coflox 750mg tablet
What is coflox 750mg tablet used for?
Alciflox 500mg Tablet (Ciprofloxacin) is used to treat GASTRO INTESTINAL. It contains Ciprofloxacin (750mg), which Inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, preventin. Always consult your doctor before use. Take as prescribed.
- Generic Name: Ciprofloxacin
- Manufacturer: Macleods Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ coflox 750mg tablet Uses & Benefits
Urinary tract infections, respiratory tract infections, skin and soft tissue infections, bone and joint infections, gastrointestinal infections, septicemia, and anthrax.
Off-label uses: Prostatitis, epididymitis, pelvic inflammatory disease, and some mycobacterial infections.
๐ Drug Information
| Generic Name(s) | Ciprofloxacin |
| Brand Name | Alciflox 500mg Tablet |
| Manufacturer | Macleods Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Quinolones/ Fluroquinolones |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, preventing DNA replication, transcription, repair, and recombination.
Mechanism Steps
๐ก How to Take coflox 750mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of coflox 750mg tablet
โ Common Side Effects
- Nausea
- Diarrhea
- Headache
- Dizziness
- Insomnia
- Abdominal pain
๐จ Serious Side Effects
- Tendonitis or tendon rupture
- Peripheral neuropathy
- CNS effects (seizures, confusion)
- QT prolongation
- Clostridium difficile diarrhea
- Hypersensitivity reactions
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Interstitial nephritis
- Hepatitis
- Photosensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Tizanidine | Major | Increased risk of hypotension and sedation |
| Theophylline | Major | Increased theophylline levels, risk of toxicity |
| Warfarin | Major | Increased anticoagulant effect, bleeding risk |
| Caffeine | Major | Increased caffeine levels, CNS stimulation |
| NSAIDs | Major | Increased risk of CNS stimulation and seizures |
| Cyclosporine | Moderate | Increased nephrotoxicity risk |
| Methotrexate | Moderate | Increased methotrexate toxicity |
| Phenytoin | Moderate | Altered phenytoin levels |
| Glyburide | Moderate | Increased hypoglycemic effect |
| Probenecid | Moderate | Decreased renal excretion of ciprofloxacin |
| Diazepam | Minor | Possible increased diazepam effect |
| Metoprolol | Minor | Possible increased metoprolol effect |
| Omeprazole | Minor | Possible decreased ciprofloxacin absorption |
| Ranitidine | Minor | Possible decreased ciprofloxacin absorption |
๐จ Major Interactions
- Tizanidine
- Theophylline
- Warfarin
- Caffeine
- NSAIDs
โก Moderate Interactions
- Cyclosporine
- Methotrexate
- Phenytoin
- Glyburide
- Probenecid
โน๏ธ Minor Interactions
- Diazepam
- Metoprolol
- Omeprazole
- Ranitidine
๐ฝ๏ธ Food Interactions
Dairy products, calcium-fortified juices, and antacids reduce absorption; avoid concurrent administration.
๐ท Alcohol Interaction
No direct interaction, but alcohol may increase CNS side effects like dizziness.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to ciprofloxacin or any fluoroquinolone; concomitant use with tizanidine; history of tendon disorders related to fluoroquinolones.
๐ Monitoring Parameters
Renal function, hepatic function, blood counts, signs of tendonitis or tendon rupture, CNS effects, and QT interval if risk factors.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution, potential for adverse effects in nursing infants.
๐ Overdose Management
Supportive care; monitor ECG for QT prolongation; consider activated charcoal if recent ingestion; hemodialysis removes only 10-20%.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if close to next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for coflox 750mg tablet
View AllAlternative brands with exact same active ingredient (Ciprofloxacin (750mg)):
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Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
Found this to be a helpful product. Good results.
Good quality medicine. Satisfied with the outcome.
Found this to be a helpful product. Good results.