Aciloc 300 Tablet (Ranitidine 300mg): Complete Guide
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe abdominal pain that does not go away
- Difficulty breathing or swelling of face, lips, or throat
- Yellowing of skin or eyes (jaundice)
- Confusion, hallucinations, or extreme drowsiness
- Unusual bruising or bleeding
- Fever with sore throat or mouth ulcers
- Chest pain or irregular heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is aciloc 300 tablet used for?
This medicine contains ranitidine 300 mg, an H2 blocker that reduces stomach acid. It treats ulcers, GERD, and other acid-related conditions. It is taken orally, usually once daily at bedtime or as prescribed. It works within 1 hour and lasts up to 12 hours.
- Generic Name: Ranitidine
- Manufacturer: Cadila Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 aciloc 300 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा रैनिटिडीन 300 मिलीग्राम युक्त एक ओरल टैबलेट है, जिसका उपयोग पेट के अल्सर, एसिड रिफ्लक्स (जीईआरडी), और अम्लता से जुड़ी अन्य समस्याओं के इलाज के लिए किया जाता है। यह पेट में एसिड का उत्पादन कम करती है, जिससे जलन और दर्द में राहत मिलती है और घाव भरने लगते हैं। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: आमतौर पर यह दवा सुरक्षित मानी जाती है, लेकिन कुछ लोगों को सिरदर्द, चक्कर आना, कब्ज, दस्त, या पेट में असहजता हो सकती है। ये लक्षण आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। यदि आपको असामान्य खून बहना, चकत्ते, सूजन, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे पानी के साथ पूरा निगलें, चबाएं नहीं। इसे भोजन के साथ या बिना भोजन के लिया जा सकता है, लेकिन हर दिन एक ही समय पर लें। शराब और धूम्रपान से बचें क्योंकि ये पेट की जलन बढ़ा सकते हैं। यदि आपको गुर्दे या यकृत की समस्या है, तो डॉक्टर को बताएं। अन्य दवाओं के साथ लेने से पहले डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 aciloc 300 tablet Uses & Benefits
[{"condition":"Duodenal ulcer","description":"This medicine is used to treat active duodenal ulcers and to prevent their recurrence by reducing stomach acid.","evidence":"Well-established"},{"condition":"Gastric ulcer","description":"It helps heal benign gastric ulcers and relieve associated pain by decreasing acid secretion.","evidence":"Well-established"},{"condition":"Gastroesophageal reflux disease (GERD)","description":"This medicine reduces heartburn and acid regurgitation by lowering stomach acid production.","evidence":"Well-established"},{"condition":"Zollinger-Ellison syndrome","description":"It is used to manage excessive acid secretion in this rare condition.","evidence":"Well-established"},{"condition":"Erosive esophagitis","description":"This medicine helps heal acid-induced damage to the esophagus.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prevention of stress ulcers in critically ill patients","description":"Sometimes used off-label in hospital settings to prevent stress-related gastrointestinal bleeding.","evidence":"Limited"},{"condition":"Chronic urticaria","description":"Occasionally used off-label as an add-on therapy for hives that do not respond to antihistamines.","evidence":"Limited"}]
Primary treatment for: Peptic ulcer disease
Also treats: Gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, Erosive esophagitis
📋 Drug Information
| Generic Name(s) | Ranitidine |
| Brand Name | Aciloc 150 Tablet |
| Manufacturer | Cadila Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | H2 Receptor Blocker |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by competitively blocking histamine H2 receptors located on the parietal cells of the stomach. By binding to these receptors, it prevents histamine from stimulating acid production. This leads to a reduction in both basal and stimulated gastric acid secretion, including that triggered by food, caffeine, and other stimuli. As a result, the stomach lining is less irritated, and ulcers and inflamed tissues have a chance to heal. The effect is reversible and dose-dependent.
Mechanism Steps
💡 How to Take aciloc 300 tablet
Strength: Immediate-release oral tablet containing 300 mg of ranitidine.
Dosage Information
| Adult Dosage | The usual adult dose for active duodenal ulcer is 300 mg once daily at bedtime or 150 mg twice daily. For maintenance, 150 mg at bedtime is common. For GERD, 150 mg twice daily is often used. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced renal function, which can increase the risk of side effects. Dose adjustment may be necessary based on renal function. Consult your doctor for appropriate dosing. |
| Renal Impairment | In patients with moderate to severe renal impairment (creatinine clearance less than 50 mL/min), the dose should be reduced. The usual recommendation is 150 mg once daily or 150 mg every 24 hours. For severe impairment, further reduction may be needed. Consult your doctor for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, no specific dose adjustment is usually required, but caution is advised. Monitor for side effects. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 300 mg for most indications, but higher doses may be used in Zollinger-Ellison syndrome under close medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of aciloc 300 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Itraconazole | Major | |
| Atazanavir | Major | |
| Warfarin | Moderate | |
| Phenytoin | Moderate | |
| Theophylline | Moderate | |
| Antacids | Minor | |
| Metoclopramide | Minor |
🚨 Major Interactions
- Ketoconazole
- Itraconazole
- Atazanavir
⚡ Moderate Interactions
- Warfarin
- Phenytoin
- Theophylline
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases stomach acid production and can irritate the stomach lining, which may reduce the effectiveness of this medicine and worsen your symptoms. It can also increase the risk of stomach bleeding.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to ranitidine or any component of the formulation","History of acute porphyria"]
⚠️ Warnings & Precautions
["Use with caution in patients with renal impairment; dose reduction may be necessary.","Use with caution in patients with hepatic impairment.","Elderly patients may be more susceptible to confusion and other central nervous system effects.","This medicine may mask symptoms of stomach cancer; ensure malignancy is ruled out before starting treatment.","Do not use for prolonged periods without medical supervision.","Avoid alcohol and smoking as they may worsen your condition.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Keep out of reach of children."]
🤱 Lactation Safety
This medicine is excreted in human breast milk. It is generally considered safe for use during breastfeeding, but the amount ingested by the infant is small. However, consult your doctor before use, as monitoring of the infant for potential side effects may be advised.
💊 Overdose Management
Overdose with this medicine is rare and usually produces no severe symptoms. However, if a large amount is ingested, seek immediate medical attention. Treatment is supportive and symptomatic. Gastric lavage may be considered if the overdose is recent. Monitor vital signs and provide supportive care. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without medical advice. Swallow the tablet whole with a glass of water; do not crush or chew it. You may take it with or without food, but taking it at the same time each day helps maintain steady levels. Avoid alcohol while taking this medicine because it can worsen stomach irritation and increase acid production. Do not smoke, as smoking increases stomach acid and may reduce the effectiveness of this medicine. If you have kidney or liver problems, your doctor may need to adjust your dose. Inform your doctor about all other medicines you are taking, especially ketoconazole, itraconazole, atazanavir, or blood thinners. Do not use this medicine for longer than recommended without consulting your doctor. Keep this medicine out of reach of children and store it at room temperature away from moisture and heat. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for your next dose. Never double the dose to make up for a missed one.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to experience confusion, dizziness, and other central nervous system effects. Dose adjustment may be needed based on kidney function. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is classified as Pregnancy Category B, meaning it is generally considered safe, but use only if clearly needed. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to prevent stress ulcers. Follow your doctor's instructions carefully. Inform your surgeon if you are taking this medicine before any surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It does not usually interfere with dental procedures, but your dentist may need to know for your safety.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, if you experience dizziness or fatigue, avoid strenuous activities until you know how the medicine affects you. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness in some people. If affected, avoid driving or operating heavy machinery until you know how it affects you. Otherwise, it usually does not interfere with daily activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. Your doctor will advise you on when and how to safely stop.
📅 Long-Term Use Effects
Long-term use of this medicine may rarely lead to vitamin B12 deficiency, breast enlargement in men, or blood disorders. Regular monitoring by your doctor is advised if you need to take it for an extended period. Do not use it for longer than recommended without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Medicines like omeprazole or pantoprazole may be used if H2 blockers are not effective.
Evidence: Well-establishedDiet changes, weight loss, and avoiding trigger foods can help manage acid reflux.
Evidence: Well-establishedIn severe cases, surgery may be considered for GERD or ulcers.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled. Consult your doctor if you have any concerns.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, adjust your dosing schedule gradually; consult your doctor for specific advice. Check local customs regulations regarding prescription medicines before you travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts reducing stomach acid within 1 hour after taking it. You may feel relief from heartburn and pain within a few hours, but full healing of ulcers may take several weeks.
A: Yes, but only as prescribed by your doctor. Long-term daily use should be monitored by a healthcare professional.
A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: This medicine can interact with certain drugs like ketoconazole, itraconazole, atazanavir, warfarin, phenytoin, and theophylline. Always inform your doctor about all medicines you are taking.
A: Do not stop without consulting your doctor. Completing the full course is important to ensure proper healing and prevent recurrence.
🤔 Common Patient Concerns
🔄 Substitutes for aciloc 300 tablet
View AllAlternative brands with exact same active ingredient:
-
afdiloc 300mg tabletAnglo-French Drugs & Industries Ltd ₹2.81 95.4% CHEAPER
-
veran 300mg tabletVega Pharma ₹6.56 89.4% CHEAPER
-
gertac 300mg tabletZydus Cadila ₹7.81 87.3% CHEAPER
-
renitab 300mg tabletMicro Labs Ltd ₹8.16 86.8% CHEAPER
-
zantid 300mg tabletJarson Pharmaceuticals ₹8.33 86.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Aciloc 300 is a painkiller.
Fact: It is not a painkiller; it reduces stomach acid to treat acid-related conditions. - Myth: You can stop taking it as soon as you feel better.
Fact: You should complete the full course as prescribed to ensure proper healing and prevent recurrence. - Myth: It is safe to take indefinitely without monitoring.
Fact: Long-term use should be monitored by a doctor due to potential side effects.
🔄 Alternative Options
Generic Alternatives
- Ranitidine 300 mg tablet
Brand Alternatives
- Aciloc 300 tablet