coefsh 150 iu injection
What is coefsh 150 iu injection used for?
Coefsh 75IU (Recombinant follicle stimulating hormone) is used to treat GYNAECOLOGICAL. It contains Recombinant follicle stimulating hormone (150IU), which Binds to FSH receptors on ovarian granulosa cells, stimulating follicular develo. Always consult your doctor before use. Take as prescribed.
- Generic Name: Recombinant follicle stimulating hormone
- Manufacturer: Koye Pharmaceuticals Pvt ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ coefsh 150 iu injection Uses & Benefits
Anovulatory infertility, controlled ovarian hyperstimulation for assisted reproductive technologies (ART), hypogonadotropic hypogonadism.
Off-label uses: Male hypogonadotropic hypogonadism (spermatogenesis induction), idiopathic oligospermia.
๐ Drug Information
| Generic Name(s) | Recombinant follicle stimulating hormone |
| Brand Name | Coefsh 75IU |
| Manufacturer | Koye Pharmaceuticals Pvt ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Gonadotropins |
| Route of Administration | Subcutaneous or intramuscular injection. |
| Storage | Store at 2-8ยฐC (refrigerate). Do not freeze. Protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Binds to FSH receptors on ovarian granulosa cells, stimulating follicular development and estrogen production.
Mechanism Steps
๐ก How to Take coefsh 150 iu injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of coefsh 150 iu injection
โ Common Side Effects
- Injection site reactions
- Headache
- Nausea
- Abdominal pain
- Ovarian cysts
- Mild OHSS
๐จ Serious Side Effects
- Severe OHSS
- Ovarian torsion
- Pulmonary embolism
- Stroke
- Multiple pregnancy
โ ๏ธ Rare Side Effects
- Allergic reactions
- Anaphylaxis
- Ovarian hyperstimulation syndrome with pleural effusion
- Thromboembolism
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Clomiphene citrate | Major | Increased risk of ovarian hyperstimulation syndrome (OHSS) |
| GnRH agonists | Major | Altered response to FSH; requires dose adjustment |
| GnRH antagonists | Major | Reduced FSH efficacy; may require higher doses |
| Human chorionic gonadotropin (hCG) | Major | Induces final follicular maturation and ovulation; risk of OHSS |
| Aromatase inhibitors | Moderate | Additive effect on follicular development |
| Tamoxifen | Moderate | Potential additive effect on ovarian stimulation |
| Oral contraceptives | Minor | May suppress endogenous FSH, reducing efficacy |
| Progestins | Minor | May alter endometrial response |
๐จ Major Interactions
- Clomiphene citrate
- GnRH agonists
- GnRH antagonists
- Human chorionic gonadotropin (hCG)
โก Moderate Interactions
- Aromatase inhibitors
- Tamoxifen
โน๏ธ Minor Interactions
- Oral contraceptives
- Progestins
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
No known interaction; however, alcohol may affect hormone levels.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Pregnancy, lactation, ovarian cysts, ovarian enlargement, hypersensitivity, primary ovarian failure, uncontrolled thyroid/adrenal disorders, tumors of hypothalamus/pituitary/ovary/uterus/breast.
๐ Monitoring Parameters
Serum estradiol levels, ultrasound monitoring of follicular growth, endometrial thickness, signs of OHSS.
๐คฑ Lactation Safety
Not recommended; may suppress lactation.
๐ Overdose Management
Discontinue treatment; monitor for OHSS; supportive care including fluid management and hospitalization if severe.
โฐ Missed Dose
Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose. Consult physician.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for coefsh 150 iu injection
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Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Helpful and effective medicine as per my experience. Always consult a doctor.
Helpful and effective medicine as per my experience. Always consult a doctor.
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
Found this to be a helpful product. Good results.