algesia cr 200mg/20mg capsule - Aceclofenac (200mg) + Rabeprazole (20mg) medicine

algesia cr 200mg/20mg capsule - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Macleods Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is algesia cr 200mg/20mg capsule used for?

Altraday Capsule SR (Aceclofenac + Rabeprazole) is used to treat PAIN ANALGESICS. It contains Aceclofenac (200mg) + Rabeprazole (20mg), which Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Rabepraz. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Aceclofenac + Rabeprazole
  • Manufacturer: Macleods Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š algesia cr 200mg/20mg capsule Uses & Benefits

Rheumatoid arthritis, Osteoarthritis, Ankylosing spondylitis, Pain and inflammation with GI protection

๐Ÿ“‹ Drug Information

Generic Name(s)Aceclofenac + Rabeprazole
Brand NameAltraday Capsule SR
ManufacturerMacleods Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAIDs + Proton Pump Inhibitors
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAceclofenac: Well absorbed orally; Rabeprazole: Rapidly absorbed after oral administration
DistributionAceclofenac: Widely distributed; Rabeprazole: High plasma protein binding
Protein BindingAceclofenac: >99%; Rabeprazole: ~96%
MetabolismAceclofenac: Hepatic via CYP2C9; Rabeprazole: Hepatic via CYP2C19 and CYP3A4
Half-LifeAceclofenac: ~4 hours; Rabeprazole: ~1-2 hours
ExcretionAceclofenac: Renal (primarily) and fecal; Rabeprazole: Renal (90%) and fecal
BioavailabilityAceclofenac: ~100%; Rabeprazole: ~52%
Onset of ActionAceclofenac: ~30 minutes; Rabeprazole: ~1 hour
Peak Plasma TimeAceclofenac: 1-3 hours; Rabeprazole: 2-4 hours
Duration of ActionAceclofenac: ~12 hours; Rabeprazole: ~24 hours

How It Works

Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Rabeprazole inhibits H+/K+ ATPase in gastric parietal cells, reducing gastric acid secretion

Mechanism Steps

1Aceclofenac inhibits COX enzymes, decreasing prostaglandin synthesis
2Reduced prostaglandins lead to decreased inflammation and pain
3Rabeprazole irreversibly binds to H+/K+ ATPase

๐Ÿ’ก How to Take algesia cr 200mg/20mg capsule

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of algesia cr 200mg/20mg capsule

โœ… Common Side Effects

  • Nausea
  • Dyspepsia
  • Headache
  • Diarrhea
  • Abdominal pain

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Renal impairment
  • Cardiovascular events
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Agranulocytosis
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

๐Ÿšจ Major Interactions

  • Warfarin
  • Methotrexate
  • Lithium
  • CYP2C19 inhibitors (e.g., fluconazole)

โšก Moderate Interactions

  • Aspirin
  • Clopidogrel
  • Diuretics
  • ACE inhibitors

โ„น๏ธ Minor Interactions

  • Antacids
  • Sucralfate

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption of aceclofenac; rabeprazole absorption unaffected

๐Ÿท Alcohol Interaction

Increased risk of GI bleeding with aceclofenac

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to NSAIDs or PPIs, Active peptic ulcer, Severe renal impairment, History of GI bleeding, Third trimester pregnancy

๐Ÿ“Š Monitoring Parameters

LFT, RFT, CBC, Blood pressure, GI symptoms

๐Ÿคฑ Lactation Safety

Aceclofenac: Excreted in milk, use caution; Rabeprazole: Excreted in milk, use caution

๐Ÿ’Š Overdose Management

Symptomatic and supportive; gastric lavage if recent; monitor renal function

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

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