binds to beta-2 adrenergic receptors on bronchial smooth muscle cells.
2
Increased cyclic AMP: This binding activates adenylate cyclase, increasing cyclic AMP levels within the cells.
3
Smooth muscle relaxation: Elevated cyclic AMP leads to relaxation of bronchial smooth muscles, resulting in bronchodilation.
4
Mucolytic action of Bromhexine: Bromhexine breaks down acidic mucopolysaccharide fibers in mucus, reducing its thickness and stickiness.
5
Enhanced mucus clearance: Thinner mucus is easier to cough up, helping to clear the airways.

💡 How to Take copod-b syrup

Strength: Each 5 mL of syrup contains Terbutaline 1.25 mg and Bromhexine 2 mg.

1Shake the bottle well before each use.
2Use the measuring cup or spoon provided with the medicine to measure the correct dose.
3Take the medicine orally, with or without food.
4If it upsets your stomach, take it with a meal or snack.
5After taking, rinse the measuring cup with water.
6Wash your hands after handling the medicine.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5 mL to 10 mL (one to two teaspoons) taken two to three times a day, or as directed by your doctor. The dose may be adjusted based on your condition and response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Use with caution and follow your doctor's advice.
Renal ImpairmentDose adjustment may be required in patients with severe renal impairment. Consult your doctor.
Hepatic ImpairmentDose adjustment may be required in patients with severe hepatic impairment. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 30 mL (6 teaspoons) in divided doses, or as prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of copod-b syrup

✅ Common Side Effects

Tremors (Common (5-10%))
Usually subsides with continued use. If bothersome, consult your doctor.
Nervousness (Common (5-10%))
Try relaxation techniques. If persistent, talk to your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if severe.
Nausea (Common (5-10%))
Take with food to reduce nausea.
Palpitations (Common (5-10%))
Report to your doctor if persistent or bothersome.

🚨 Serious Side Effects

Severe allergic reactions (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling, or difficulty breathing.
Irregular heartbeat (Rare (<0.1%))
Contact your doctor immediately if you feel palpitations or irregular pulse.
Worsening of asthma (Rare (<0.1%))
If breathing becomes more difficult, seek emergency care.

⚠️ Rare Side Effects

Hypokalemia
Report muscle weakness or cramps to your doctor.
Hyperglycemia
Monitor blood sugar if diabetic. Consult doctor if levels rise.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Furosemide Moderate
Digoxin Moderate
Tricyclic antidepressants Moderate
Ipratropium Minor

🚨 Major Interactions

  • Beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs)

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Digoxin
  • Tricyclic antidepressants

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and tremors associated with this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Terbutaline, Bromhexine, or any component of the formulation","Severe cardiac disease","Hyperthyroidism","Uncontrolled diabetes mellitus","Severe hepatic or renal impairment"]

⚠️ Warnings & Precautions

["Use with caution in patients with cardiovascular disorders, including coronary insufficiency and hypertension.","Caution in patients with diabetes mellitus as Terbutaline may increase blood glucose levels.","Caution in patients with hyperthyroidism as Terbutaline may exacerbate symptoms.","Caution in patients with seizure disorders.","Not recommended for children under 2 years of age unless directed by a doctor.","Do not exceed the recommended dose."]

🤱 Lactation Safety

Terbutaline and Bromhexine are excreted in breast milk in small amounts. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause severe tremors, palpitations, chest pain, and hypokalemia. Seek immediate medical attention. Treatment is supportive and symptomatic. Monitor vital signs and electrolyte levels.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Shake the bottle well before each use. Use a proper measuring cup or spoon to ensure accurate dosing. Avoid driving or operating heavy machinery if you feel dizzy or shaky after taking this medicine. Inform your doctor if you have heart disease, high blood pressure, diabetes, or thyroid problems before starting this medicine. Do not use this medicine for a longer duration than prescribed without consulting your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of this medicine, especially cardiac effects. Use with caution and monitor for side effects.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with certain anesthetic agents.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth or interact with certain medications used in dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Avoid triggers like smoke, dust, and cold air.
🥗
Practice breathing exercises to improve lung function.
😴
Stay hydrated to help thin mucus.
💧
Get adequate rest to support recovery.
🧘
Maintain a healthy diet rich in fruits and vegetables.
🌞
Use a humidifier if the air is dry.

🏋️ Exercise Considerations

Avoid strenuous exercise if you have breathing difficulties. Consult your doctor before starting any exercise program. Mild activities like walking may be beneficial.

🥗 Diet Recommendations

Include warm fluids like soups and herbal teas.
Avoid cold drinks and ice cream.
Eat a balanced diet rich in vitamins and minerals.
Limit processed foods and sugary drinks.

💼 Impact on Daily Work & Life

This medicine may cause tremors or dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is generally safe to continue desk work.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or your condition worsens, contact your doctor immediately. Your doctor will advise you on whether to stop or adjust the dose.

📅 Long-Term Use Effects

Long-term use of this medicine should be under medical supervision. Prolonged use of Terbutaline may lead to tolerance and reduced effectiveness. Regular monitoring of heart rate, blood pressure, and potassium levels is advised. Do not use for longer than prescribed without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and ease breathing.

Evidence: Well-established
Chest physiotherapy

Techniques to help clear mucus from the airways.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust your dosing schedule gradually as advised by your doctor. Do not leave it in a hot car or checked luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis
He was prescribed this medicine for a week. He noticed significant relief in cough and breathing within two days. He experienced mild tremors initially, which subsided after a few days. He was advised to take it with food to avoid nausea.
💡 Lesson: This medicine can provide quick relief in acute bronchitis, but mild side effects like tremors are common and usually temporary.
👤 A 50-year-old woman with chronic asthma
She used this medicine as part of her asthma management plan. It helped control her symptoms and reduced the frequency of asthma attacks. She was monitored for potassium levels due to concurrent diuretic use.
💡 Lesson: Regular monitoring and adherence to prescribed dose are key to managing chronic conditions effectively with this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 minutes to 1 hour after oral administration.

Q: Can I take this medicine with other medications?

A: Inform your doctor about all medications you are taking, as this medicine can interact with certain drugs like beta-blockers and MAOIs.

Q: Is this medicine safe during pregnancy?

A: Consult your doctor before using this medicine if you are pregnant or planning to become pregnant.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for copod-b syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure asthma permanently.
    Fact: This medicine provides symptomatic relief but does not cure asthma. It should be used as part of a comprehensive treatment plan.
  • Myth: It is safe to take this medicine without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under a doctor's supervision.

🔄 Alternative Options

Generic Alternatives

  • Terbutaline + Bromhexine syrup

📊 Comparison with Similar Medicines

[{"medicine":"Terbutaline + Bromhexine","composition":"Terbutaline 1.25 mg + Bromhexine 2 mg per 5 mL","uses":"Asthma, bronchitis","notes":"Combination provides bronchodilation and mucolysis."},{"medicine":"Terbutaline + Ambroxol","composition":"Terbutaline 1.25 mg + Ambroxol 15 mg per 5 mL","uses":"Asthma, bronchitis","notes":"Ambroxol is a metabolite of Bromhexine with similar mucolytic action."}]

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