asthelite pd syrup - Choline Theophyllinate (50mg) + Terbutaline (1.25mg) medicine

Asthelite PD Syrup: Complete Medicine Guide

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🏭 Litaka Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for combination use in asthma; limited for COPD.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Irregular or fast heartbeat
  • Severe chest pain
  • Difficulty breathing or worsening breathlessness
  • Seizures or convulsions
  • Severe dizziness or fainting
  • Signs of allergic reaction such as rash, swelling of face or throat
  • Muscle weakness or cramps

If experiencing severe symptoms, call emergency services immediately.

What is asthelite pd syrup used for?

This medicine is a combination bronchodilator syrup containing choline theophyllinate and terbutaline. It is used to treat wheezing and breathlessness in asthma and COPD. It works by relaxing the muscles in the airways. It is a prescription medicine and should only be taken under medical supervision.

  • Generic Name: Choline Theophyllinate + Terbutaline
  • Manufacturer: Litaka Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 asthelite pd syrup के बारे में (Hindi Summary)

उपयोग: यह दवा श्वसन मार्ग की मांसपेशियों को आराम देकर सांस लेने में मदद करती है। इसका उपयोग दमा (अस्थमा), क्रोनिक ब्रोंकाइटिस और सीओपीडी जैसी बीमारियों में घरघराहट, सीने में जकड़न और सांस फूलने के इलाज के लिए किया जाता है। यह एक प्रिस्क्रिप्शन दवा है और इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, सिरदर्द, बेचैनी, कंपन और धड़कन तेज होना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन दिल की धड़कन अनियमित होना, दौरा पड़ना या गंभीर एलर्जी हो सकती है। अगर आपको सीने में दर्द, सांस लेने में कठिनाई या बेहोशी महसूस हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से मात्रा न बढ़ाएं या घटाएं। चाय, कॉफी और कोला जैसे कैफीन युक्त पदार्थों का सेवन कम करें। अगर आपको हृदय रोग, उच्च रक्तचाप, मधुमेह या थायरॉइड की समस्या है, तो डॉक्टर को बताएं। अचानक तेज दमे के दौरे के लिए इस दवा का उपयोग न करें; रेस्क्यू इनहेलर का प्रयोग करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 asthelite pd syrup Uses & Benefits

[{"condition":"Bronchial asthma","description":"Used as an adjunct to inhaled corticosteroids or other controller medications to relieve bronchospasm and improve breathing in patients with reversible airway obstruction.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"May help reduce wheezing and breathlessness in selected patients with COPD when used under medical supervision.","evidence":"Moderate"},{"condition":"Acute bronchospasm","description":"Provides rapid relief of bronchospasm in acute exacerbations, though inhaled short-acting beta-2 agonists are preferred first-line.","evidence":"Limited"}]

Off-label uses: [{"condition":"Apnea of prematurity","description":"Methylxanthines like theophylline have been used off-label in neonatal apnea, but this syrup is not intended for that use.","evidence":"Limited"}]

Primary treatment for: Bronchial asthma

Also treats: Chronic obstructive pulmonary disease (COPD), Chronic bronchitis, Emphysema

📋 Drug Information

Generic Name(s)Choline Theophyllinate + Terbutaline
Brand NameAsthelite PD Syrup
ManufacturerLitaka Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassBronchodilator combination (Xanthine derivative + Beta-2 agonist)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not refrigerate.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always measure the dose accurately using a measuring cup or spoon provided with the syrup.
2
Take this medicine with food or milk to minimize stomach upset.
3
Avoid caffeine-containing foods and drinks as they can worsen side effects like tremor and palpitations.
4
Do not use this medicine as a rescue medication for acute asthma attacks; use your prescribed inhaler instead.
5
Inform your doctor if you have heart disease, high blood pressure, or diabetes before starting this medicine.
6
Keep a record of your symptoms and side effects to discuss with your doctor at follow-up.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Wheezing
This medicine is commonly prescribed for wheezing due to asthma or COPD.
Likely Use
✅
Chest tightness
It helps relax airway muscles and relieve chest tightness.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTerbutaline is well absorbed from the gastrointestinal tract after oral administration. Choline theophyllinate is rapidly absorbed and converted to theophylline. Food may affect the rate but not the extent of absorption.
DistributionBoth components distribute widely into body tissues and cross the placenta. Theophylline enters breast milk. Terbutaline has a volume of distribution of approximately 1.5 L/kg.
Protein BindingTheophylline is about 40% bound to plasma proteins. Terbutaline binding is approximately 25%.
MetabolismTheophylline is metabolized in the liver by cytochrome P450 enzymes (CYP1A2, CYP2E1, CYP3A4). Terbutaline undergoes conjugation in the liver and gut wall.
Half-LifeTheophylline half-life varies from 3 to 12 hours in adults, depending on age, liver function, and smoking status. Terbutaline half-life is approximately 3 to 4 hours.
ExcretionBoth drugs and their metabolites are excreted primarily in the urine. Theophylline excretion is increased in smokers and decreased in liver disease.
BioavailabilityOral bioavailability of terbutaline is approximately 10-15% due to first-pass metabolism. Theophylline bioavailability from choline theophyllinate is high, around 90%.
Onset of ActionBronchodilation begins within 15-30 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations occur within 1-2 hours for terbutaline and 1-3 hours for theophylline.
Duration of ActionBronchodilator effect lasts approximately 4-6 hours for terbutaline and up to 8-12 hours for theophylline.

How It Works

This medicine combines two bronchodilators with complementary mechanisms. Choline theophyllinate is a prodrug that releases theophylline, which inhibits phosphodiesterase enzymes, increasing cyclic AMP levels in bronchial smooth muscle and causing relaxation. Theophylline also blocks adenosine receptors, reducing bronchoconstriction and inflammation. Terbutaline is a selective beta-2 adrenergic agonist that stimulates beta-2 receptors on airway smooth muscle, leading to rapid relaxation and bronchodilation. Together, they widen the airways and ease breathing.

Mechanism Steps

1
Terbutaline binds beta-2 receptors: Terbutaline selectively stimulates beta-2 adrenergic receptors on airway smooth muscle cells.
2
Increased cyclic AMP: Beta-2 stimulation activates adenylate cyclase, raising cyclic AMP levels inside the muscle cells.
3
Smooth muscle relaxation: Elevated cyclic AMP leads to relaxation of bronchial smooth muscle and widening of the airways.
4
Theophylline inhibits phosphodiesterase: Theophylline, released from choline theophyllinate, inhibits phosphodiesterase enzymes, preventing breakdown of cyclic AMP.
5
Adenosine receptor blockade: Theophylline blocks adenosine receptors, reducing bronchoconstriction and mast cell mediator release.
6
Combined bronchodilation: The two mechanisms work together to produce sustained bronchodilation and symptom relief.

💡 How to Take asthelite pd syrup

Strength: Each 5 mL of syrup contains choline theophyllinate 50 mg and terbutaline 1.25 mg.

1Shake the bottle well before use.
2Use a measuring cup or spoon to measure the exact dose.
3Take with food or milk to reduce stomach upset.
4Swallow the syrup slowly; do not rush.
5Follow your doctor's dosing schedule strictly.

Dosage Information

Adult DosageThe usual adult dose is 5-10 mL (one to two teaspoons) taken two to three times daily, or as directed by your physician. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to therapy. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and monitor closely for cardiac and neurological side effects. Dose must be individualized by a qualified clinician.
Renal ImpairmentDose adjustment may be required in patients with renal impairment. Consult your doctor for individualized dosing.
Hepatic ImpairmentDose reduction may be necessary in patients with hepatic impairment due to reduced theophylline metabolism. Consult your doctor for individualized dosing.
Maximum Daily DoseThe maximum daily dose should not exceed the prescribed amount. Typically, theophylline doses above 10 mg/kg/day require monitoring. Follow your doctor's instructions strictly.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine-containing beverages
Avoid or limit
May increase nervousness and palpitations.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of asthelite pd syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk to reduce stomach upset. Consult doctor if persistent.
Tremor (Common (5-10%))
Usually decreases with continued use. Avoid caffeine. Consult doctor if bothersome.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if severe or persistent.
Palpitations (Common (5-10%))
Report to doctor if frequent or associated with chest discomfort.
Restlessness (Common (5-10%))
Avoid caffeine. Consult doctor if it interferes with sleep.

🚨 Serious Side Effects

Cardiac arrhythmias (Rare (<0.1%))
Seek immediate medical attention if you experience irregular heartbeat, chest pain, or fainting.
Seizures (Rare (<0.1%))
This is a medical emergency. Call emergency services immediately.
Severe hypokalemia (Rare (<0.1%))
Report muscle weakness, cramps, or palpitations to your doctor promptly.
Anaphylaxis (Very rare (<0.01%))
Seek emergency care immediately if you develop rash, swelling, or difficulty breathing.

⚠️ Rare Side Effects

Hyperglycemia
Monitor blood sugar if diabetic. Consult doctor if levels rise.
Hypotension
Report dizziness or fainting to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Tricyclic antidepressants Major
Corticosteroids Moderate
Diuretics Moderate
Digoxin Moderate
Cimetidine Moderate
Caffeine Minor
Phenytoin Minor

🚨 Major Interactions

  • Beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • Corticosteroids
  • Diuretics (loop and thiazide)
  • Digoxin
  • Cimetidine

🍷 Alcohol Interaction

Alcohol may increase the risk of gastrointestinal side effects and dizziness. Avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to theophylline, terbutaline, or any component","Severe cardiac arrhythmias","Uncontrolled hyperthyroidism","Acute severe asthma attack (requires rapid-acting inhaled bronchodilator)","Concurrent use with MAOIs"]

⚠️ Warnings & Precautions

["Use with caution in patients with cardiovascular disease, hypertension, or arrhythmias.","May cause hypokalemia; monitor potassium levels.","Avoid in patients with seizure disorders unless benefits outweigh risks.","Not recommended for children under 6 years without specialist advice.","Do not exceed prescribed dose due to risk of toxicity.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]

🤱 Lactation Safety

Both theophylline and terbutaline are excreted in breast milk. Caution is advised. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose can cause severe nausea, vomiting, tachycardia, arrhythmias, seizures, and hypokalemia. Seek emergency medical care immediately. Treatment is supportive and symptomatic, including activated charcoal, electrolyte correction, and management of arrhythmias.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without medical advice. Avoid caffeine-containing foods and drinks because they can increase nervousness and heart rate. Inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid disorders, or liver or kidney problems. Do not use this medicine for sudden severe asthma attacks; use your rescue inhaler instead. Keep out of reach of children. Store in a cool, dry place away from direct sunlight. Do not drive or operate heavy machinery if you feel dizzy or shaky after taking this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to cardiac and neurological side effects. Lower doses and close monitoring are recommended.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy. This medicine should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine before surgery. It may interact with anesthetic agents.

🦷 Dental Procedures

Inform your dentist about this medicine before any dental procedure. It may cause dry mouth or interact with local anesthetics.

💚 Lifestyle Tips for Better Results

🏃
Avoid smoking and exposure to secondhand smoke.
🥗
Use air purifiers and avoid allergens like dust and pollen.
😴
Practice breathing exercises and yoga to improve lung capacity.
💧
Maintain a healthy weight to reduce breathlessness.
🧘
Get adequate rest and sleep to support recovery.

🏋️ Exercise Considerations

Avoid strenuous exercise if you experience palpitations, dizziness, or breathlessness. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Include omega-3 fatty acids from fish or flaxseed.
Limit processed foods and excess salt.
Stay well hydrated.
Avoid caffeine-containing beverages.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tremor, which can affect driving or operating machinery. Avoid these activities until you know how the medicine affects you.

🛑 When to Stop This Medicine

Do not stop this medicine abruptly without consulting your doctor. If you experience severe side effects, contact your doctor immediately for guidance.

📅 Long-Term Use Effects

Long-term use of this medicine may require regular monitoring of heart rate, blood pressure, and serum potassium levels. Theophylline levels should be checked if available. Prolonged use without medical supervision can lead to toxicity. Regular follow-up with your doctor is essential.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Inhaled corticosteroids

First-line controller therapy for asthma.

Evidence: Well-established
Leukotriene receptor antagonists

Oral alternatives for asthma control.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. However, patients with chronic respiratory diseases should receive annual influenza and pneumococcal vaccines as advised by their doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust dosing times gradually in consultation with your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with chronic asthma
He was prescribed this medicine as an add-on to his inhaler. He noticed significant improvement in his night-time wheezing within a week. He learned to take it with breakfast and dinner to avoid stomach upset and to limit his coffee intake to prevent jitteriness.
💡 Lesson: Taking this medicine with food and avoiding caffeine improves tolerability and effectiveness.
👤 A 60-year-old woman with COPD
She started this medicine for her breathlessness. She experienced mild tremors initially, which reduced after a few days. Her doctor monitored her heart rate and potassium levels regularly. She was advised not to use it during acute exacerbations and to use her inhaler instead.
💡 Lesson: Regular monitoring and adherence to prescribed use are essential for safe and effective treatment.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 15-30 minutes after oral administration.

Q: Can I take it with other asthma medicines?

A: Yes, but only under your doctor's supervision. Some combinations may increase side effects.

Q: Is it safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can be used for sudden severe asthma attacks.
    Fact: This medicine is not a rescue inhaler. For acute attacks, use a rapid-acting inhaled bronchodilator and seek emergency care if needed.
  • Myth: It is safe to take extra doses if symptoms worsen.
    Fact: Taking more than the prescribed dose can cause serious heart and nervous system side effects. Always follow your doctor's instructions.

🔄 Alternative Options

Generic Alternatives

  • Choline theophyllinate + Terbutaline syrup (generic)

Brand Alternatives

  • Asthelite PD Syrup

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Choline Theophyllinate 50mg + Terbutaline 1.25mg per 5mL","onset":"15-30 minutes","duration":"4-12 hours"},{"medicine":"Salbutamol syrup","composition":"Salbutamol 2mg per 5mL","onset":"15-30 minutes","duration":"4-6 hours"}]

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